201231102 六、發明說明： 【發明所屬之技術領域】 尤指一種液體霧化噴射給藥 [_ι] 本案係關於—種給藥裝置 裝置。 I无刖技術】 [0002] [0003] 霧化器係將液«換成大量㈣之電子裝置，利用液滴 之接觸表面積純於㈣較大之原理，被廣泛地使用於 各方面例如·醫療、美容、環境加濕及室内 於電子元件散熱等，而… 叫現7市场上的霧化器主要分為超 音波式及致動式。 -月》閱第® ’其係為f知勒式霧化器之剖面圖談 習知致動讀化以主要包括—腔能、—霧化片u、一 致動元件12 ’其_腔體10具有一入口通道ΗΠ及-容置槽 102 ’而一流體103由入口通道1〇1輸入且容置於容置槽 1〇2中，霧化片n具有複數個噴孔⑴且相對應於容置槽 102設置’其卜習知致動式霧化器】之作動方式係藉由 重力作用使流體103接觸霧化片u，再經由—電壓作⑽ 動致動元件12以造成振動，使得流體1〇3由複數個喷孔 Η 1形成霧化之液滴1 〇 3 ][。 剛請再參閱第-圖，習知致動式霧化器i必須藉由重力作用 ’使流體103下沉與霧化片Η之喷孔ln接觸，方能使流 體103產生霧化現象以形成液滴ί〇3Ι，如此一來便限制 了驾知致動式霧化器〗之霧化方向，使得習知致動式霧化 益1只能單一方向擺置。此外，當腔體10的容置槽102的 内部深度過深，或是霧化片11之喷孔111的孔徑過大，使 100102013 表單編號Α0]01 第4頁/共25頁 1002003618-0 201231102 亦會 流體103容易累積於噴孔⑴的表面上，造成喷孔⑴堵 塞且形成^良的耗現象。再者，當㈣⑽霧化成液滴 1031時，同時會有空氣由霧化片n的複數個噴孔丨丨1進 入腔體10内部，而於容置槽102上方形成氣泡1〇4， 造成習知致動式霧化器丨之霧化現象不穩定。 [〇〇〇5]因此，如何發展一種可改善上述習知技術缺失之霧化系 統並應用於給藥裝置上，為本案迫切需要研發之課題。、 【發明内容】 Q [0006]本案之目的在於提供一種液體霧化噴射給藥裝置，主要 藉由第-泵浦、霧化模組、第二泵浦及儲液單元争接形 成封閉式流體迴路，俾解決習知致動式霧化器必需藉由 重力作用才能使流體霧化喷出，將限制霧化方向以及容 置槽内容易形成氣泡造成霧化現象不穩定等缺失。 [0007]本案之又一目的在於提供一種液體霧化噴射給藥裝置， 藉由調整控制電路板上泵浦驅動1C及霧化模組驅動以 設定值，可控制泵浦之輸出頻率以及霧化模組之噴出時 ® 間，達成定量液體之霧化噴處》 [0008] 一π ^m钓提供一種一 種液體霧化喷射給藥裝置，至少包括：— 禾—泉浦，用 以供應或眺-流體；—霧化模組，係與該第_&浦連 接’並包含-人卩通道…出σ通道以及複數個喷孔， 用以將部份該流體霧化喷出；一儲液單元，係與嗜第一 泵浦及該霧化模組形成一封閉式流體迴路，使該流體持 100102013 續接觸該複數個喷孔並排出氣泡；以及—控制電路板， 系與該第—②浦及該霧化模 表單、編號肌0! 第5頁/共 逆接用从控制該第一系 、.頁 201231102 浦之輸出頻率以及該霧化模組之噴出時間。 [0009] 為達上述目的，本案之另一較廣義實施態樣為提供一種 液體霧化喷射給藥裝置，至少包括：一第一泵浦，用以 供應或汲取一流體；一霧化模組，係與該第一泵浦連接 ’並包含一腔體、一入口通道、一出口通道以及複數個 喷孔，用以將部份該流體霧化喷出；一多孔性吸收材， 設置於該腔體内，用以吸收該流體；一儲液單元，係與 該第一泵浦及該霧化模組形成一封閉式流體迴路，使該 流體持續接觸該複數個喷孔並排出氣泡；以及一控制電 路板，係與該第一泵浦及該霧化模組連接，用以控制該 第一泵浦之輸出頻率以及該霧化模組之喷出時間。 【實施方式】 [0010] 體現本案特徵與優點的一些典型實施例將在後段的說明 中詳細敘述。應理解的是本案能夠在不同的態樣上具有 各種的變化，其皆不脫離本案的範圍，且其中的說明及 圖式在本質上係當作說明之用，而非用以限制本案。 [0011] 本案係提供一液體霧化噴射給藥裝置，主要包括一霧化 系統以及一控制電路板，該霧化系統包括一霧化模組、 一或二泵浦單元及一儲液單元，其中泵浦單元係用於液 體之供給或汲取以及氣泡之排除，使霧化模組持續穩定 喷出並霧化液體，可避免因喷孔末端聚積水滴及喷孔前 端氣泡聚集造成運作不穩定之情況發生。 [0012] 請參閱第二圖，其係為本案較佳實施例之霧化系統的結 構示意圖。如圖所示，本實施例之霧化系統2主要包括一 第一泵浦21、一霧化模組22及一第二泵浦23，其中霧化 100102013 表單編號A0101 第6頁/共25頁 1002003618-0 201231102 模組22具有一入口通道221及一出口通道222，而第一泵 浦21及第二泵浦23可為一壓電泵浦且採用一進一出的形 式，即分別具有單一入口及單一出口。第一泵浦21之出 口 211以及第二泵浦23之入口 231分別與霧化模組22之入 口通道221及出口通道222相連接，而第—泵浦21的入口 Ο [0013] 212及第二栗浦23的出口 232則與一儲液單元24 (如第五 圖B所示）進行連接，使得第—泵浦21、霧化模組22、第 一栗浦2 3及儲液單元2 4串接形成一封閉式流體迴路，使 流體可在封閉式流體迴路-中循環流動。 當然，前述第一泵浦21、霧化模組22及第二泵浦23之串 接方式不限於第二圖所示之磚闻秦接，其係可配合液體 霧化喷射給藥裝置之空間做適當之龇置調整，例如於第 五圖Β中’第一栗浦21、霧化模組22、第二系浦23及儲液 單元24係大致呈矩形排列。201231102 VI. Description of the invention: [Technical field to which the invention pertains] In particular, a liquid atomized spray administration [_ι] This case relates to a device for administering a drug. I have no flaw technology [0002] [0003] The atomizer is a kind of electronic device that replaces the liquid « into a large number (4), and is widely used in various aspects such as medical treatment by utilizing the principle that the contact surface area of the droplet is pure (4). , beauty, environmental humidification and indoor heat dissipation of electronic components, etc., and the atomizers on the market are mainly divided into ultrasonic and actuated. -月" Read the section ''''''''''''''''''''''''''''''''''''' Having an inlet channel ΗΠ and a accommodating groove 102 ′ and a fluid 103 is input from the inlet channel 1 〇 1 and accommodated in the accommodating groove 1 〇 2, the atomizing sheet n has a plurality of orifices (1) and corresponds to the volume The actuating mode of the groove 102 is to make the fluid 103 contact the atomizing sheet u by gravity, and then actuate the element 12 via the voltage (10) to cause vibration, so that the fluid 1〇 3 by a plurality of orifices Η 1 to form atomized droplets 1 〇 3 ] [. Referring now to the first figure, the conventional actuated atomizer i must be brought into contact with the spray hole ln of the atomizing sheet by the action of gravity, so that the fluid 103 can be atomized to form The droplet 〇3〇, thus limiting the atomization direction of the actuation atomizer, so that the conventional actuation atomization benefit 1 can only be placed in a single direction. In addition, when the internal depth of the accommodating groove 102 of the cavity 10 is too deep, or the aperture of the orifice 111 of the atomizing sheet 11 is too large, the 100102013 form number Α0]01 4th page/total 25 page 1002003618-0 201231102 The fluid 103 is likely to accumulate on the surface of the orifice (1), causing the orifice (1) to clog and form a good consumption phenomenon. Furthermore, when (4) (10) is atomized into the droplets 1031, air is simultaneously entered into the cavity 10 from the plurality of orifices 1 of the atomizing sheet n, and bubbles 1〇4 are formed above the receiving groove 102, resulting in It is known that the atomization phenomenon of the actuated atomizer is unstable. [〇〇〇5] Therefore, how to develop an atomization system which can improve the above-mentioned conventional technology and apply it to a drug delivery device is an urgent need for research and development. [Invention] Q [0006] The purpose of the present invention is to provide a liquid atomized spray drug delivery device, mainly by the first pump, the atomization module, the second pump and the liquid storage unit to form a closed fluid Circuit, 俾Resolve that the conventional actuated atomizer must be atomized and ejected by gravity, which will limit the atomization direction and the bubble formation in the accommodating groove, resulting in instability of the atomization phenomenon. [0007] Another object of the present invention is to provide a liquid atomizing spray drug delivery device, which can control the pump output frequency and atomization by adjusting the pump drive 1C and the atomization module drive on the control circuit board to set values. When the module is sprayed out, the atomized spray of the quantitative liquid is reached. [0008] A π ^m fishing provides a liquid atomized spray delivery device, which at least includes: - Wo-spring, for supplying or licking - a fluid; - an atomization module, connected to the first _ & pu and includes a human channel ... out σ channel and a plurality of orifices for atomizing a portion of the fluid; a stock solution The unit forms a closed fluid circuit with the first pump and the atomizing module, so that the fluid continues to contact the plurality of nozzles and discharges air bubbles by the 100102013; and the control circuit board is associated with the second Pu and the atomization mold form, numbering muscle 0! Page 5 / total reverse connection from the control of the first system, page 201231102 Pu output frequency and the spray time of the atomization module. [0009] In order to achieve the above object, another broad aspect of the present invention provides a liquid atomized spray drug delivery device comprising at least: a first pump for supplying or extracting a fluid; and an atomization module Connected to the first pump and include a cavity, an inlet channel, an outlet channel, and a plurality of orifices for atomizing a portion of the fluid; a porous absorbent material disposed on The chamber is configured to absorb the fluid; a liquid storage unit forms a closed fluid circuit with the first pump and the atomizing module to continuously contact the plurality of nozzle holes and discharge air bubbles; And a control circuit board connected to the first pump and the atomization module for controlling an output frequency of the first pump and a discharge time of the atomization module. [Embodiment] Some exemplary embodiments embodying the features and advantages of the present invention will be described in detail in the following description. It is to be understood that the present invention is capable of various modifications in various aspects, and is not intended to limit the scope of the invention. [0011] The present invention provides a liquid atomized spray drug delivery device, which mainly includes an atomization system and a control circuit board, the atomization system includes an atomization module, one or two pump units, and a liquid storage unit. The pumping unit is used for the supply or extraction of liquid and the elimination of air bubbles, so that the atomization module can continuously spray and atomize the liquid stably, thereby avoiding the unstable operation due to the accumulation of water droplets at the end of the injection hole and the accumulation of bubbles at the front end of the injection hole. The situation happened. [0012] Please refer to the second figure, which is a schematic diagram of the structure of the atomization system of the preferred embodiment of the present invention. As shown in the figure, the atomization system 2 of the present embodiment mainly includes a first pump 21, an atomization module 22, and a second pump 23, wherein the atomization 100102013 Form No. A0101 Page 6 of 25 1002003618-0 201231102 The module 22 has an inlet passage 221 and an outlet passage 222, and the first pump 21 and the second pump 23 can be a piezoelectric pump and adopt a one-in-one-out form, that is, a single inlet respectively. And a single exit. The outlet 211 of the first pump 21 and the inlet 231 of the second pump 23 are respectively connected to the inlet passage 221 and the outlet passage 222 of the atomization module 22, and the inlet 第 [0013] 212 and the first of the pump 21 The outlet 232 of the second Lipu 23 is connected to a liquid storage unit 24 (as shown in FIG. 5B), so that the first pump 21, the atomization module 22, the first Lipu 23 and the liquid storage unit 2 4 is connected in series to form a closed fluid circuit that allows fluid to circulate in the closed fluid circuit. Of course, the connection manner of the first pump 21, the atomization module 22, and the second pump 23 is not limited to the brick connection shown in the second figure, and the space can be matched with the liquid atomization spray device. To make appropriate adjustments, for example, in the fifth diagram, the first Lipu 21, the atomization module 22, the second system 23, and the liquid storage unit 24 are arranged in a substantially rectangular shape.
[0014] G 在第二圖所示實施例中’霧化模粗22之入口通道221及出 口通道222分別連接一個泵滿，其中，與入口通道221連 接之第一泵浦21係作為一供應泵浦，用以供應流體至霧 化模組22，而與出口通道222連接之第二泵浦23則作為一 汲取泵浦，用以汲取液體及吸出氣泡。而在—實施例中 ，霧化模組22僅在其出口通道222連接一個汲取泵浦，用 以汲取液體及吸出氣泡。又，在另一實施例令，霧化模 組22僅在其人口通道221連接—個供麻浦，用以供應流 體至霧化模組22。而無論霧化模組22係僅連接一個供應 泵浦或汲取泵浦，或是同時連接兩個泵浦，皆可透過流 體管路配置將泵浦流率設定於適當值，以達成持續穩定 100102013 表單編號Α0101 第7頁/共25頁 1002003618-0 201231102 霧化噴液。 [0015] [0016] [0017] °月參閱第三圖A，其係為第二圖所示之霧化模組之分解結 構不意圖，如圖所示，本案之霧化模組22可包括一電路 單元220、一蓋體223、一腔體224、一霧化單元225、一 致動tl件226、一底座227以及複數個密封元件228與229 ，務化模組22主要藉由依序將電路單元22〇、蓋體223、 饴封元件228、腔體224、密封元件229、霧化單元225、 致動元件225以及底座227相對應堆疊設置’以完成組裝 〇 睛參閱第三圖B並配合第三圖A，其中第三圖B係為第三圖 A所示之蓋體之背面結構示意圖，如鷗所示，本案之蓋體 223可包含一第一出口 2231及一第一入© 2232，其中入 口通道221與出口通道222分別與第一出口 2231與第一入 口 2232相連通，此外’蓋體223具有分別環繞第一出口 2231及第一入口 2232之凹槽2233及2234，用以提供一 圓環狀之密封元件2 2 8a及2 2 8b依照其相對應之大小分別 設置於凹槽2233及2234内。 請參閱第三圖C並配合第三圖A，其中第三圖C係為第三圖 A所述之腔體之背面結構示意圖，如圖所示，本案之腔體 224可包含一容置槽2241、一第一通孔2242及一第二通 孔2243，如第三圖A所示，腔體224更具有凹槽2244及 2245分別環繞於第一通孔2242及第二通孔2243設置，用 以提供一圓環狀之密封元件228c及228d依照其相對應之 大小分別設置於凹槽2244及2245内，如此一來，藉由密 封元件228a及228b與密封元件228c及228d將可使蓋體 100102013 表單編號A0101 第8頁/共25頁 1002003618-0 201231102 [0018] [0019] Ο [0020][0014] G In the embodiment shown in the second embodiment, the inlet channel 221 and the outlet channel 222 of the atomizing mold 22 are respectively connected to a pump full, wherein the first pump 21 connected to the inlet channel 221 serves as a supply. The pump is used to supply fluid to the atomization module 22, and the second pump 23 connected to the outlet passage 222 acts as a pump for pumping liquid and sucking out air bubbles. In the embodiment, the atomizing module 22 is connected to a pumping pump only at its outlet passage 222 for drawing liquid and sucking out air bubbles. Further, in another embodiment, the atomizing module 22 is connected to only one of its population passages 221 for supplying the fluid to the atomizing module 22. Regardless of whether the atomization module 22 is connected to only one supply pump or pump, or two pumps at the same time, the pump flow rate can be set to an appropriate value through the fluid line configuration to achieve continuous stability 100102013 Form No. 1010101 Page 7 of 251002003618-0 201231102 Atomized spray. [0017] [0017] [0017] ° month refers to the third figure A, which is the decomposition structure of the atomization module shown in the second figure is not intended, as shown, the atomization module 22 of the present case may include a circuit unit 220, a cover 223, a cavity 224, an atomization unit 225, a constant tl member 226, a base 227 and a plurality of sealing elements 228 and 229, the processing module 22 mainly by sequentially The unit 22A, the cover 223, the sealing element 228, the cavity 224, the sealing element 229, the atomizing unit 225, the actuating element 225, and the base 227 are arranged in a stack to complete the assembly. The third figure A, wherein the third figure B is the back structure of the cover body shown in the third figure A, as shown by the gull, the cover body 223 of the present case may include a first outlet 2231 and a first inlet 2232. The inlet channel 221 and the outlet channel 222 are respectively in communication with the first outlet 2231 and the first inlet 2232. Further, the cover 223 has grooves 2233 and 2234 respectively surrounding the first outlet 2231 and the first inlet 2232 for providing a ring-shaped sealing member 2 2 8a and 2 2 8b according to their corresponding size A groove disposed within 2234 and 2233. Please refer to the third figure C and cooperate with the third figure A, wherein the third figure C is a schematic view of the back structure of the cavity shown in the third figure A. As shown, the cavity 224 of the present case can include a receiving groove. 2241, a first through hole 2242 and a second through hole 2243. As shown in FIG. 3A, the cavity 224 further has grooves 2244 and 2245 respectively disposed around the first through hole 2242 and the second through hole 2243. The sealing members 228c and 228d for providing an annular shape are respectively disposed in the grooves 2244 and 2245 according to their corresponding sizes, so that the sealing members 228a and 228b and the sealing members 228c and 228d can make the cover body 100102013 Form No. A0101 Page 8 of 25 1002003618-0 201231102 [0018] [0020] [0020]
223與腔體224之間緊密結合，可防止流體外茂。 此外，如第三圖C所示，腔體224更具有一凹槽2245環繞 於各置槽2241之外圍’用以提供一圓環狀之密封元件229 设置於凹槽2246内，使得腔體224與霧化單元225之間可 緊密結合，可防止流體外洩。 6青再參閱第三圖A ’本案之霧化單元225可為一霧化片， 其具有複數個喷孔2251 ’且該複數個噴孔2251係與腔體 224之容置槽2241相對應設置’用以將容置槽2241内部 之流體霧化噴出，而致動元件226可為一環形壓電片，其 係為一環形中空結構且具有一開口 2261，且開口 2261係 與霧化單元225之複數個喷孔2251相對應設置，至於底座 227也具有一開口 2271 ’且闕口P71興致動元件226之開 口 2261以及複數個喷孔2251相對應設置，使得霧化之液 滴可由開口 2271喷出。 請參閱第四圖A並配合第三圖A及第二圖，其中第四圖a係 為第三圖A所示之霧化模組運衫示意圖，當霧化系統2作 動時’第一栗浦21經由入口通道2 21將流體輸入霧化模組 22内，以使流體經由蓋體223之第一出口 2231以及腔體 224之第一通孔2242傳送至容置槽2241内，待致動元件 226受電路單元220所傳送的電壓觸發而作動，以帶動霧 化單元225振動，進而將容置槽2241内部之部份流體由喷 孔2 2 51喷出’以形成霧化之液滴3 〇 ’而未被霧化之流體 則藉由第二泵浦23的吸力，而由腔體224之第二通孔 2243及蓋體223之第一入口 2232，使未霧化之流體由出 口通道222吸入第二泵浦23，並儲存於儲液單元24中，且 100102013 表單編號A0101 第9頁/共25頁 1002003618-0 201231102 可在霧化系統2下一次作動時再次進入第一泵浦21，如此 不斷地循環且供應流體，可使霧化模組22能持續地霧化 〇 [0021] 另外，當噴孔2251排出已霧化液滴30時，會有空氣由喷 孔225 1進入容置槽2241内部並形成氣泡31，此時，因第 一泵浦21及第二泵浦23的作動，得以連續補充流體進入 封閉式流體迴路，且氣泡31會隨著容置槽2241内的流體 排出腔體224外，如此一來，不但可使得流體能持續地接 觸複數個噴孔2251，更可避免氣泡31於容置槽2241内累 積，進而提高流體霧化現象的穩定性。 [0022] 再者，藉由第一泵浦21及第二泵浦23不斷地補充流體， 並透過調整霧化模組22的霧化頻率及噴出的霧化量、第 一泵浦21之輸出流量及第二泵浦23之吸引流量，使霧化 系統2於翻轉後能夠不受限於重力方向仍然可以正常運作 ，如此一來，即可依照需求進行不同方向之霧化。 [0023] 於一些實施例中，本案於容置槽2241内設置一多孔性吸 收材32 (如第四圖B所示），例如：發泡綿，且多孔性吸 收材32與複數個噴孔2251持續相接觸，主要用來吸附流 體，如此一來，可藉由第一泵浦21及第二泵浦23以定時 定量之方式將流體填補至多孔性吸收材32，使多孔性吸 收材32保持溼潤並持續接觸喷孔2251，以達到讓流體能 穩定地產生霧化的現象。 [0024] 請參閱第五圖A及B，其係為本案液體霧化喷射給藥裝置 之結構示意圖，其中第五圖A為給藥裝置之正面結構圖， 100102013 表單編號A0101 第10頁/共25頁 1002003618-0 201231102 第五圖β為給藥裝置之背面結構透視圖。如圖所示，本案 之液體霧化喷射給藥裝置4係包含一本體41及一握把42， 本體41上具有一開口 411，其係與霧化單元225之複數個 喷孔2251、致動元件226之開口 2261、以及底座227之開 口 2271相對應設置，使得霧化之液滴可由本體之開口 411 噴出。另外，握把42上設置有一開關元件421，其係可供 使用者控制液體霧化噴射給藥裝置4進行給藥。 [0025] Ο ο [0026] 根據本案較佳實施例，液體霧化噴射給藥裝置4主要包括 第一泵浦21、霧化模組22、第二泵浦23、儲液單元以及 控制電路板43，其中第一泵浦21、霧化模組22、第二泵 浦23及儲液單元24係相互串接痗成封閉式流體迴路且 設置於本體41中，而控制電路板43則埤氧於握把42中， 且包括-泵浦驅動積體電路（IC) 431以及_霧化模組驅 動積體電路（1C) 432，其中第一泵浦21及第二泵浦23 係分別透過兩條電線與泵浦驅動1(： 431連接，而霧化模 組22係透過兩條電線與霧化模組驅軔ic 432連接用以 輸入交流電之驅動訊號，藉此駆動第一泵浦21、霧化模 組2 2及第—果浦2 3以進行給藥。 第一泵浦21及第二泵浦23屬於低頻驅動，頻率範圍在 200Hz以内，由於頻率與流率有關，故藉由控制電路板“ 之泵浦驅動1C 431來設定輸出頻率，可使泵浦流率有最 佳匹配，達到霧化單元之噴孔末端不聚積水滴及噴孔前 端不聚集氣泡之功效，而使系統在穩定狀態下運作。另 一方面，霧化模組22屬於高頻驅動，頻率範圍在1〇Μζ至 200kHz之間，且在某些特定頻率會產生霧化噴出情形’ 100102013 表單編號A0I01 第11頁/共25頁 1002003618-0 201231102 這些頻率為共振頻率，故藉由控制電路板之霧化模組驅 動1C 432來設定輸出該頻率之時間，即可達成定量液體 之霧化喷出。 [0027] 本案之液體霧化喷射給藥裝置4係可作為眼睛用藥或口鼻 吸入用藥之給藥裝置，但不以此為限，任何藉由霧化液 體來進行給藥之給藥裝置，皆為本案之液體霧化喷射給 藥裝置4所適用之範圍。 [0028] 综上所述，本案係提供一種液體霧化喷射給藥裝置，藉 由第一泵浦、霧化模組、第二泵浦及儲液單元串接形成 封閉式流體迴路，藉此使流體能將霧化過程中於腔體之 容置槽内所產生之氣泡排出容置槽外，以及可不用再受 限於重力只能單一方向進行霧化，此外，該封閉式流體 迴路使流體可持續接觸霧化單元之複數個喷孔，如此一 來，本案之霧化系統更能大幅的提昇霧化現象之穩定度 。另外，藉由調整控制電路板上泵浦驅動1C及霧化模組 驅動1C之設定值，可控制泵浦之輸出頻率以及霧化模組 之喷出時間，達成定量液體之霧化喷出。 [0029] 由於上述優點係為習知技術所不及者，故本案之液體霧 化喷射給藥裝置極具產業價值，爰依法提出申請。 [0030] 本案得由熟習此技術之人士任施匠思而為諸般修飾，然 皆不脫如附申請專利範圍所欲保護者。 【圖式簡單說明】 [0031] 第一圖：其係為習知致動式霧化器之剖面圖。 [0032] 第二圖：其係為本案較佳實施例之霧化系統的結構示意 100102013 表單編號A0101 第12頁/共25頁 1002003618-0 201231102 圖。 [0033] 第三圖A :其係為第二圖所示之霧化模組分解結構示意圖 [0034] 其係為第三圖A所示之蓋體之背面結構示意圖 [0035] 第三圖C :其係為第三圖A所述之腔體之背面結構示意圖 〇 〇 [0036] 第四圖A :其係為第三圖A所述之霧化模組之去除氣泡之 剖面示意圖。 [0037] 第四圖B :其係為於第四圖A之容置槽中設置多孔性吸收 材之剖面示意圖。 [0038] 第五圖A :其係為本案較佳實施例之液體霧化喷射給藥裝 置的正面結構示意圖。 [0039] 第五圖B :其係為本案較佳實施例之液體霧化喷射給藥裝 置的背面結構透視圖。 【主要元件符號說明】 [0040] 致動式霧化器：1 腔體：10、224 入口通道：101、221 容置槽：102、2241 流體：103 液滴：1031、30 氣泡：104、31 霧化片：11 喷孔·· 111、2251 致動元件：12、226 霧化系統：2 第一泵浦：21 出口 ： 211、232 入口 ： 212、231 表單編號A0101 第13頁/共25頁 1002003618-0 100102013 201231102 霧化模組：22 電路單元：22 0 出口通道：222 蓋體：223 第一出口 ： 2231 第一入口 ： 2232 凹槽：2233、2234 ' 2244、 第一通孔：2242 2245 ' 2246 第二通孔：2243 霧化單元：225 開口 ： 2261、2271、411 底座：227 第二泵浦：23 密封元件：228、228a、228b 、228c 、 228d 、 229 儲液單元：24 多孔性吸收材：32 液體霧化噴射給藥裝置：4 本體：41 握把：42 開關元件：421 控制電路板：43 泵浦驅動積體電路：431 霧化模組驅動積體電路：432 100102013 表單編號A0101 第14頁/共25頁 1002003618-0The tight junction between the 223 and the cavity 224 prevents fluid from escaping. In addition, as shown in FIG. 3C, the cavity 224 further has a recess 2245 surrounding the periphery of each of the slots 2241 to provide a ring-shaped sealing member 229 disposed in the recess 2246, so that the cavity 224 is The atomizing units 225 can be tightly coupled to prevent leakage of fluid. Referring to FIG. 3A, the atomizing unit 225 of the present invention may be an atomizing sheet having a plurality of nozzles 2251' and the plurality of nozzles 2251 are disposed corresponding to the receiving slots 2241 of the cavity 224. 'After atomizing the fluid inside the accommodating groove 2241, the actuating member 226 can be an annular piezoelectric piece, which is an annular hollow structure and has an opening 2261, and the opening 2261 is coupled to the atomizing unit 225. The plurality of nozzles 2251 are correspondingly disposed, and the base 227 also has an opening 2271' and the opening 2261 of the opening P71 and the plurality of nozzles 2251 are correspondingly disposed, so that the atomized droplets can be sprayed by the opening 2271 Out. Please refer to the fourth figure A and cooperate with the third figure A and the second figure, wherein the fourth figure a is the schematic diagram of the atomizing module shirt shown in the third figure A, when the atomizing system 2 is actuated, the first chestnut The pump 21 enters the fluid into the atomization module 22 via the inlet channel 2 21 to transfer the fluid to the accommodating groove 2241 via the first outlet 2231 of the cover 223 and the first through hole 2242 of the cavity 224, to be activated. The component 226 is triggered by the voltage transmitted by the circuit unit 220 to drive the atomization unit 225 to vibrate, and then a part of the fluid inside the accommodating groove 2241 is ejected from the injection hole 2 2 51 to form the atomized droplet 3 The fluid that is not atomized by the suction of the second pump 23 is caused by the second through hole 2243 of the cavity 224 and the first inlet 2232 of the cover 223, so that the un-atomized fluid is discharged from the outlet passage. 222 inhaling the second pump 23 and storing it in the liquid storage unit 24, and 100102013 Form No. A0101 Page 9 / Total 25 pages 1002003618-0 201231102 The first pump 21 can be re-entered when the atomization system 2 is next activated By continuously circulating and supplying fluid, the atomization module 22 can be continuously atomized. [0021] In addition, when the nozzle hole 2251 discharges the atomized droplet 30, air enters the inside of the accommodating groove 2241 from the nozzle hole 2251 and forms a bubble 31. At this time, due to the first pump 21 and the second pump 23 Actuating, continuously replenishing fluid into the closed fluid circuit, and the bubble 31 will discharge out of the cavity 224 along with the fluid in the receiving groove 2241, so that the fluid can continuously contact the plurality of nozzles 2251, and The accumulation of the air bubbles 31 in the accommodating groove 2241 can be avoided, thereby improving the stability of the fluid atomization phenomenon. [0022] Furthermore, the fluid is continuously replenished by the first pump 21 and the second pump 23, and the atomization frequency of the atomization module 22 and the amount of atomization sprayed, and the output of the first pump 21 are adjusted. The flow rate and the suction flow of the second pump 23 enable the atomization system 2 to operate normally without being restricted to the direction of gravity after being turned over, so that atomization in different directions can be performed according to requirements. [0023] In some embodiments, a porous absorbent material 32 (as shown in FIG. 4B) is disposed in the receiving groove 2241, such as a foamed cotton, and the porous absorbent material 32 and a plurality of sprays are provided. The hole 2251 is continuously in contact with each other and is mainly used for adsorbing the fluid. Thus, the first pump 21 and the second pump 23 can be used to fill the porous absorbent material 32 in a timed manner to make the porous absorbent material. 32 keeps wet and continuously contacts the orifice 2251 to achieve a stable atomization of the fluid. [0024] Please refer to FIG. 5A and B, which are structural diagrams of the liquid atomized spray drug delivery device of the present invention, wherein the fifth figure A is the front structure diagram of the drug delivery device, 100102013 Form No. A0101, page 10/total Page 25, 1002003618-0 201231102 Fig. 5 is a perspective view of the back structure of the drug delivery device. As shown in the figure, the liquid atomizing spray device 4 of the present invention comprises a body 41 and a grip 42. The body 41 has an opening 411 which is coupled to the plurality of spray holes 2251 of the atomizing unit 225. The opening 2261 of the member 226 and the opening 2271 of the base 227 are correspondingly disposed such that the atomized droplets can be ejected from the opening 411 of the body. Further, the grip 42 is provided with a switching element 421 for the user to control the liquid atomized ejection administration device 4 for administration. [0025] According to a preferred embodiment of the present invention, the liquid atomized spray drug delivery device 4 mainly includes a first pump 21, an atomization module 22, a second pump 23, a liquid storage unit, and a control circuit board. The first pump 21, the atomizing module 22, the second pump 23, and the liquid storage unit 24 are connected in series to form a closed fluid circuit and disposed in the body 41, and the control circuit board 43 is oxygenated. In the grip 42, and including a pump driving integrated circuit (IC) 431 and an atomizing module driving integrated circuit (1C) 432, wherein the first pump 21 and the second pump 23 are respectively transmitted through two The wire is connected to the pump drive 1 (: 431), and the atomization module 22 is connected to the atomization module drive ic 432 through two wires for inputting the drive signal of the alternating current, thereby pulsing the first pump 21, The atomizing module 2 2 and the first fruit pump 2 3 are administered. The first pump 21 and the second pump 23 are low-frequency driving, and the frequency range is within 200 Hz. Since the frequency is related to the flow rate, by controlling The board "pump drive 1C 431 to set the output frequency, the pump flow rate can be optimally matched to reach the atomization unit The end of the nozzle does not accumulate water droplets and the front end of the nozzle does not collect air bubbles, so that the system operates in a stable state. On the other hand, the atomization module 22 belongs to a high frequency drive, and the frequency ranges from 1 〇Μζ to 200 kHz. And the atomization ejection situation will occur at some specific frequencies' 100102013 Form No. A0I01 Page 11 / Total 25 Page 1002003618-0 201231102 These frequencies are resonance frequencies, so the setting is driven by the atomization module of the control board to drive 1C 432 When the frequency is output, the atomized ejection of the quantitative liquid can be achieved. [0027] The liquid atomized spray administration device 4 of the present invention can be used as an administration device for eye medication or oral and nasal inhalation, but not The drug delivery device for administration by atomizing liquid is applicable to the liquid atomized spray drug delivery device 4 of the present invention. [0028] In summary, the present invention provides a liquid atomization spray. The drug delivery device forms a closed fluid circuit by serially connecting the first pump, the atomization module, the second pump and the liquid storage unit, thereby enabling the fluid to be atomized in the receiving groove of the cavity Produced The bubble is discharged outside the accommodating groove, and can be atomized in a single direction without being restricted by gravity. In addition, the closed fluid circuit enables the fluid to continuously contact the plurality of orifices of the atomizing unit, so that the case The atomization system can greatly improve the stability of the atomization phenomenon. In addition, by adjusting the set value of the pump drive 1C and the atomization module drive 1C on the control circuit board, the output frequency of the pump and the atomization mode can be controlled. The ejection time of the group reaches the atomization ejection of the quantitative liquid. [0029] Since the above advantages are not as far as the prior art, the liquid atomized spray drug delivery device of the present invention is of great industrial value, and the application is made according to law. [0030] The present invention has been modified by those skilled in the art, and is not intended to be protected as claimed. BRIEF DESCRIPTION OF THE DRAWINGS [0031] First figure: It is a cross-sectional view of a conventional actuated atomizer. [0032] Second Figure: It is a schematic diagram of the structure of the atomization system of the preferred embodiment of the present invention. 100102013 Form No. A0101 Page 12 of 25 1002003618-0 201231102 Figure. [0033] FIG. 3 is a schematic view showing the exploded structure of the atomization module shown in FIG. 2 [0034] which is a schematic view of the back structure of the cover shown in FIG. 3A [0035] FIG. 3C The structure of the back surface of the cavity described in the third figure A is a schematic view of the bubble removal of the atomization module described in the third figure A. [0037] FIG. 4B is a schematic cross-sectional view showing the arrangement of a porous absorbent material in the receiving groove of FIG. [0038] Fig. A is a front view showing the structure of the liquid atomized spray administration device of the preferred embodiment of the present invention. [0039] Fig. B is a perspective view showing the back structure of the liquid atomized spray administration device of the preferred embodiment of the present invention. [Main component symbol description] [0040] Actuated atomizer: 1 cavity: 10, 224 inlet channel: 101, 221 accommodating groove: 102, 2241 fluid: 103 droplet: 1031, 30 bubble: 104, 31 Atomizer: 11 orifices · 111, 2251 Actuating components: 12, 226 atomization system: 2 first pump: 21 outlet: 211, 232 entrance: 212, 231 Form No. A0101 Page 13 of 25 1002003618-0 100102013 201231102 Atomization module: 22 Circuit unit: 22 0 Exit channel: 222 Cover: 223 First exit: 2231 First entrance: 2232 Groove: 2233, 2234 ' 2244, First through hole: 2242 2245 ' 2246 Second through hole: 2243 Atomization unit: 225 Opening: 2261, 2271, 411 Base: 227 Second pump: 23 Sealing elements: 228, 228a, 228b, 228c, 228d, 229 Liquid storage unit: 24 Porosity Absorbent: 32 Liquid atomized spray device: 4 Body: 41 Grip: 42 Switching component: 421 Control circuit board: 43 Pump drive integrated circuit: 431 Atomization module drive integrated circuit: 432 100102013 Form number A0101 Page 14 of 25 2003618-0