201231095 六、發明說明： 【發明所屬之技術領域】 本發明一般而言係關於包含水溶性聚合物之固體連續基 質之化妝品組合物，及特定言之係關於可在使用之前利用 水復原而提供液體化妝品之該等化妝品調配物。本發明亦 關於化妝品試用件。 【先前技術】 店面廣泛地使用化妝品試用件以使消費者可在購買之前 評定彩妝品之多種色相（hues)。粉末狀化妝品（諸如眼影或 月思紅）沉積於塑料基材上並藉由保護遮膜覆蓋之個別方塊 區為吾人熟知。然而，包括粉底、睫毛膏、遮瑕膏、唇蜜 (lip glosses)、指甲油等許多化妝品係以液體形式存在及其 本身係不提供該類型之試用件。液體化妝品通常係裝納於 玻璃或塑料容器中以防止溢出及有利於分散施用至皮膚或 其他所預期的區域。該等產品在百貨公司通常以瓶裝（其 係於其中銷售）方式試用及試用件係重複自相同容器取出 供若干位消費者試用。此舉不僅提高衛生顧慮，而且限制 液體化妝品之試用件可分發所透過之管道。例如，目前實 際並非係以郵寄廣告 '雜誌或類似物方式分發。 缺乏一種方便遞送液體化妝品之形式。可溶解膜已用於 其他產業中以遞送液體組份，最常見之實例為通 氣鼻貼。該等類型之產品包括由天然或合成聚合物(諸如 普魯藍（_ulan))組成之水溶性聚合基質。迄今，尚未成 功地以該技術為基礎致力於開發化妝品。 160644.doc 201231095 【發明内容】 因此，本發明之一目標係提供方便於分發化妝品之試用 件之形式，特定言之係指液體化妝品，其可在使用之前或 期間藉由添加水而復原。本發明之另一目標係提供含有_ 或多種諸如著色劑或治療活性劑之化妝品成分之化妝品組 合物，其係分散於水溶性聚合物之基質中，使得該組合物 呈固體形式然可極易藉由水而復原。 根據前述目標及其他，本發明提供適於遞送化妝品組合 物至消費者之新穎形式。在所意欲之化妝品為習知呈液體 形式者之情況下，例如，許多粉底'遮瑕膏、唇蜜及指曱 油之情況，本發明之優點可最為充分地實現。該等液體化 妝品極難如雜誌、目錄及郵寄廣告中之試用件分發給消費 者，且不存有滿意的溶液以在零售商處提供該等液體化妝 品之試用件》然而，本發明並不受限於試用件且於其最寬 態樣上包括可改良化妝品之方便性及可攜帶性之新穎化妝 品形式。 於本發明之一態樣中’提供一種化妝品，包括(但不限 於)化妝品試用件。該化妝品包括由塑料或紙製成之片狀 基材’該基材之至少—部分上沉積有化妝品調配物。通常 地’該化妝品調配物為乾燥的或半固冑，因為任何揮發物 均已在其沉積至基材上之後除去。固體水溶性聚合物之層 形成連續層遍及載有該化妝品調配物之基材之至少一部分 以防止該化妝品調配物發生轉移。或者，該化妝品調配物 可包含乾的水溶性聚合物以使其均勾分散於由該水溶性聚 160644.doc 201231095 口物形成之基質中。於任何一種情況下，乾的水溶性聚合 物之層可藉由薄織物或薄塑料之遮蔽層覆蓋，例如，以在 使用之前保護該組合物。在使用時，消費者將數量足以溶 解該水溶性聚合物及使該液體化妝品復原的水混合至該產 品0 於本發明之另一態樣中，提供一種化妝品試用薄片。該 試用薄片可具有複數個位於呈薄片形式之塑料或紙基材上 之試用區，而化妝品調配物係沉積於各試用區上。於一些 實施例中，該等化妝品調配物於各試用區可不同，因此， 該試用薄片可提供具不同色調或其他光學屬性之多種化妝 品。水溶性聚合基質形成固體層遍及該等試用區之各者上 及可提供保護遮膜來保護該水溶性聚合層。該等化妝品調 配物可使用適量的水復原而製成適於施用至人類外皮（諸 如皮膚、毛髮、睫毛、眉毛及指曱）之液體化妝品組合 物。该基材通常係經打孔或刻痕使得各試用區極易與其他 試用區分開。該等試用薄片可併入於促銷材料（諸如雜誌 或目錄插頁或郵寄廣告）中或可分發至零售部。 亦提供-種製造化妝品試用薄片之方法，該方法包括提 供其上界定有複數個試用區且該等區域之各者上沉積化妝 品調配物之由塑料或紙之薄片製成之基材。通常然非必需 地，該等化妝品調配物於各試用區可不同且可使用複數個 充填頭同時施加至薄片。該等化妝品調配物通常可包含揮 發性組份（諸如水）’及因此該基材可經加熱移除該等揮發 性組份。在該等揮發物自該化妝品組合物移除而留存其殘 160644.doc 201231095 餘物於該基材上之後’通常藉由喷灑將水溶性聚合物之溶 液或分散液施用遍及該等試用區以至少覆蓋該化妝品組合 物之該殘餘物。然後’將該試用薄片加熱至乾燥且該水溶 性聚合物固化成覆蓋該等化妝品調配物之塗層。該基材通 常係經打孔或刻痕使得各試用區極易與其他區域分開。 前述論述僅僅係出示以更明瞭技藝面臨之問題的本質而 既不應以任何方式視為關於先前技術之認可亦不應將本文 中任何參考文獻之引用視為認可該等參考文獻構成本申請 案之「先前技術」。 本發明涉及以新穎形式提供之個人護理產品。如本文所 用術π個人護理產品」係指欲局部施用至人之組合 物。個人護理組合物之實例包括皮膚護理產品、化妝品、 曬知】等力較佳實施例中，該等個人護理產品為化妝 品，及特定言之是指彩妝品。藉由閱讀本說明書明瞭，如 本文所用’術言吾「基本由…組成」係意欲將本 指定材料或步驟及 疋為 貫質不〜響主張本發明之基本及新賴 特徵之彼等β ' 本發明之該等個人鳟理连σ — €理產ασ包括由塑料或紙（纖維素）细 成之基材。該基材採用薄片之 的然基本上為扃孚“ 士 再，“其為一維長形 為扁千，其具有介於約〇·ι至約20密耳（術结 「密耳J係指1/1000英寸）之門$ Ρ # 今 有為約1/2英寸至約⑽度。該薄片可（例如）具 之:;維度，及約-耳至約密耳之習知厚Γ X,片可具有為約i英寸至約12英寸長之—維 I60644.doc 201231095 度」為約1英寸至約12英寸長之第二維度，及約丨密耳至約 之習知厚度。理想地，該薄片具可撓性且對於水及 :上醇⑯&數;^及聚⑦氧流體之其他揮發性溶劑具有足 :一& w致於其在其表面施用液體化妝品時不會變形或 . $壞。亦理想地，該薄片可耐受在爐中加熱至除去揮發性 '劑所需要的溫度’此點取決於與該調配物之特殊性相關 之製程然通常包括在爐中加熱至介於約耽至約100〇c ’ 更通常地’約60。。至約8〇t之間之溫度。 二一些實施例中’局部用調配物係沉積於基材之至少一 /刀上。該局部用調配物可為適用於個人護理者，最常見 係指局部可接受之化妝品。「局部可接受」係指一般而言 視為對於施用至人類外皮（包括頭皮的毛髮、睫毛、眉 ^、面部皮膚、唇、指甲等)具安全性之成分。該等局部 可接受成分可包括(但不限於)著色劑(顏料、色澱及染 料）、填料、成膜劑（耐水性及/或耐油性）、柔軟劑、保濕 劑、乳化劑、增稠劑、流變調節劑、螯合劑、pH調節劑、 皮膚調節劑、活性（治療）劑、防曬劑、香精、防腐劑等。 預期常見於特定局部用調配物中之任何成分係適宜的。 車乂佳之個人濩理產品為化妝品組合物，且特定言之係依 定義包3著色劑之衫妝品。該等著色劑可佔已移除揮發物 後組合物之殘餘物之約5重量％至約99重量％，更通常地， 佔忒殘餘物之約20重量％至約98重量。/。。該等著色劑可為 顏料、色;殿或染料。對該等顏料、色殿或染料之性質基本 無限❹包括列於以引用的方式併人本文中之 I60644.doc 201231095 第 12版（2008)201231095 VI. OBJECTS OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates generally to cosmetic compositions comprising a solid continuous matrix of a water soluble polymer, and in particular to a liquid that can be reconstituted with water prior to use. These cosmetic formulations of cosmetics. The invention also relates to cosmetic trials. [Prior Art] Cosmetic samples are widely used in storefronts to enable consumers to evaluate a variety of colors of cosmetics before purchase. Powdered cosmetics, such as eye shadows or moonlight red, are deposited on plastic substrates and are known by the individual blocks that cover the mask. However, many cosmetics, including foundations, mascaras, concealers, lip glosses, nail varnishes, etc., exist in liquid form and do not provide trials of this type by themselves. Liquid cosmetics are typically contained in glass or plastic containers to prevent spillage and to facilitate dispersion application to the skin or other desired areas. These products are typically used in department stores in the form of bottles (which are sold in them) and the trial parts are repeatedly taken from the same container for trial by several consumers. This not only raises health concerns, but also limits the distribution of liquid cosmetic test pieces through the pipeline. For example, it is currently not distributed by mailing a magazine or magazine. There is a lack of a convenient form to deliver liquid cosmetics. Dissolvable films have been used in other industries to deliver liquid components, the most common example being ventilated nasal patches. These types of products include water soluble polymeric matrices composed of natural or synthetic polymers such as ullan. To date, cosmetics have not been successfully developed based on this technology. SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a form of a test article that facilitates the dispensing of cosmetics, and in particular, a liquid cosmetic which can be reconstituted by the addition of water before or during use. Another object of the present invention is to provide a cosmetic composition comprising _ or a plurality of cosmetic ingredients such as a coloring agent or a therapeutically active agent, which is dispersed in a matrix of a water-soluble polymer, so that the composition is in a solid form and is extremely easy Recovered by water. In accordance with the foregoing objectives and others, the present invention provides novel forms suitable for delivering cosmetic compositions to consumers. The advantages of the present invention are most fully realized in the case where the intended cosmetic is in the form of a liquid form, for example, in the case of many foundations, concealer, lip gloss and finger oil. These liquid cosmetics are extremely difficult to distribute to the consumer as test pieces in magazines, catalogs and mailing advertisements, and there is no satisfactory solution for providing the liquid cosmetics test pieces at the retailer. However, the present invention is not It is limited to the trial piece and includes in its widest aspect a novel cosmetic form which can improve the convenience and portability of the cosmetic. In one aspect of the invention, a cosmetic is provided, including but not limited to a cosmetic trial. The cosmetic comprises a sheet-like substrate made of plastic or paper. At least a portion of the substrate is deposited with a cosmetic formulation. Typically the cosmetic formulation is dry or semi-solid because any volatiles have been removed after they have been deposited onto the substrate. The layer of solid water soluble polymer forms a continuous layer throughout at least a portion of the substrate carrying the cosmetic formulation to prevent transfer of the cosmetic formulation. Alternatively, the cosmetic formulation may comprise a dry water soluble polymer such that it is uniformly dispersed in a matrix formed from the water soluble poly 160644.doc 201231095. In either case, the layer of dry water soluble polymer can be covered by a thin fabric or a thin plastic covering layer, for example, to protect the composition prior to use. In use, the consumer mixes water sufficient to dissolve the water soluble polymer and reconstitute the liquid cosmetic to the product. In another aspect of the invention, a cosmetic trial sheet is provided. The trial sheet may have a plurality of test zones on a plastic or paper substrate in the form of a sheet, and a cosmetic formulation is deposited on each of the test zones. In some embodiments, the cosmetic formulations can be varied in each of the trial zones, and thus, the trial wafer can provide a plurality of cosmetic products having different shades or other optical properties. The water soluble polymeric matrix forms a solid layer throughout each of the test zones and provides a protective mask to protect the water soluble polymeric layer. These cosmetic formulations can be reconstituted with an appropriate amount of water to form a liquid cosmetic composition suitable for application to human skins such as skin, hair, eyelashes, eyebrows and finger lice. The substrate is typically perforated or scored so that each test zone is easily separated from other trials. The trial sheets can be incorporated into promotional materials such as magazine or catalog inserts or mailing advertisements or can be distributed to the retail department. Also provided is a method of making a cosmetic trial sheet, the method comprising providing a substrate made of a sheet of plastic or paper having a plurality of trial zones defined thereon and depositing a cosmetic formulation on each of the zones. It is generally not necessary that the cosmetic formulations be different in each of the trial zones and that a plurality of filling heads can be applied simultaneously to the sheets. Such cosmetic formulations may generally comprise a volatile component (such as water)' and thus the substrate may be heated to remove the volatile components. After the volatiles are removed from the cosmetic composition and the remaining 160644.doc 201231095 remains on the substrate, the solution or dispersion of the water soluble polymer is typically applied throughout the test zone by spraying. To cover at least the residue of the cosmetic composition. The test flakes are then heated to dryness and the water soluble polymer is cured to form a coating covering the cosmetic formulations. The substrate is typically perforated or scored so that each test zone is easily separated from other areas. The foregoing discussion is merely illustrative of the nature of the subject matter of the present invention and should not be considered in any way as an admission of prior art. "Previous technology." The present invention relates to personal care products provided in novel form. As used herein, π personal care product refers to a composition intended for topical administration to a human. Examples of personal care compositions include skin care products, cosmetics, tanning, etc. In preferred embodiments, such personal care products are cosmetic products, and in particular, cosmetic products. By reading this specification, as used herein, the term "comprehensive" is intended to mean that the specified materials or steps are not consistent with the basic and new features of the present invention. The personal cleavage of the present invention, σ - 理 α ασ, comprises a substrate made of plastic or paper (cellulose). The substrate is made of a sheet which is basically a 扃 “ 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士 士1/1000 inch) door $ Ρ # Today is about 1/2 inch to about (10) degrees. The sheet can be (for example): dimension, and about the ear-to-ear mil thicker Γ X, film can be Having a length of from about 1 inch to about 12 inches - dimension I60644.doc 201231095" is a second dimension of from about 1 inch to about 12 inches long, and a conventional thickness of from about mil to about. Desirably, the sheet is flexible and has a sufficient water for the water and the other volatile solvents of the upper alcohol 16& and the poly 7 oxygen fluid: a & w is such that it does not apply liquid cosmetic on its surface. Deformation or . $ bad. Also desirably, the sheet can withstand the temperature required to heat the volatile 'agent' in the furnace. This depends on the process associated with the particularity of the formulation and typically involves heating in a furnace to between about 耽To about 100〇c 'more usually' about 60. . To a temperature of between about 8 〇t. In some embodiments, the topical formulation is deposited on at least one of the substrates. The topical formulation may be suitable for personal care, most commonly a topically acceptable cosmetic. "Partially acceptable" means a component that is generally considered safe for application to human skin (including hair, eyelashes, eyebrows, facial skin, lips, nails, etc.) of the scalp. Such topically acceptable ingredients may include, but are not limited to, colorants (pigments, lakes and dyes), fillers, film formers (water and/or oil resistance), softeners, humectants, emulsifiers, thickening Agents, rheology modifiers, chelating agents, pH adjusting agents, skin conditioning agents, active (therapeutic) agents, sunscreens, perfumes, preservatives, and the like. Any component that is expected to be common in a particular topical formulation is suitable. Che Yujia's personal care products are cosmetic compositions, and the specifics are based on the definition of 3 coloring agent. The colorants may comprise from about 5% to about 99% by weight of the residue of the composition after removal of the volatiles, and more typically from about 20% to about 98% by weight of the hydrazine residue. /. . The colorants may be pigments, colors, temples or dyes. The nature of such pigments, colours or dyes is essentially unlimited and is included in the citation of this article. I60644.doc 201231095 12th edition (2008)
Cosmetic Ingredient Dictionary and Handbook, 中之彼等。 術語「顏料」係、指不溶於所意欲化妝品之水性基中且欲 賦予色Φ或遮蓋力之無機或有機顆粒。較佳之顏料為無機 顏料’諸如金屬氧化物及氫氧化物，特別述及：僅舉幾 例’氧化鎮 '氫氧化鎮、氧化約、氫氧化弼、氧化紹、氣 氧化鋁、氧化鉻、氫氧轉、氧化鈷、氧化鐵' 氫氧化 鐵、氧化錳、氧化鎳、氧化錫、=氧化鈦、氧化錯及氧化 鋅。其他適宜之顏料包括：僅舉幾例，群青藍（即含硫之 矽酸鋁鈉）、普魯士藍（Prussian blue)、錳紫 '絹雲母鐵 氰化鉀、亞鐵氰化鉀、三水合亞鐵氰化鉀、碳酸鎂、碳酸 鈣、氧化矽、滑石、雲母、矽酸鎂、矽酸鋁鎂 '碳黑及諸 如鈦酸鐵、鈦酸鈷及鋁酸鈷之複合氧化物及複合氫氧化 物。為達本發明之目的，包括滑石、碳酸鈣及氧化矽之賦 予遮蓋力之填料亦視為顏料。該等顏料可利用疏水性或親 水性塗料進行表面改質以增進或改變諸如其光學性質、分 放性或與外皮之直接性之一或多種性質，實例包括由 SENSIENTtm Cosmetic Technologies LCW銷售之顏料（其包 括結合至板狀氧化鋁基材及進行三乙氧基辛醯基矽烷表面 處理覆蓋該顆粒約1重量。/。之顏料）之COVALUMINEtm系 列’經疏水改質煙燻氧化矽顆粒之AEROSILTM系列（獲自Cosmetic Ingredient Dictionary and Handbook, among them. The term "pigment" means inorganic or organic particles which are insoluble in the aqueous base of the intended cosmetic and which are intended to impart color Φ or hiding power. Preferred pigments are inorganic pigments such as metal oxides and hydroxides, and are specifically mentioned: oxidized towns, oxidized lanthanum, cerium oxide, oxidized sulphur, aluminum oxide, chromium oxide, hydrogen, to name a few. Oxygen conversion, cobalt oxide, iron oxide 'iron hydroxide, manganese oxide, nickel oxide, tin oxide, titanium oxide, oxidation and zinc oxide. Other suitable pigments include: ultramarine blue (ie, sodium sulphate containing sodium sulphate), Prussian blue, manganese violet 'silica cyanide potassium ferricyanide, potassium ferrocyanide, trihydrate Potassium ferricyanide, magnesium carbonate, calcium carbonate, barium oxide, talc, mica, magnesium silicate, aluminum magnesium citrate 'carbon black and composite oxides such as iron titanate, cobalt titanate and cobalt aluminate and composite hydroxide Things. For the purposes of the present invention, fillers which impart opacity to talc, calcium carbonate and cerium oxide are also considered pigments. The pigments may be surface modified with a hydrophobic or hydrophilic coating to enhance or modify one or more properties such as their optical properties, resolution, or directness to the skin, examples including those sold by SENSINENTm Cosmetic Technologies LCW ( It comprises the COVALUMINEtm series of AEROSILTM series of hydrophobically modified fumed cerium oxide particles bonded to a platy alumina substrate and subjected to surface treatment of triethoxyoctyl decane to cover about 1 weight of the pigment. from
Parsippany N.J.的 Degussa Corporation)，及 AEROXIDE™ ALU C805經疏水改質氧化鋁（獲自Evonik Industries)。 該等局部用調配物亦可單獨或以與顏料及其他著色劑組 160644.doc 201231095 合之形式包含珠光劑。該等珠光劑通常可為鈦酸雲母或氣 氧化絲。該等鈦酸雲母可為白色或有色。有色鈦酸雲母可 具有沉積於顆粒上而改變其色相之氧化鐵或其他顏料。氣 氧化纽珠光劑亦可結合至有色顏料以改變色相，如 CHR0MA_LITE™ 系列（獲自 Englehard C〇rp〇rati〇n (Iselin， NJ.)) ’其為使用硬脂酸鈣結合至氯氧化鉍之有色顏料與 雲母之組合。該珠光劑亦可包括天然珍珠母。產生閃光之 對苯二甲酸酯（例如聚對苯二甲酸乙二酯）亦適宜。 該等局部用調配物亦可包含其他顆粒，包括（但不限於） 高嶺土、耐綸粉末（諸如0rgasolTM)、聚乙烯粉末、鐵氟龍 ™粉末、澱粉、氮化硼、交聯聚甲基丙烯酸酯共聚物粉末 (諸如Polytrap™ (Dow Corning))、聚合微球體（諸如 Expancei™ (Nobel Industries))、聚矽氧樹脂微珠（諸如Degussa Corporation of Parsippany N.J., and AEROXIDETM ALU C805 hydrophobically modified alumina (available from Evonik Industries). These topical formulations may also comprise a pearlizing agent, either alone or in combination with pigments and other colorant groups 160644.doc 201231095. These pearlescent agents can generally be titanate mica or gas oxidized filaments. The titanate mica may be white or colored. Colored titanic acid mica may have iron oxide or other pigments that are deposited on the particles to change their hue. The gas oxidized pearlescent agent can also be incorporated into colored pigments to change the hue, such as the CHR0MA_LITETM series (available from Englehard C〇rp〇rati〇n (Iselin, NJ.)), which is a combination of calcium stearate and bismuth oxychloride. The combination of colored pigments and mica. The pearlescent agent may also include natural mother-of-pearl. It is also suitable to produce a flash terephthalate such as polyethylene terephthalate. The topical formulations may also comprise other particles including, but not limited to, kaolin, nylon powder (such as 0rgasolTM), polyethylene powder, TeflonTM powder, starch, boron nitride, crosslinked polymethacrylic acid. Ester copolymer powder (such as PolytrapTM (Dow Corning)), polymeric microspheres (such as ExpanceiTM (Nobel Industries)), polyoxyxene microbeads (such as
TospearKM，獲自T〇shlba)及其組合。其他適宜之顆粒包括 以商品名 Teg0t0p™ 105 (Degussa/G〇ldschmidtTospearKM, obtained from T〇shlba) and combinations thereof. Other suitable granules are included under the trade name Teg0t0pTM 105 (Degussa/G〇ldschmidt
Corporation)銷售之粒狀矽蠟及以名稱Minc〇rTM 3〇〇 (BASF)銷售之粒狀乙烯基聚合物。 該等局部用調配物可包含非揮發性溶劑及油，包括（但 不限於）脂肪醇、脂肪酸酯、羊毛脂、烴油、聚矽氧油及 其混合物。該局部用調配物亦可包含選自由蠟、水溶性聚 合成膜劑及非水溶性聚合成臈劑組成之群之成膜劑“成 膜劑」已為吾人所熟知且包括在施用於外皮表面時保持可 f、黏性及連續覆蓋遍及外皮之化學品之群。於其他實施 i J中亥等局邛用組合物可不含蝶及/或不含非水溶性聚 I60644.doc 201231095 合成膜劑。然而，於_ 4b杳 ^ ^ ^ 一 例中，該等局部用調配物可 w柔軟劑及保濕劑’於其他實施例中，彼等可不含柔軟 劑及/或保濕劑（包括甘油）。 、 該等局部用調配物可包含— 3或多種揮發性溶劑以助於其 通過加注喷嘴、滴管施用 土材’或採用其他權宜之計分 配調配物至基材之區域上。々 人、 域上°该等揮發性溶劑可為（但不限 〇 3心嗣（例如丙_)、^6醋（例如，乙酸乙醋）、 C 2 - C 6醇（例如，乙醇）、帘太々备， Η矽氧(例如三甲基聚矽氧烷、環 甲矽氧烷五聚物等）、烴（例如 等揮發物係在將局部用奶配二 其合。由於該 你肘匈。丨用凋配物施用至基材之後移除，因 此，其同-性並不具關鍵性。該局部用調配物可施用至基 材之特定區域，或可覆蓋基材之面之大多數部分，或可覆 蓋基材之整個面。 復 在沉積局部用魏物至基材上之後，將其錢移除任何 揮發物。乾燥可於室溫下進行，然較佳係於高溫下進行以 加速揮發物移除。通常地，乾燥係在對流爐令於介於約 3〇。(：至約12〇。(：之間，更通常介於約咐至約㈣之間及 較佳介於約6(TC至約8〇t之間之溫度下進行。乾燥係進行 歷時-段足以實質移除該等揮發物並令該調配物於該基材 上變成固體或半固體殘餘物之時間。 然後，將水溶性聚合物之層沉積遍及基材之至少一部分 (包括其上沉積局部用調配物之殘餘物之部分術語「水 溶性聚合物」包括具有25它時測得為至少0.1克/公升 (g/L)’然較佳為至少1 〇 g/L之溶解度之聚合物。該水溶性 160644.doc 201231095 聚合物應為局部可接受的，因為彼等欲最終溶解並併入施 用至人類外皮之最終調配物中。 忒等水溶性聚合物可為合成聚合物、天然聚合物或源自 天然聚合物之經改質聚合物。代表性水溶性聚合物包括小 麥或大豆蛋白；角蛋白水解產物及磺酸角蛋白；酪蛋白； 白蛋白；瓊脂糖；膠原蛋白；榖蛋白；胰高血糖素；麩 質；玉米醇溶蛋白；明膠及其衍生物：源自幾丁質或源自 甲殼素之聚合物’諸如陰離子、陽離子、兩性或非離子幾 丁質或甲喊素聚合物；聚醣聚合物，諸如以纖維素為主之 聚合物，例如乙酸纖維素、醋酸麩酸纖維素、羥乙基纖維 素、羥丙基纖維素、羥曱基纖維素、甲基纖維素、乙基羥 乙基纖維素、羥丙基甲基纖維素、麩酸羥丙基甲基纖維 素、羧甲基纖維素及季鹼化纖維素衍生物、澱粉及其衍生 物、直鍵澱粉'高直鍵澱粉、羥丙基化高直鏈戮粉及葡聚 糖’·丙烯酸系聚合物或共聚物，諸如聚丙烯酸酯、聚甲基 丙烯酸酯及其共聚物；丙烯醯胺’諸如聚（2_丙稀醯胺基· 2-甲基-1-丙磺酸）；乙烯基聚合物，諸如聚乙烯吡咯啶酮 及交聯聚維酮、曱基乙烯基醚之共聚物及馬來酸野之共聚 物、乙酸乙烯酯與巴豆酸之共聚物、乙烯吡咯咬酮之共聚 物及乙酸乙烯酯之共聚物、乙烯吡咯啶酮與己内醯胺之共 聚物及聚乙烯醇；植物膠及其他天然水膠體，諸如阿拉伯 膠、瓜爾膠、黃蓍膠、三仙膠及衍生物或刺梧桐樹勝、，躁 酸鹽（諸如藻酸鈉）、角又菜膠、果膠、石蓴膠聚糖（ulvane) 及其他海藻膠體、普魯藍、甘露聚糖及半乳甘露聚糖、葡甘 160644.doc 201231095 露聚糖；黏多醣，包括葡萄糖胺聚糖（glycoaminoglycans)、 玻尿酸及其衍生物及硫酸軟骨素；蟲膠；山達樹膠；達瑪 樹脂（dammar resin);攬香樹膠（e】emi gum);柯巴樹脂 (copal resin),己内酼胺，泊洛沙姆（p〇i〇xamer);水溶性 峨’及其混合物及/或衍生物。 可特別述及經改質纖維素 '聚丙烯酸及共聚物、聚丙烯 醯胺、聚乙烯醇及共聚物、乙烯醇/乙酸乙烯酯共聚物、 聚乙烯吡咯啶酮、明膠、普魯藍、瓜爾膠、三仙膠、金合 歡膠、聚環氧乙烷、天然或合成水凝膠及其組合。較佳 地，該水溶性聚合物包括纖維素系，諸如纖維素酯，纖維 素之烷基醚，纖維素之羥基烷基醚，及纖維素之羧烷基 醚。可特別述及乙酸纖維素、三乙酸纖維素、醋酸麵酸纖 維素、經甲基纖維素、g乙基纖維素、㈣基纖維素、甲 基纖維素、乙基經基乙基纖維素、經乙基甲基纖維素、經 丙基甲基纖維素、㈣㈣基甲基纖維素1甲基纖維 素、季驗化纖維素衍生物及其組合。於_實施例中，該水 溶性聚合物為以纖維素喊為主之聚合物、聚環氧乙烧或並 混合物。於-實施财’該水溶性聚合物為甲基纖維辛、、 經丙基甲基纖維素、窥乙基纖維素 '陽離子經乙基纖維 素、經疏水改質之羥乙某總本 基，義維素或經％離子疏水改質之羥 乙基纖維素中之至少一者。 該水溶性聚合物較佳係溶解或分散於適宜之揮發性 中以幫助施用至基材。該揮發性溶劑可為可溶解或分散t 水溶性聚合物之任何溶劑，誠為乾燥之後的殘餘量^ 160644.doc •12· 201231095 : 溶:可一、 i直鍵或支鏈醇，包括甲醇、乙醇、二乙 醇，、諸如丙酮或甲基乙基酮、…=、異丙醇及丁 氧烷；烴；甲苯啫如乙酸乙醋；矽 四氫咳喊.奋 甲基甲酿胺；二甲亞石風； ，-氣甲烷或氣仿；及其組合。較佳地， 為水性的且可包括水或基 非係有意地以可測量影他溶劑並 ’s /合齊丨系統之4氣壓或閃點之含量 添加。 一旦溶解或分散於揮發性溶劑中，該水溶性聚合物即佔 該組合之總重量之約0.1%至約95%，更通常佔約1〇重量％ 至約7 0重量％。 亦可將其他試劑添加於水溶性聚合物之分散液或溶液來 調整所得基質之特徵，諸如其硬度或溶解時間。適宜之增 稠劑包括述於Yu等人之美國專利公開案第2〇1〇/〇2〇4341號 中之彼等，該案之揭示内容係以引用的方式併入。其中包 括（但不限於）羧乙烯基聚合物（諸如以名稱CARBOPOL及 PEMULEN(INCI名稱：丙烯酸酯/丙烯酸c1(N3()烷酯交聯聚 合物；獲自Noveon)銷售之產品），聚丙烯酸酯&聚甲基丙 烯酸酯（諸如以名稱LUBRAJEL及NORGEL(獲自Guardian) 或HISPAGEL(獲自Hispano Chimica)銷售之產品），聚丙稀 醯胺，及聚丙烯酸鈉/二曱聚矽氧烷/環五矽氧烷/十三烷醇 聚醚-6/PEG-PPG-18/18二甲聚矽氧烷，聚丙烯醯胺（例如， 160644.doc •13- 201231095 聚丙烯醯胺/C 13-Cl 4異烧煙）/月桂醇聚崎-72-丙稀醢胺基-2-曱基丙確酸聚合物及共聚物’以Clariant (INCI名稱：聚 丙烯醯基二甲基牛磺酸銨）銷售之聚丙烯醯胺基-2-曱基 丙磺酸），丙烯醯胺與AMPS之乳化交聯陰離子共聚物（諸 如以名稱SEPIGEL 305 (INCI名稱：聚丙烯醞胺/C13-14異 烧烴/月桂醇聚謎-7 ;獲自Seppic)及以名稱SIMULGEL 600 (INCI名稱：丙烯醯胺/丙烯醯基二曱基牛磺酸鈉共聚物/異 十六烷/聚山梨醇酯80;獲自Seppic)銷售之彼等），聚醣生 物聚合物（例如三仙膠、瓜爾膠、角豆樹膠、金合歡膠、 硬葡聚糖、幾丁質及曱殼素衍生物、角叉菜膠、結蘭膠、 藻酸鹽、澱粉）、締合聚合物、締合聚胺基甲酸酯、包括 至少2條含6至3 0個碳原子之烴基親油鏈（以親水順序分開） 之共聚物，諸如以名稱SERAD FX1010、SERAD FX1100 及 SERAD FX1035 (獲自 Huls America)，RHEOLATE 255、 RHEOLATE 278及RHEOLATE 244 (INCI名稱：聚醚-脲-聚 胺基曱酸酯；獲自 Rheox)、DW 1206F、DW 1206J、DW 1206B、DW 1206G 及 ACRYSOL RM 2020 (獲自 Rohm &Granular waxes sold by Corporation) and granular vinyl polymers sold under the name Minc〇rTM 3® (BASF). Such topical formulations may contain non-volatile solvents and oils including, but not limited to, fatty alcohols, fatty acid esters, lanolin, hydrocarbon oils, polyoxyxides, and mixtures thereof. The topical formulation may also comprise a film former "film former" selected from the group consisting of waxes, water-soluble polymeric film formers, and water-insoluble polymeric film-forming agents. It is well known and included in the application to the skin surface. Maintain a group of chemicals that can be f, viscous, and continuously covered throughout the skin. In other implementations, the composition of the composition can be free of butterflies and/or water-insoluble poly-I60644.doc 201231095 synthetic film. However, in the case of _ 4b 杳 ^ ^ ^ , the topical formulations may be softeners and humectants. In other embodiments, they may be free of softening agents and/or humectants (including glycerin). These topical formulations may contain -3 or more volatile solvents to aid in the application of the soil by means of a filling nozzle, a dropper, or other expedients to distribute the formulation to the area of the substrate. The volatile solvent may be (but not limited to, 3 嗣 (eg, propylene), 1-6 vinegar (eg, ethyl acetate), C 2 -C 6 alcohol (eg, ethanol), The curtain is too prepared, such as oxygen (such as trimethyl polysiloxane, cyclomethoxine pentamer, etc.), hydrocarbons (such as the equivalence of the volatiles in the topical milk. Because of the elbow Hungarian. The extract is removed after application to the substrate, so its homogeneity is not critical. The topical formulation can be applied to a specific area of the substrate, or can cover most of the surface of the substrate. Partially, or covering the entire surface of the substrate. After depositing the topical material on the substrate, the money is removed from any volatiles. Drying can be carried out at room temperature, but preferably at elevated temperatures. Accelerating the removal of volatiles. Typically, the drying is in a convection oven between about 3 Torr. (: to about 12 Torr. (between, more usually between about 咐 to about (4) and preferably between about 6 (at a temperature between TC and about 8 〇t. The drying is carried out for a period of time sufficient to substantially remove the volatiles and to cause the formulation to be on the substrate The time at which the solid or semi-solid residue is formed. Then, the layer of the water-soluble polymer is deposited throughout at least a portion of the substrate (including the portion of the residue on which the topical formulation is deposited, the term "water-soluble polymer" includes 25 It is then measured to be at least 0.1 g/liter (g/L) of a polymer which is preferably at least 1 〇g/L. The water soluble 160644.doc 201231095 polymer should be locally acceptable because They are intended to be finally dissolved and incorporated into the final formulation for application to human skin. Water-soluble polymers such as hydrazine may be synthetic polymers, natural polymers or modified polymers derived from natural polymers. Polymers include wheat or soy protein; keratin hydrolysate and sulfonic acid keratin; casein; albumin; agarose; collagen; prion protein; glucagon; gluten; zein; gelatin and its derivatives Material: a polymer derived from chitin or derived from chitin [such as an anionic, cationic, amphoteric or nonionic chitin or a serotonin polymer; a polysaccharide polymer such as cellulose Polymers such as cellulose acetate, cellulose acetate glutamate, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, methyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl methyl fiber , hydroxypropyl methylcellulose glutamate, carboxymethyl cellulose and quaternized cellulose derivatives, starch and its derivatives, direct bond starch 'high straight starch, hydroxypropylated high linear strontium powder and dextran' Acrylic polymers or copolymers such as polyacrylates, polymethacrylates and copolymers thereof; acrylamides such as poly(2-acrylic-2-methyl-1-propanesulfonic acid) Vinyl polymers, such as polyvinylpyrrolidone and crospovidone, copolymers of mercapto vinyl ether and copolymers of maleic acid, copolymers of vinyl acetate and crotonic acid, vinylpyrrolidone Copolymer and copolymer of vinyl acetate, copolymer of vinylpyrrolidone and caprolactam and polyvinyl alcohol; vegetable gum and other natural hydrocolloids, such as gum arabic, guar gum, tragacanth, three cents Gum and derivatives or paulownia tree, citrate Such as sodium alginate), horn gum, pectin, pectin, ulvane and other seaweed colloids, pullulan, mannan and galactomannan, glucomannol 160644.doc 201231095 Mucopolysaccharides, including glycosaminoglycans, hyaluronic acid and its derivatives, and chondroitin sulfate; shellac; sada gum; dammar resin; scented gum (e) emi gum; Copal resin, caprolactam, poloxamer (p〇i〇xamer); water-soluble oxime' and mixtures and/or derivatives thereof. Special mention may be made of modified cellulose 'polyacrylic acid and copolymers, polypropylene decylamine, polyvinyl alcohol and copolymers, vinyl alcohol/vinyl acetate copolymer, polyvinylpyrrolidone, gelatin, pullulan, melon Gum, Sanxian gum, acacia gum, polyethylene oxide, natural or synthetic hydrogels, and combinations thereof. Preferably, the water soluble polymer comprises a cellulose system such as a cellulose ester, an alkyl ether of cellulose, a hydroxyalkyl ether of cellulose, and a carboxyalkyl ether of cellulose. Mention may be made, in particular, of cellulose acetate, cellulose triacetate, cellulose acetate acetonate, methyl cellulose, g ethyl cellulose, (tetra) cellulose, methyl cellulose, ethyl vinyl ethyl cellulose, Ethylmethylcellulose, propylmethylcellulose, (tetra)(tetra)methylcellulose 1 methylcellulose, quaternary cellulose derivatives, and combinations thereof. In the embodiment, the water-soluble polymer is a cellulose-based polymer, a polyethylene oxide or a mixture thereof. - The implementation of the water-soluble polymer is methyl fiber octane, propyl methyl cellulose, pevine ethyl cellulose 'cation via ethyl cellulose, hydrophobically modified hydroxyethyl total base, At least one of oryzanol or hydroxyethyl cellulose hydrolytically modified with % ion. Preferably, the water soluble polymer is dissolved or dispersed in a suitable volatility to aid application to the substrate. The volatile solvent may be any solvent which can dissolve or disperse the water-soluble polymer, and is the residual amount after drying. ^ 160644.doc • 12· 201231095 : Solubility: can be a direct or branched chain alcohol, including methanol , ethanol, diethanol, such as acetone or methyl ethyl ketone, ... =, isopropanol and butane; hydrocarbon; toluene such as ethyl acetate; 矽 tetrahydrocry cray. A stone wind; , - gas methane or gas imitation; and combinations thereof. Preferably, it is aqueous and may include water or a base which is intentionally added at a level of 4 rpm or flash point of the measurable solvent and 's / 丨 system. Once dissolved or dispersed in a volatile solvent, the water soluble polymer comprises from about 0.1% to about 95%, more typically from about 1% to about 70% by weight, based on the total weight of the combination. Other agents may also be added to the dispersion or solution of the water soluble polymer to adjust the characteristics of the resulting substrate, such as its hardness or dissolution time. Suitable thickening agents include those described in U.S. Patent Publication No. 2, the entire disclosure of which is incorporated herein by reference. These include, but are not limited to, carboxyvinyl polymers (such as those sold under the names CARBOPOL and PEMULEN (INCI name: Acrylate/Acrylic C1 (N3() alkylate crosspolymer; available from Noveon)), Polyacrylic acid Ester & polymethacrylate (such as the product sold under the names LUBRAJEL and NORGEL (from Guardian) or HISPAGEL (from Hispano Chimica)), polyacrylamide, and sodium polyacrylate/dioxane/ Cyclopentaoxane/tridecyl ether-6/PEG-PPG-18/18 dimethyl polyoxane, polypropylene decylamine (eg, 160644.doc • 13- 201231095 polyacrylamide/C 13 -Cl 4 iso-smoke) / lauryl alcohol poly-sodium-72-acrylamido-2-mercapto-propionic acid polymer and copolymer 'with Clariant (INCI name: polypropylene decyl dimethyl taurine Ammonium) sold by acrylamido-2-mercaptopropanesulfonic acid), an emulsified crosslinked anionic copolymer of acrylamide and AMPS (such as the name SEPIGEL 305 (INCI name: Polyacrylamide/C13-14) Charcoal/lauryl alcohol poly-mystery-7; obtained from Seppic) and under the name SIMULGEL 600 (INCI name: acrylamide/acryloyl fluorenyl sulfonate Sodium Copolymer/Isohexadecane/Polysorbate 80; obtained from Seppic), glycan biopolymers (eg, Sanxian, Guar, Carob, Acacia, Hard Portuguese) Glycans, chitin and chitin derivatives, carrageenan, gluten, alginate, starch), associative polymers, associative polyurethanes, including at least 2 containing 6 to a copolymer of 30 carbon atoms of a hydrocarbyl oleophilic chain (separated in a hydrophilic order), such as under the names SERAD FX1010, SERAD FX1100 and SERAD FX1035 (available from Huls America), RHEOLATE 255, RHEOLATE 278 and RHEOLATE 244 (INCI name: Polyether-urea-polyamino phthalate; available from Rheox), DW 1206F, DW 1206J, DW 1206B, DW 1206G, and ACRYSOL RM 2020 (available from Rohm &
Haas)銷售之聚胺基甲酸酯，水溶性乙烯基聚合物，及纖 維素（諸如微晶纖維素、羧曱基纖維素、羥曱基纖維素及 經丙基纖維素）。假若存在，增稠劑通常可佔該水溶性成 膜聚合物重量之約〇·〇 1重量％至約5〇重量。/❶。荷荷葩水合 物（其為荷荷葩醇、荷荷葩油酸鉀及丁二醇之混合物，獲 自Desert Whale)提供膜良好之美觀性質。 亦可添加可塑劑，包括（但不限於）：三烷基檸檬酸酯、 160644.doc 201231095 僅舉幾：’甘油、丙二醇、山梨糖醇、二 400)、單#戊-恥、辛乙二醇、聚乙二醇(諸如PEG 一醣及聚環氧乙烷。丙二醇為較佳之可塑 =假若存在’可塑劑通常可佔該水溶性成膜聚合= 之約0·01重量❶/〇至約50重量％。 ^配合所意欲化妝品之任何其他組份亦可添加至水溶 ^溶液或懸浮液’但限制條件為該等額外組份對藉此 固體膜無不利影響。其中包括（但不限於）列於％等 人之美國專利公開案第2〇1〇/〇期41號之去膠黏劑、調節 劑及柔軟劑中之任-者，該案之揭示内容係以弓^用的方式 併入；以及著色劑、防腐劑⑽如贈叫、_節劑、還 原劑、香精、發泡劑、曬黑劑、脫毛劑、香料、收敛劑、 防腐劑（a—㈣、除臭劑、止汗劑、驅蟲劑、防曬劑、 防喊霜、漂白劑及亮白劑、去頭屑劑、黏著劑、亮光劑、 強化劑、填料、障壁材料及殺生物劑。 於另I實施例中，該局部用調配物不是直接沉積至基材 上而疋均勻分散於水溶性聚合物基質中。於該情況下， 該局部用調配物可在將其喷灌或以其他方式將其施用至該 基材之前與該水溶性聚合物之溶液或懸浮液組合。 然後’將視需要包含增稠劑、可塑劑等之水溶性聚合物 之該懸浮液或溶液施用至對其刻局部用靠物之該基材 之表面。施用應至少覆i载有局部用調配物之該殘餘物之 »亥基材之。卩分，然可覆蓋該側面上該基板之整個表面。 該溶液或懸浮液可洗鑄、塗佈、喷、擠出、包覆或以其 I60644.doc 15 201231095 他方式（例如’藉由將該基材浸潰於該溶液或懸浮液中）沉 積至该表面上。於較佳操作中，該溶液或懸浮液係、藉由加 磨喷嘴錢至該表面上。所施狀材料的量應足以在硬化 時提供厚度為約密耳至約2()密耳之膜。 在已施加水溶性聚合物之後，揮發物係藉由蒸發或藉由 加熱移除以使该水溶性聚合物固化成固體膜覆蓋基材，以 致於局部用調配物之殘餘物夾於該基材與該水溶性聚合膜 之間。該等揮發物較佳藉由加熱至足以促進揮發物移除但 足夠低以防該基材或膜損壞之溫度而移除。於一個實施例 中’該薄片係加熱至介於約40t至約150〇c之間，較佳介 於約5〇t至約m：之間，更佳約㈣至約8(rc(例如〜7n：) 之溫度。 可將織物或塑料之遮蔽層置於該水溶性聚合膜之頂部以 保護該膜直到該產品準備使用為止，然而其係嚴格選用。 若使用，該遮蔽層應可輕易自該水溶性聚合物層剝落且理 想上應透明以可見化妝品之色彩。 在使用時，消費者可將水加至水溶性膜，例如藉由逐滴 施加水至該表面，以溶解該膜。根據揭示於Yu等人之美國 專利公開案第20 10/0204341號中之溶解測試，該膜應可在 小於30秒，較佳小於20秒，更佳小於1〇秒内溶解，該案之 揭示内容係以引用的方式併入。使用者可徹底混合水與膜 以溶解該膜及用水與膜均質化局部用調配物之殘餘物。以 该方式，該局部用調配物復原為適於局部施用至人類外皮 之液體調配物。該組合物可利用手指、施料器或類似物混 160644.doc •16· 201231095 合。通常地’該局部用調配物 是液體化妝品，包括复原形成化妝口口，特別 4t (不限於)粉底、遮瑕膏、睫毛餐 指甲油或唇蜜者。 睫毛膏、 於一個較佳實施例中， 或珠光劑…於’用調配物為包含顏料及/ 及琛九劑之叔底。於一個實 斗且,Γ j τ，5亥溥片可為1至10英 寸長，1至10英寸寬，與介 兴 約20密耳間之厚度，及 其上可具有0.1密耳至約20密 久 密耳厚度之水溶性聚合物層， 及視需要可提供添加丨至約25 D凋水至該表面，更通常約1至 _，較佳約1至約5滴水，以溶解該膜之使用說明。咳 化妝品混合至均勾為止’然後施用至臉部皮膚。 人 於本發明之—個實施例中，該個人護理產品為適於試用 不同化妝品(例如不同色調、色相、亮度或其他光學性質 之化妝)之薄片。该薄片可劃分成多個不同預先界定之 試用區:其可藉由在該基材中刻痕或打孔而互相分離。然 而’該薄片並非必須刻痕或打孔來界定多個區域。該試用 薄片通常具有如上所述之尺寸’較佳可經適宜尺寸化以包 括於目錄、郵寄廣告或類似物中。該等試用區通常以諸如 具有1至10個方塊區之列及具有i至1〇個方塊區之行之格網 配置，但較常以2至8個方塊區之列及2至8個方塊區之行配 置。 試用薄片可藉由使用不同填充頭個別或同時施用化妝品 組合物之不同色彩/色調至該試用薄片之不同試用區上製 備。然後’可如前述於爐中例如在約7〇°C加熱該薄片，以 乾燥出液體化妝品中之揮發物，及於該基材上留下該化妝 I60644.doc 17 201231095 品之固體或半固體沉積物。或者，該化妝品可使用已知技 術印刷至。亥基材上。然後，將水溶性聚合物層沉積（通常 藉由嗔:簏)於該薄月上液體化妝品之殘餘物上。然後，可 加熱該薄片以移除揮發性溶劑及乾燥該等水溶性聚合物成 硬膜。 >本發明之試用薄片有利於直接銷f，藉由提供該等試用 薄片於型錄中及提供粉底色調之多個方塊區供消費者測 試、挑選及選擇。該試用薄片亦提供售貨員在店内或在家 庭銷售拜訪期間將試樣分發至消費者之機會。該等試用薄 片可散置於雜誌及其他期刊中及/或可附接於雜誌中以允 許購貝者自雜14撕下及試用該薄片上的不同色調/色彩試 樣。以另一方式，該試用薄片可併入發送給消費者、用戶 及T由售Μ散佈之型錄中。該試用薄片允許消費者在 購買之前試用不同的色調及色彩。該薄片係可攜帶的及因 此4費者亦可在旅行時或隨時隨地以「潤色」方式使用。 在提ί、各具有不同色調之多個區段之情況下，消費者亦有 機會藉由摻合二或多種色調定製色調。 於一較佳實施例中，該4固人護S組合物為液體化妝品， 及更佳為適於施用至臉部或皮膚之化妝品粉底或乳霜，或 唇蜜或唇彩組合物。該液體化妝品通常可以不同色調及色 也之陣列提供於試用薄片上。該等不同色彩係經由一或多 種顏料、珠光劑、色澱或染料之内含物顯影。 於較佳實施例中’該試用薄片可經打孔成複數個其各 者上均沉積化妝品試用件之試用方塊區或象限。該薄片之 160644.doc 201231095 該打孔有利於將所預期的試用件自該整張薄片撕下。然後 該化妝品試用件可自襯片基材剝離及利用水溶解或復原或 可將水直接添加至該薄片並於該薄片上原位混合。 該等化妝品可採用適於施用至皮膚、唇、毛髮、睫毛及/ 或眉毛之任何半固體或液體產品形式，諸如乳霜、軟膏、 溶液、膏、髮油、凝膠、乳劑或睫毛膏。較佳之產品為粉 底、遮瑕膏、潤膚膏，及口紅及唇蜜。 本發明之組合物可視需要包含通常配合化妝品及個人護 理產品之其他活性及無活性成分，包括（但不限於）賦形 劑、填料、乳化劑、抗氧化劑、表面活性劑、成膜劑、餐 合劑、膠凝劑、增稠劑、柔軟劑、保濕劑、潤膚膏、維生 素、抗壞血酸鈉/磷酸膽固醇酯、礦物質、植物性藥物、 氧雜十一貌 劑、類視色素、激素型化合物、α_經基酸、— — 二酸、α-酮酸、抗分枝桿菌劑、抗真菌劑、抗微生物劑、 抗病毒劑（antiviral)、鎮痛藥、脂類化合物、抗過敏劑、 H1或H2抗組織胺、消炎劑、抗刺激劑、抗贅瘤劑、免疫 系統增強劑、免疫系統抑制劑、防粉刺劑、麻醉劑、防腐 劑、驅蟲劑、皮膚冷卻化合物、皮膚保護劑、皮膚滲透促 進劑、磨砂劑、潤滑劑、香精、著色劑、染色劑、 劑、色素減退劑、防腐劑、穩定劑、醫藥、光穩定劑及其 混合物。 ' 現本發明之特定態樣 以下實例係意以非限制性方式展 【實施方式】 160644.doc •19- 201231095 實例 實例1 化妝品試用薄片之製法 以同時使用不同充殖 、貝之方式使不同色彩/色調之液體 化妝时滴落於試用薄片之不同區域上。 ’中m〇 c加熱該等試用薄片以乾燥出該等液體化 妝品t之所有揮發物。 ㈣等化妝品液滴喷壤水溶性聚合物之厚層以防止該化 妝品轉移至其他表面。 再於爐中加熱試用薄片以乾燥該等喷塗聚合物。 實例2 自試用薄片使用化妝品試用件 消費者選擇適於使用或測試之所期化妝品試用件。假若 係經打孔，則所期試用件可自該薄片被撕下及該 /片上留存的試用件係保留供後來使用。然後利用水 满濕該所期試科使得該試用薄片上之固體變黏。然後， 肖費者可利用其手指自該試用薄片擦栻該化妝品且施用至 臉部或皮膚之所期區域。將啖多弋 將次夕或少的水添加至該化妝品 度。卩影響某些化妝品試用件之色彩強度或覆蓋率程 所有百分比係依重量計，除非另外指明，否 之總重量計。 物 包括引用於本文中之專利申請案及公開案之所有 獻之全文係以引用的方式併入本文中且於該程度上針對於 160644.doc •20- 201231095 所有目的’如同個別公開案或專利或專利申請案係各自明 確及個別地指不以其全文併入本文供參考以實現所有目 的。 熟習此項技術者明瞭’本發明之許多修改及變化可在不 脫離其精神及範圍下進行。述於本文中之特定實施例係僅 僅以實例方式出示，及本發明欲僅受限於隨附中請專利範 圍之術纟吾，以及逾該蓉由古主t 4ι丨tsi α νϋ· 一邊寻甲叫專利範圍所獲授者等效之整個 範圍。 【圖式簡單說明】 圖1繪示根據本發明之一個人護理產品10，其包括一基 材20、一沉積於該基材上之局部用調配物4〇、一覆蓋該等 基材及局部用調配物之水溶性聚合物3〇之固體膜，及一在 水溶性聚合物30之該層上之可移除遮蔽膜5〇。 圖1A為圖1之該個人護理產品j❶之橫截面視圖。 圖2繪示根據本發明之一化妝品試用件100，其包括一具 有界定個別試用區之穿孔170之基材120，各試用區包含化 妝品調配物140A-L，其中之各者可相同或不同，其係沉積 於該基材120上、一覆蓋該等基材及化妝品調配物J40A-L 之水溶性聚合物130之固體膜，及一在水溶性聚合物130之 該層上之可移除遮蔽膜150。 【主要元件符號說明】 20 基材 30 水溶性聚合物 40 局部用調配物 160644.doc -21 - 201231095 50 遮蔽膜 100 化妝品試用件 120 基材 130 水溶性聚合物 140A 化妝品調配物 140B 化妝品調配物 140C 化妝品調配物 MOD 化妝品調配物 140E 化妝品調配物 140F 化妝品調配物 140G 化妝品調配物 140H 化妝品調配物 1401 化妝品調配物 140J 化妝品調配物 140K 化妝品調配物 140L 化妝品調配物 150 遮蔽膜 170 穿孔 -22- 160644.docHaas) sold polyurethanes, water soluble vinyl polymers, and celluloses (such as microcrystalline cellulose, carboxymethyl cellulose, hydroxymethyl cellulose, and propyl cellulose). If present, the thickening agent will generally comprise from about 1% by weight to about 5% by weight based on the weight of the water-soluble film-forming polymer. /❶. The hydrazine hydrate, which is a mixture of decyl alcohol, potassium sulphate and butylene glycol, obtained from Desert Whale, provides good aesthetic properties of the film. Plasticizers may also be added, including (but not limited to): trialkyl citrate, 160644.doc 201231095 to name a few: 'glycerol, propylene glycol, sorbitol, two 400), single # 戊- shame, 辛乙二Alcohol, polyethylene glycol (such as PEG monosaccharide and polyethylene oxide. Propylene glycol is preferred plasticity = if present) plasticizer can usually account for about 0. 01 weight ❶ / 〇 to the water-soluble film forming polymerization = 50% by weight. ^ Any other component of the intended cosmetic may also be added to the water-soluble solution or suspension', but the limitation is that the additional components have no adverse effect on the solid film, including but not limited to The disclosure of the case of the US Patent Publication No. 2〇1〇/〇41 of the US Patent Publication No. 41, the disclosure of which is incorporated by reference. And coloring agents, preservatives (10) such as gifts, _ agents, reducing agents, flavors, foaming agents, tanning agents, depilatory agents, perfumes, astringents, preservatives (a- (four), deodorant, stop Sweat, insect repellent, sunscreen, shatter-resistant cream, bleach and brightener, antidandruff, adhesive , a brightener, a reinforcing agent, a filler, a barrier material, and a biocide. In another embodiment, the topical formulation is not deposited directly onto the substrate but is uniformly dispersed in the water soluble polymer matrix. The topical formulation can be combined with a solution or suspension of the water soluble polymer prior to spraying it or otherwise applying it to the substrate. Then 'will thickeners, plasticizers, etc., as needed. The suspension or solution of the water-soluble polymer is applied to the surface of the substrate to which the topical composition is applied. The application should be at least covered with the substrate of the residue containing the topical formulation. The entire surface of the substrate may be covered on the side. The solution or suspension may be cast, coated, sprayed, extruded, coated or in the form of its I60644.doc 15 201231095 (eg 'by The substrate is impregnated into the solution or suspension and deposited onto the surface. In a preferred operation, the solution or suspension is applied to the surface by grinding the nozzle. The amount of material applied should be sufficient. Providing a thickness of about The ear is about 2 () mil film. After the water-soluble polymer has been applied, the volatiles are removed by evaporation or by heating to solidify the water-soluble polymer into a solid film covering the substrate, so that it is partially The residue of the formulation is sandwiched between the substrate and the water soluble polymeric film. The volatiles are preferably heated to a temperature sufficient to promote volatile removal but low enough to prevent damage to the substrate or film. Removed. In one embodiment, the sheet is heated to between about 40 t and about 150 〇c, preferably between about 5 〇t and about m:, more preferably about (four) to about 8 (rc ( For example, a temperature of ~7n:). A fabric or plastic masking layer can be placed on top of the water-soluble polymeric film to protect the film until the product is ready for use, however it is strictly selected. If used, the masking layer should be It is easily peeled off from the water-soluble polymer layer and ideally should be transparent to reveal the color of the cosmetic. In use, the consumer can add water to the water soluble film, for example by applying water dropwise to the surface to dissolve the film. The film should be soluble in less than 30 seconds, preferably less than 20 seconds, more preferably less than 1 second, according to the dissolution test disclosed in U.S. Patent Publication No. 20 10/0204341 to Yu et al. The content is incorporated by reference. The user can thoroughly mix the water with the membrane to dissolve the membrane and homogenize the residue of the topical formulation with water and membrane. In this manner, the topical formulation reverts to a liquid formulation suitable for topical application to the human rind. The composition can be mixed with fingers, applicators or the like. 160644.doc •16· 201231095. Typically, the topical formulation is a liquid cosmetic comprising reconstitution to form a cosmetic mouth, particularly 4t (not limited to) foundation, concealer, eyelashes, nail polish or lip gloss. The mascara, in a preferred embodiment, or a pearlescent agent, is a tertiary base comprising a pigment and/or a ninth agent. In a real bucket, Γ j τ, 5 溥 溥 can be 1 to 10 inches long, 1 to 10 inches wide, and a thickness of about 20 mils, and can have 0.1 mils to about 20 a water-soluble polymer layer of a dense mil thickness, and optionally added hydrazine to about 25 D with water to the surface, more typically from about 1 to _, preferably from about 1 to about 5 drops of water to dissolve the film Instructions for use. The cough is mixed until it is evenly hooked and then applied to the skin of the face. In one embodiment of the invention, the personal care product is a sheet suitable for trialing different cosmetics, such as makeup of different shades, hue, brightness or other optical properties. The sheet can be divided into a plurality of different pre-defined test zones: they can be separated from one another by scoring or perforating the substrate. However, the sheet does not have to be scored or perforated to define multiple regions. The trial sheet typically has a size as described above. Preferably, it can be suitably sized for inclusion in a catalog, mailing advertisement or the like. The trial zones are typically configured in a grid such as a column having 1 to 10 blocks and rows having i to 1 block, but more often 2 to 8 blocks and 2 to 8 blocks. The configuration of the district. Trial sheets can be prepared by applying different color/hues of the cosmetic composition individually or simultaneously using different filling heads to different test zones of the trial sheet. The sheet can then be heated in a furnace, for example at about 7 ° C, to dry out the volatiles in the liquid cosmetic, and leave the cosmetic I60644.doc 17 201231095 solid or semi-solid on the substrate. Sediment. Alternatively, the cosmetic product can be printed using known techniques. On the substrate. The water soluble polymer layer is then deposited (usually by 嗔: 簏) onto the residue of the liquid cosmetic on the thin month. The sheet can then be heated to remove volatile solvents and to dry the water soluble polymers into a hard film. > The trial sheet of the present invention facilitates direct pin f by providing the test sheets in the catalog and providing a plurality of square regions of the foundation tones for consumer testing, selection and selection. The trial sheet also provides an opportunity for the salesperson to distribute the sample to the consumer during the store or during a home sales visit. Such test patches can be interspersed in magazines and other journals and/or can be attached to magazines to allow the purchaser to tear off and try out different shade/color samples on the sheet. Alternatively, the trial sheet can be incorporated into a catalog that is sent to the consumer, the user, and T by the sold out. The trial sheet allows the consumer to try different shades and colors before purchasing. The sheet is portable and therefore can be used in the "touch" manner when traveling or anytime, anywhere. In the case of multiple sections having different tones, the consumer also has the opportunity to customize the tones by blending two or more tones. In a preferred embodiment, the composition is a liquid cosmetic, and more preferably a cosmetic foundation or cream suitable for application to the face or skin, or a lip gloss or lip gloss composition. The liquid cosmetic product can usually be provided on the trial sheet in an array of different shades and colors. The different colors are developed via the inclusion of one or more pigments, pearlizing agents, lakes or dyes. In the preferred embodiment, the test sheet can be perforated into a plurality of test squares or quadrants in which the cosmetic test pieces are deposited on each of them. The sheet 160644.doc 201231095 The perforation facilitates tearing the intended trial piece from the entire sheet. The cosmetic trial piece can then be peeled from the liner substrate and dissolved or reconstituted with water or water can be added directly to the sheet and mixed in situ on the sheet. The cosmetics may take the form of any semi-solid or liquid product suitable for application to the skin, lips, hair, eyelashes and/or eyebrows, such as creams, ointments, solutions, creams, hair oils, gels, creams or mascaras. Preferred products are foundations, concealers, body creams, and lipsticks and lip glosses. The compositions of the present invention may optionally contain other active and inactive ingredients which are normally formulated with cosmetic and personal care products including, but not limited to, excipients, fillers, emulsifiers, antioxidants, surfactants, film formers, meals. Mixture, gelling agent, thickener, softener, moisturizer, moisturizer, vitamin, sodium ascorbate/cholesteryl phosphate, minerals, botanical drugs, oxygen ellipse, retinoids, hormone compounds , α_transbasic acid, —diacid, α-keto acid, antimycobacterial agent, antifungal agent, antimicrobial agent, antiviral agent, analgesic, lipid compound, antiallergic agent, H1 Or H2 antihistamines, anti-inflammatory agents, anti-irritants, anti-neoplastic agents, immune system enhancers, immune system inhibitors, anti-acne agents, anesthetics, preservatives, insect repellents, skin cooling compounds, skin protectants, skin Penetration enhancers, scrubs, lubricants, perfumes, colorants, stains, agents, hypopigments, preservatives, stabilizers, pharmaceuticals, light stabilizers, and mixtures thereof. The following examples of the present invention are intended to be carried out in a non-limiting manner. [Embodiment] 160644.doc • 19-201231095 Example 1 The method for preparing a cosmetic trial sheet is to use different colors of different colonizations and shells at the same time. The liquid of the hue is dropped on different areas of the test piece during makeup. The test sheets are heated to dry out all volatiles of the liquid cosmetics t. (4) The cosmetic droplets are sprayed with a thick layer of water-soluble polymer to prevent the cosmetic from being transferred to other surfaces. The test flakes are then heated in an oven to dry the sprayed polymer. Example 2 Self-Test Sheet Use Cosmetic Trial The consumer selects the desired cosmetic sample suitable for use or testing. If the hole is punched, the test piece from which the test piece is torn off and the test piece retained on the piece is retained for later use. The test article is then wetted with water to make the solid on the test sheet sticky. Then, the Xiao Fei can use his finger to wipe the cosmetic from the trial sheet and apply it to the desired area of the face or skin. Add more or less water to the cosmetic level.卩Improve the color intensity or coverage of certain cosmetic parts. All percentages are by weight unless otherwise indicated. The entire disclosures of all of the patent applications and publications cited herein are hereby incorporated by reference in their entirety herein in their entireties in the the the the the the Each of the patent applications is expressly and individually referred to in its entirety for all purposes. It will be apparent to those skilled in the art that many modifications and variations can be made without departing from the spirit and scope of the invention. The specific embodiments described herein are presented by way of example only, and the present invention is intended to be limited only by the scope of the accompanying claims, and the singularity of the singer by the ancient master t 4ι丨tsi α νϋ· The entire scope of the equivalent of the patented scope is called. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 illustrates a personal care product 10 according to the present invention comprising a substrate 20, a topical formulation deposited on the substrate, a substrate covering the substrate, and a topical application. A solid film of the water-soluble polymer of the formulation, and a removable masking film 5 on the layer of the water-soluble polymer 30. 1A is a cross-sectional view of the personal care product of FIG. 1 . 2 illustrates a cosmetic trial 100 in accordance with the present invention comprising a substrate 120 having perforations 170 defining individual trial zones, each trial zone comprising cosmetic formulations 140A-L, each of which may be the same or different, It is deposited on the substrate 120, a solid film covering the water-soluble polymer 130 of the substrate and the cosmetic formulation J40A-L, and a removable mask on the layer of the water-soluble polymer 130. Film 150. [Main component symbol description] 20 Substrate 30 Water-soluble polymer 40 Topical formulation 160644.doc -21 - 201231095 50 Masking film 100 Cosmetic sample piece 120 Substrate 130 Water-soluble polymer 140A Cosmetic formulation 140B Cosmetic formulation 140C Cosmetic Formulation MOD Cosmetic Formulation 140E Cosmetic Formulation 140F Cosmetic Formulation 140G Cosmetic Formulation 140H Cosmetic Formulation 1401 Cosmetic Formulation 140J Cosmetic Formulation 140K Cosmetic Formulation 140L Cosmetic Formulation 150 Masking Film 170 Perforation-22-160644.doc