201143720 六、發明說明： 【發明所屬之技術領域】 本發明係關於-種腫瘤偵測裝置，特別關於一種可 式腫瘤偵測裝置。 w 【先前技術】 現有的腫瘤镇測方法，—是經由自行觸診，但觸診的 精確度並不m到大醫院藉由超音波、mri·..等等 大型設備進行檢查’但此法需要許多技術人員，無法自行 完成，也無法在很短時間内得到檢查的結果。而且大部分 民眾沒有定期到醫院檢測的，故無法制提早發現的 效果。 因此，如何提供一種可攜式腫瘤偵測裝置，能夠方便 讓使用者自行檢測以達到預防或提早發現之效果，實為當 前重要課題之一。 β 【發明内容】 有鑑於上述課題，本發明之目的為提供一種能夠方便 讓使用者自行檢測之可攜式腫瘤偵測裝置。 為達上述目的’依據本發明之一種可攜式腫瘤偵測裝 置用以彳貞測一組織是否具有腫瘤’其包含一可攜式本體、 複數發光元件以及至少一光感測元件。可攜式本體具有一 處理單元。發光元件設置於可攜式本體之一端，並輪流發 出一光線經由組織繞射，其中任兩發光元件係相距χ公分 201143720 之水平距離。光感測元件鄰設於該等發光元件並與其中一 發光元件相距一 y公分之水平距離，其中χ與y滿足 x$0.1*y之關係式’光感測元件與處理單元電性連接，且 接收該等繞射光線並對應產生複數感測訊號，處理單元依 據該等感測訊號而決定組織是否具有腫瘤。201143720 VI. Description of the Invention: [Technical Field] The present invention relates to a tumor detecting device, and more particularly to a tumor detecting device. w [Prior Art] The existing method of tumor biopsy, which is self-diagnosis, but the accuracy of palpation is not detected in large hospitals by large equipment such as ultrasound, mri·.. Many technicians are needed, they can't do it themselves, and they can't get the results of the inspection in a short time. Moreover, most people do not regularly go to the hospital for testing, so it is impossible to make early detection. Therefore, how to provide a portable tumor detecting device that can conveniently detect the user to achieve prevention or early detection is one of the important issues. [Explanation] In view of the above problems, an object of the present invention is to provide a portable tumor detecting device that can be easily detected by a user. To achieve the above object, a portable tumor detecting device according to the present invention is for detecting whether a tissue has a tumor, which comprises a portable body, a plurality of light-emitting elements, and at least one light-sensing element. The portable body has a processing unit. The illuminating element is disposed at one end of the portable body and alternately emits a light that is diffracted through the tissue, wherein any two of the illuminating elements are at a horizontal distance of 437 437 201143720. The light sensing element is disposed adjacent to the light emitting element and is separated from the light emitting element by a horizontal distance of one ym, wherein χ and y satisfy the relationship of x$0.1*y, and the light sensing element is electrically connected to the processing unit, and Receiving the diffracted rays and correspondingly generating a plurality of sensing signals, the processing unit determines whether the tissue has a tumor according to the sensing signals.
承上所述，本發明揭露一種可攜式腫瘤偵測裝置，其 包含一可攜式本體可讓使用者握持，發光元件設置於可攜 式本體之一端並輪流發出一光線（例如近紅外線）經由組 織繞射，再被光感測元件吸收而產生感測訊號，由於病變 级織與正常組織之含氧血基血溶素及去氧血基血溶素之 比例不同’故當光線經過正常級織與病變組織時，兩者對 光線吸收的程度亦不同’使得近紅外線光譜經由組織繞射 而收回之訊號強度有所差異。如此，藉由處理單元之處理 即可判斷組織是否具有腫瘤或癌細胞等病變組織。另外， 本發明藉由χ與y毅妙.之關係式 元件與光感測元件之水平距離實質相同，使=發= 係在相同的基準線接收來自各發光元件所發光^ 而簡化分析，並可降低處理單元f 九線，進 早兀（例如微處理器）之成本。 【實施方式】 佳實施例之一 以相同的參照 以下將參照相關_ ’說日績本發明較 種可攜式腫瘤_裝置’其中㈣的元 符號加以說明。 圖1係本發明較佳實施例之 種可攜式腫瘤偵測裝 置 5 201143720 1的外觀示意圖’圖2係可攜式腫瘤偵測裝置1的後視放 大示意圖。請參照圖1及圖2所示，可攜式腫瘤偵測裝置 1包含一可攜式本體η、複數發光元件12及一光感測元 件13。可攜式腫瘤偵測裝置1係用以讓使用者握持並靠近 身體以進行病變組織（例如腫瘤或癌症）之偵測。本實施 例所指之腫瘤係泛指一般病變組織，例如一般腫瘤或癌症 等。 本發明不限制可攜式本體11之形狀，其可製成為手 機外型或手把外型以利使用者握持。 發光元件12係設置於可攜式本體u之一端。本實施 例之發光元件12係以發光二極體（LED)為例。發光元件 12之數量只要大於2皆可’於此係以6顆LED為例。發 光元件12係輪流發出一光線，於此並無特定之發光順序， 可例如以排序為其發光順序，例如從圖2之上方到下方之 順序。當使用者握持可攜式腫瘤偵測裝置1進行偵測時， 發光元件12所發出之光線係經由人體組織（例如乳房） 繞射（可包含散射）。 各發光元件12係發出不同波長之光線，於此，各發 光元件12所發出之光線波長分別為69〇nm、760nm、 8〇5nm、85〇nm、910nm、97〇nm，其中 69〇nm 係用以膚色 校正，760nm係對應去氧血紅素、8〇5nm係對應去氧血紅 素與含氧血紅素於光谱上之父點並可表徵總血量，85Onm 係對應含氧友紅素、91 Onm係對應水、97〇nm係對應脂肪。 另外，為提升訊號判讀之能力，可攜式腫瘤偵測裝置i可 201143720 更包含一濾光片14,設置於該等發光元件12之光路徑上， 使光線經由濾羌片14再到達光感測元件13。本實施例之 濾光片14可將650nm以下之光線排除以消除可見光之干 擾。 光感測元件13係鄰設於該等發光元件12。光感測元 件13可例如為光電二極體或電荷耦合元件（CCD)等等 可將光線轉換為電訊號之元件。 需注意的是，如圖2所示，任兩發光元件（圖2係以 • 上面算來第2顆及第3顆為例）之中心點係相距X公分之 水平距離，而光感測元件13係與其中一發光元件（不限 制哪一顆，於此係以第4顆為例）相距一 y公分之水平距 離，其中X與y滿足χ^Ο. 1 *y之關係式，藉此可限制各發 光元件12與光感測元件13之水平距離實質相同，使得光 感測元件13係在相同的基準線接收來自各發光元件12所 發出之光線，進而簡化分析。在本實施例中，發光元件12 鲁係排成一行，並位於光感測元件13之一側。需補充說明， X可能是製造誤差所造成、或是刻意迴避設計所造成，而 後者應被視為與本發明之概念相同。另外，X越大則產生 訊號之分析難度越高，但X仍有一合理範圍。 在繼續說明可攜式腫瘤偵測裝置1之操作之前，需先 說明光線繞射（包含散射）的情況。請參照圖3及圖4所 示，其係顯示發光元件12發射光線，光線經由組織内繞 射，並穿出而由光感測元件接收，其中圖3之組織係正常 組織，圖4之組織係具有病變組織T，由圖4可知，繞射 201143720 光線之一部分會由病變組織T吸收，使得光感測元件13 所接收到之光線強度減弱。 圖5係使用者握持可攜式腫瘤偵測裝置1進行偵測的 操作示意圖，其中使用者係沿一水平方向進行掃描偵測。 在偵測時，發光元件12係輪流發射不同波長之光線，並 經由組織繞射而由光感測元件13吸收並對應產生複數感 測訊號。光感測元件13與設置於可攜式本體11内之一處 理單元（圖未顯示）電性連接，處理單元係接收並處理感 測訊號，於此，處理單元可包含一數位/類比轉換電路 (Digital to analog converter, DAC)，可將光感測元件 η 所產生之數位感測訊號轉換成類比感測訊號。另外，處理 單元可依需要而具有例如濾波電路、比較電路等，於此， 處理單元具有低通濾波電路（low pass filter, LPF)以將高 頻雜訊據除。 感測訊號之波形可參照圖6所示’其中X軸單位係毫 秒（ms)，γ轴單位係電壓（voltage) ’且圖6係以病變組 織為例。由圖6可知，當可攜式腫瘤偵測裝置1沿著如圖 5所示之方向掃插，且一開始掃描到正常組織時，訊號係 沒有特別的改變（〇ms至8〇〇ms)，而當掃描到病變組織 時，訊號強度係顯著的下降（ 900ms至1350ms)，此因部 分光線被病變組織吸收，然後當再次掃描到正常組織時， 訊號強度又回到正常值（iSOOms至2500ms)。藉此，處理 單元可依據該等感測訊號而決定組織是否具有腫瘤。 另外，由圖6亦可得知，感測訊號皆具有相同之趨勢， 201143720 例如幾乎同時間下降或上升，這是由於本實施例之發光元 件與光感測元件之水平距離係實質相同所造成的。因此， 本實施例可簡化分析，並可降低處理單元（例如微處理器） 之成本。 此外，由圖6亦可知，所有發光元件12所對應的感 測訊號之波形皆有相似的趨勢，這也證明本實施例僅需要 2個以上之發光元件12即可判斷是否具有腫瘤存在。 當發光元件12與光感測元件13之距離（y)越遠時， * 發光元件12所發出之光線需經過較長的距離才能到達光 感測元件13，而其中可能會增加雜訊干擾及訊號衰減的機 會而影響準確度，並可能使得圖6所示之波形下降的時間 拉長、下降的幅度較小而不利判斷。並且y越大越不利薄 型化。經由驗證，當發光元件12與光感測元件13之距離 (y)小於3公分時，可使準確度得到顯著提升結果。 另外，可攜式腫瘤偵測裝置1亦可具有複數光感測元 鲁件13，如圖7所示，其係顯示兩光感測元件13與發光元 件12設置的態樣。其中，兩光感測元件13鄰設於該等發 光元件12並使該等發光元件12實質位於兩光感測元件13 之中心，且兩光感測元件13分別吸收該等繞射光線而對 應產生感測訊號。需說明的是，圖7所示之發光元件12 係以較誇大的比例繪製，實際上，該等發光元件12係實 質位於二光感測元件13之中心範圍。 當使用者使用具有兩光感測元件13之可攜式腫瘤偵 測裝置1掃描腫瘤組織時，其中一光感測元件13會先接 201143720 收到發光元件12所發出且經過腫瘤之光線，其感測訊號 波形可例如圖8A所示，然後使用者持續掃描時，另一光 感測元件13亦會接收到發光元件12所發出且經過腫瘤之 光線，其感測訊號波形可例如圖8B所示。由圖8A及圖 8B可知，兩者之波形下降的時間點存在一時間差，這是因 為光感測元件13設置於發光元件12兩侧的原因。藉由圖 8A與圖8B的波形可更加準確地判斷腫瘤存在與否及腫瘤 位置。 此外，本實施例之處理單元係可使兩光感測元件13 所產生之該等感測訊號建立一函數關係而對應產生複數 處理訊號，並依據該等處理訊號決定組織是否具有腫瘤。 於此，處理訊號之波形如圖9所示，本實施例之處理訊號 係藉由圖8A與圖8B之感測訊號建立一函數關係而產生。 需先說明，假設圖8A所示之波形係藉由設置於發光元件 之左側（L)的光感測元件13所產生，而圖8B所示之波 形係藉由設置於發光元件之右側（R)的光感測元件13所 產生。這樣，圖9所示之波形係由log(L)-log(R)所形成。 如此，當圖9所示之橢圓虛線區域出現時，即證明腫瘤存 在並得知腫瘤位置。在實施上，當處理單元分析到橢圓虛 線區域時，可攜式腫瘤偵測裝置1可發出嗶嗶聲提醒使用 者，而這時腫瘤之位置即在發光元件12附近。 另外，可攜式腫瘤偵測裝置1亦可具有數量大於2之 光感測元件13，如圖10所示，其係顯示四光感測元件13 與發光元件12設置的態樣。其中，該等光感測元件13鄰 201143720 設於該等發光元件12並使該等發光元件12實質位於四光 感測元件13之中心，且四光感測元件13分別吸收該等繞 射光線而對應產生感測訊號。其中，各光感測元件13所 產生之感測訊號可蒼照圖8A、圖8B及圖9’於此不再贅 述。 以下舉例說明圖10之態樣用於腫瘤偵測所會遇到的 情況。如圖11A所示，腫瘤T係位於發光元件12與光感 測元件13a之間，此時，光感測元件13a之訊號強度係小 ® 於光感測元件13b之訊號強度，而光感測元件13c之訊號 強度係等於光感測元件13d之訊號強度，如此，處理模組 係可判斷決定腫瘤之位置係位於發光元件12與光感測元 件13 a之間。 如圖11B所示，腫瘤T係位於發光元件12與光感測 元件13c之間，此時，光感測元件13c之訊號強度係小於 光感測元件13d之訊號強度，而光感測元件13a之訊號強 φ 度係等於光感測元件13b之訊號強度，如此，處理模組係 可判斷決定腫瘤之位置係位於發光元件12與光感測元件 13c之間。 如圖11C所示，腫瘤T係位於發光元件12與光感測 元件13c與光感測元件13a之間，此時，光感測元件13c 之訊號強度係小於光感測元件13d之訊號強度，而光感測 元件13a之訊號強度係小於光感測元件13b之訊號強度， 如此，處理模組係可判斷決定腫瘤之位置係位於發光元件 12與光感測元件13c與光感測元件13a之間。 η 201143720 藉由上述機制可得到腫瘤之位置以達到腫瘤定位功 能，而在定位的過程中可加入即時導引功能，例如當處理 單元決定該組織具有腫瘤時，可攜式腫瘤偵測裝置1可發 出一提示以指明具有腫瘤或腫瘤之方位。 圖12係可攜式腫瘤偵測裝置1的方塊示意圖，如圖 12所示，可攜式腫瘤偵測裝置1係包含複數發光元件12、 光感測元件13、處理單元15、一提示單元16及一無線傳 輸單元17。其中，發光元件12、光感測元件13及處理單 元15已詳述於上面實施例。提示單元16係與處理單元15 電性連接，當處理單元15決定組織具有腫瘤時，處理單 元15控制提示單元16發出一提示以指明具有腫瘤或腫瘤 之方位以達到即時導引功能，提示單元16可包含喇叭或 發光元件以發出聲音或亮光。無線傳輸單元17係與處理 單元15電性連接，可傳送該等感測訊號或具有腫瘤之判 斷至其他電子裝置，例如醫院的伺服器。 另外，上述6個感測訊號除了可用來比較訊號強度以 判斷腫瘤及其位置之外，感測訊號亦可利用公式來計算出 去氧血紅素、含氧血紅素、水、脂肪之組織成分並與資料 庫之資料進行比對以準確得知腫瘤之存在及其類型。而前 述其中一發光元件12(於此係以690nm為例）.係可作為 膚色校正，其校正方法可有二種，一種係將用於膚色校正 之感測訊號帶入公式以求得校正過之去氧血紅素、含氧血 紅素、水、月旨肪之成分。另一種係利用找查表（look-up table) 方式，其找查表之示意可例如如下： 12 201143720 訊號強度 去氧血紅素 A! διι 八2 §21 a3 各31 A4 §41 • · · • · · 含氧jk紅素As described above, the present invention discloses a portable tumor detecting device comprising a portable body for holding by a user, and the light emitting component is disposed at one end of the portable body and alternately emits a light (for example, near infrared rays). ) through the tissue diffraction, and then absorbed by the light sensing element to produce a sensing signal, because the ratio of the oxidized blood-based blood lysin and the deoxygenated blood-soluble blood lysin of the diseased woven tissue to the normal tissue is different When the normal grade is woven and the diseased tissue, the degree of light absorption is also different. 'The signal intensity of the near-infrared spectrum recovered by tissue diffraction is different. Thus, the treatment of the processing unit can determine whether the tissue has a diseased tissue such as a tumor or a cancer cell. In addition, in the present invention, the horizontal distance between the relational element and the photo-sensing element is substantially the same by y and y, and the simplification of the analysis is performed by receiving the light emitted from each of the light-emitting elements on the same reference line. It can reduce the cost of processing unit f nine lines, early (such as microprocessor). [Embodiment] One of the preferred embodiments will be described with reference to the related Japanese _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ 1 is a schematic diagram of the appearance of a portable tumor detecting device according to a preferred embodiment of the present invention. 5 201143720 1 FIG. 2 is a rear view enlarged view of the portable tumor detecting device 1. Referring to FIG. 1 and FIG. 2, the portable tumor detecting device 1 includes a portable body η, a plurality of light-emitting elements 12, and a light sensing element 13. The portable tumor detecting device 1 is for allowing a user to hold and approach the body for detecting a diseased tissue such as a tumor or cancer. The tumor system referred to in this embodiment generally refers to a general diseased tissue such as a general tumor or cancer. The present invention does not limit the shape of the portable body 11, and can be made into a hand shape or a handle shape for the user to hold. The light emitting element 12 is disposed at one end of the portable body u. The light-emitting element 12 of the present embodiment is exemplified by a light-emitting diode (LED). The number of the light-emitting elements 12 may be greater than two. Here, six LEDs are taken as an example. The illuminating element 12 emits a ray of light in turn, and there is no specific order of illumination, which may, for example, be ordered in the order in which it is illuminated, e.g. from the top to the bottom of Figure 2. When the user holds the portable tumor detecting device 1 for detection, the light emitted by the light-emitting element 12 is diffracted through human tissue (for example, a breast) (which may include scattering). Each of the light-emitting elements 12 emits light of different wavelengths. Here, the light-emitting elements 12 emit light having wavelengths of 69 〇 nm, 760 nm, 8 〇 5 nm, 85 〇 nm, 910 nm, and 97 〇 nm, of which 69 〇 nm is For skin color correction, 760nm corresponds to deoxyhemoglobin, 8〇5nm corresponds to the parent point of deoxyhemoglobin and oxygenated heme in the spectrum and can represent the total blood volume, 85Onm corresponds to oxygenated erythropoietin, 91 The Onm corresponds to water and the 97〇nm system corresponds to fat. In addition, in order to improve the ability of the signal interpretation, the portable tumor detecting device i 201143720 further includes a filter 14 disposed on the light path of the light-emitting elements 12 to allow light to reach the light perception via the filter 14 Measuring element 13. The filter 14 of this embodiment can exclude light below 650 nm to eliminate visible light interference. The light sensing elements 13 are disposed adjacent to the light emitting elements 12. The light sensing element 13 can be, for example, a photodiode or a charge coupled device (CCD) or the like that converts light into an electrical signal. It should be noted that, as shown in Fig. 2, the center points of any two light-emitting elements (Fig. 2 is based on the second and third figures calculated above) are horizontal distances of X cm apart, and the light sensing elements The 13 series is separated from one of the light-emitting elements (which is not limited, and the fourth one is taken as an example), and X and y satisfy the relationship of χ^Ο.1*y, thereby The horizontal distance between each of the light-emitting elements 12 and the light-sensing element 13 can be substantially the same, so that the light-sensing elements 13 receive the light emitted from the respective light-emitting elements 12 at the same reference line, thereby simplifying the analysis. In the present embodiment, the light-emitting elements 12 are arranged in a row and are located on one side of the light sensing element 13. It should be added that X may be caused by manufacturing errors or deliberately avoiding design, and the latter should be considered to be the same as the concept of the present invention. In addition, the larger the X, the higher the difficulty of analyzing the signal, but X still has a reasonable range. Before continuing to explain the operation of the portable tumor detecting device 1, it is necessary to explain the case of light diffraction (including scattering). Referring to FIG. 3 and FIG. 4, it is shown that the light-emitting element 12 emits light, the light is diffracted through the tissue, and is received by the light-sensing element, wherein the tissue of FIG. 3 is a normal tissue, and the organization of FIG. It has a diseased tissue T. As can be seen from Fig. 4, a portion of the light that is diffracted 201143720 is absorbed by the diseased tissue T, so that the intensity of the light received by the light sensing element 13 is weakened. FIG. 5 is a schematic diagram of the operation of the user holding the portable tumor detecting device 1 for detecting, wherein the user performs scanning detection in a horizontal direction. In the detection, the light-emitting elements 12 emit light of different wavelengths in turn, and are absorbed by the light-sensing element 13 through the tissue diffraction and correspondingly generate a plurality of sensing signals. The light sensing component 13 is electrically connected to a processing unit (not shown) disposed in the portable body 11. The processing unit receives and processes the sensing signal. The processing unit may include a digital/analog conversion circuit. (Digital to analog converter, DAC), can convert the digital sensing signal generated by the light sensing element η into an analog sensing signal. In addition, the processing unit may have, for example, a filter circuit, a comparison circuit, and the like as needed. Here, the processing unit has a low pass filter (LPF) to divide the high frequency noise. The waveform of the sensing signal can be referred to as shown in Fig. 6 where the X-axis unit is milliseconds (ms), the γ-axis unit voltage (voltage) and FIG. 6 is exemplified by the lesion tissue. As can be seen from FIG. 6, when the portable tumor detecting device 1 is swept in the direction as shown in FIG. 5, and the scanning to normal tissue is started, there is no special change in the signal system (〇ms to 8〇〇ms). When the lesion is scanned, the signal intensity drops significantly (900ms to 1350ms), because some of the light is absorbed by the diseased tissue, and then when it is scanned again to normal tissue, the signal intensity returns to normal (iSOOms to 2500ms). ). Thereby, the processing unit can determine whether the tissue has a tumor according to the sensing signals. In addition, as can be seen from FIG. 6, the sensing signals all have the same tendency, and 201143720, for example, decreases or rises almost simultaneously, because the horizontal distances of the light-emitting elements and the light-sensing elements of the embodiment are substantially the same. of. Therefore, this embodiment can simplify the analysis and reduce the cost of a processing unit such as a microprocessor. In addition, as can be seen from Fig. 6, the waveforms of the sensing signals corresponding to all of the light-emitting elements 12 have similar trends, which also proves that only two or more light-emitting elements 12 are required in the present embodiment to determine whether or not a tumor exists. When the distance (y) of the light-emitting element 12 from the light-sensing element 13 is farther, the light emitted by the light-emitting element 12 needs to travel a long distance to reach the light-sensing element 13, which may increase noise interference and The opportunity of signal attenuation affects the accuracy, and may cause the time of the waveform drop shown in FIG. 6 to be elongated and the amplitude of the drop is small and unfavorable. And the larger y is, the more disadvantageous it is. By verification, when the distance (y) of the light-emitting element 12 from the light-sensing element 13 is less than 3 cm, the accuracy can be significantly improved. In addition, the portable tumor detecting device 1 can also have a plurality of light sensing element members 13, as shown in FIG. 7, which display the two light sensing elements 13 and the light emitting elements 12 disposed. The two light sensing elements 13 are disposed adjacent to the light emitting elements 12 and the light emitting elements 12 are substantially located at the center of the two light sensing elements 13, and the two light sensing elements 13 respectively absorb the diffracted rays. Generate a sensing signal. It should be noted that the light-emitting elements 12 shown in Fig. 7 are drawn at a relatively large scale. In fact, the light-emitting elements 12 are substantially in the center of the two-light sensing elements 13. When the user scans the tumor tissue using the portable tumor detecting device 1 having the two light sensing elements 13, one of the light sensing elements 13 first receives the light from the light emitting element 12 and passes through the tumor, which is received by 201143720. The sensing signal waveform can be, for example, as shown in FIG. 8A. When the user continues to scan, the other light sensing component 13 also receives the light emitted by the light-emitting component 12 and passes through the tumor. The sensing signal waveform can be, for example, as shown in FIG. 8B. Show. As is apparent from Figs. 8A and 8B, there is a time difference at the time point when the waveforms of the two are lowered, because the photo sensing elements 13 are disposed on both sides of the light-emitting element 12. The presence or absence of tumor and the location of the tumor can be more accurately determined by the waveforms of Figs. 8A and 8B. In addition, the processing unit of the present embodiment can establish a functional relationship between the sensing signals generated by the two light sensing elements 13 to generate a complex processing signal, and determine whether the tissue has a tumor according to the processing signals. Here, the waveform of the processing signal is as shown in FIG. 9. The processing signal of this embodiment is generated by establishing a functional relationship between the sensing signals of FIG. 8A and FIG. 8B. It should be noted that the waveform shown in FIG. 8A is generated by the light sensing element 13 disposed on the left side (L) of the light emitting element, and the waveform shown in FIG. 8B is disposed on the right side of the light emitting element (R). The light sensing element 13 is produced. Thus, the waveform shown in Fig. 9 is formed by log(L)-log(R). Thus, when the elliptical dotted line area shown in Fig. 9 appears, it is confirmed that the tumor exists and the tumor position is known. In practice, when the processing unit analyzes the elliptical virtual line region, the portable tumor detecting device 1 can beep to alert the user, and the position of the tumor is near the light-emitting element 12. In addition, the portable tumor detecting device 1 can also have a number of light sensing elements 13 greater than two, as shown in Fig. 10, which shows the arrangement of the four light sensing elements 13 and the light emitting elements 12. Wherein, the light sensing elements 13 are adjacent to the light-emitting elements 12 and the light-emitting elements 12 are substantially located at the center of the four-light sensing elements 13, and the four-light sensing elements 13 respectively absorb the diffracted rays. Corresponding to the generation of sensing signals. The sensing signals generated by the light sensing elements 13 can be omitted as shown in FIG. 8A, FIG. 8B and FIG. 9'. The following is an example of the situation in Figure 10 for tumor detection. As shown in FIG. 11A, the tumor T is located between the light-emitting element 12 and the light-sensing element 13a. At this time, the signal intensity of the light-sensing element 13a is small, and the signal intensity of the light-sensing element 13b is small, and the light is sensed. The signal intensity of the component 13c is equal to the signal intensity of the light sensing component 13d. Thus, the processing module can determine that the location of the tumor is located between the light emitting component 12 and the light sensing component 13a. As shown in FIG. 11B, the tumor T is located between the light-emitting element 12 and the light-sensing element 13c. At this time, the signal intensity of the light-sensing element 13c is smaller than the signal intensity of the light-sensing element 13d, and the light-sensing element 13a The signal intensity φ is equal to the signal intensity of the light sensing element 13b. Thus, the processing module can determine that the position of the tumor is located between the light emitting element 12 and the light sensing element 13c. As shown in FIG. 11C, the tumor T is located between the light-emitting element 12 and the light-sensing element 13c and the light-sensing element 13a. At this time, the signal intensity of the light-sensing element 13c is smaller than the signal intensity of the light-sensing element 13d. The signal intensity of the light sensing component 13a is smaller than the signal intensity of the light sensing component 13b. Thus, the processing module can determine that the position of the tumor is located in the light emitting component 12 and the light sensing component 13c and the light sensing component 13a. between. η 201143720 The position of the tumor can be obtained by the above mechanism to achieve the tumor positioning function, and the immediate guiding function can be added during the positioning process, for example, when the processing unit determines that the tissue has a tumor, the portable tumor detecting device 1 can A prompt is issued to indicate the location of the tumor or tumor. 12 is a block diagram of a portable tumor detecting device 1. As shown in FIG. 12, the portable tumor detecting device 1 includes a plurality of light emitting elements 12, a light sensing element 13, a processing unit 15, and a prompting unit 16. And a wireless transmission unit 17. Among them, the light-emitting element 12, the light-sensing element 13, and the processing unit 15 have been described in detail in the above embodiments. The prompting unit 16 is electrically connected to the processing unit 15. When the processing unit 15 determines that the tissue has a tumor, the processing unit 15 controls the prompting unit 16 to issue a prompt to indicate the orientation of the tumor or the tumor to achieve the instant guiding function, and the prompting unit 16 A horn or illuminating element can be included to emit sound or light. The wireless transmission unit 17 is electrically connected to the processing unit 15, and can transmit the sensing signals or have a tumor to other electronic devices, such as a server of a hospital. In addition, the above six sensing signals can be used to compare the signal strength to determine the tumor and its position, and the sensing signal can also use the formula to calculate the tissue components of the oxygen hemoglobin, the oxygenated hemoglobin, the water, and the fat. The data in the database were compared to accurately understand the presence and type of the tumor. The above-mentioned one of the light-emitting elements 12 (herein, 690 nm is taken as an example) can be used as the skin color correction, and the correction method can be used in two ways. One is to bring the sensing signal for skin color correction into the formula to obtain the corrected result. The components of deoxyhemoglobin, oxygenated hemoglobin, water, and moon fat. The other uses a look-up table, which can be as follows: 12 201143720 Signal strength deoxyhemoglobin A! διι 8 2 § 21 a3 Each 31 A4 § 41 • · · • · · Oxygenated jk red pigment
其中’若用於膚色校正之 強度）分別為Ai、A” ΑγΑ4,所對廂丨」如平均 氧jk紅素、水、脂肪各有其校正值δ 另外，本實施例為防止外界光線 偵測裝置1可具有一暗電流操作模式 ，|t*3 J 裝置1位於暗電流操作模式時，該等發光元 --- -» 1 …二去供=素、含 另外，本實施例為防止外界光線的干擾， 駐要 1 -oT S_ 治"0¾添*、Άβ ,、 揭式腫瘤 可攜式腫瘤该測 i元件12孫 光，而光感測元件13係感測一環境光線而產 诉不發 測訊號，使處理單元15藉由環境感_號校感 訊號。需注意的是，當使用者❹巧流操作模式= 用者可將可攜式腫瘤制裝置i靠近身體以提高環境感= 訊號之準確度。 " 本實施例之環境感測訊號例如圖8Α及圖83所示之標 號為「dark」之曲線，由於本實施例係在一較暗的空間内 實施，故環境感測訊號之訊號強度接近0。環境感測訊號 之校正方法可藉由公式或找查表，其中，公式可例如藉由 該等感測訊號扣除環境感測訊號，找查表可仿照上述膚色 校正找查表，於此不再贅述。需注意的是，環境感測訊號 不谭反應環境光綠，也同時反應光感測元件自身訊號的千 13 201143720 優。 綜上所述，本發明揭露一種可攜式腫瘤債測装置，其 包含一可攜式本體可讓使用錢持，發先元件設置於可穩 式本體之—端絲流發出—先線（例如近红外線）經由組 織繞射，再被域測元件吸收而產生制訊號，由於病變 』織”正心織之含氧1基血溶素及去氧也基如溶素之 比例不同’故當光線經紅常組織與病變組織時，兩者對 光線吸收的程度亦不同，使得近紅外線光譜經由組織繞射 而收回之訊號強度有所差異。如此，藉由處理單元之處理 即可判斷組織是否具有腫瘤或癌細胞等病變組織。另外’ 本發明藉由X與y滿SdPy之關係、式，而限制各發光 疋件”光感測4之水平距離實質相同，使得光感測元科 係^相同的基準線接收來自各發光元件所發出之光線，违 而簡化分析，並可降低處理單元（例如微處理器）之成本‘ 以上所述僅絲触，而非為限制脫鄭 本發明之精料料，㈣料行 應包含於後附之申請專利範圍中。 ^改认 【圖式簡單說明] 種可攜式腫瘤偵測裝 圖1係為本發明較佳實施例之 置的外觀示意圖； 後視==明較佳實施例之可携式腫㈣測裝置的 圖3及圖4 in為發光元件發射光線，光線經由組織内 14 201143720 繞射’並穿出而由光感測元件接收的示意圖， 圖5係為使用者握持可攜式腫瘤偵測裝置1進行偵測 的操作示意圖； 圖6係為感測訊號的波形示意圖； 圖7係為兩光感測元件與發光元件的設置示意圖； 圖8A及圖8B係分別為圖7之兩光感測元件所感測之 感測訊號的波形示意圖； 圖9係為處理訊號的波形示意圖； * 圖10係為四光感測元件與發光元件的設置示意圖； 圖11A至圖11C係圖10之態樣用於腫瘤偵測的示意 圖；以及 圖12係為可攜式腫瘤偵測裝置的方塊示意圖。 【主要元件符號說明】 1 :可攜式腫瘤偵測裝置 籲11 :可攜式本體 12 :發光元件 13、13a〜13d :光感測元件 14 :濾光片 15 ··處理單元 16 :提示單元 17 :無線傳輸單元 T :腫瘤 15Wherein 'if the intensity used for skin color correction is Ai, A" Α γ Α 4, respectively, the 丨 丨 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 如 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外 另外The device 1 can have a dark current operation mode, and the |t*3 J device 1 is located in the dark current operation mode, and the light-emitting elements are---- Light interference, resident 1 -oT S_ governance "03⁄4 Tim*, Άβ, 揭 肿瘤 tumor portable tumor test i component 12 Sun Guang, and light sensing component 13 senses an ambient light and prosecute The test signal is not sent, so that the processing unit 15 uses the environmental sense signal. It should be noted that when the user is in the flow mode of operation = the user can bring the portable tumor device i close to the body to improve the sense of environment = signal accuracy. " The environmental sensing signal of the present embodiment has a curve labeled "dark" as shown in Fig. 8A and Fig. 83. Since the embodiment is implemented in a dark space, the signal intensity of the environmental sensing signal is close. 0. The calibration method of the environmental sensing signal can be obtained by using a formula or a look-up table, wherein the formula can deduct the environmental sensing signal by using the sensing signals, for example, the look-up table can be modeled after the skin color correction check table, and no longer Narration. It should be noted that the environmental sensing signal does not reflect the ambient light green, but also reflects the signal of the light sensing component itself. In summary, the present invention discloses a portable tumor debt measuring device, which comprises a portable body that can be used for holding money, and the first component is disposed on the end of the stable body - the first line (for example Near-infrared light is transmitted through the tissue and then absorbed by the domain-measuring component to produce a signal. Because of the difference in the ratio of oxygen-containing lysin and deoxygenase such as lysin When the red tissue and the diseased tissue are different, the degree of light absorption is different, so that the signal intensity of the near-infrared spectrum recovered by the tissue diffraction is different. Thus, the processing unit can determine whether the tissue has A diseased tissue such as a tumor or a cancer cell. In addition, the present invention limits the horizontal distance of each light-emitting element by the relationship between X and y full SdPy, and the horizontal distance of the light sensing 4 is substantially the same, so that the light sensing element is the same The reference line receives the light emitted from each of the light-emitting elements, which simplifies the analysis and reduces the cost of the processing unit (such as a microprocessor). The above-mentioned only silk touch, rather than limiting the invention. Concentrate feed, (iv) in the feed line should contain the scope of the appended patent in. ^Recognition [Simplified Schematic Description] A portable tumor detecting device 1 is a schematic view of a preferred embodiment of the present invention; rear view == the preferred embodiment of the portable swollen (four) measuring device FIG. 3 and FIG. 4 are diagrams showing that the light-emitting element emits light, the light is diffracted through the tissue 14 201143720 and is received by the light-sensing element, and FIG. 5 is a user holding the portable tumor detecting device. 1 is a schematic diagram of the operation of detecting; FIG. 6 is a schematic diagram of the waveform of the sensing signal; FIG. 7 is a schematic diagram of the arrangement of the two light sensing elements and the light emitting element; FIG. 8A and FIG. 8B are respectively two light sensing of FIG. FIG. 9 is a schematic diagram of a waveform of a processed signal; FIG. 10 is a schematic diagram of a configuration of a four-light sensing component and a light-emitting component; FIG. 11A to FIG. A schematic diagram of tumor detection; and FIG. 12 is a block diagram of a portable tumor detecting device. [Main component symbol description] 1 : Portable tumor detecting device 11 : Portable body 12 : Light-emitting elements 13 , 13a to 13d : Light sensing element 14 : Filter 15 · · Processing unit 16 : Prompt unit 17: Wireless transmission unit T: Tumor 15