201244748 六、發明說明： 【發明所屬之技術領域】 [0001] 本發明係有關於提供抗氧化組合物，尤其是有關於一種 先將活性粉體與多元醇類、酒精、乙氧基乙二醇、乙氧 基乙二醇衍生物等等混合，隔絕水氣的滲入，使其能減 緩其氧化變黃之情況，進而達到改善使用者皮膚斑點及 暗沉之效果目的之抗氧化組合物。 [先前技術3 [0002] 抗氧化劑是能減缓或防止氧化作用的分子。氧化是一種 使電子自物質轉移至氧化劑的化學反應，抗氧化劑通常 是還原劑，例如硫醇、抗壞血酸、多盼類。雖然氧化反 應十分重要，但它也能對生命體造成傷害；因此，動植 物演化出多種抗氧化劑，如常見的穀胱甘肽、維生素C與 維生素E，過氧化氫酶、超氧化物歧化酶等酶，以及各種 過氧化酶等等。 抗氧化劑廣泛地應用於食品、醫藥、飼料、化工等領域 ，在日常生活上十分常見。而抗氧化劑的生產技術一直 受到人們的重視與關注，並不斷研發、尋找新的物質。 然而儘管目前抗氧化劑種類眾多，卻還是存在容易因水 氣滲漏而使其内活性成份受到氧化而變黃的缺點。 因此，如何提供一種能減緩活性成份氧化變黃狀況之抗 氧化劑，是發明人極欲解決的課題。 【發明内容】 [0003] 有鑑於以往抗氧化劑之不完善，發明人經長時間不斷的 研究開發，終於研發出此種可以先將活性劑與多元醇類 1011023# WA〇101 第4頁/共12頁 1012004348-0 201244748 、酒精、乙氧基乙二醇、乙氧基乙二醇衍生物等等，進 而達到減缓其氧化變黃之情況之抗氧化組合物。 本發明抗氧化組合物，其組成係包括：一活性粉體，其 係選自維他命c、維他命c衍生物、熊果素、熊果素衍生 物、寡胜肽粉末（如：榖胱甘肽、肌肽等）上述之一至 數種；一溶劑，其係選自多元醇類、酒精、乙氧基乙二 醇、乙氧基乙二醇衍生物上述之一至數種；以及一選擇 性添加物，其係選自具抗氧化性之物質、具抓取自由基 之物質、具金屬螯合性之物質、具UV防曬物質上述之一 至數種。 本發明之主要目的在於藉由以上之組成，使活性粉體中 的活性成份先與溶劑混合，而能隔絕水氣的滲入，有效 減緩其氧化變黃之情況；再讓使用者將其抗氧化組合物 使用於皮膚上，則可達到改善皮膚斑點及暗沉之效果。 為了能讓審查員能更易於了解本發明之特點，請參閱本 發明實施方式之說明。 【實施方式】 [0004] 本發明抗氧化組合物，其組成係包括：一活性粉體，其 係選自維他命C、維他命C衍生物、熊果素、熊果素衍生 物、寡胜肽粉末（如：榖胱甘肽、肌肽等）上述之一至 數種；一溶劑，其係選自多元醇類、酒精、乙氧基乙二 醇、乙氧基乙二醇衍生物上述之一至數種；以及一選擇 性添加物，其係選自具抗氧化性之物質、具抓取自由基 之物質、具金屬螯合性之物質、具UV防曬物質上述之一 至數種；藉由以上之組成，使活性粉體中的活性成份先 與溶劑混合，而能隔絕水氣的滲入，有效減緩其氧化變 1012004348-0 10110239#單編號A0101 第5頁/共12頁 201244748 、之清况，再讓使用者將其抗氧化組合物使用於皮膚上 則可達到改善皮膚斑點及暗沉之效果。 本發明杬氧化組合物，其中，多元醇類可以選自丙二醇 、丙二醇、丁二醇、雙丙甘醇、三羥曱基乙烷、木糖醇 之上述之一至數種。 本發明抗氧化組合物，其中，具抗氧化性之物質可以選 自汽酮類（Flavonoids，如：柑橘類水果、漿果、銀杏葉 、洋蔥或黑巧克力等）、吲哚類（jnd〇丨es)、石_胡蘿蔔 素（冷-Carotene，如：毛棕櫚油、芒果、哈密瓜或波菜 等）、金雀異黃素（genistein)、花青素 (Anthocyanidin)、蕃益紅素（LyCopene ，如紅蘿蔔、 西瓜或木瓜等）、維他命E、葡萄籽油、左旋維他命c、含 笨環或雙鍵結構之物質之上述之一至數種。 本發明抗氧化組合物，其中，具抓取自由基之物質可以 選自威耽甘狀、肌狀（含Imidazole ring)、含組胺酸 (Histidine)、酷胺酸（Tyrosine)、色胺酸 (Tryptophan)的胜肽或蛋白質序列、含imidaz〇le ring、笨環結構之物質之上述之一至數種。 本發明抗氧化組合物，其中，具有金屬螯合能力之物質 可以選自EDTA(乙二胺四乙酸）' 檸檬酸、葡萄糖酸、或 酒石酸（右旋L-酒石酸、左旋L-酒石酸、内消旋酒石酸） 之上述之一至數種。 本發明抗氧化組合物，其中，該活性粉體的重量百分比 (%. w/w)為15%〜70% ;該溶劑的重量百分比（％. w/w)為 30%〜85% ;該選擇性添加物的重量百分比（％. w/w)為 0. 1%〜0. 5%。 1011023#^ A0101 第6頁/共12頁 1012004348-0 201244748 本發明抗氧化組合物，其中，可再包含美白成份，該成 份係選自於對苯二酚、麴酸、熊果素、杜鵑花酸等等上 述的至少一種；可再包含抗皺成份，該成份係選自於果 酸、維他命A、維他命B3等等上述的至少一種；可再包含 保溼成份，該成份係選自於玻尿酸、胺基酸、甘油等等 上述的至少一種。 本發明抗氧化組合物，其中，可再包含抗菌成份，該成 份係選自於椰子油、茶樹精油、天然柑橘、檸檬酸、植 物糖苷、芭樂葉上述的至少一種；可再包含營養成份， 該成份係選自於迷迭香提取物、紫蘇草提取物、蜜蜂花 草提取物、蘆薈、人參萃取物、銀杏提取物、金縷梅提 取物、水解小麥蛋白、金盞花攝取物、酪梨油、荷荷芭 油、山楂含黃_衍生物、花青色素、白花青衍生物、三 帖酸、皂角甘、單寧、烴基安息香酸鹽、脂肪酸、杏核 油、壬二酸、琉璃苣油、三酸甘油S旨、璃苣油、氫化大 豆甘油酯、乳酸、亞麻仁油酸、維他命K、棕櫚酸維他命 A素上述的至少一種；可再包含抗腐蝕成份，該成份係選 自於二甲矽油、鈦礦石、一異丙醇胺的至少一種；可再 包含美白成份，該成份係選自於對苯二酚、麴酸、熊果 素、杜鵑花酸上述的至少一種。 以上所述僅是藉由較佳實施例詳細說明本發明，然而對 於該實施例所作的任何修改與變化，例如活性粉體、溶 劑之種類與各重量百分比或是本發明抗氧化組合物之應 用等等之變化均不脫離本發明之精神與範圍。 由以上詳細說明可使熟知本項技藝者明瞭本發明的確可 達成前述之目的，實已符合專利法之規定，爰依法提出 1{)11()239#單編號A0101 第7頁/共12頁 1012004348-0 201244748 發明專利申請。 【圖式簡單說明】 [0005] 【主要元件符號說明】 [0006] 單編號 A0101 第8頁/共12頁 1012004348-0201244748 VI. Description of the Invention: [Technical Field of the Invention] [0001] The present invention relates to the provision of an antioxidant composition, and more particularly to an active powder and a polyol, an alcohol, an ethoxyethylene glycol, and the like. An antioxidant composition which is mixed with an ethoxylated ethylene glycol derivative or the like to prevent the infiltration of moisture, thereby slowing down the oxidative yellowing, thereby achieving the effect of improving the skin spots and dullness of the user. [Prior Art 3 [0002] An antioxidant is a molecule capable of slowing or preventing oxidation. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidant. The antioxidant is usually a reducing agent such as mercaptan, ascorbic acid, and polyantigen. Although the oxidation reaction is very important, it can also cause damage to living organisms; therefore, animals and plants evolve a variety of antioxidants, such as common glutathione, vitamin C and vitamin E, catalase, superoxide dismutase, etc. Enzymes, as well as various peroxidases and the like. Antioxidants are widely used in food, medicine, feed, chemical and other fields, and are very common in daily life. The production technology of antioxidants has always been valued and paid attention to, and research and development, and the search for new substances. However, in spite of the large variety of antioxidants, there are still disadvantages in that the active components are easily oxidized and yellowed due to moisture leakage. Therefore, how to provide an antioxidant which can alleviate the oxidative yellowing of an active ingredient is an object which the inventors are eager to solve. SUMMARY OF THE INVENTION [0003] In view of the imperfection of the past antioxidants, the inventors have been researching and developing for a long time, and finally developed this kind of active agent and polyols 1011023# WA〇101 Page 4 / Total 12 pages 1012004348-0 201244748, alcohol, ethoxy glycol, ethoxy glycol derivatives, etc., in order to achieve an antioxidant composition that slows down its oxidative yellowing. The antioxidant composition of the present invention comprises: an active powder selected from the group consisting of vitamin C, vitamin C derivative, arbutin, arbutin derivative, oligopeptide powder (eg, glutathione, carnosine, etc.) One to several of the above; a solvent selected from the group consisting of a polyol, an alcohol, an ethoxyethylene glycol, an ethoxyethylene glycol derivative, and one or more of the above; and a selective additive, which is selected One or several of the above-mentioned substances having an antioxidant property, a substance having a radical-trapping property, a substance having a metal chelate property, and a UV sunscreen substance. The main object of the present invention is to make the active ingredient in the active powder first mixed with the solvent by the above composition, and can infiltrate the infiltration of water vapor, effectively slow down the oxidation and yellowing; and let the user antioxidize it. When the composition is applied to the skin, the effect of improving skin spots and dullness can be achieved. In order to make it easier for the examiner to understand the features of the present invention, please refer to the description of the embodiments of the present invention. [Embodiment] [0004] The antioxidant composition of the present invention comprises: an active powder selected from the group consisting of vitamin C, vitamin C derivative, arbutin, arbutin derivative, oligopeptide powder (eg: 榖) Glutathione, carnosine, etc.) one to several of the above; a solvent selected from the group consisting of a polyol, an alcohol, an ethoxyethylene glycol, an ethoxy glycol derivative, one or more of the above; and a selection a sexual additive selected from the group consisting of an antioxidant substance, a substance having a free radical scavenging property, a substance having a metal chelate property, and one or more of the above-mentioned UV sunscreen substances; The active ingredient in the body is first mixed with the solvent, and can infiltrate the infiltration of water vapor, effectively slowing down the oxidation of the 1012004348-0 10110239# single number A0101 page 5 / 12 pages 201244748, and then let the user put it The anti-oxidation composition can be used on the skin to improve the skin spots and dullness. The oxime oxidizing composition of the present invention, wherein the polyhydric alcohol may be one or more selected from the group consisting of propylene glycol, propylene glycol, butylene glycol, dipropylene glycol, trihydroxydecylethane, and xylitol. The antioxidant composition of the present invention, wherein the substance having oxidation resistance may be selected from the group consisting of a ketone (such as a citrus fruit, a berry, a ginkgo leaf, an onion or a dark chocolate), and a cockroach (jnd〇丨es). , stone carotene (cold-Carotene, such as: palm oil, mango, cantaloupe or bok, etc.), genistein, anthocyanidin, LyCopene, red One to several of the above substances such as radish, watermelon or papaya, vitamin E, grape seed oil, L-vitamin c, and a substance having a stupid ring or a double bond structure. The antioxidant composition of the present invention, wherein the substance capable of grasping free radicals may be selected from the group consisting of sorghum, muscle (including Imidazole ring), containing histidine (Histidine), tyrosine (tyrosine), tryptophan One or several of the above-mentioned peptides or protein sequences of (Tryptophan), substances containing imidaz〇le ring, and stupid ring structure. The antioxidant composition of the present invention, wherein the substance having metal chelation ability may be selected from EDTA (ethylenediaminetetraacetic acid) 'citric acid, gluconic acid, or tartaric acid (dextrorotatory L-tartaric acid, L-L-tartaric acid, internal elimination) One to several of the above-mentioned tartaric acid. The antioxidant composition of the present invention, wherein the active powder has a weight percentage (%.w/w) of 15% to 70%; and the weight percentage (%.w/w) of the solvent is 30% to 85%; 5%。 The percentage by weight of the selective addition (%. w / w) is 0. 1%~0. 5%. 1011023#^ A0101 Page 6 of 12 1012004348-0 201244748 The antioxidant composition of the present invention, which may further comprise a whitening component selected from the group consisting of hydroquinone, citric acid, arbutin, azalea, etc. And at least one of the above; further comprising an anti-wrinkle component selected from the group consisting of at least one of fruit acid, vitamin A, vitamin B3, etc.; further comprising a moisturizing component selected from the group consisting of hyaluronic acid and an amine group At least one of the above, such as acid, glycerin or the like. The antioxidant composition of the present invention, wherein the antibacterial component is further selected from the group consisting of coconut oil, tea tree oil, natural citrus, citric acid, plant glycoside, and guava leaf; at least one of the above; The ingredients are selected from the group consisting of rosemary extract, perilla extract, melissa extract, aloe vera, ginseng extract, ginkgo extract, witch hazel extract, hydrolyzed wheat protein, calendula ingest, avocado oil, lotus Jojo oil, hawthorn containing yellow _ derivative, cyanine pigment, white cyanine derivative, triterpenic acid, saponin, tannin, hydrocarbyl benzoate, fatty acid, apricot kernel oil, azelaic acid, borage oil, At least one of triglyceride S, borage oil, hydrogenated soybean glyceride, lactic acid, linoleic acid, vitamin K, and vitamin A palmitate; further comprising an anti-corrosive component selected from the group consisting of At least one of eucalyptus oil, titanium ore, and monoisopropanolamine; and further comprising a whitening component selected from at least one of hydroquinone, citric acid, arbutin, and rhododendron. The above description is only intended to explain the present invention in detail by the preferred embodiments, however, any modifications and variations to the examples, such as active powder, solvent type and weight percentage, or application of the antioxidant composition of the present invention. Variations and the like do not depart from the spirit and scope of the invention. From the above detailed description, those skilled in the art can understand that the present invention can achieve the foregoing objectives, and has been in compliance with the provisions of the Patent Law. 1 {) 11 () 239 # single number A0101 page 7 / total 12 pages 1012004348-0 201244748 Invention patent application. [Simple diagram description] [0005] [Main component symbol description] [0006] Single number A0101 Page 8 of 12 1012004348-0