TW201236567A

TW201236567A - Pesticidal composition and method for controlling pests

Info

Publication number: TW201236567A
Application number: TW100142731A
Authority: TW
Inventors: Masayo Sugano
Original assignee: Sumitomo Chemical Co
Priority date: 2010-11-30
Filing date: 2011-11-22
Publication date: 2012-09-16
Also published as: AU2011250706A1; MX2011012767A; RU2011148622A; CN102475088A; JP2012131778A; BRPI1106999A2; TR201111810A2; AR083999A1

Abstract

A pesticidal composition comprising the ester compound represented by formula (I): and the ester compound represented by formula (II): as active ingredients, which has an excellent controlling effect on pests.

Description

201236567 六、發明說明：【發明所屬之技術領域】本發明申請案係經提出以主張日本專利申請案第 2010-266205號之優先權（在2010年11月30日提出），將其整個內容倂入本文以供參考。本發明係關於一種有害生物防制組成物及有害生物之防制方法。【先前技術】以式（I )代表的酯化合物： Η3σ〇Η2〇201236567 VI. Description of the Invention: [Technical Field to Which the Invention Is Applicable] The present invention has been filed with the priority of Japanese Patent Application No. 2010-266205 (filed on November 30, 2010), the entire contents of which are incorporated herein by reference. This article is incorporated by reference. The present invention relates to a pest control composition and a method for controlling pests. [Prior Art] An ester compound represented by the formula (I): Η3σ〇Η2〇

已知爲有害生物防制劑（例如，ΕΡ0054360Α2及 CN 1 0 1 306997A )。 Ο) EP0054360A2揭示式（I)化合物：It is known as a pest control agent (for example, ΕΡ0054360Α2 and CN 1 0 1 306997A). Ο) EP0054360A2 reveals a compound of formula (I):

其中R1及R2爲甲基、鹵甲基或鹵基，X爲0、S、S(0) 、S02或NR4，其中R4爲Η、低碳烷基或低碳羧酸系醯基，R3爲低碳烷基、低碳烯基、苯基或苯甲基，且另外R3 可在X爲NR4時爲Η ;及η爲1至4，以及用作爲殺蟲劑的包含該等化合物之組成物。 201236567 CN 1 0 1 3 06997A揭示一種具有如式A之結構的除蟲菊酯化合物=Wherein R1 and R2 are methyl, halomethyl or halo, and X is 0, S, S(0), S02 or NR4, wherein R4 is fluorene, lower alkyl or lower carboxylic acid fluorenyl, R3 is a lower alkyl group, a lower alkenyl group, a phenyl group or a benzyl group, and further R3 may be hydrazine when X is NR4; and η is 1 to 4, and a composition comprising the same as an insecticide . 201236567 CN 1 0 1 3 06997A discloses a pyrethroid compound having the structure of formula A =

在式A中，化合物爲右旋單旋光化合物，其中1^|及R2各自爲相同的鹵素或不同的鹵素。以式（11 )代表的酯化合物亦已知爲有害生物防制劑之活性成分（例如，GB1448228):In formula A, the compound is a right-handed mono-rotation compound wherein 1^| and R2 are each the same halogen or a different halogen. The ester compound represented by the formula (11) is also known as an active ingredient of a pest control preparation (for example, GB1448228):

GB 1 44822 8揭示以下通式之酯：GB 1 44822 8 discloses esters of the following general formula:

其中R1代表氫或甲基；R2代表氫或鹵基或烷基；R3代表氫或鹵基、烷基（當R2代表烷基時，其不同於R2)或羰烷氧基（當R2代表甲基時，其含有至少2個碳原子於烷氧基殘基中）’或R2及R3與彼等連接的碳原子—起代表具有至少一個內環碳至碳雙鍵的環伸烷基環；其先決條件係（a ) R2及R3僅在R1代表甲基時各代表氫及（b ) R3 -6- 201236567 在R1及R2各代表氫時含有至少2個碳原子：及R代表（ a)氫（或酸之鹽或酸鹵化物衍生物）或烷基，或（b)下式之基團：Wherein R1 represents hydrogen or methyl; R2 represents hydrogen or halo or alkyl; R3 represents hydrogen or halo, alkyl (when R2 represents alkyl, which is different from R2) or carbonylalkoxy (when R2 represents A) a radical, which contains at least 2 carbon atoms in the alkoxy residue) or a carbon atom to which R2 and R3 are bonded to each other, represents a cycloalkylene ring having at least one inner ring carbon to carbon double bond; The prerequisites are: (a) R2 and R3 each represent hydrogen only when R1 represents a methyl group and (b) R3 -6- 201236567 contains at least 2 carbon atoms when R1 and R2 each represent hydrogen: and R represents (a) Hydrogen (or acid salt or acid halide derivative) or alkyl group, or (b) a group of the formula:

然而，有需要在某些情況中提供具有較大的防制效果之有害生物防制劑，其係取決於該等劑之使用情況及由該等劑防制之有害生物而定。【發明內容】本發明的目的係提供一種對有害生物具有極佳的防制效果之有害生物防制組成物及有害生物之防制方法。本發明者密集地硏究且發現對有害生物極佳的防制效果係藉由伴隨使用以式（I)代表的酯化合物及以式（II )代表的酯化合物而獲得。據此完成本發明。本發明係關於下列者： [1 ] 一種有害生物防制組成物，其包含以式（I)代表的酯化合物：However, there is a need to provide a pest control agent having a large control effect in some cases, depending on the use of the agents and the pests prevented by the agents. SUMMARY OF THE INVENTION An object of the present invention is to provide a pest control composition and a pest control method which have an excellent control effect against harmful organisms. The present inventors have intensively studied and found that an excellent control effect against harmful organisms is obtained by concomitant use of an ester compound represented by the formula (I) and an ester compound represented by the formula (II). The present invention has thus been completed. The present invention relates to the following: [1] A pest control composition comprising an ester compound represented by the formula (I):

201236567 (以下稱爲"酯化合物A 〃）及以式（II )代物：201236567 (hereinafter referred to as "ester compound A 〃 ) and the formula (II ):

(以下稱爲'''酯化合物B ")作爲活性成分（本發明的有害生物防制組成物〃）。 [2] 根據上述[1]之組成物，其中酯化合衫合物B之重量比係從50 : 1至1 : 50。 [3] 一種有害生物之防制方法’其包含將與酯化合物B之合計有效量施予有害生物或有的棲息地。 [4] 一種酯化合物A與酯化合物B之組其係用於防制有害生物。本發明的效果有害生物防制組成物對有害生物具有極佳進行本發明的方式有害生物防制組成物係以含有酯化合物物B爲特徵。酯化合物A可藉由例如在EPO〇54360A2 法生產袠的酯化合 (Π) 以下稱爲'^ 'A對酯化醋化合物A 害生物棲息合的用途，的防制效果 ~及酯化合中所述之方 -8 - 201236567 酯化合物B可藉由例如在GB 1448228中所述之方法生產。酯化合物A及酯化合物B可形成異構物，因爲該等化合物各自具有兩個不對稱碳原子於環丙烷環上。在本發明中，含有以任何比値之此等活性異構物的化合物可用作爲酯化合物A或酯化合物B。以有害生物防制組成物對其具有效果的有害生物包括有害的節肢動物，諸如有害的昆蟲及有害的蜱蟎目（ acarina)。其具體實例係如下：鱗翅目（Lepidoptera):螺蛾科（Pyralidae)，諸如二化螟蛾（Chilo suppressalis )、稻縱捲葉野螟蛾（ Cnaphalocrocis medinalis )和印度穀粉螺蛾（Plodia interpunctella );夜蛾科（Noctuidae)，諸如斜紋夜蛾 (Spodoptera litura )、東方黏蟲（P s e u d a 1 e t i a s ep ar a t e ) 和甘藍夜蛾（Mamestra brassicae);粉蝶科（Pieridae) ，諸如紋白蝶（Pieris rapae crucivora);捲蛾科（ T ortricidae )，諸如姬捲葉蛾屬（Adoxophyes spp·):果蛀蛾科（Carposinidae);潛蛾科（Lyonetiidae):毒蛾科（Lymantriidae);苜蓿夜蛾（Autographa);地老虎屬（Agrotis spp.)，諸如黃地老虎（Agrotis segetum)和小地老虎（Agrotis ipsilon);葉蛾屬（Helicoverpa spp. );棉鈴蟲屬（Heliothis spp.);小菜蛾（Plutella xylostella );單帶弄蝶（P arnara guttata );袋衣蛾（ Tinea pellionella):衣蛾（Ti n eo 1 a b i s s el 1 i el 1 a )等。 201236567 雙翅目（Diptera):家蚊屬（Culex spp.)，諸如淡色庫蚊（Culex pipiens pallens )、三斑家蚊（Culex tritaeniorhynchus )和致倦庫蚊（Culex quinquefasciatus );斑蚊屬（Aedes spp.)，諸如埃及斑蚊（Aedes aegypti )和白線斑蚊（Aedes albopictus );按蚊屬（ Anopheles spp. ) ’ I者如中華瘡蚊（Anopheles sinensis) ;搖蚊科（Chironomidae);家蠅科（Muscidae)，諸如家蠅（Musca domestica)、秋家蠅（Musca corvina)、廢腐蠅（Muscina stabulans )和黃腹廢蠅（Fanrlia canicularis ):麗蠅科（Cal 1 iphordiae );麻蠅科（ Sarcophagidae );花蠅科（A n tho m y i i d a e )，諸如灰地種蠅（Delia platura)和蔥蠅（Delia antiqa);黑蠅科（ Sepidae):果實蠅科（Tephritidae);潛蠅科（ Agromyzidae );果蠅科（Drosophilidae)，諸如野生果蠅（Drosophila melanogaster);蛾蚋科（pSyCh〇didae) ，蛋繩科（Phoridae) ’諸如東亞異蛋繩（Megasalia spiracularis);蚋科（Simuliidae);虫亡科（Tabanidae) ;螫蠅科（Stomoxyidae);蠓科（Ceratopogonidae)等〇蛮赚目（Blattaria):德國斐嫌（Blattellagermanica )、黑胸大蠊（Periplaneta fuliginosa)、美洲蟹蠊（ P e r i p 1 a n e t a a m e r i c a n a )、掠色璧嫌（p e r i p 1 a n e t a b r u η n e a )、東方蛮蠊（B 1 a 11 a o r i e n t a 1 i s )等。膜翅目（Hymenoptera):蟻科（Formicidae)、胡 -10- 201236567 蜂科（Vespidae)、腫腿蜂科（Bethylidae)、葉蜂科（ T enthredini dae ) ’諸如紅角菜葉蜂（Athalia rosae ruficornis )等 ° 隱翅目（S i p h ο n a p t e r a ):犬蛋（Ctenocephalides canis )、猫香（Ctenocephalides felis )、人蚤（Pulex irritans )等。 1¾ 目（Anoplura):人益（Pediculus humanus)、陰 ^ ( Pthirus pubis)、頭蟲（P e d i c u 1 u s h u m anu s c ap i t i s ) 、人體蟲(Pediculus hum anu s corporis )等。等翅目（Isoptera):黃胸散白蟻（Reticulitermes speratus)、臺灣家白蟻（Coptot ermes formosanus )等 ° 半翅目（Hemiptera ) 飛蝨科（De 1 phaci dae )，諸如斑飛蝨（Laodelphax striatellus ) 、褐飛蟲((hereinafter referred to as '''ester compound B ") as an active ingredient (the pest control composition of the present invention). [2] The composition according to the above [1], wherein the weight ratio of the esterified compound B is from 50:1 to 1:50. [3] A pest control method which comprises administering a total effective amount of the ester compound B to a pest or a habitat. [4] A group of ester compound A and ester compound B which is used for the control of harmful organisms. EFFECTS OF THE INVENTION The pest control composition is excellent for pests. The present invention is characterized in that the pest control composition is characterized by containing an ester compound B. The ester compound A can be produced by, for example, the ester compound (Π) of the oxime produced by the method of EPO 〇 54360A2, hereinafter referred to as the use of the esterified vinegar compound A, and the control effect of the ester-incorporating compound. The formula -8 - 201236567 The ester compound B can be produced by the method described, for example, in GB 1448228. The ester compound A and the ester compound B can form an isomer because each of the compounds has two asymmetric carbon atoms on the cyclopropane ring. In the present invention, a compound containing such an active isomer in any ratio of hydrazine can be used as the ester compound A or the ester compound B. Pests that are effective against pest control compositions include harmful arthropods such as harmful insects and harmful acarina. Specific examples thereof are as follows: Lepidoptera: Pyralidae, such as Chilo suppressalis, Cnaphalocrocis medinalis, and Plodia interpunctella; Noctuidae, such as Spodoptera litura, P seuda 1 etias ep ar ate and Mamestra brassicae; Pieridae, such as Pieris rapae crucivora T ortricidae, such as Adoxophyes spp.: Carposinidae; Lyonetiidae: Lymantriidae; Autographa; (Agrotis spp.), such as Agrotis segetum and Agrotis ipsilon; Helicoverpa spp.; Heliothis spp.; Plutella xylostella; Parnara guttata; Tinea pellionella: Ti n eo 1 abiss el 1 i el 1 a and the like. 201236567 Diptera: Culex spp., such as Culex pipiens pallens, Culex tritaeniorhynchus and Culex quinquefasciatus; Aedes Spp.), such as Aedes aegypti and Aedes albopictus; Anopheles spp. 'I are such as Anopheles sinensis; Chironomidae; Musca domestica Muscidae, such as Musca domestica, Musca corvina, Muscina stabulans, and Fanrlia canicularis: Cal 1 iphordiae; Sarcophagidae ); Antho myiidae, such as Delia platura and Delia antiqa; Sepidae: Tephritidae; Agromyzidae Drosophilidae, such as Drosophila melanogaster; pSyCh〇didae, Phoridae 'such as Megasalia spiracularis; Simuliidae; Death (Ta Banidae); Stomoxyidae; Ceratopogonidae, etc. (Blattaria): Blattellagermanica, Periplaneta fuliginosa, Perip 1 anetaamericana, It is suspected of perip 1 anetabru η nea and B 1 a 11 aorienta 1 is. Hymenoptera: Formicidae, Hu-10-201236567 Vespidae, Bethylidae, T enthredini dae 'Athalia rosae Ruficornis ) et al ° Sipph ο naptera: Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, etc. Anoplura: Pediculus humanus, Pthirus pubis, P e d i c u 1 u s h u m anu s c ap i t i s, human worm (Pediculus hum anu s corporis), and the like. Isoptera: Reticulitermes speratus, Coptot ermes formosanus, etc. Hemiptera De 1 phaci dae, such as Laodelphax striatellus Brown fly (

Nilaparvata lugens)和白背飛蝨（Sogatella furcifera); 浮塵子科（Deltocephalidae )，諸如黑尾葉禪（ Nephotettix cincticeps)和二點黑尾葉蟬（Nephotettix virescens) ’ 极科（Aphididae);棒科（pentatomidae) ;粉蝨科（Aleyrodidae);軟介殼蟲科（coccidae);臭蟲科（Cimicidae) ’ 諸如溫帶臭蟲（cimex lectularius) ;軍配蟲科（Tingidae);木蝨科（psyilidae)等。鞘翅目（Coleoptera ) .·姬經節蟲（Attagenus unicolor);姬圓鏗節蟲（Anthrenus verbasci);玉米食根蟲（corn rootworms )，諸如玉米根蟲（Diabrotic virgifera)和十一星瓜葉甲（Diabrotica undecimpunctaca 201236567 howardi);金龜子科（Scarabaeidae)，諸如金銅金龜（ Anomala cuprea )和棒姬金龜(Anomala rufocuprea )；象鼻蟲科（Curculionidae)，諸如玉米象（Sitophilus zeamais)、稻象甲（Lissorhoptrus oryzophilus)、棉鈴象甲（Anthonomus grandis grandis )和綠豆象（ Callosobruchus chinensis )；擬步甲科(Tenebrionidae ) ，諸如黃粉蟲（Tenebrio molitor)和赤擬穀盜（ Tribolium castaneum):金花蟲科（Chrysomelidae)，諸如稻負泥蟲（Oulema oryzae )、黃條葉蚤（Phy 11 otreta striolata)和黃守瓜（Aulacophora femoralis);竊蟲科 (Anobiidae);瓢蟲屬（Epilachna spp_)，諸如茄二十八星瓢蟲（Henosepilachna vigintioctopunctata);粉蠹科（Lyctidae):長蟁蟲科（Bostrychidae);天牛科（ Cerambycidae);蟻型隱翅蟲（Paederus fuscipes)等。纓翅目（Thysanoptera):南黃薊馬（Thrips palmi) 、西方花薊馬（Frankliniella occidentalis)、花薊馬（Nilaparvata lugens) and Sogatella furcifera; Deltocephalidae, such as Nephotettix cincticeps and Nephotettix virescens 'Aphididae; pentatomidae ; Aleyrodidae; coccidae; Cimicidae 'such as temperate bed bug (cimex lectularius); Tingidae (Tingidae); psyilidae (psyilidae). Coleoptera. Attagenus unicolor; Anthrenus verbasci; corn rootworms, such as Diabrotic virgifera and eleven star melons (Diabrotica undecimpunctaca 201236567 howardi); Scarabaeidae, such as Anomala cuprea and Anomala rufocuprea; Curculionidae, such as Sitophilus zeamais, Lysorhoptrus Oryzophilus), Anthonomus grandis grandis and Callosobruchus chinensis; Tenebrionidae, such as Tenebrio molitor and Tribolium castaneum: Golden Flower ( Chrysomelidae), such as Oulema oryzae, Phy 11 otreta striolata and Aulacophora femoralis; Anobiidae; Epilachna spp_, such as Solanum 18-spotted ladybug (Henosepilachna vigintioctopunctata); Lyctidae: Bostrychidae; Cerambycidae ( Cerambycidae); Paederus fuscipes and the like. Thysanoptera: Thrips palmi, Frankliniella occidentalis, flower hummer

Thrips hawaiiensis)等。直翅目（Orthoptera ):螻蛄科（G ry 11 〇 t a 1 p i d ae )、煌科（Acrididae)等。蜱嫡目（Acarina):塵蟎科（Pyr〇giyphidae)，諸如美洲塵蟎（Dermatophago丨des farinae)和歐洲塵蟎（ Dermatophagoides pteronyssinus )；粉蟎科(Acaridae ) ’諸如腐食酪蟎（Tyrophagus putrescentiae)和橢圓嗜粉蟎（Aleuroglyphus ovatus);嗜甜蟎科（GlyCyPhagidae -12- 201236567 )’ π者如隱秘食甜蝶（Glycyphagus privatus)、嗜甜家蟎（Glycyphagus domesticus)和長鬚粉蟎（Glycyphagus destructor );肉食蟎科（cheyletidae )，諸如馬六甲肉食觸（Cheyletus malaccensis)和點肉食蝴（Cheyletus moorei) ’ 細觸科（Tarsonemidae):嗜草蟎科（ Chortoglyphidae ):地蟎（Oribatei );葉蟎科（ Tetranychidae) ’ 諸如二斑葉蟎（Tetranychus urticae) 、神澤葉蟎（Tetranychus kanzawai)、柑桔全爪摘（ Panonychus citri)和榆全爪觸（panonyChus ulmi);硬蜱科（Ixodidae )，諸如長角血蜱（Haemaphysalis longicornis);皮刺輸科（Dermanyssidae)，諸如禽刺鍋 (Ornithonyssus sylvairum )和雞皮刺織（Dermanyssus galinae )等。本發明的有害生物防制組成物特別對雙翅目具有極佳的防制效果。在本發明的有害生物防制組成物中的酯化合物A對酯化合物B之重量比通常從50 : 1至1 : 50，較佳爲從20 :1至1:20，更佳爲從2:1至1:20。雖然酯化合物A與酯化合物B之單純混合物可以其原樣子用作爲本發明的有害生物防制組成物，但是通常係在調配成以下調配物中之任一者之後施予。調配物包括油性調配物、可乳化濃縮物、可濕性粉末、可流動濃縮物（例如，水性懸浮液濃縮物和水性乳液濃縮物）、微膠囊、粉劑、顆粒、錠劑 '氣霧劑、二氧化碳調配物、以加熱之 -13- 201236567 揮發性調配物（例如、殺蟲圈、用於電力口吸收芯加熱之揮發性調配物）、壓電型殺式燻蒸劑（例如，自燃型燻蒸劑、化學反孔陶瓷板燻蒸劑）、非加熱式揮發性調配揮發性調配物、紙製揮發性調配物、不織、編織品揮發性調配物和昇華錠）、煙燻，煙霧劑）、直接接觸式調配物（例如，配物、似帶狀接觸式調配物和似網狀接 ULV調配物及毒餌。可舉例以下的方法作爲調配方法。 (1) 其中將酯化合物A及酯化合物液體載劑、氣體載劑、誘餌或類似物混合要時，將界面活性劑及/或用於調配的其其中，接著加工。 (2) 其中將基底材料以酯化合物A 漬之方法。 (3) 其中將酯化合物A、酯化合物合且接著模製或定型。此一調配物含有通常爲0.001至98 酯化合物A及酯化合物B，雖然該總量係型而定。用於調配物的固體載劑包括黏土的細如，高嶺土、矽藻土、膨潤土、富巴沙（和酸性白黏土）、合成性水合二氧化矽、熱之殺蟲片和以蟲調配物、加熱應型燻蒸劑和多物（例如，樹脂布揮發性調配物式調配物（例如似片狀接觸式調觸式調配物）、 B與固體載劑、之方法，且若必他輔助劑添加至及酯化合物B浸 B與基底材料混重量％之總量的取決於調配物類粉末及顆粒（例 fubasami )黏土滑石、陶瓷、其 -14- 201236567 他的無機礦物（例如，絹雲母、石英、硫、活性碳、碳酸銘和水合砂石）和化學肥料（例如，硫酸銨、磷酸銨、硝酸銨、氯化銨和尿素）；在常溫下爲固體之物質（例如， 2,4,6-三異丙基·1，3,5-三噁烷、萘、對_二氯苯、樟腦和金剛石）；及Κ製品、纖維、布料、織物 '薄片、紙、紗線、泡沫、多孔性材料和下列材料中之一或多者之複絲：羊毛、絲、棉、麻、紙漿、合成樹脂（例如，聚乙烯樹脂，諸如低密度聚乙烯、直鏈低密度聚乙烯和高密度聚乙烯；乙燃-乙燦酯共聚物’諸如乙稀-乙酸乙嫌酯共聚物；乙烯-甲基丙烯酸酯共聚物’諸如乙烯-甲基丙烯酸甲酯共聚物和乙烯-甲基丙烯酸乙酯共聚物；乙烯-丙烯酸酯共聚物 ’諸如乙烯-丙烯酸甲酯共聚物和乙烯-丙烯酸乙酯共聚物 •，乙烯·乙烯基羧酸共聚物，諸如乙烯-丙烯酸共聚物；乙稀-四環十二碳稀共聚物；聚丙燒樹脂，諸如丙烯均聚物和丙嫌-乙烧共聚物’·聚-4-甲基戊燦_1、聚丁稀、聚丁二烯和聚苯乙烯；丙烯腈-苯乙烯樹脂；以苯乙烯爲底質之彈性體’諸如丙烯腈-丁二烯-苯乙烯樹脂、苯乙烯-共軛二烯嵌段共聚物和苯乙烯·共軛二烯嵌段共聚物氫化產物；氟樹脂；丙嫌酸系樹脂，諸如聚（甲基丙嫌酸甲醋） :聚醯胺樹脂，諸如耐綸6和耐輪66 ;聚醋樹脂，諸如聚（對苯二甲酸乙二酯）、聚（萘二甲酸乙二醋）、聚（對苯二甲酸丁二酯）和聚（對苯二甲酸伸環己基二亞甲酯 ):及多孔性樹脂’諸如聚碳酸酯、聚縮醛、聚丙烯颯、聚芳香酯（polyarylate)、羥基苯甲酸聚酯、聚醚醯亞胺 -15- 201236567 、聚酯碳酸酯'聚苯醚樹脂、聚（氯乙烯）、聚（偏二氯乙烯）、聚胺基甲酸酯、膨脹之聚胺基甲酸酯、膨脹之聚丙烯和膨脹之聚乙烯）、玻璃、金屬、陶瓷及類似物。液體載劑包含芳香族或脂族烴（例如，二甲苯、甲苯、烷基萘、苯基二甲苯基乙烷、煤油、輕油、己烷和環己烷）、鹵化烴（例如，氯苯、二氯甲烷、二氯乙烷和三氯乙烷）、醇（例如，甲醇、乙醇、異丙醇、丁醇、己醇、苯甲醇和乙二醇）、醚（例如，二乙醚、乙二醇二甲醚、二乙二醇單甲醚、二乙二醇單乙醚、丙二醇單甲醚、四氫呋喃和二噁烷）、酯（例如，乙酸乙酯和乙酸丁酯）、酮 (例如，丙酮、甲基乙酮、甲基異丁酮和環己酮）、腈（例如’乙腈和異丁腈）、亞楓（例如，二甲亞颯）、酸醯胺（例如，N，N-二甲基甲醯胺、Ν,Ν·二甲基乙醯胺和Ν-甲基吡咯啶酮）、碳酸伸烷酯（例如，碳酸伸丙酯）、植物油（例如，大豆油和棉籽油）、植物精油（例如，橙油、喜壽花油和檸檬油）及水。氣體載劑包含丁烷氣體、CFC氣體、液化石油氣（ LPG)、二甲醚及二氧化碳。界面活性劑包含烷基硫酸鹽、烷基磺酸鹽、烷基芳基磺酸鹽、烷基芳基醚和彼之聚氧乙烯化產物、聚乙二醇醚、多元醇酯及糖醇衍生物。用於調配的其他輔助劑包括黏著劑、分散劑及安定劑。其具體實例爲酪蛋白、明膠、多醣類（例如，澱粉、阿拉伯膠 '纖維素衍生物和藻酸）、木質素衍生物、膨潤土 •16- 201236567 、醣類、合成水溶性聚合物[例如，聚（乙烯醇）、聚（乙烯基吡咯啶酮）和聚丙烯酸]、ΒΗΤ(2,6-二-第三丁基· 4-甲酚）、BHA( 2-第三丁基-4-甲氧酚與3-第三丁基-4- 甲氧酚之混合物）等。用於殺蟲圈的基底材料包括未加工之植物粉末（例如，木粉和除蟲菊渣）與黏合劑（例如，Tabu粉末、澱粉和麩質）之混合物。用於電加熱之殺蟲片的基底材料包括棉絨的經壓實之原纖維平板及棉絨與紙漿之混合物的經壓實之原纖維平板〇自燃型燻蒸劑的基底材料包括燃燒放熱劑（例如，硝酸鹽、亞硝酸鹽、胍鹽、氯酸鉀、硝基纖維素、乙基纖維素和木粉）；熱分解促進劑（例如，鹼金屬鹽、鹼土金屬鹽、重鉻酸鹽和鉻酸鹽）：氧供給劑（例如，硝酸鉀）；燃燒助劑（例如’三聚氰胺和小麥澱粉）；伸展劑（例如 ’矽藻土）：及黏合劑（例如，合成糊劑）。用於化學反應型燻蒸劑的基底材料包括放熱劑（例如 ’鹼金屬之硫化物、多硫化物和硫氫化物，和氧化鈣）；催化劑（例如，碳質物質、碳化鐵和活性黏土）；有機發泡劑（例如，偶氮二甲醯胺、苯磺醯肼、二硝基五亞甲基四胺、聚苯乙烯和聚胺基甲酸酯）·，及塡充劑（例如，天然纖維片和合成纖維片）。用作爲樹脂揮發性調配物及類似物的基底材料之樹脂包含聚乙嫌樹脂’諸如低密度聚乙烯、直鏈低密度聚乙烯 -17- 201236567 和高密度聚乙烯：乙烯-乙烯酯共聚物，諸如乙烯-烯酯共聚物；乙烯·甲基丙烯酸酯共聚物，諸如乙犬丙烯酸甲酯共聚物和乙烯-甲基丙烯酸乙酯共聚物丙烯酸酯共聚物，諸如乙烯-丙烯酸甲酯共聚物和z 烯酸乙酯共聚物；乙烯·乙烯基羧酸共聚物，諸如z 烯酸共聚物；乙烯-四環十二碳烯共聚物；聚丙烯諸如丙烯均聚物和丙烯-乙烯共聚物；聚-4-甲基戊聚丁烯-1、聚丁二烯、聚苯乙烯和丙烯腈-苯乙烯以苯乙烯爲底質之彈性體，諸如丙烯腈-丁二烯-苯脂、苯乙烯-共軛二烯共聚物和苯乙烯-共軛二烯嵌物氫化產物：氟樹脂；丙烯酸系樹脂，諸如聚（甲酸甲酯）：聚醯胺樹脂，諸如耐綸6和耐綸66 : 脂，諸如聚（對苯二甲酸乙二酯）、聚（萘二甲酸 )、聚（對苯二甲酸丁二酯）和聚（對苯二甲酸伸二亞甲酯）；及聚碳酸酯、聚縮醛、聚丙烯颯、聚酯、羥基苯甲酸聚酯、聚醚醯亞胺、聚酯碳酸酯、樹脂、聚（氯乙烯）、聚（偏二氯乙烯）和聚胺基。該等基底材料可單獨使用或以其混合物使用。若，該等基底材料可含有塑化劑，諸如苯二甲酸酯（苯二甲酸二甲酯和苯二甲酸二辛酯）、己二酸酯及。樹脂揮發性調配物的獲得可藉由將酯化合物A 合物B與上述舉例之基底材料揉合，且接著將揉合藉由射出模製、擠壓、壓縮或類似方式而模製或定必要時，可將所獲得的樹脂調配物經由諸如模製或乙酸乙希-甲基 ;乙烯· 烯-丙 L烯-丙樹脂，烯-1、樹脂；乙烯樹段共聚基丙烯聚酯樹乙二酯環己基丙烯酸聚苯醚甲酸酯必要時例如，硬酯酸及酯化之產物型。若定型、 -18- 201236567 切割及類似之步驟加工成平板、膜、帶狀物、網狀物、細繩或類似物。將此一樹脂調配物加工成例如動物頸圈、動物耳標、薄片調配物、誘引繩及園藝樁柱（horticultural stays ) 〇用於毒ϋ的基底材料包括誘餌組份（例如，穀粉、植物油'醣類和結晶纖維素）：抗氧化劑（例如，二丁基羥基甲本和降一氮癒創木酸（nordihydroguaiaretic acid)) ;防腐劑（例如’去氫乙酸）；防兒童或寵物誤食劑（例如’辣椒粉）：及誘引昆蟲-有害生物之香料（例如，乳酪香料、洋蔥香料和花生油）。在本發明的方法中，有害生物係藉由將本發明的有害生物防制組成物施予有害生物或有害生物棲息的棲息地（植物、土壤、室內、動物等）而予以防制。另外，有害生物係藉由將酯化合物A及酯化合物B的合計有效量個別施予有害生物或有害生物棲息的棲息地而予以防制。Thrips hawaiiensis) and so on. Orthoptera: G ry 11 〇 t a 1 p i d ae , Acrididae, etc. Acarina: Pyr〇giyphidae, such as Dermatophago丨des farinae and Dermatophagoides pteronyssinus; Acaridae' such as Tyrophagus putrescentiae And Aleuroglyphus ovatus; GlyCyPhagidae -12- 201236567 ' π such as Glycyphagus privatus, Glycyphagus domesticus and Glycyphagus destructor ); cheyletidae, such as the genus Cheyletus malaccensis and Cheyletus moorei 'Tarsonemidae: Chortoglyphidae: Oribatei; (Tetranychidae) 'such as Tetranychus urticae, Tetranychus kanzawai, Panonychus citri and panonyChus ulmi; Ixodidae, such as Haemaphysalis longicornis; Dermanyssidae, such as Ornithonyssus sylvairum and chicken prickles (Dermanyssus galinae) and so on. The pest control composition of the present invention has an excellent control effect particularly on Diptera. The weight ratio of the ester compound A to the ester compound B in the pesticidal composition of the present invention is usually from 50:1 to 1:50, preferably from 20:1 to 1:20, more preferably from 2: 1 to 1:20. Although a simple mixture of the ester compound A and the ester compound B can be used as it is as the pest control composition of the present invention, it is usually administered after being formulated into any of the following formulations. Formulations include oily formulations, emulsifiable concentrates, wettable powders, flowable concentrates (eg, aqueous suspension concentrates and aqueous emulsion concentrates), microcapsules, powders, granules, lozenges 'aerosols, Carbon dioxide formulation, heated-13-201236567 Volatile formulation (eg, insecticidal ring, volatile formulation for power port absorption core heating), piezoelectric killer fumigant (eg, self-igniting fumigant) , chemical anti-porous ceramic plate fumigant), non-heated volatile blending volatile formulation, paper volatile formulation, non-woven, woven volatiles and sublimation ingots, smoked, aerosol), direct Contact formulations (for example, ligands, ribbon-like contact formulations, and mesh-like ULV formulations and poison baits. The following methods can be exemplified as the formulation method. (1) In which the ester compound A and the ester compound are liquid-loaded. When the agent, gas carrier, bait or the like is mixed, the surfactant and/or the compound for the preparation thereof are then processed. (2) wherein the base material is stained with the ester compound A (3) wherein the ester compound A, the ester compound is combined and then molded or shaped. The formulation contains usually from 0.001 to 98 ester compound A and ester compound B, although the total amount depends on the formulation. The solid carrier of the material includes fine clay, kaolin, diatomaceous earth, bentonite, fubasta (and acid white clay), synthetic hydrated cerium oxide, hot insecticide and insect compound, heating type Fumigants and multi-materials (for example, a resin cloth volatile formulation formulation (such as a sheet-like contact tactile formulation), B and a solid carrier, and if the adjuvant is added to the ester The total amount of compound B immersed in B and the base material is determined by the formulation of powders and granules (eg, fubasami) clay talc, ceramics, and its inorganic minerals (eg, sericite, quartz, sulfur, Activated carbon, carbonated and hydrated sandstone) and chemical fertilizers (for example, ammonium sulfate, ammonium phosphate, ammonium nitrate, ammonium chloride and urea); substances that are solid at room temperature (for example, 2, 4, 6-three different) Propyl·1,3,5- Oxane, naphthalene, p-dichlorobenzene, camphor and diamond); and multifilaments of one or more of tantalum products, fibers, fabrics, fabrics, sheets, paper, yarns, foams, porous materials and the following materials : wool, silk, cotton, hemp, pulp, synthetic resin (for example, polyethylene resin, such as low density polyethylene, linear low density polyethylene and high density polyethylene; ethylene-ethylene ester copolymer) such as ethylene - Ethyl acetate copolymer; ethylene-methacrylate copolymer such as ethylene-methyl methacrylate copolymer and ethylene-ethyl methacrylate copolymer; ethylene-acrylate copolymer such as ethylene-acrylic acid Ester copolymer and ethylene-ethyl acrylate copolymer, ethylene/vinyl carboxylic acid copolymer, such as ethylene-acrylic acid copolymer; ethylene-tetracyclododecane copolymer; polypropylene resin, such as propylene homopolymer And C-supplement-Ethylene-sinter copolymer'·Poly-4-methylpentan-1, polybutylene, polybutadiene and polystyrene; acrylonitrile-styrene resin; styrene-based elastomer 'such as acrylonitrile-butadiene-styrene resin a styrene-conjugated diene block copolymer and a hydrogenated product of a styrene-conjugated diene block copolymer; a fluororesin; a acrylic acid such as poly(methyl propyl ketone): polydecylamine Resins such as nylon 6 and liner 66; polyester resins such as poly(ethylene terephthalate), poly(ethylene naphthalate), poly(butylene terephthalate) and poly( Terephthalic acid cyclohexyl dimethylene methyl ester): and porous resin 'such as polycarbonate, polyacetal, polypropylene fluorene, polyarylate, hydroxybenzoic acid polyester, polyether quinone imine - 15- 201236567 , Polyester carbonate 'polyphenylene ether resin, poly(vinyl chloride), poly(vinylidene chloride), polyurethane, expanded polyurethane, expanded polypropylene and expanded Polyethylene), glass, metal, ceramics and the like. Liquid carriers include aromatic or aliphatic hydrocarbons (eg, xylene, toluene, alkylnaphthalene, phenyldimethylphenylethane, kerosene, light oil, hexane, and cyclohexane), halogenated hydrocarbons (eg, chlorobenzene) , dichloromethane, dichloroethane and trichloroethane), alcohols (eg methanol, ethanol, isopropanol, butanol, hexanol, benzyl alcohol and ethylene glycol), ethers (eg diethyl ether, B) Diol dimethyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, propylene glycol monomethyl ether, tetrahydrofuran and dioxane), esters (for example, ethyl acetate and butyl acetate), ketones (for example, Acetone, methyl ethyl ketone, methyl isobutyl ketone and cyclohexanone), nitriles (such as 'acetonitrile and isobutyronitrile), argon (for example, dimethyl hydrazine), acid amide (for example, N, N- Dimethylformamide, hydrazine, hydrazine dimethylacetamide and hydrazine-methylpyrrolidone), alkylene carbonate (for example, propyl carbonate), vegetable oil (for example, soybean oil and cottonseed oil) , plant essential oils (for example, orange oil, celery oil and lemon oil) and water. The gaseous carrier comprises butane gas, CFC gas, liquefied petroleum gas (LPG), dimethyl ether and carbon dioxide. The surfactant comprises an alkyl sulfate, an alkyl sulfonate, an alkyl aryl sulfonate, an alkyl aryl ether and a polyoxyethylated product thereof, a polyethylene glycol ether, a polyol ester, and a sugar alcohol derivative. Things. Other adjuvants for formulation include adhesives, dispersants, and stabilizers. Specific examples thereof are casein, gelatin, polysaccharides (for example, starch, gum arabic 'cellulose derivatives and alginic acid), lignin derivatives, bentonite•16-201236567, sugars, synthetic water-soluble polymers [eg , poly(vinyl alcohol), poly(vinylpyrrolidone) and polyacrylic acid], hydrazine (2,6-di-t-butyl-4-methylphenol), BHA (2-tert-butyl-4- a mixture of methoxyphenol and 3-tert-butyl-4-methoxyphenol) and the like. Substrate materials for the insecticidal ring include a mixture of unprocessed plant powders (e.g., wood flour and pyrethrum) and binders (e.g., Tabu powder, starch, and gluten). The base material for the electrically heated insecticidal sheet comprises a compacted fibril plate of cotton linters and a compacted fibril plate of a mixture of lint and pulp. The base material of the pyrophoric fumigant comprises a combustion exothermic agent ( For example, nitrates, nitrites, phosphonium salts, potassium chlorate, nitrocellulose, ethyl cellulose, and wood flour); thermal decomposition promoters (for example, alkali metal salts, alkaline earth metal salts, dichromates, and chromic acid) Salt): oxygen donor (eg, potassium nitrate); combustion aids (eg, 'melamine and wheat starch'); extenders (eg, 'diatomaceous earth'): and binders (eg, synthetic pastes). Substrate materials for chemically reactive fumigants include exothermic agents (eg, 'alkali metal sulfides, polysulfides and hydrosulfides, and calcium oxides); catalysts (eg, carbonaceous materials, iron carbide, and activated clay); Organic blowing agents (eg, azomethoxamine, benzenesulfonamide, dinitropentamethylenetetramine, polystyrene, and polyurethane), and chelating agents (eg, natural Fiber sheets and synthetic fiber sheets). The resin used as the base material of the resin volatile formulation and the like comprises a polyethylene-like resin such as low density polyethylene, linear low density polyethylene-17-201236567 and high density polyethylene: ethylene-vinyl ester copolymer, Such as ethylene-ene ester copolymer; ethylene·methacrylate copolymer, such as ethyl canton methacrylate copolymer and ethylene-ethyl methacrylate copolymer acrylate copolymer, such as ethylene-methyl acrylate copolymer and z Ethyl acrylate copolymer; ethylene vinyl carboxylic acid copolymer, such as zenoic acid copolymer; ethylene-tetracyclododecene copolymer; polypropylene such as propylene homopolymer and propylene-ethylene copolymer; poly- 4-methylpentamrene-1, polybutadiene, polystyrene and acrylonitrile-styrene styrene-based elastomers such as acrylonitrile-butadiene-phenylene, styrene-total A conjugated diene copolymer and a styrene-conjugated diene inlaid hydrogenated product: a fluororesin; an acrylic resin such as poly(methyl formate): a polyamide resin such as nylon 6 and nylon 66: a grease such as Poly(ethylene terephthalate), poly( Naphthalene dicarboxylic acid), poly(butylene terephthalate) and poly(methylene terephthalate); and polycarbonate, polyacetal, polypropylene oxime, polyester, hydroxybenzoic acid polyester, Polyetherimine, polyester carbonate, resin, poly(vinyl chloride), poly(vinylidene chloride) and polyamine. The base materials may be used singly or in a mixture thereof. If such base materials may contain plasticizers such as phthalate (dimethyl phthalate and dioctyl phthalate), adipates and . The resin volatile formulation can be obtained by kneading the ester compound A compound B with the above-exemplified base material, and then molding the compound by extrusion molding, extrusion, compression or the like. At the time, the obtained resin formulation may be passed through, for example, molding or ethyl acetate-methyl; ethylene-ene-propylene-propylene resin, ene-1, resin; ethylene tree segment copolymerized propylene polyester tree The ester cyclohexyl acrylate polyphenylene ether carboxylate is, for example, a product of a stearic acid and an esterified product. If styling, -18-201236567 cutting and similar steps are processed into flat sheets, membranes, ribbons, meshes, strings or the like. The resin formulation is processed into, for example, animal collars, animal ear tags, flake formulations, attracting ropes, and horticultural stays. Base materials for the poisonous mites include bait components (eg, flour, vegetable oils). Carbohydrates and crystalline cellulose): antioxidants (eg, dibutylhydroxybenzamide and nordihydroguaiaretic acid); preservatives (eg 'dehydroacetic acid'); anti-child or pet ingestion (eg 'chili powder'): and attract insects - pests of spices (eg, cheese spices, onion flavors and peanut oil). In the method of the present invention, the harmful organism is prevented by administering the pest control composition of the present invention to a habitat (plant, soil, indoor, animal, etc.) in which the pest or the pest inhabits. Further, the harmful organism is prevented by individually applying the total effective amount of the ester compound A and the ester compound B to the habitat in which the pest or the pest inhabits.

本文的"合計有效量〃意謂酯化合物A與酯化合物B 的總量’其中兩種化合物的施予量可使有害生物受到防制〇用於施予本發明的有害生物防制組成物之方法的具體實例爲下列方法。施予方法可取決於本發明的有害生物防制組成物形式、施予位置等而適當地選擇。 (1 )其中將本發明的有害生物防制組成物本身施予有害生物或有害生物棲息的棲息地之方法。 (2 )其中將本發明的有害生物防制組成物以溶劑（ -19- 201236567 諸如水）稀釋及接著施予有害生物或有害生物棲息的棲息地之方法。在方法（2 )中，經常將調配成可乳化濃縮物、可濕性粉末、可流動濃縮物、微膠漢或類似物之本發明的有害生物防制組成物稀釋，使得酯化合物A及酯化合物B的總濃度可爲0.01至l，000ppm。 (3)其中將本發明的有害生物防制組成物在有害生物棲息的棲息地加熱之方法，使活性成分蒸發。在方法（3)中，酯化合物A及酯化合物B之施予劑量及施予濃度二者可取決於本發明的有害生物防制組成物形式，何時、何處和如何施予有害生物防制組成物，損傷程度等而適當地決定。當使用本發明的有害生物防制組成物來預防傳染病時，其在施予空間中之情況中的施予劑量係以酯化合物 A 及酯化合物B之總量而言通常爲0·0001至1，〇〇〇毫克/立方公尺，而在施予平面上之情況中的施予劑量係以酯化合物Α及酯化合物Β之總量而言通常爲0.0001至1，〇〇〇毫克/平方公尺。以加熱之揮發性調配物（諸如殺蟲圈和以電加熱之殺蟲片）係取決於此等調配物的類型而以加熱使活性成分揮發來使用。非加熱式揮發性調配物（諸如樹脂揮發性調配物、紙製揮發性調配物、不織布揮發性調配物、編織品揮發性調配物和昇華錠）可藉由例如允許該等調配物放置在施予彼等的空間中或對著該等調配物吹動空氣來使用。 -20- 201236567 以預防傳染病而施予本發明的有害生物防制組成物之空間包括壁櫥、壁櫃、衣櫃、餐具櫃、洗手間、浴室、堆藏室、起居室、餐廳、倉庫和汽車內部。另外，本發明的有害生物防制組成物亦可用於戶外開放空間。當使用本發明的有害生物防制組成物防制家畜（諸如牛、馬、豬、綿羊、山羊、雞等）及小型動物（諸如狗、貓、大鼠、小鼠等）的外寄生蟲時，可將其以獸醫學領域中熟知的方法施予動物。使用本發明的有害生物防制組成物之方法具體如下。用於全身性防制之有害生物防制組成物係以例如錠劑、與飼料的混合物、栓劑或注射劑（例如 ’肌肉內、皮下、靜脈內或腹膜內注射）形式投予。用於非全身性防制之有害生物防制組成物係以諸如以油性調配物或水性液體調配物噴灑、以油性調配物或水性液體調配物澆注（pour-on )或滴注（spot-on )處理、以洗髮精調配物洗滌動物、或以頸圈或耳標形式的樹脂揮發性調配物安裝於動物之方法來使用。當本發明的有害生物防制組成物投予動物時’酯化合物A及酯化合物b之總量通常係以每公斤動物體重計從0.01至1,〇〇〇毫克之範圍內。在本發明的有害生物防制組成物中，可將其他的有害生物防制劑（諸如殺昆蟲劑和殺觸劑、忌避劑、增效劑、顏料等）進一步與酯化合物A及酯化合物b混合或伴隨使用8 【實施方式】 • 21 - 201236567 實例本發明係以下列的調配物實例及試驗實例進一例證，不應將該等實例解釋爲限制本發明的範圍。首先舉例本發明的有害生物防制組成物之調配調配物實例及試驗實例中，份量皆以質量計，除非定。調配物實例1 將9份酯化合物A及0.9份酯化合物B溶解份二甲苯與37.5份N，N-二甲基甲醯胺之混合物 9.1份聚氧乙烯苯乙烯基苯醚及6份十二烷基苯磺加至其中，且將所得混合物充分攪拌及混合，獲得濃縮物。調配物實例2 將20份酯化合物A、20份酯化合物B與5份 5060 ( Toho Chemical Co., Ltd.之註冊商標）充份將 32 份 Carplex #80 (Shionogi & Co·，Ltd.之註冊合成性水合二氧化矽細粉末）及2 3份3 0 0篩目矽加至其中，且將所得混合物在果汁機中混合，獲得粉末。調配物實例3 將5份合成性水合二氧化矽細粉末、5份十二步詳細物。在另行指 £ 37.5 中，將酸鈣添可乳化 S orpo1 混合，商標；藻土添可濕性烷基苯 -22- 201236567 磺酸鈉、30份膨潤土及56_7份黏土添加至3份酯化合物 A與0.3份酯化合物B之混合物中’且將所得混合物充分攪拌及混合。然後將適當的水量添加至所得混合物中且進一步攪拌。使因此攪拌的混合物接受製粒機的粒徑調整及接著通風乾燥，獲得顆粒。調配物實例4 將5份酯化合物A、0.5份酯化合物B、1份合成性水合二氧化矽細粉末、作爲絮凝劑的1份Driless B (由 Sankyo Co., Ltd.所製造）與7份黏土在碾缽中充分混合，且接著在果汁機中攪拌及混合。將85.5份切削黏土（ c u t c 1 a y )添加至所得混合物中，且將所得混合物充分攪拌及混合，獲得粉劑。調配物實例5 將1 〇份酯化合物A、1份酯化合物B、3 5份含有5 0 %之聚氧乙烯烷基醚硫酸銨鹽的白碳與54份水混合，且將所得混合物以濕式硏磨法細硏磨，獲得粉劑。調配物實例6 將〇.〇5份酯化合物A及0.1份酯化合物B溶解在1〇份二氯甲烷中，且將所得溶液與8 9.8 5份異烷烴溶劑（ Isopar Μ ’ Exxon Chemical Co.之註冊商標）混合，獲得油性調配物。 -23- 201236567 調配物實例7 將0.1份酯化合物Α、0·05份酯化合物B及49.85份 Neochiozol ( Chuokasei Co·, Ltd.)放入氣霧罐中，將氣霧閥安裝至氣霧罐，將25份二甲醚及25份LPG裝入氣霧罐中，搖動氣霧罐且接著將引動器安裝至氣霧罐，獲得以油爲底質之氣霧劑。調配物實例8 將0.5份酯化合物A、0.05份酯化合物B、0.01份 BHT、5份二甲苯、3.44份脫臭煤油及1份乳化劑{Atmos 3 00 (Atlas Chemical Corp.之註冊商標）}與50份蒸餾水之混合物裝入氣霧容器中，將閥部件安裝至容器，且接著將40份推進劑（LPG )在壓力下經由閥壓縮至容器中，獲得以水爲底質之氣霧劑。調配物實例9 將一張具有蜂巢結構之紙品（0.5公分厚、69公分長及0.2公分寬）從一端捲起，製得5.5公分直徑及0.2公分高之實質的圓柱形載體。將5份酯化合物A及0.5份酯化合物B於94.5份丙酮中的溶液以適當的量均勻地塗覆在上述載體上及接著經空氣乾燥，以移除丙酮，獲得紙製揮發性調配物》 -24- 201236567 調配物實例10 將三維針織布（商標名：Fusion，型號 ’經銷商：Asahi Kasei Fibers Corp.，厚度：基礎重量：321公克/平方公尺；從聚醯胺製得公分直徑之實質的圓形布。將5份酯化合物A 化合物B於94 5份丙酮中的溶液以適當的量在上述三維針織布上及接著經空氣乾燥，以移得編織品揮發性調配物。調配物實例1 1 將97.8重量份乙烯-甲基丙烯酸甲酯共聚烯酸甲酯含量：10重量％，MFR = 2[公克/10 份酯化合物A及0.2份酯化合物B在130°C下旋轉之45毫米《ρ雙螺旋擠壓機熔融揉合，在 40毫米φ擠壓機進一步熔融揉合，將揉合之3 鑄模擠壓成薄片，且接著以冷卻輥冷卻，獲得調配物。調配物實例1 2 將9 7.8重量份乙烯-乙酸乙烯酯共聚物（含量：10重量％，MFR = 2[公克/10分鐘])、2 A及0.2份酯化合物B在130 °C以相同方向旋_The "total effective amount herein" means the total amount of the ester compound A and the ester compound B. The application amount of the two compounds allows the pest to be subjected to the pest control for the administration of the pest control composition of the present invention. Specific examples of the method are the following methods. The administration method can be appropriately selected depending on the form of the pest control composition of the present invention, the administration position, and the like. (1) A method in which the pest control composition of the present invention itself is administered to a habitat in which a pest or a pest inhabits. (2) A method in which the pest control composition of the present invention is diluted with a solvent (-19-201236567 such as water) and then administered to a habitat in which a pest or a pest inhabits. In the method (2), the pest control composition of the present invention formulated into an emulsifiable concentrate, a wettable powder, a flowable concentrate, a microgel or the like is often diluted to make the ester compound A and the ester. The total concentration of the compound B may be from 0.01 to 1,000 ppm. (3) A method in which the pest control composition of the present invention is heated in a habitat in which harmful organisms inhabit, and the active ingredient is evaporated. In the method (3), both the administration dose and the administration concentration of the ester compound A and the ester compound B may depend on the form of the pest control composition of the present invention, when, where and how to apply the pest control system. The composition, the degree of damage, and the like are appropriately determined. When the pest control composition of the present invention is used to prevent an infectious disease, the dose in the case of administration into the space is usually from 0. 0001 to the total amount of the ester compound A and the ester compound B. 1, 〇〇〇 mg / m ^ 3, and the dosage in the case of administration on the application plane is usually 0.0001 to 1 in terms of the total amount of the ester compound oxime and the ester compound 〇〇〇, 〇〇〇 gram / square meter. Volatile formulations which are heated (such as insecticidal insecticides and electrically heated insecticidal tablets) are used by heating to volatilize the active ingredient depending on the type of such formulation. Non-heated volatile formulations (such as resin volatile formulations, paper volatile formulations, non-woven volatile formulations, woven volatile formulations, and sublimed ingots) can be placed, for example, by allowing the formulations to be placed Use air in their space or against the formulation to blow air. -20- 201236567 The space for applying the pest control composition of the present invention to prevent infectious diseases includes closets, closets, wardrobes, sideboards, washrooms, bathrooms, storage rooms, living rooms, restaurants, warehouses, and automobile interiors. . Further, the pest control composition of the present invention can also be used in an outdoor open space. When using the pest control composition of the present invention to prevent ectoparasites of livestock (such as cattle, horses, pigs, sheep, goats, chickens, etc.) and small animals (such as dogs, cats, rats, mice, etc.) The animals can be administered to animals in a manner well known in the art of veterinary medicine. The method of using the pest control composition of the present invention is specifically as follows. The pest control composition for systemic control is administered, for example, in the form of a lozenge, a mixture with a feed, a suppository or an injection (e.g., 'intramuscular, subcutaneous, intravenous or intraperitoneal injection). A pest control composition for non-systemic control is sprayed (pour-on) or instilled (spot-on) with an oily formulation or an aqueous liquid formulation, such as by spraying with an oily formulation or an aqueous liquid formulation. The method of treating, washing the animal with a shampoo formulation, or installing a volatile formulation of the resin in the form of a collar or ear tag to the animal. When the pesticidal composition of the present invention is administered to an animal, the total amount of the ester compound A and the ester compound b is usually in the range of 0.01 to 1, mg in terms of the body weight of the animal per kg. In the pest control composition of the present invention, other pest control preparations (such as insecticides and killers, repellents, synergists, pigments, etc.) may be further mixed with the ester compound A and the ester compound b. </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> <RTIgt; </ RTI> <RTIgt; </ RTI> <RTIgt; </ RTI> <RTIgt; First, examples of the formulation of the pest control composition of the present invention and examples of the test examples are given by mass unless otherwise specified. Formulation Example 1 9 parts of ester compound A and 0.9 part of ester compound B were dissolved in a mixture of xylene and 37.5 parts of N,N-dimethylformamide, 9.1 parts of polyoxyethylene styrylphenyl ether and 6 parts of twelve. An alkylbenzenesulfonate is added thereto, and the resulting mixture is thoroughly stirred and mixed to obtain a concentrate. Formulation Example 2 20 parts of the ester compound A, 20 parts of the ester compound B and 5 parts of 5060 (registered trademark of Toho Chemical Co., Ltd.) were used in an amount of 32 parts of Cardplex #80 (Shionogi & Co., Ltd.) A synthetic hydration cerium oxide fine powder was registered and 23 parts of 300 mesh mesh were added thereto, and the resulting mixture was mixed in a juice machine to obtain a powder. Formulation Example 3 5 parts of synthetic hydrated ceria fine powder, 5 parts of 12-step detail were placed. In addition to £37.5, calcium sulphate emulsifiable S orpo1 is mixed, trademark; algae added wettable alkylbenzene-22- 201236567 sodium sulfonate, 30 parts bentonite and 56_7 parts clay added to 3 parts ester compound A In a mixture with 0.3 parts of the ester compound B' and the resulting mixture was thoroughly stirred and mixed. A suitable amount of water is then added to the resulting mixture and further stirred. The thus stirred mixture was subjected to particle size adjustment by a granulator and then air-dried to obtain granules. Formulation Example 4 5 parts of ester compound A, 0.5 part of ester compound B, 1 part of synthetic hydrated ceria fine powder, 1 part of Driless B (manufactured by Sankyo Co., Ltd.) as a flocculating agent, and 7 parts The clay is thoroughly mixed in the mill and then stirred and mixed in a blender. 85.5 parts of cutting clay (c u t c 1 a y ) was added to the resulting mixture, and the resulting mixture was thoroughly stirred and mixed to obtain a powder. Formulation Example 5 1 part of ester compound A, 1 part of ester compound B, 35 parts of white carbon containing 50% of polyoxyethylene alkyl ether sulfate ammonium salt and 54 parts of water were mixed, and the resulting mixture was wet. The honing method is finely honed to obtain a powder. Formulation Example 6 5 parts of ester compound A and 0.1 part of ester compound B were dissolved in 1 part of dichloromethane, and the resulting solution was combined with 89.8 parts of isoparaffin solvent (Isopar® 'Exxon Chemical Co. Registered trademark) mixed to obtain an oily formulation. -23- 201236567 Formulation Example 7 0.1 part of the ester compound Α, 0. 05 parts of the ester compound B and 49.85 parts of Neochiozol ( Chuokasei Co., Ltd.) were placed in an aerosol can, and the aerosol valve was attached to the aerosol canister. 25 parts of dimethyl ether and 25 parts of LPG were placed in an aerosol can, the aerosol can was shaken and then the actuator was mounted to the aerosol can to obtain an oil-based aerosol. Formulation Example 8 0.5 part of ester compound A, 0.05 part of ester compound B, 0.01 part of BHT, 5 parts of xylene, 3.44 parts of deodorized kerosene and 1 part of emulsifier {Atmos 3 00 (registered trademark of Atlas Chemical Corp.)} A mixture with 50 parts of distilled water is placed in an aerosol container, the valve member is mounted to the container, and then 40 parts of propellant (LPG) is compressed under pressure into the container via a valve to obtain a water-based aerosol. . Formulation Example 9 A paper product having a honeycomb structure (0.5 cm thick, 69 cm long and 0.2 cm wide) was rolled up from one end to obtain a substantially cylindrical carrier of 5.5 cm in diameter and 0.2 cm in height. A solution of 5 parts of the ester compound A and 0.5 part of the ester compound B in 94.5 parts of acetone was uniformly coated on the above carrier in an appropriate amount and then air-dried to remove acetone to obtain a paper volatile formulation. -24- 201236567 Formulation Example 10 A three-dimensional knitted fabric (trade name: Fusion, model ' Dealer: Asahi Kasei Fibers Corp., thickness: basis weight: 321 g/m 2 ; cm diameter from polyamine) Substantially round cloth. A solution of 5 parts of the ester compound A compound B in 94 5 parts of acetone was applied to the above-mentioned three-dimensional knitted fabric in an appropriate amount and then air-dried to obtain a woven volatile formulation. Example 1 1 97.8 parts by weight of methyl ethyl methacrylate copolyenoate content: 10% by weight, MFR = 2 [g gram / 10 parts of ester compound A and 0.2 part of ester compound B were rotated at 130 ° C 45 The millimeter "p double screw extruder melt-kneaded, further melt-kneaded in a 40 mm φ extruder, and the spliced 3 mold was extruded into a sheet, and then cooled with a cooling roll to obtain a formulation. Formulation Example 1 2 will be 9 7.8 parts by weight Ene - vinyl acetate copolymer (content: 10 wt%, MFR = 2 [g / 10 min]), 2 A, and 0.2 parts of the ester compound B at 130 ° C in the same direction of rotation _

φ雙螺旋擠壓機熔融-揉合，再進一步在150°C 米擠壓機進一步熔融揉合，將揉合之產物經I ：AKE69440 4.3毫米， )剪裁成5 及〇 . 5份酯均勻地塗覆除丙酮，獲物（甲基丙分鐘])、2 以相同方向 15(TC下以 I物經由T-樹脂揮發性乙酸乙烯酯份酯化合物 I之45毫米下以40毫 3 T-鑄模擠 -25- 201236567 壓成薄片，且接著以冷卻輥冷卻’獲得樹脂揮發性調配物調配物實例1 3 將5份酯化合物A及0.5份酯化合物B溶解在94.5 份丙酮中，將所得溶液以適當的量塗覆在具有可摺疊結構之紙（2000平方公分）上且經空氣乾燥，以移除丙酮，獲得紙製揮發性調配物。調配物實例1 4 將3份酯化合物A及0.3份酯化合物B溶解在14.6 份丙酮中，獲得溶液。將〇 . 2份氧化鋅、1.0份預膠化澱粉及418份偶氮二甲醯胺添加至溶液中，接著將38.1份水添加至其中。將所得混合物揉合，以擠壓機定型成顆粒且接著乾燥。將含有根據本發明的上述化合物之顆粒容納在中間以鋁隔板分隔之容器的上空間中，且將5 0公克氧化鈣容納在容器的下空間中。因此獲得燻蒸劑。調配物實例1 5 將0.5份氧化鋅、2份預膠化澱粉及97_5份偶氮二甲醯胺混合且將所得混合物以水揉合。將揉合之產物以擠壓機定型成顆粒且乾燥。將2公克顆粒以含有0.58公克醋化合物A及0.058公克酯化合物B之丙酮溶液均勻地浸漬且接著乾燥。將因此獲得的顆粒容納在中間以鋁隔板分隔 -26- 201236567 之容器的上空間中，且將S 0公克氧化鈣容納在容器的下空間中。因此獲得燻蒸劑。調配物實例1 6 將0.5公克酯化合物A及0.05公克酯化合物B溶解在20毫升丙酮中，將所得溶液添加至99.4公克用於防蚊圈之載劑（以4 : 3 : 3之重量比的Tabu粉末、除蟲菊渣與木粉之混合物）與0.3公克綠顔料之混合物中，將所得混合物均句攪拌及混合，將120毫升水添加至其中，將所得混合物充分揉合，且接著將揉合之混合物模製及乾燥，獲得殺蟲圏。調配物實例1 7 將用於具有3.4公分χ2.1公分面積及0.22公分厚度的電片之基底材料（藉由凝結棉絨與紙漿之混合物的原纖維所獲得的平板）以混合1 〇份酯化合物A、1份酯化合物B、39.5份檸檬酸乙醯基三丁酯、39.5份己二酸異壬酯、5份藍顏料與5份調味材料所獲得的溶液均勻地浸漬，獲得用於電加熱之殺蟲片。調配物實例1 8 將〇. 1份酯化合物A及0.01份酯化合物B溶解在 9 9.8 9份脫臭煤油中，將所得溶液放入由氯乙烯所製成的容器中且將吸收芯（藉由凝結無機粉末與黏合劑及烘烤凝 -27- 201236567 結之粉末所獲得）的一端插入容器中，使得芯的其他端可以加熱器加熱，獲得一部分以吸收芯加熱而揮發之調配物調配物實例1 9 將0.2份酯化合物A、0.02份酯化合物B及49.78份 Neochiozol ( Chuokasei Co.，Ltd.)放入氣霧罐中，將氣霧閥安裝至氣霧罐，將25份二甲醚及25份LPG裝入氣霧罐中，搖動氣霧罐且接著將用於全內容物·噴出型氣霧劑之引動器安裝至氣霧罐，獲得氣霧劑。調配物實例2 0 將9 9.78份二乙二醇單乙醚添加至0.2份酯化合物A 及0.02份酯化合物B之混合物中，且將所得混合物充分攪拌及混合，獲得用於防制動物上的外寄生蟲之滴注處理的調配物。調配物實例2 1 將由3份酯化合物A、0.3份酯化合物B及96.7份丙酮所組成的1毫升溶液均勻地塗覆在藉由在壓力下（4噸/ 平方公分）模製4,000毫克2,4,6-三異丙基-1，3,5-三噁烷所獲得的盤形固體物質（直徑：3公分，厚度：3毫米）上，且接著將固體物質乾燥，獲得錠劑。 -28- 201236567 調配物實例2 2 將0.2公克酯化合物a、0.02公克酯化合物B與4公克2,4,6-三異丙基-1，3,5-三噁烷之均勻混合物在壓力下（ 4噸/平方公分）模製成圓盤（直徑：3公分，厚度：3毫米），獲得錠劑。調配物實例2 3 將0.2公克酯化合物a、〇·〇2公克酯化合物B及4公克2,4,6-三異丙基-i，3,5-三噁烷放入50毫升螺旋管中，將該等以加熱熔融，且接著將該等冷卻至室溫，獲得錠劑〇以下的試驗實例論證本發明的有害生物防制組成物對有害生物極佳的防制效果。在以下的試驗實例中，使用（1R)-反式-3-(2，2-二氯乙烯基）-2,2-二甲基環丙烷羧酸[2,3,5,6-四氟-4-(甲氧基甲基）苯基]甲酯作爲酯化合物A。另外，使用3- (2,2-二氯乙烯基）-2,2-二甲基環丙烷羧酸α -氰基-3-苯氧基苯甲酯作爲酯化合物B。試驗實例1 具有如表1中所示之濃度的油性調配物係藉由將特定量之酯化合物Β溶解在異烷烴溶劑（ISOpar Μ，Exxon Chemical Co.之註冊商標）中而製備。該等油性調配物在下文被稱爲比較用組成物（1 )至（3 )。同樣地，具有如 -29- 201236567 表I中所示之濃度的油性調配物係藉由將特定量之酯化合物A溶解在異院烴溶劑（Isopar Μ，Exxon Chemical Co. 之註冊商標）中而製備。該等油性調配物在下文被稱爲比較用組成物（4 )至（6 )。含有如表1中所示之濃度的活性成分之油性調配物係藉由將特定量之酯化合物A及酯化合物B溶解在異烷烴溶劑（Isopar Μ，Exxon Chemical Co.之註冊商標）中而製備，作爲本發明的有害生物防制組成物。該等油性調配物在下文被稱爲本發明組成物（1)至（5)。將10隻蚊子（淡色庫蚊）（10隻雌性）釋放至具有每邊70公分的立方形箱中。將0.7毫升本發明組成物（1 )以噴槍從該箱入口的小窗戶噴灑（噴灑壓力：0.9公斤/ 平方公分）。在噴灑之後7分鐘計算擊落的昆蟲數目及計算擊落（KD)率。進行與上述相同的試驗，除了使用本發明組成物（2 )至（5)及比較用組成物（1)至（6)中之各者代替本發明組成物（1 )以外，且計算在噴灑之後7分鐘的擊落率。將該等試驗重複2次。將結果顯示於表1。 -30- 201236567 表1 酯化合物A之含量 (w/v %) 酯化合物B之含量 (w/v %) 在7分鐘之後的 KD 率(％) 本發明組成物（1) 0.015 0.015 95 本發明組成物（2) 0.015 0.0075 90 本發明組成物（3) 0.00313 0.03 90 本發明組成物（4) 0.00313 0.015 80 本發明組成物（5) 0.00156 0.03 65 比較用組成物（1) - 0.03 30 比較用組成物（2) - 0.015 20 比較用組成物（3) _ 0.0075 10 比較用組成物（4) 0.015 _ 50 比較用組成物（5) 0.00313 20 比較用組成物（6) 0.00156 - 10 工業應用根據本發明，提供對有害生物具有極佳的防制效果之有害生物防制組成物及有害生物之防制方法。 -31 -φ double screw extruder melt-kneaded, further melted and kneaded at 150 ° C rice extruder, the product of the kneading was cut into 5 and 经 by I: AKE 69440 4.3 mm, 5 parts of the ester evenly Coating with acetone, the obtained material (methyl propyl minutes), 2 in the same direction 15 (TC under TC with T-resin volatile vinyl acetate ester ester compound I at 45 mm under 40 mA T-casting -25- 201236567 Pressed into a sheet, and then cooled with a cooling roll' to obtain a resin volatile formulation formulation Example 1 3 5 parts of ester compound A and 0.5 part of ester compound B were dissolved in 94.5 parts of acetone, and the resulting solution was appropriately The amount was applied to a paper having a foldable structure (2000 cm 2 ) and air dried to remove acetone to obtain a paper volatile formulation. Formulation Example 1 4 3 parts of ester compound A and 0.3 part of ester Compound B was dissolved in 14.6 parts of acetone to obtain a solution. 2 parts of zinc oxide, 1.0 part of pregelatinized starch, and 418 parts of azomethicone were added to the solution, followed by adding 38.1 parts of water thereto. The resulting mixture is kneaded and shaped into granules by an extruder Subsequently, the granules containing the above-mentioned compound according to the present invention are accommodated in the upper space of the container partitioned by an aluminum separator in the middle, and 50 g of calcium oxide is contained in the lower space of the container. Thus, a fumigant is obtained. Example 1 5 0.5 parts of zinc oxide, 2 parts of pregelatinized starch and 97_5 parts of azomethicone were mixed and the resulting mixture was kneaded with water. The kneaded product was shaped into granules by an extruder and dried. 2 g of granules were uniformly impregnated with an acetone solution containing 0.58 g of vinegar compound A and 0.058 g of ester compound B and then dried. The granules thus obtained were contained in the upper space of the container separated by an aluminum separator in the middle -26-201236567, And S 0 g of calcium oxide was contained in the lower space of the container. Thus, a fumigant was obtained. Formulation Example 1 6 0.5 g of the ester compound A and 0.05 g of the ester compound B were dissolved in 20 ml of acetone, and the resulting solution was added to 99.4. The mixture used for the anti-mosquito carrier (a mixture of Tabu powder, pyrethrum and wood powder in a weight ratio of 4:3:3) and a mixture of 0.3 g of green pigment The mixture was stirred and mixed, 120 ml of water was added thereto, the resulting mixture was sufficiently kneaded, and then the kneaded mixture was molded and dried to obtain insecticidal mites. Formulation Example 1 7 was used for having 3.4 cm.基底 2.1 cm area and 0.22 cm thickness of the base material of the electric sheet (a plate obtained by condensing the fibrils of the mixture of cotton linters and pulp) to mix 1 酯 ester compound A, 1 part ester compound B, 39.5 parts A solution obtained by acetyl citrate tributyl acrylate, 39.5 parts of isodecyl adipate, 5 parts of a blue pigment, and 5 parts of a flavoring material was uniformly impregnated to obtain an insecticidal sheet for electric heating. Formulation Example 1 8 1 part of ester compound A and 0.01 part of ester compound B were dissolved in 99.8 9 parts of deodorized kerosene, and the resulting solution was placed in a container made of vinyl chloride and the absorbent core was borrowed. One end of the obtained inorganic powder and binder and the powder obtained by baking the coagulation -27-201236567 is inserted into the container, so that the other end of the core can be heated by the heater to obtain a part of the formulation which is heated and volatilized by the absorption core. Example 1 9 0.2 parts of ester compound A, 0.02 parts of ester compound B and 49.78 parts of Neochiozol ( Chuokasei Co., Ltd.) were placed in an aerosol can, and the aerosol valve was installed in an aerosol can, 25 parts of dimethyl ether. And 25 parts of the LPG were placed in an aerosol can, the aerosol can was shaken and then the actuator for the whole contents and the spray-type aerosol was attached to the aerosol can to obtain an aerosol. Formulation Example 20 0 9.78 parts of diethylene glycol monoethyl ether was added to a mixture of 0.2 part of the ester compound A and 0.02 part of the ester compound B, and the resulting mixture was thoroughly stirred and mixed to obtain an outer surface for preventing the brake. Formulation of parasite instillation treatment. Formulation Example 2 1 A 1 ml solution consisting of 3 parts of ester compound A, 0.3 part of ester compound B and 96.7 parts of acetone was uniformly coated by molding 4,000 mg 2 under pressure (4 ton / cm 2 ). A disk-shaped solid matter (diameter: 3 cm, thickness: 3 mm) obtained from 4,6-triisopropyl-1,3,5-trioxane was applied, and then the solid matter was dried to obtain a tablet. -28- 201236567 Formulation Example 2 2 A uniform mixture of 0.2 g of ester compound a, 0.02 g of ester compound B and 4 g of 2,4,6-triisopropyl-1,3,5-trioxane under pressure (4 ton / cm ^ 2 ) molded into a disc (diameter: 3 cm, thickness: 3 mm) to obtain a tablet. Formulation Example 2 3 0.2 g of the ester compound a, 〇·〇 2 g of the ester compound B and 4 g of 2,4,6-triisopropyl-i,3,5-trioxane were placed in a 50 ml spiral tube. The test examples which are melted by heating and then cooled to room temperature to obtain a tablet 〇 below demonstrate the excellent control effect of the pest control composition of the present invention on pests. In the following test examples, (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid [2,3,5,6-tetrafluoro was used. 4-(Methoxymethyl)phenyl]methyl ester was used as the ester compound A. Further, α-cyano-3-phenoxybenzylmethyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate was used as the ester compound B. Test Example 1 An oily formulation having a concentration as shown in Table 1 was prepared by dissolving a specific amount of an ester compound hydrazine in an isoparaffin solvent (ISO Par®, a registered trademark of Exxon Chemical Co.). These oily formulations are hereinafter referred to as comparative compositions (1) to (3). Similarly, an oily formulation having a concentration as shown in Table I of -29-201236567 is prepared by dissolving a specific amount of the ester compound A in a hydrocarbon solvent (Isopar®, a registered trademark of Exxon Chemical Co.). preparation. These oily formulations are hereinafter referred to as comparative compositions (4) to (6). An oily formulation containing the active ingredient at a concentration as shown in Table 1 was prepared by dissolving a specific amount of the ester compound A and the ester compound B in an isoalkane solvent (Isopar®, a registered trademark of Exxon Chemical Co.). As a pest control composition of the present invention. These oily formulations are hereinafter referred to as compositions (1) to (5) of the present invention. Ten mosquitoes (Culex pipiens) (10 females) were released into a cubic box with 70 cm per side. 0.7 ml of the composition (1) of the present invention was sprayed from a small window at the inlet of the box with a spray gun (spraying pressure: 0.9 kg/cm 2 ). The number of shot down insects and the calculated shot down (KD) rate were calculated 7 minutes after spraying. The same test as above was carried out except that each of the compositions (2) to (5) of the present invention and the comparative compositions (1) to (6) were used instead of the composition (1) of the present invention, and the calculation was carried out. After 7 minutes of shooting down. These tests were repeated twice. The results are shown in Table 1. -30- 201236567 Table 1 Content of ester compound A (w/v %) Content of ester compound B (w/v %) KD rate after 7 minutes (%) Composition of the invention (1) 0.015 0.015 95 The present invention Composition (2) 0.015 0.0075 90 Composition of the invention (3) 0.00313 0.03 90 Composition of the invention (4) 0.00313 0.015 80 Composition of the invention (5) 0.00156 0.03 65 Composition for comparison (1) - 0.03 30 For comparison Composition (2) - 0.015 20 Comparative composition (3) _ 0.0075 10 Comparative composition (4) 0.015 _ 50 Comparative composition (5) 0.00313 20 Comparative composition (6) 0.00156 - 10 Industrial application based on The present invention provides a pest control composition and a pest control method which have an excellent control effect against harmful organisms. -31 -

Claims

201236567 VII. Patent application scope: 1 · A pest control composition comprising vinegar compound represented by formula (I): H3COH2C

ω and the ester compound represented by formula (II):

As an active ingredient. 2. The composition according to claim 1, wherein the ester compound represented by the formula (I) has a weight ratio of the ester compound represented by the formula (II) of from 5:1 to 1:50. 3. A pest control method comprising the ester compound represented by formula (I): H3COH.2C

ω and the ester compound represented by the formula (11):

(Π) The total effective amount of the habitat to which the pest or pest inhabits. -32- 201236567 The ester compound represented by the formula (I) F F H3C CH3 HaCOHzC-^-^\ /^-ΟΗ=〇α2 Ο F F and the ester compound represented by the formula (Π):

The use of a combination of (Π) for the control of pests. -33- 201236567 Four designated representatives: (1) The representative representative of the case is: No (2) The symbol of the representative figure is a simple description: No 201236567 5. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention. : Type I