TW201234957A - Device for securing laboratory animal - Google Patents

Device for securing laboratory animal Download PDF

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Publication number
TW201234957A
TW201234957A TW100105131A TW100105131A TW201234957A TW 201234957 A TW201234957 A TW 201234957A TW 100105131 A TW100105131 A TW 100105131A TW 100105131 A TW100105131 A TW 100105131A TW 201234957 A TW201234957 A TW 201234957A
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Taiwan
Prior art keywords
hollow body
chamber
experimental
opening
experimental animal
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TW100105131A
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Chinese (zh)
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TWI392450B (en
Inventor
Sue-Joan Chang
Wen-Jen Yu
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Univ Nat Cheng Kung
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Priority to TW100105131A priority Critical patent/TWI392450B/en
Publication of TW201234957A publication Critical patent/TW201234957A/en
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Publication of TWI392450B publication Critical patent/TWI392450B/en

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Abstract

A device for securing laboratory animal includes: a hollow body having a room which having an entry end, the entry end located on a end of the hollow body and the entry end can be closed by a closing unit, the other end of the hollow body having a adjusting section, and a through hole set on the hollow body and connected with the room; a limiting unit set on the adjusting section of the hollow body and separating a predetermined limiting space from the room.

Description

201234957 六、發明說明: 【發明所屬之技術領域】 本發明係關於一種實驗動物保定裝置,特別是—種具 有可調式限位空間之實驗動物保定裝置。 【先前技術】 現今醫藥領域多致力於動物實驗之研究,以期望藉由 活體實驗動物對藥物或外來刺激(例如:電擊、病菌···等) 引發之生理及藥理作用,進一步預測人體於相同藥物或刺 激下所產生之反應以作為臨床治療之基礎。 傳統用以評估實驗動物生理或藥理狀態之方法,係大 致分為清醒模式(conscious m〇del)以及麻醉模式(咖她咖 model)。清醒模式常見的操作手段係於實驗動物維持活動 力之情況下’以灌食、皮下注射、腹腔注射、尾部靜脈注 =等::對該實驗動物進行給藥、採血…等,而麻醉模 式則必須先⑽_騎於實驗動物後,再於手術台 該實驗動物進㈣樣、藥物監控···等。然而,不論採用上 述那種域實驗,當必 :醉或體外刺激(例如:冷熱 =將 =人:,間一實驗進行= 驗動=:=^=作需求’目前已開發出多種實 性及安錄。料日^提升祕實祕操物程之便利 M25871G號「實軸物保定^專職 201234957 驗動物保疋裝置9,該實驗動物保定裝置$係包含一長型 盒體^1及-壓板92,該壓板92係容置於該長型盒體91 之谷至911内,且該長型盒體91之二相對的長軸側板係 分別形成有二組相對之數插孔912、913,該二組插孔912、 913係連通於該容室9n ’且分別以一插栓%貫穿該二組 插孔912、913 ’帛以限制該壓板92於該容室911内之位 置。又’該長型盒體91之二相對的短軸側板係形成二相對 之開口 914 ’且该開口 914係連通於該容室911,用以供實 驗動物94之尾部外露。 如此操作者係能夠將實驗動物94置於該長型盒體 91之今至911内’且藉由該二插栓93與二組插孔 之配合’使得板92能夠闕該實驗動物體94,且同 =吏該實驗動物94之尾部經由該短軸側板之開口 914外 露’以限制該實驗動物94於該長型盒體91之容室911内, 而方便進行尾部靜脈採血或尾壓量测之操作。 然而,上述習知實驗動物保定裝置9利用該壓板92 限制該實驗動物94之活動空間時,該壓板92係對該實驗 動物94施于下壓之力4,而於該實驗動物%身上產生壓 L之行為口此’往在谷易引發該實驗動物94額外的生理 反應(例如:f上腺素激升、血壓增高...#),進而對量測 或採血後的評估數據造成不良的影響。 再者,於操作該習知實驗動物保定裝置9時,不僅需 以該壓板92 _該實驗祕94,甚至續同時另以該插 栓93對應該插孔912、913調整該壓板92之位置,才能夠 因應體型不同之實驗動物達到限制其活動之翻。如此, 201234957 不僅增加使用者於操作過程之不便利性,甚至相對 個實驗流程所需耗費之時間。 第所:,如中華民國公告 J揭式動物手術台」專利案,係揭示另一 種實驗動物保定裝置8,該實驗動物保定裝置8係一 手術平台81及—魔鬼㈣,該魔減82係設置於該:術 ΙΐΛΓΓ,用以配合該魔鬼枯82相互對應的絨毛部 二二此’域麵能夠將實驗動物Μ置於該手術 =上’且__鬼# 82相互_的絨毛部 部固定該貫驗動物83之手、 Ίή 臥於該手術平么81卜手腳以限制該實驗動物83狀 口 81上,而能夠於不需壓迫 之情況下進行採血或採樣之操作。 ㈣動物83 實驗動物較裝置8雖改善上述實驗動 =:板92對實驗動物94所造成之壓迫行為。缺而, 驗動物83之活動。因,台81上,才能夠限制該實 動因此,於操作過程需先以操作者之雔丰 能〜方=:=si :將該:驗動物834之手、腳攤開’才 進仃固定。於此過程中,不僅因實驗動 實驗動困難度,更無法因此解決該上述 驗偏、、之使用不便利性,甚至更可能於玆實 驗操作人3員之。 間,甚與軸簡姉之時 另外,如中華民國公告第126793號「犬猶安全注射 201234957 固疋龍」專利荦 一 驗動物保定裝置係籠=物保定裝置,該實 以調整該固定气之=疋龍内上下、左右移動之特性,用 動物,進而以:定、夠因f大小不同之實驗 固定蘢之㈣* η κ 4方式將該實驗動物限制於該 操作者之安i 以方便對該實驗動物進行注射且保護201234957 VI. Description of the Invention: [Technical Field of the Invention] The present invention relates to an experimental animal Baoding device, and more particularly to an experimental animal Baoding device having an adjustable limit space. [Prior Art] Nowadays, the medical field is devoted to the research of animal experiments, and it is expected that the physiological and pharmacological effects caused by drugs or external stimuli (eg, electric shock, germs, etc.) will be further predicted by the living laboratory animals. The response produced by drugs or stimuli serves as the basis for clinical treatment. Traditional methods for assessing the physiological or pharmacological state of experimental animals are largely divided into conscious mode (conscious 〇del) and anesthesia mode (caffey model). The common operation method of awake mode is to use the feeding animal, subcutaneous injection, intraperitoneal injection, tail vein injection, etc. in the case of maintaining the activity of the experimental animal:: administering the animal to the experimental animal, collecting blood, etc., while the anesthesia mode is You must first (10)_ ride on the experimental animal, and then enter the (four) sample, drug monitoring, etc. on the operating table. However, regardless of the domain experiment described above, it must be: drunk or in vitro stimulation (eg: hot and cold = will = human: inter-test = test ===== for demand') has developed a variety of real and An Lu. The date of the day ^ enhances the secret of the secret secrets of the physical process M25871G "real axis Baoding ^ full-time 201234957 animal inspection device 9, the experimental animal Baoding device $ contains a long box ^1 and - pressure plate 92 The pressing plate 92 is received in the valley of the elongated box 91 to 911, and the two opposite long-axis side plates of the elongated box 91 are respectively formed with two sets of opposite jacks 912, 913. The two sets of jacks 912 and 913 are connected to the chamber 9n ′ and respectively extend through the two sets of jacks 912 , 913 ′ by a plug % to limit the position of the pressure plate 92 in the chamber 911. The opposite short-axis side plates of the elongated box body 91 form two opposite openings 914' and the opening 914 is in communication with the chamber 911 for exposing the tail of the laboratory animal 94. Thus, the operator is capable of placing experimental animals. 94 is placed in the long box 91 to 911' and cooperates with the two sets of jacks by the two plugs 93 The plate 92 is enabled to smash the experimental animal body 94, and the tail of the experimental animal 94 is exposed through the opening 914 of the short-axis side plate to limit the experimental animal 94 to the chamber 911 of the elongated casing 91, The operation of the tail vein blood collection or the tail pressure measurement is convenient. However, when the above-mentioned conventional experimental animal Baoding device 9 uses the pressure plate 92 to limit the activity space of the experimental animal 94, the pressure plate 92 is applied to the experimental animal 94. The force of pressure 4, and the behavior of the experimental animal% of the pressure L this mouth to the valley to trigger the experimental animal 94 additional physiological reactions (for example: f adrenaline rush, blood pressure increased ... #) And further adversely affecting the measurement data after measurement or blood collection. Furthermore, when operating the conventional experimental animal Baoding device 9, it is not only necessary to use the pressure plate 92 _ the experimental secret 94, or even continue with the insertion The plug 93 adjusts the position of the pressure plate 92 corresponding to the jacks 912 and 913, so that the experimental animals of different sizes can reach the limit of the activity. Therefore, 201234957 not only increases the inconvenience of the user during the operation, but even the relative The time required for the experimental process. The first:, such as the Republic of China Announcement J Jieshi Animal Operating Table patent case, reveals another experimental animal Baoding device 8, the experimental animal Baoding device 8 is a surgical platform 81 and - the devil (4) The devil reduction 82 series is set in the: ΙΐΛΓΓ ΙΐΛΓΓ, to match the devil's dead 82 corresponding to the villus part 22, this 'domain surface can put the experimental animal Μ on the surgery = up' and __ ghost # 82 The villus portion of the mutual _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ operating. (4) Animals 83 The experimental animals improved the above experimental activity compared with the device 8 =: The compression behavior caused by the plate 92 on the experimental animals 94. Missing, the activity of animal 83. Because, on the station 81, it is possible to limit the actual movement. Therefore, in the operation process, it is necessary to first use the operator's 雔 能 〜 方 = = = = = : : : = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = . In this process, not only is it difficult to experiment with the experiment, but it is also impossible to solve the above-mentioned test bias, and the use is inconvenient, and it is even more likely that the operator will be tested. In addition, when the axis is simple, in addition, such as the Republic of China Announcement No. 126793 "Canine Jue Safety Injection 201234957 Gu Yulong" patent 荦 an animal inspection device cage = material Baoding device, this is to adjust the fixed gas = The characteristics of moving up and down and left and right in the dragon, using the animal, and then limiting the experimental animal to the operator's safety by means of the experiment of fixing the size of the f (4) * η κ 4 The experimental animal is injected and protected

動物知專利案僅能夠應用於犬、猶等大型 易使該Ϊ驗動小型實驗動物時’係容 者籠中㈣不安,甚至捲縮於操作 度、,、、因此二加實驗進行所需耗費之時間及困難 因二=利案之實驗動物保定裝置係無法徹底 〜谷種不同大小之動物做適當的調整。 攔:i;該=專利案所使用之固定籠係依賴多層的栅 ’該固定11的製造過賴經由較繁複的 提二::::r較多的製造成本及時間, 有鑑於上述種種原因,該習知實驗動物保定 仍有加以改善之必要。 啼耳 【發明内容】 本發明之主要目的乃改良上述缺點,提供一種實驗動 物保定裝置,其係能夠避免對實驗動物進行壓迫,以維持 實驗動物的正常生理狀態而保有實驗數據之準確度。、’、 本發明之次一目的係提供一種實驗動物保定^置,係 201234957 i::操作之便利性’以降低操作過程所需耗費之時間 本發月之再目的係提供—種實驗動物保 實驗動物於操作過輕發生掙脫或衝撞之s,: 確保實驗操作人員的安全性。野杈之仃為,以 本發明之又一目的係提供—種 / 能夠減少製造過程的,、疋裝置,係 的時間及成本。貞步驟’以降低製作過程所需耗費 本發明之另一目的係接供_與 能夠依實驗動物之體積而改㈣只驗動物保定裝置,係 之體觀改變該限位空間 不同體型之實驗動物放置者。 以因應 ,達=述發明目的,本發明之實驗動物 係包含二中空體,係具有—腔室,該腔室具—入ί端, 該入口‘係位於該中空ώ 湘杜㈣w 且該人明係可以被一 :孔二二Γ空體另—端具—調整部’該中空體另設 一牙孔與該腔至相互連通;及一限位件,係結合於該中空 體之调整部’用以將該腔室區隔出—預定大小之限位空間。 ^日狀實驗動物保定裝置,其中賴·係可以為 數插槽,該數插槽係位於該中空體之外周壁,且該數插槽 係沿該巾空體之軸向方向_人口端_缝。數插 一々本發明之實驗動物保定裝置,其中該調整部係可以為 :第一開口’该第二開口與該腔室相連通,該限仇件係結 合在該第二開口。又’該第二開口之内周壁與限位件可以 為可互相螺合之螺紋結構。 本發明之實驗動物保定裝置,其中該穿孔係可以位於 201234957 該封閉件。 本發明之實驗動物保定裝置,其中該中空體之外周壁 係可以設有數刻度。 【實施方式1 為讓本發明之上述及其他目的、特徵及優點能更明顯 易懂,下文特舉本發明之較佳實施例,並配合所附圖式, 作詳細說明如下:Animals know that the patent case can only be applied to dogs, jujubes, etc., when the small experimental animals are allowed to test the small experimental animals, the "consistency cages (4) are uneasy, and even curled up in the operation degree, and therefore, the cost of the two-addition experiment is required. The time and difficulty of the experimental animal Baoding device system can not be completely adjusted to the appropriate size of the animal of different sizes. Block: i; the fixed cage used in the patent case relies on a multi-layered grid. The manufacture of the fixed 11 relies on the more complicated manufacturing costs and time of the second::::r, for the above reasons. The conventional experimental animal Baoding still needs to be improved. SUMMARY OF THE INVENTION The main object of the present invention is to improve the above disadvantages, and to provide an experimental animal retention device capable of avoiding compression of an experimental animal to maintain the normal physiological state of the experimental animal while maintaining the accuracy of the experimental data. ', the second objective of the present invention is to provide an experimental animal Baoding, set 201234957 i:: the convenience of operation 'to reduce the time required for the operation process, the purpose of this month is to provide - experimental animal protection The experimental animals are free to break free or collide when operating: To ensure the safety of the experimental operators. It is a further object of the present invention to provide a time/cost that can reduce the manufacturing process, the device, and the system.贞Step 'to reduce the cost of the production process. Another object of the present invention is to provide a _ _ and can change according to the volume of the experimental animal. (4) Only the animal baoding device, the body of the experiment changes the experimental animal of different body types in the space. Placer. In accordance with the purpose of the invention, the experimental animal of the present invention comprises a hollow body having a chamber, the chamber having an inlet end, the inlet being located in the hollow 湘 湘 du (4) w and the person The system can be connected to the cavity of the hollow body by a hole and a second end of the hollow body, and the end of the hollow body is connected with the cavity to communicate with each other; and a limiting member is coupled to the adjusting portion of the hollow body. The chamber is partitioned from a predetermined size limit space. ^ Day-like experimental animal Baoding device, wherein the Lai system can be a plurality of slots, the number of slots is located in the outer peripheral wall of the hollow body, and the number of slots is along the axial direction of the towel body_population end_seam . The experimental animal holding device of the present invention may be inserted, wherein the adjusting portion may be: a first opening, the second opening is in communication with the chamber, and the binding member is coupled to the second opening. Further, the inner peripheral wall of the second opening and the limiting member may be screwed structures that can be screwed to each other. The experimental animal Baoding device of the present invention, wherein the perforation system can be located at 201234957. The experimental animal Baoding device of the present invention, wherein the outer peripheral wall of the hollow body can be provided with a plurality of scales. The above and other objects, features, and advantages of the present invention will become more apparent from the aspects of the invention.

〜請參照第3圖所示,本發明第一實施例之實驗動物保 疋裝置係L 3中空體1及一限位件2,該限位件2係結 合於,中空體1之—側’用以將該巾空體1之内部區隔出 一預定大小之限位空間S。 _ j以選擇為各種幾何形狀之物件(例 =· & ?、盒狀..·等),且該中空體】係具有一腔室n及 入端12,該腔室u為一該實驗動物放置之限位空間 ΜίΓ入口^ 12係位於該腔室U之—端,用以供實驗動物 _ J咏、大鼠、兔...等)放置於該中空體1之腔室11 二;空體1較佳係選擇為管狀體,藉此係能夠 驗動物較舒適之放置環境。於本實施例中,該中 閉,在\, 人口端12係可以被-封閉件122封 …入,•其中外蓋將該腔 之周壁係形成有相對應之螺紋,封閉件122 螺合於該人口端12之開口 靖閉件122能夠 ^12之開π 121處。該中空體丨另具有一穿 201234957 孔13,該穿孔13係與該腔室u相互連通,其中,該穿孔 13係可以選料於該中空體2之任意位置,用以供實驗人 員經由該穿孔13對實驗動物進行採血、注射...等實驗操 作。於本實施例中,該穿孔13較佳係貫穿該封閉件⑵ ^連通於該腔室11,藉以方便實驗人員對實驗動物進行後 續實驗操作。 /再者’該中空體1另設有一調整部Η,該調整部14 係位=該腔室11之另—端,用以供該限位件2於該調整部 Η任意移動’進岐魏限位㈣8之大小。於本實施例 申’該調整部14係形成有數插槽14卜該數插槽⑷係位 於該中空體1之外周壁且沿該中空體丨之軸向方向朝該入 口端12間隔設置’各該插槽141間之間隔係因應操作者之 需求而選擇適當之㈣,其中,該數插槽141係可以選擇 為弧形缺口,且較佳係能夠貫穿該中空體1的外周壁形成 二相對應之缺口,使得該插槽141係具有較佳的定位效 果。另,為提供該腔室11内之實驗動物足夠的氧氣,本實 施例係可以選擇於該調整部14設有一開孔142,使得該開 孔142連通於該中空體i之腔室u,藉此維持該腔室 内之空氣暢通。又,本實施例還可以選擇於該中空體i之 外周壁設有數刻度15,藉由該刻度15係能夠精^量測實 .驗動物之體型’而方便該限位件2選擇適當之插槽141以 改變該限位空間S之大小。 該限位件2係結合於該中空體1之調整部14,用以將 ,該腔室11區隔出預定大小之限位空間S,該限位空間3係 由該限位件2結合於該調整部μ之位置與該入口端n所 —10 ·— 201234957 圈圍而成(如第4圖所示),其中’該預定大小之限位空間s 係指因應不同體型之實驗動物而區隔出符纟該實驗動物體 型的適當限制範圍。於本實施例中,該限位件2係貫穿該 二相對應之缺π且定位於雜槽141巾,藉由該限位件2 插設於不同插槽141之位置係能夠改變該限位空間s之大 小,使得該限位空間s經由該限位件2之調整而能夠因應 各種體型之實驗動物放置。其中,該限位件2係可以因應 該調整部14之插槽141的尺寸,而選擇各種尺寸不同且不 限疋形狀之片體(例如:長型片體、圓弧型片體…等)。如 此,係能夠移動該限位件2插設於不同位置之插槽141, 而改變該限位空間S之大小以放置不同體型的實驗動物, 使得該中空體丨之腔室U具有較佳實驗動物保定之功效。 請參照第4及5圖所示,其係本發明第一實施例之實 驗動物保定裝置使用於體型較大之實驗動物R之情形,此 時,該限位件2係插設於遠離該入口端12的插槽141内, 使得該限位空間S維持較大的容納範圍(如第4圖所示), 接著,將該實驗動物R由該入口端12之開口 121放置於 該限位空間S内,使得該實驗動物R之尾部係能夠由該穿 孔13外露於該中空體1之外,再以該封閉件122螺合於該 開口 121處而封閉該腔室U。如此,僅需將該實驗動物R 限制於該限位空間S内,便能夠於該實驗動物R不需麻醉 之情況下,輕易經由該穿孔13對該實驗動物R進行後續 抽血、注射…等的實驗操作。 請參照第6圖所示,其係本發明第—實施例之實驗動 物保定裝置使用於體型較小之實驗動物R之情形,此時, —U 7 201234957 二广件2係插設於靠近該人口端12的插槽⑷内, -、位空間s維持較小的容納範圍,接著,再依昭上 同之方法將該實驗動㈣限制於該限位空間s内:、=才目 係能夠㈣經由該穿孔13 _實驗動物R 括 血、注射···等的實驗操作。 抽 本發明之實驗動物保技置係能夠利用 ^的調整部Η設計與限位件2配合,使得該限位件2 :入於該中空體i之腔室U以區隔出該限位空間S,且方 該限位件2於該中空體1之腔室u位置,藉此,係 =夠輕易以紐位件2改變該限位空間s之大小,且於 =力^及不需麻醉該實驗動物R之情況τ輕易將不同 驗動祕做贿位㈣s,以維持實驗動物的 正吊生理狀態而保有較佳的實驗數據準確度。再者,甚至 =^的結構設計方便實驗人㈣行操作,崎短實驗所 =!之時間,更可以防止於操作過程發生實驗動物掙脫 或衝撞之打為,而提升實驗操作人員之安全性。 物禪=照第7 81所示’其係本發明第二實施例之實驗動 物保疋I㈣包含-中空體3及—限位件4,該中空體3 與第一實施例相同,係具有一腔室31及_入口端%,咳 入口端32係位於該腔室31之一端,且該入口端^可以為 一第一開口 321 ’該入口端32可以選擇以一封閉件322予 以封閉,且該中空體3可以設一穿孔33,該穿孔33可以 在該封閉件322 ’以及,該中空體3之外周壁也可以設有 數刻度35。在本實施例當中,該中空體3另設一調整部料, 該限位件4係結合於該調整部34,用以將該中空體3之腔 —12—— 201234957 至31區隔出一預定大小之限位空間s。其中,該中空體3 之5周整部34係形成-第二開口 341,該第二開口 341與該 中空體3之腔室31相連通,且該第二開口 341之内周壁較 佳係形成敎結構,以及,該限位件4亦設有能相螺合於 Ί 341之螺紋結構,以使該限位件4能夠經由該 第二開口 341進出該中空體3之腔室3卜藉此,係能夠藉 由該限位件4_中空體3之微調,以達到較佳微調該限- Refer to FIG. 3, the experimental animal protection device according to the first embodiment of the present invention is a L 3 hollow body 1 and a limiting member 2, and the limiting member 2 is coupled to the side of the hollow body 1 The inner space of the towel body 1 is separated by a predetermined size space S. _ j to select objects of various geometric shapes (example = · & ?, box shape ....., etc.), and the hollow body has a chamber n and an inlet end 12, the chamber u is an experiment The space for the placement of the animal ΜίΓ inlet ^ 12 is located at the end of the chamber U for the experimental animal _ J咏, rats, rabbits, etc.) placed in the chamber 11 of the hollow body 1; The hollow body 1 is preferably selected as a tubular body, whereby the environment in which the animal is more comfortable can be examined. In this embodiment, the middle closed, at the population end 12 can be sealed by the closure member 122, wherein the outer cover forms a corresponding thread on the peripheral wall of the cavity, and the closure member 122 is screwed to The opening closure 122 of the population end 12 can be opened at π 121. The hollow body has a hole 13 through the 201234957, and the hole 13 is in communication with the chamber u, wherein the hole 13 can be selected at any position of the hollow body 2 for the experimenter to pass through the hole. 13 Experimental experiments were carried out on blood samples, injections, etc. of experimental animals. In the present embodiment, the perforation 13 is preferably connected to the chamber 11 through the closure member (2) to facilitate the experimental operation of the experimental animal by the experimenter. / Further, the hollow body 1 is further provided with an adjusting portion 系, the adjusting portion 14 is at the other end of the chamber 11 for allowing the limiting member 2 to move freely in the adjusting portion Limit (four) 8 size. In the present embodiment, the adjusting portion 14 is formed with a plurality of slots 14 (4) located on the outer peripheral wall of the hollow body 1 and spaced apart from the inlet end 12 in the axial direction of the hollow body ' The spacing between the slots 141 is appropriately selected according to the needs of the operator (4), wherein the number of slots 141 can be selected as an arc-shaped notch, and preferably can form a two-phase through the outer peripheral wall of the hollow body 1. Corresponding notches make the slot 141 have a better positioning effect. In addition, in order to provide sufficient oxygen for the experimental animal in the chamber 11, the embodiment may be configured such that the adjusting portion 14 is provided with an opening 142, so that the opening 142 is connected to the chamber u of the hollow body i, This keeps the air in the chamber clear. In addition, in this embodiment, a plurality of scales 15 may be selected on the outer peripheral wall of the hollow body i, and the scale 15 can be used to accurately measure the body shape of the animal, and the limiter 2 is selected to be properly inserted. The groove 141 changes the size of the limit space S. The limiting member 2 is coupled to the adjusting portion 14 of the hollow body 1 for partitioning the chamber 11 into a limiting space S of a predetermined size, and the limiting space 3 is coupled to the limiting member 2 by the limiting member 2 The position of the adjusting portion μ is circled by the inlet end n—10 ·—201234957 (as shown in FIG. 4 ), wherein “the predetermined size limit space s refers to the area of the experimental animal according to different body types. The appropriate limits for the size of the experimental animal are excluded. In this embodiment, the limiting member 2 is inserted through the corresponding π and is located in the slot 141. The position of the limiting member 2 inserted in the different slot 141 can change the limit. The size of the space s enables the limit space s to be placed in response to the adjustment of the limit member 2 in response to various types of laboratory animals. In the limiter 2, the size of the slot 141 of the adjustment unit 14 can be selected, and the pieces having different sizes and not limited to the shape can be selected (for example, a long piece, a circular piece, etc.) . In this way, the limiting member 2 can be moved into the slot 141 at different positions, and the size of the limiting space S can be changed to place experimental animals of different sizes, so that the chamber U of the hollow body has better experiment. The efficacy of animal Baoding. Referring to Figures 4 and 5, the experimental animal Baoding device according to the first embodiment of the present invention is used in the case of a larger experimental animal R. At this time, the limiting member 2 is inserted away from the entrance. In the slot 141 of the end 12, the limiting space S is maintained in a large receiving range (as shown in FIG. 4), and then the experimental animal R is placed in the limiting space from the opening 121 of the inlet end 12. In S, the tail portion of the experimental animal R can be exposed from the hollow body 1 and the closure member 122 is screwed to the opening 121 to close the chamber U. In this way, the experimental animal R is restricted to the restriction space S, and the experimental animal R can be easily subjected to subsequent blood drawing, injection, etc. via the perforation 13 without anesthesia. Experimental operation. Please refer to FIG. 6 , which is the case where the experimental animal Baoding device of the first embodiment of the present invention is used in the case of the experimental animal R having a smaller size. At this time, the U 2 201234957 two wide pieces 2 are inserted in the vicinity. In the slot (4) of the population end 12, - the bit space s maintains a small accommodation range, and then, according to the same method, the experimental motion (4) is limited to the limit space s: (4) Experimental operation through the perforation 13 _ experimental animal R blood, injection, etc. The experimental animal maintenance device of the present invention can be configured to cooperate with the limiting member 2 by using the adjusting portion ^, so that the limiting member 2 is inserted into the chamber U of the hollow body i to partition the limiting space. S, and the limiting member 2 is located at the chamber u of the hollow body 1, whereby the system is sufficient to change the size of the limiting space s with the button member 2, and the force is not required to be anesthetized The condition of the experimental animal R τ easily makes a different bribe (4) s to maintain the physiological state of the experimental animal while maintaining better experimental data accuracy. In addition, even the structure design of =^ is convenient for the experimenter (4) to operate, and the time of the short test site =! can prevent the experimental animals from breaking free or colliding during the operation, and improve the safety of the experimental operators.物禅=, according to the seventh embodiment, the experimental animal protection I (4) according to the second embodiment of the present invention comprises - a hollow body 3 and a stopper 4, which is the same as the first embodiment, has a The chamber 31 and the inlet end % are located at one end of the chamber 31, and the inlet end ^ can be a first opening 321 '. The inlet end 32 can be selectively closed by a closure member 322, and The hollow body 3 can be provided with a perforation 33 which can be provided with a plurality of graduations 35 on the outer peripheral wall of the closure member 322' and the hollow body 3. In the embodiment, the hollow body 3 is further provided with an adjusting portion, and the limiting member 4 is coupled to the adjusting portion 34 for separating the cavity 12 - 201234957 to 31 of the hollow body 3 The limit space s of the predetermined size. The entire circumference 34 of the hollow body 3 is formed by a second opening 341, and the second opening 341 is in communication with the chamber 31 of the hollow body 3, and the inner peripheral wall of the second opening 341 is preferably formed. The cymbal structure, and the limiting member 4 is also provided with a threaded structure that can be screwed to the Ί 341 so that the limiting member 4 can enter and exit the chamber 3 of the hollow body 3 via the second opening 341. , by the fine adjustment of the limiting member 4_ hollow body 3, to achieve better fine-tuning

工間S之放果,以進一步提升各種體型實驗動物R容納 於該限位空間S之裕度。 請參照第8及9圖所示,其係本發明第二實施例之 ^動物保定裝置使用於體型不同之實驗動物之情形,此 時,6亥限位件4係利用螺紋結構結合於該調整部34之第二 H34i處,以先封閉該調整部34之第二開口 341且使得 明第維持—較大的容納範圍,接著,再依照本發 例之方法將實驗動物R由第—開口 32ι容置於 該限位空間S内,铺得兮♦ , ' 外露於該中空體3 陳由該穿孔% 處之螺紋結觀合„=^件4與第二開口 341 於哕腔m〜 Λ輕㈣整該限位件4伸入 間得辦驗祕R關於該限位空 保定裝置係具有較佳的操作便利驗動物 驗動物R之體型。 m 更此夠付合不同實 進行ίΓ 月之實驗動物保定裝置係能夠避免對實驗動物 進仃壓迫,以維持實驗動物的貫驗動物 有實驗數據準確度之功 纟紅,進而達到保The result of the work room S is to further enhance the margin of the various types of experimental animals R accommodated in the limit space S. Please refer to the eighth and ninth embodiments, which are used in the case of the experimental animals of different sizes according to the second embodiment of the present invention. At this time, the 6-heel limit member 4 is coupled to the adjustment by using a thread structure. At the second H34i of the portion 34, the second opening 341 of the adjusting portion 34 is first closed and the first maintaining range - the larger receiving range, and then the experimental animal R is opened by the first opening 32 in accordance with the method of the present example.容 该 该 , , , , , , , , , , , , , , , , , , , , , , , , 外 外 兮 兮 兮 兮 兮 兮 兮 兮 兮 兮 该 该 该 该 该 该 该 该 该 该 该 该 该 该(4) The whole limiter 4 is inserted into the room to be examined. R. The limit air-locking device has a better operation and facilitates the animal test of the animal R. m. This is more than enough to carry out the experiment. The animal Baoding device can avoid the pressure on the experimental animals to maintain the experimental data of the experimental animals with the accuracy of the experimental data, and thus achieve the protection

—13 S 201234957 祕,2明,貫驗動物保定裝置係能夠增加操作之便利 ’’降低操作過程所需耗費之時間及困難度。 操作過驗動物保定裂置係能夠避免實驗動物於 产Η生=脫或衝撞之行為,以降低實崎作人員的 危險性,達到提升操作安全性之功效。 限位^ΐ 驗動物保定裝置係能魅有較佳微調該 ^限二二進—步提升各種體型實驗動物容納於 之聲之#軸純定裝置雜_少於製造過程 之繁續步驟’㈣到降低實驗操作人員成本㈣之功效。 以本發明已·上述較佳實施例揭示,然其並非用 =本發明,任何熟習此技藝者在不麟本發明之精神 恭a!之内’相對上述實施例進行各種更賴修改仍屬本 毛月所保護之技術蔚藏,田+士又义口口 之申請專利翻^定者^本保護範圍當視後附 【圖式簡單說明】 第1圖··習知實驗動物保定裝置之立體示意圖。 第2圖··習知實驗動物保定裝置之剖面示意圖。 第3圖.本發明第一實施例之立體分解圖。 第4圖.本發明第一實施例之組合剖視圖。 第5圖:本發明第一實施例之作動剖視圖一。 第6圖··本發明第一實施例之作動剖視圖二。 第7圖··本發明第二實施例之立體分解圖。 —14 — 201234957 第8圖:本發明第二實施例之組合剖視圖。 第9圖:本發明第二實施例之作動剖視圖。 【主要元件符號說明】 〔本發明〕—13 S 201234957 Secret, 2 Ming, the inspection animal Baoding device can increase the convenience of operation ’’ reduce the time and difficulty of the operation process. The operation of the animal inspection Baoding cleavage system can avoid the behavior of the experimental animals in the production of cockroaches = off or collision, in order to reduce the risk of the real people, and achieve the effect of improving the safety of operation. Limits ΐ 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 动物 ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ ^ To reduce the cost of the experimental operator (four). The present invention has been disclosed in the above preferred embodiments, but it is not intended to be used in the present invention, and any skilled person in the art is not in the spirit of the present invention. The technology protected by Maoyue is arbitrarily, and the application for patent protection by Tian+shi and Yikoukou is the subject of protection. The scope of protection is attached as follows: [Simplified description of the diagram] Figure 1··Three-dimensional of the experimental animal Baoding device schematic diagram. Fig. 2 is a schematic cross-sectional view of a conventional experimental animal Baoding device. Fig. 3 is a perspective exploded view of the first embodiment of the present invention. Fig. 4 is a sectional view showing the combination of the first embodiment of the present invention. Fig. 5 is a cross-sectional view showing the first embodiment of the present invention. Fig. 6 is a cross-sectional view of the first embodiment of the present invention. Fig. 7 is a perspective exploded view of a second embodiment of the present invention. —14 — 201234957 Figure 8 is a cross-sectional view of a combination of a second embodiment of the present invention. Figure 9 is a cross-sectional view showing the second embodiment of the present invention. [Description of main component symbols] [Invention]

1 中空體 11 腔室 12 入口端 121 開口 122 封閉件 13 穿孔 14 調整部 141 插槽 142 開孔 15 刻度 2 限位件 3 中空體 31 腔室 32 入口端 321 第一開口 322 封閉件 33 穿孔 34 調整部 341 第二開口 35 刻度 4 限位件 S 限位空間 R 實驗動物 〔習知〕 9 實驗動物保定裝置 91 長型盒體 911 容室 912 插孔 913 插孔 914 開口 —15 — 201234957 92 壓板 93 94 實驗動物 8 實驗動物保定裝置 81 82 魔鬼粘 83 插栓 手術平台 實驗動物 —16 —1 hollow body 11 chamber 12 inlet end 121 opening 122 closure 13 perforation 14 adjustment portion 141 slot 142 opening 15 scale 2 stop 3 hollow body 31 chamber 32 inlet end 321 first opening 322 closure 33 perforation 34 Adjustment part 341 second opening 35 scale 4 limit piece S limit space R experimental animal [conventional] 9 experimental animal Baoding device 91 long box 911 chamber 912 jack 913 jack 914 opening - 15 — 201234957 92 pressure plate 93 94 Laboratory Animals 8 Experimental Animal Baoding Device 81 82 Devil Stick 83 Plug Operation Platform Experimental Animals - 16 —

Claims (1)

201234957 • 七、申請專利範圍: 1、 一種實驗動物保定裝置,係包含: —中空體,係具有一腔室,該腔室具一入口端,該入口 端係位於該中空體之一端,且該入口端係可以被一封閉 件封閉,該中空體另一端具一調整部,該中空體另設一 穿孔與該腔室相互連通;及 一限位件,係結合於該中空體之調整部,用以將該腔室 鲁 區隔出一預定大小之限位空間。 2、 依申請專利範圍第1項所述之實驗動物保定裴置,其中 該調整部係可以為數插槽’該數插槽係位於該中空體之 外周壁,且該數插槽係沿該中空體之軸向方向朝該入口 端間隔設置。 3、 依申請專利範圍第2項所述之實驗動物保定裝置,其中 該調整部之數插槽係為貫穿該中空體之外周壁的二相 對應缺口。 _ 4、依申請專利範圍第1或2項所述之實驗動物保定裝置, - 其中該s周整部另設有一開孔’5亥開孔係連通該中空體之 腔室。 5、 依申請專利範圍第丨項所述之實驗動物保定裝置,其中 該調整部係形成一第二開口,該第二開口與該腔室相連 通,該限位件係結合在該第二開口。 6、 依申請專利範圍第5項所述之實驗動物保定裝置,其中 * 該第二開口之内周壁與限位件設有可互相螺合之螺紋 • 結構。 ^ —17 — 201234957 7、 依申請專利範圍第1、2、5或6項所述之實驗動物保定 裝置,其中該穿孔係位於該封閉件。 8、 依申請專利範圍第1、2、5或6項所述之實驗動物保定 裝置,其中該中空體之外周壁設有數刻度。 —18 —201234957 • VII. Patent application scope: 1. An experimental animal Baoding device, comprising: a hollow body having a chamber, the chamber having an inlet end, the inlet end being located at one end of the hollow body, and the The inlet end can be closed by a closing member, the other end of the hollow body has an adjusting portion, and the hollow body is further provided with a perforation and the chamber; and a limiting member is coupled to the adjusting portion of the hollow body. The chamber is used to separate the limiting space of a predetermined size. 2. The laboratory animal securing device according to claim 1, wherein the adjusting portion may be a plurality of slots, wherein the number of slots is located outside the hollow body, and the number of slots is along the hollow The axial direction of the body is spaced apart toward the inlet end. 3. The laboratory animal holding device according to claim 2, wherein the number of slots of the adjusting portion is a two-phase corresponding notch penetrating the outer peripheral wall of the hollow body. _ 4. The laboratory animal Baoding device according to claim 1 or 2, wherein the s circumference is further provided with an opening, and the opening is connected to the cavity of the hollow body. The experimental animal holding device according to the invention of claim 2, wherein the adjusting portion forms a second opening, the second opening is in communication with the chamber, and the limiting member is coupled to the second opening . 6. The laboratory animal securing device according to claim 5, wherein the inner peripheral wall of the second opening and the limiting member are provided with a threaded structure that can be screwed to each other. ^ 17 - 201234957 7. The laboratory animal security device of claim 1, 2, 5 or 6, wherein the perforation is located in the closure. 8. The laboratory animal Baoding device according to claim 1, 2, 5 or 6, wherein the outer wall of the hollow body is provided with a plurality of scales. —18 —
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