TW201116314A - Medicament delivery device - Google Patents

Medicament delivery device Download PDF

Info

Publication number
TW201116314A
TW201116314A TW98138010A TW98138010A TW201116314A TW 201116314 A TW201116314 A TW 201116314A TW 98138010 A TW98138010 A TW 98138010A TW 98138010 A TW98138010 A TW 98138010A TW 201116314 A TW201116314 A TW 201116314A
Authority
TW
Taiwan
Prior art keywords
needle
drug delivery
syringe
plunger rod
delivery device
Prior art date
Application number
TW98138010A
Other languages
Chinese (zh)
Other versions
TWI415645B (en
Inventor
Oscar Alexandersson
Original Assignee
Shl Group Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shl Group Ab filed Critical Shl Group Ab
Priority to TW98138010A priority Critical patent/TWI415645B/en
Publication of TW201116314A publication Critical patent/TW201116314A/en
Application granted granted Critical
Publication of TWI415645B publication Critical patent/TWI415645B/en

Links

Abstract

The present invention relates to a medicament delivery device comprising a generally elongated tubular housing having opposite proximal (10) and distal (12) parts; a needle shield sleeve (20) slidably and coaxially arranged inside the housing and wherein a proximal part of said sleeve protrudes a distance outside the proximal part of the housing; a syringe carrier mechanism comprising a syringe carrier (36) slidably and coaxially arranged within the needle shield sleeve, a syringe (16) comprising a stopper (92), a medicament and a needle, wherein said syringe is coaxially arranged within said syringe carrier, and a holding member (46) connected to the syringe carrier; a first activator member (56) slidably and coaxially arranged within the housing and connected to said needle shield sleeve; a second activator member (66) slidably and coaxially arranged within the first activator member; a drive mechanism slidably and coaxially arranged within the second activator member and releasibly connected to the holding member and to the second activator member, said drive mechanism being controlled by the first and the second activator members; characterized in that said second activator member (66) is arranged with information means arranged to cooperate with corresponding interacting means arranged on the distal part of the elongated tubular housing.

Description

201116314 四、 指定代表圖: (一) 本案指定代表圖為:第(一 a )圖。 (二) 本代表圖之元件符號簡單說明: 10 近端外殼部 12 末端外殼部 16 針筒 22 近端部 36 針筒載具 76 末端橫狀牆 78 資訊構件 80 開口 82 末端牆 90 柱塞桿 92 瓶塞 94 第一壓縮彈簧 98 近端牆 100 導桿 五、 本案若有化學式時,請揭示最能顯示發明特徵的化學式: 六、發明說明: 【發明所屬之技術領域】 本發明係關於一藥物輸送裝置,特別是關於完 整藥物輸送措施而能提供資訊的裝置。 201116314 【先前技術】 地妗!有ϊ多藥物輸送裝置能夠自動或半自動 求^功^。廷些裝置包括許多互動元件來得到所 藥物此:^的病其串中皮-膚種/二主射器能夠輸送 能;-類似的^^==物= 置於末端的-按紐形式呈現。= s: m2完成時,注射器内的穿刺機制被鬆 成。错此,左射針被推入病患體内。此後注射即完 :注射完成時,病患從注射處抽回注射器, 鎖住。十頭保護套被向前推直到圍繞注射針’然後承 1於以上描述的注射針種類 =注射完成且可安全的移開注射針。 者注射狀態的解決辦法已被開發出來。 沾^ *6,221 ’〇46描述一注射裝置有一,,注射结束 伸ί Γ: Λ括一劑量指示機制的彈性標籤上“ 造成掉入外殼内一溝槽,於注射結束時 一可被聽見的喀嚓聲。us 2004/0097883公開 類似注射結束的喀嚓聲解決辦法。 有4二J用fϊ藥物輸送裝置,即使 樂物輸送裝置的輸送措施。琨工門尤其關於 【發明内容】 缺點本發明最主要目的為補救現今藥物輸送裝置的 201116314 發明ΐ 匕圍Λ立直項的特徵來完成。本 的。 式成為此專利範圍附屬項的標 裝置根!ίΐΓ月ΐ主要觀點’其特徵在於藥物輸送 末端部:殼有相對的近端和 殼内邱,日i +二°蒦套可β動且同軸地被安置於外 内’-針匕 載具内,且j支撐軸地被置於該針筒 動構件可滑動⑶=-啟 ΐ以ί動構ί二啟㈣冓件可滑動且同軸地 被安置於第二啟動:件:驅且同軸地 置,其與瘦該第一啟動構件備有資訊裝 構件附於第二啟動構件之末置包括-資訊 括1口被安㈡狀 ί ί ί :::點,該資訊構件為特有顏色。 作用於該針筒内之瓶:孝驅=:包括-柱塞桿 瓶塞經由注射針:仏%,。並移動該 地被安、於内柱;桿:滑動地且同軸 動構件内,且預先被壓縮的第一 201116314 ,,彈簧同軸地被置於柱塞桿内(柱塞桿之近 和第二啟動構件之末端橫狀牆之間)。 σ 根據本發明另一觀點,第二啟動構件 ::物有環狀向内壁架,在此支撐構=== =環内壁架,且在此柱塞桿包括-圓周溝 =第二啟動構件的壁架和支樓構件的壁架有一共 二』狀,以便第二啟動構件的環狀向内壁架和支撐 構件的放射狀向内壁架可合入溝槽。 支撐 内的一觀點,柱塞桿藉由柱塞桿溝槽 =!:壓縮彈菁之力被支撐著彳藉:;= 動構件裱繞且防止舌狀物放射狀地向外移動。 媳沾ί據ί發明另一觀點,此裝置又包括-預先壓 第二壓縮彈簧有-環狀近端依靠於一第= 構件物,和一環狀末端依靠於第二啟動 構件之停止壁架的近端面。 九别 根據本發明另一觀點, 口;連以r頭保護套=工= 槽被鬆開時,可相===== 之力追使該Σ窠声^成預先壓'缩的第一壓縮彈簧 塞(第二步)Λ。 入針筒承載機制(第一步)和瓶 根據本發明另-觀^ — ήΑ. ^ 末端經過第二啟動槿^ 一啟動構件在柱塞桿 第-壓縮彈簧之殘力後’藉由預先壓縮的 舌狀物放射狀向S動車3末端地移動’以致 端牆撞擊末端外殼部:末:m巧構,的橫末 移ί。 被元成’且裝置可被安全地從注射處 201116314 根據本發明另—_ 末端地移動時,該資2 2山第^二啟動構件同軸且 已被完成,可見資訊來表示注射 根據本發從注射處移除。 構件藉由預先壓缩M g,,二,十頭保濩套和第一啟動 構件之力f二壓縮彈簧作用於第-驅動 端地移# ^ ;外设和第二啟動構件同軸地且近 5 ^w ^ 根掳★欢接於第一啟動構件可覆蓋注射針。 於盆=?:!另一觀點’第-啟動構件包括肋柱 端:移動後盥mm動構件同軸且近 免將針頭保護套向第狀部互動,以避 成注許因為使用者被提供關於完 注射處移開藥物輸以已完成,他/她可安全地從 為壓縮彈簧裝置的殘力被用來穿刺, 庄射^用來提供資訊給使用者。 +牙別 置ηΪϊ!面二資訊可被看見’如:使用者可透過裝 為;匕二口或通道)看収射已實施。再者, 同的lU 可有亮色且/或與其他裝置不 此也:J觸if構件也可被做成穿過裝置外殼,藉 此也徒么觸覺和視覺資訊給使用者。 罢丄ΐ I視覺和/或觸覺資訊之外’根據此發明之裝 音。°有聽覺效果,當注射已實施時發出清楚的聲 X士ΐΐ的安排是將資訊構件置於裝置末端,由於 為了提供資訊功能而使用更多元件,而可助 於设計。 7 201116314 本發明在許多方面可指示注射完成。 本發明的這些和其他優勢,從以下詳細 附圖將顯而易見。 乃和 【實施方式】 曰=前的應用中,末端,意指藥物輪送裝置或 疋構件在注射時離使用者最遠的那端。相同地, :最物輸送装置或是構件在注射時離使用 一击if明的藥物輸送裝置(如:自動注射器)在圖 :中包括一普通瘦長管狀外殼有相對的近端1〇 ,端12。近端外殼部1〇備有瘦長開口 14用來 =筒上6(裝有液態藥物)(圖二)。末端部備有如同& 2凹處的嚙合裝置(如:其内面上)與相應的嚙合 置(如.近端部的近端外面上)互動。 、 裝置又包括一針頭保護套2〇(圖二),自此之 稱為針套,藉此該針套包括一近端部22(有一, 士,)和末端部24(有一直徑大於近端部),此兩二 的圓錐部26連接(圖二)。兩痩長溝槽28沪 ί it兩可用來觀察針筒16(圖二)。在圓錐; 26内面上有一圓周壁架3〇(圖二)。針套末端 口 32在相對面,每一開口都有一稍微向内突出二 性舌狀物34(圖二)。針頭保護套2〇可滑動且间 殼内’且保護套近端部突出外殼近端 、裝置也包括一針筒承載機制包括一針 可滑動且同軸地位於針頭保護套内;針筒16勹: 瓶塞92、藥物和一根# ’藉此該針筒同軸g : =針筒承載機制内;和一支撐構件46連接 201116314 斷流器位於兩邊以形成導面39。這=處有 相應的形狀合作以產生停止播二面,、針套内面 對於針套的旋轉。名十筒載且末右=止#筒载具相 之舌狀物40,每一二個向巧延伸 架於每一開口末端緣上(圖二)。針ί二向内壁 有放射狀向内凸緣以讓針筒载 3 ^面又備 有空間。 艰,u戰具如和針筒16之間 支撐構件46(圖二)包括一環狀 壁架50環繞於其圓周和衣^主體48有一環狀 置末端,且在此;圓舌:物 54(圖一 b)。母舌狀物52備有放射狀向内壁架 裝置也包括一第一啟動構件56可 括且連接於針頭保護套2〇如下所述, 壁架60 -段距離物62/皮文置於外面上離 離慝(圖一)。一第二環狀物64祜容 置於離壁架60更遠之處。 "勿64被女 砧又包&第一啟動構件66可滑動且同軸 写68 ,著一第啟動Λ件56内’為管狀。許多縱向斷流 ^第r動構件近端外面,以便形成彈性舌 二)1彈性舌狀· 70近端有一傾斜轉接面 二 徑的帶狀部72接觸(圖三)。一環狀向内壁 木74位於鄰接轉接面的内面上(圖一 b)。再者,第 f啟動構件66備有資訊裝置,與相應的瘦長管狀外 ^末端上之互動裝置互相合作。該資訊裝置包括一 資訊構件78附於第二啟動構件之末端橫狀牆76, 且該相應的互動裝置包括一開口 8〇位於瘦長管狀 外殼末端部之末端牆82上(圖一 a)。 201116314 第二:=6包6括内:=;=且同轴地位於 *二啟動構件,該驅動機了二地义支 控制,如下所述。 弟一啟動構件 驅動機制包括一柱塞桿9〇作用於 使先:縮的第,彈=ί: 穿刺入么Ϊ(塞第”;動驟===將注射針 地位於第二啟動構件二)預同轴 ί 叫㈣=== 第一啟動構件的末端橫狀牆76 才 桿!〇〇位於第一壓縮彈脊94内(=)再者,一導 柱塞桿90為管狀有一外徑稍小於 塞桿9〇備有一圓周溝槽%,、Κ - = 和支撐構件46的放射狀n向内 96(圖一 b)。 、2永Μ可合入溝槽 止壁架二於第二啟動構件66的停 下。有關圖三〜六’根據本發明裝置之功能將描述如 置固末部端藉由細^ =二啟動構 柱塞藉由柱塞桿9〇溝槽9:内的 啟動構件66之舌狀物70的向内壁架74,和藉 201116314 ΐϊϊί防止舌狀物70以放射狀向外移動mi 啟動構件56’而倚著預先壓縮第動的第- =力被支擇著。再者,支撐構件^的| =簧94 溝槽96内(圖一 b)。針筒載具%的每口位於201116314 IV. Designation of the representative representative: (1) The representative representative of the case is: (i a). (b) The symbol of the representative figure is briefly described: 10 proximal end housing 12 end housing portion 16 syringe 22 proximal end 36 syringe carrier 76 end transverse wall 78 information member 80 opening 82 end wall 90 plunger rod 92 stopper 94 first compression spring 98 proximal wall 100 guide rod 5. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention: 6. Description of the invention: [Technical field of invention] The present invention relates to Drug delivery devices, particularly devices that provide information about complete drug delivery measures. 201116314 [Prior Art] Cellar! There are many drug delivery devices that can be used automatically or semi-automatically. These devices include a number of interactive components to obtain the drug: the disease of the string, the skin-skin type/two-shot device can deliver energy; - a similar ^^== object = at the end - in the form of a button . = s: When m2 is completed, the puncture mechanism in the syringe is loosened. In this case, the left needle is pushed into the patient. After the injection is completed: When the injection is completed, the patient withdraws the syringe from the injection site and locks it. The ten-piece protective sleeve is pushed forward until it surrounds the injection needle' and then the type of injection needle described above = the injection is completed and the injection needle can be safely removed. A solution to the state of injection has been developed. Dip ^6,221 '〇46 describes an injection device that has an injection end extension Γ: A flexible label that includes a dose indicating mechanism "causes a groove that falls into the outer casing and is audible at the end of the injection. Sound. Us 2004/0097883 discloses a click-and-pop solution similar to the end of the injection. There are 4 2 J using the fϊ drug delivery device, even if the delivery device of the music delivery device. The door is especially relevant [invention] The main purpose of the invention In order to remedy the characteristics of the 201116314 invention of the present drug delivery device, it is the standard device attached to this patent scope! The main point of view is that the drug delivery end: shell There is a relative proximal end and a shell inner Qiu, the day i + two ° 蒦 sleeve can be β-moving and coaxially placed in the outer '--needle carrier, and the j support shaft is placed in the needle moving member Sliding (3) = - opening ΐ 动 ( ( 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四Second activation The end of the piece includes - information including 1 port is set by (2) ί ί ί :::, the information component is a special color. The bottle acting on the syringe: filial drive =: including - plunger rod stopper via Injection needle: 仏%, and move the ground to be mounted on the inner column; rod: the first 201116314 that slides and is in the coaxial moving member and is compressed in advance, the spring is coaxially placed in the plunger rod (column Between the vicinity of the plug stem and the end transverse wall of the second actuating member. σ According to another aspect of the invention, the second actuating member: the object has an annular inward ledge, where the support structure === = inner wall of the ring And the plunger rod includes a circumferential groove = a ledge of the second actuating member and a ledge of the branch member having a common shape so that the annular starting frame of the second actuating member and the supporting member are radially The inner ledge can be fitted into the groove. In the view of the support, the plunger rod is supported by the plunger rod groove =!: the force of the compressed elastic is borrowed:; = the moving member wraps around and prevents the tongue Radially moving outwards. According to another aspect of the invention, the device includes - pre-pressing the second compression spring with a ring-close The end depends on a first member, and an annular end depends on the proximal end face of the stop ledge of the second actuating member. Nine in accordance with another aspect of the invention, the mouth; connected with a r head protector = work = slot When it is released, the force of the phase ===== can be chased by the first compression spring plug (second step) 预先 pre-pressed. The needle bearing mechanism (first step) and According to the invention, the end of the bottle is passed through the second actuating element, after the residual force of the plunger rod first compression spring, by the pre-compressed tongue radial to the end of the S motor 3 The ground moves 'so that the end wall hits the end shell part: the end: m is configured, the end of the movement is ί. The unit can be safely moved from the injection site 201116314 according to the invention - _ end of the capital The 2 2nd second activation member is coaxial and has been completed, and information can be seen to indicate that the injection was removed from the injection according to the present invention. The member is pre-compressed by M g, the force of the two, ten head guard sleeves and the first actuating member f. The two compression spring acts on the first drive end to move the ground; the peripheral device and the second actuating member are coaxially and nearly 5 ^w ^ Roots ★ The first activation member can cover the injection needle. In the basin =?:! Another point of view 'The first-starting member includes the rib end: after moving, the 动mm moving member is coaxial and the needle protects the needle guard from the first part to avoid the injection because the user is provided about After the injection is removed, the drug delivery is completed, and he/she can safely be used to puncture from the residual force of the compression spring device, which is used to provide information to the user. + 牙 置 Ϊϊ Ϊϊ! Face 2 information can be seen 'such as: users can install through; Furthermore, the same lU may have a bright color and/or be different from other devices: the J-touch component can also be made through the device housing, thereby giving the user a sense of touch and visual information. Dismissal I. In addition to visual and/or tactile information, the sound according to the invention. °Auditory effect, clear sound when the injection has been implemented. X Shi's arrangement is to place the information component at the end of the device, which can be used because it uses more components to provide information functions. 7 201116314 The invention may indicate that the injection is complete in a number of respects. These and other advantages of the invention will be apparent from the accompanying drawings. [Embodiment] In the application of 曰= before, the end means the end of the drug delivery device or the sputum member farthest from the user at the time of injection. Similarly, the most convenient delivery device or component is separated from the drug delivery device (eg, autoinjector) using a single shot. In the figure: a common elongated tubular housing has a relative proximal end 1 , end 12 . The proximal outer casing portion 1 is provided with an elongated opening 14 for use on the cartridge 6 (with liquid medication) (Fig. 2). The end portion is provided with an engagement means like the & 2 recess (e.g., on its inner face) that interacts with a corresponding engagement (e.g., on the outer side of the proximal end of the proximal end). The device further includes a needle guard 2 (Fig. 2), which is referred to herein as a needle sleeve, whereby the needle sleeve includes a proximal end portion 22 (having a stalk) and a distal end portion 24 (having a diameter greater than the proximal end) The two conical sections 26 are connected (Fig. 2). Two long grooves 28 Shanghai ί it can be used to observe the syringe 16 (Figure 2). On the inner surface of the cone; 26 has a circumferential ledge 3 (Fig. 2). The needle end ports 32 are on opposite sides, each opening having a slightly inwardly projecting bisexual tongue 34 (Fig. 2). The needle guard 2 〇 is slidable and the inside of the casing is 'and the proximal end of the protective sleeve protrudes from the proximal end of the casing, and the device also includes a syringe carrying mechanism including a needle slidably and coaxially located within the needle guard; the syringe 16勹: The stopper 92, the drug and a #' thereby the syringe is coaxial g: = within the syringe carrying mechanism; and a support member 46 is connected to the 201116314. The current interrupter is located on both sides to form the guide surface 39. This = there is a corresponding shape cooperation to produce a stop to broadcast two sides, the inside of the needle sleeve for the rotation of the needle sleeve. The ten-cylinder and the right-end=stop#-cylinder-like tongue 40, each of which extends to the end edge of each opening (Fig. 2). The needle has a radial inward flange to allow the syringe to carry a space. Difficult, the support member 46 (Fig. 2) between the arm and the syringe 16 includes an annular ledge 50 surrounding the circumference thereof and the body 48 having an annular end, and here; the round tongue: object 54 (Figure 1 b). The female tongue 52 is provided with a radially inward ledge device and includes a first actuating member 56 that can be attached to and attached to the needle guard 2, as described below, the ledge 60-segment distance 62/peon is placed on the outside Deviation (Figure 1). A second annulus 64 is placed further away from the ledge 60. "Do not 64 female anvil and package & first actuating member 66 is slidable and coaxially written 68, and a first starting member 56 is tubular. A plurality of longitudinal interruptions ^ the outer end of the r-th moving member to form an elastic tongue. 2) 1 elastic tongue-shaped 70. The proximal end of the 70 has a slanted transition surface with a two-diameter strip portion 72 contact (Fig. 3). An annular inward wall 74 is located on the inner face of the adjoining transition surface (Fig. 1b). Furthermore, the fth activation member 66 is provided with an information device that cooperates with the interactive device on the corresponding elongated tubular outer end. The information device includes an information member 78 attached to the end transverse wall 76 of the second activation member, and the corresponding interactive device includes an opening 8〇 on the end wall 82 of the end portion of the elongated tubular casing (Fig. 1a). 201116314 Second: = 6 packs 6 inclusive: =; = and coaxially located in the * two starter components, the drive is controlled by two places, as described below. The starter member driving mechanism includes a plunger rod 9 〇 acting on the first: the first, the squirting = ί: the puncturing into the Ϊ (the first); the moving step === placing the needle in the second starting member Pre-coaxial ί (4) === The end of the first starting member transverse wall 76 is only in the first compression ridge 94 (=) again, a guiding plunger 90 is tubular and has an outer diameter Slightly smaller than the plug rod 9 has a circumferential groove %, Κ - = and the radial n of the support member 46 inward 96 (Fig. 1b). 2, Μ can be joined into the groove stop wall frame II The stopping of the actuating member 66. The function of the device according to the invention will be described as follows: the rear end of the mounting by means of a fine ^=two actuating plunger by means of a plunger rod 9 The inward ledge 74 of the tongue 70 of the actuating member 66, and by the 201116314 ΐϊϊί, prevents the tongue 70 from radially moving the mi-starting member 56' and is biased against the pre-compressed first-th force Furthermore, the support member ^| = spring 94 is in the groove 96 (Fig. 1b). Each cylinder of the syringe carrier is located at %

^的向:壁架穿過支撐構件46的環狀壁架42 J Ϊ二接針筒载具和支撐構件,同時針ί ^ Ϊ 以連接針套和第-啟動構件。朱0末端面, 保護ί = = ί近:2;=處按壓時,針頭 叙媒杜的第一啟動構件相對於外殼和第二μ 預先壓縮的第二壓縮彈簧102同軸地i 當第-啟動構件向末= 物7〇近端放射狀物70的彈性讓舌狀 曰射狀地向外屈曲,造成壁架74#你知 46 ^ίί 射針筒承載機制(第-步):藉此注 先即被造停止。然而預 使支禮構ί4Λ 普之力(作用於柱塞桿)大到迫 吏支46的壁架54移出柱塞桿的溝槽。 才曰縮之第一壓縮彈菁之力繼續迫使該柱夷 的;瓶塞(第二步),且以= Ϊ射ί ^ ί:到達針筒内部近端為止(圖四)。 66的壁架74、彳柱塞桿末端穿過第二啟動構件 預先壓喉、之塗,舌狀物70放射狀向内移動。因為 件t末端之/狀= “狀爿回76上的内面,且有—殘力,第二 201116314 端移動直到第二啟動構件66末端 杈狀脇76上的外面撞擊末端外殼部12之 = (In面、、主St ::聽見之訊號給使用者,指示輸送 五)·。, 成’且裝置可被安全的移開注射處(圖 ^ π再r者#第二啟動構件66的突出物78突出開σ =吏/觸可見,來提供可觸摸和/或?ΐ資 Si:”已被完成(圖五),且當第二啟動構ί 置可,2突出物78經由通道d看見)Ϊ 從注射處移開。為增進可見度,突出 物了使用π色’不同於其他裝置的顏色。 二壓啟動構件藉由預先壓縮的第 同軸地且近端地移動,因此當 接π笛'β Μ ί °卩從注射處移開時,針頭保護套連 接於第一啟動構件以罩住注射針(圖六)。 第一啟動構件56包括肋柱(未標示)於其内面, 針,,護套和第一啟動構件同軸且近端地移動 防針件66之帶狀部72互動,以 防針頭保禮套向末端移入裝置,避免不慎針刺。 限制Ϊΐί;述ΐίί方式和附圖只被視為本發明無 Kii本發明在本專利權範圍内可以許多 【圖式簡單說明】 ^發明在以下詳細說明中,各參照圖如下: 根據本發明之截面圖,圖lb為圖Μ 圖一係根據圖一之爆炸圖。 12 201116314 圖三〜六係根據本發明不同的功能說明之截面圖。 【主要元件符號說明】 ίο 近端外殼部 12 末端外殼部 16 針筒 20 針頭保護套 36 針筒載具 46 支撐構件 56 第一啟動構件 64 第二環狀物 66 第二啟動構件 70 彈性舌狀物 74 向内壁架 76 末端檢狀踏 78 資訊構件 80 開口 82 末端牆 90 柱塞桿 92 活塞 94 第一壓縮彈簧 96 圓周溝槽 102第二壓縮彈簧 七、申請專利範圍: 1.藥物輸送裝置,包括: 一普通痩長管狀外殼有相對的近端(10)和末端(12) 部; 一針頭保護套(20)可滑動且同軸地被安置於外殼内 13The direction of the wall is passed through the annular ledge 42 J of the support member 46 to connect the syringe carrier and the support member, while the needle ί ^ Ϊ is connected to the needle sleeve and the first-starting member. Zhu 0 end face, protection ί == ί近: 2; = at the time of pressing, the first actuating member of the needle media is parallel to the outer casing and the second μ pre-compressed second compression spring 102 is coaxially i when starting The elasticity of the member 70 to the end of the object 7 〇 让 让 让 让 让 让 让 让 让 让 让 让 让 让 让 舌 舌 # # # # # # # # # # # # # # # # # # # # # # # # # # # It was stopped first. However, it is pre-empted that the force of the lever (acting on the plunger rod) is so large that the ledge 54 of the forcing branch 46 moves out of the groove of the plunger rod. The force of the first compressed squash continues to force the column; the stopper (the second step), and = Ϊ ί ^ ί: reaches the inner end of the syringe (Figure 4). The ledge 74 of the 66, the end of the ram plunger rod is pre-pressed by the second actuating member, and the tongue 70 is moved radially inward. Because the end of the piece t/shape = "the inner surface on the ridge 76, and there is a residual force, the second 201116314 end moves until the outer end of the second urging member 66 on the flank 74 hits the end outer casing portion 12 = ( The In face, the main St :: hear signal to the user, indicating the delivery of the fifth), and the device can be safely removed from the injection site (Fig. π再再者# The protrusion of the second activation member 66 78 highlights σ = 吏 / touch visible to provide touchable and / or Si Si: "has been completed (Figure 5), and when the second activation is enabled, 2 protrusions 78 are seen through channel d)移 Remove from the injection site. In order to enhance the visibility, it is highlighted that the color of π is different from that of other devices. The second pressure actuating member is moved coaxially and proximally by the pre-compression, so when the π flute 'β Μ ί °卩 is removed from the injection, the needle guard is connected to the first actuating member to cover the needle (Figure 6). The first actuating member 56 includes a rib (not labeled) on its inner surface, the needle, the sheath and the first actuating member interact coaxially and proximally to move the strip 72 of the needle guard 66 to prevent needle orientation Move the end into the device to avoid inadvertent acupuncture. The invention is not limited to the scope of the present invention. [In the following detailed description, the invention is described in the following detailed description. Cross-sectional view, Figure lb is a diagram Μ Figure 1 is an explosion diagram according to Figure 1. 12 201116314 Figures 3 to 6 are cross-sectional views of different functional descriptions in accordance with the present invention. [Main component symbol description] ίο proximal end housing portion 12 end outer casing portion 16 syringe 20 needle guard 36 syringe carrier 46 support member 56 first activation member 64 second ring 66 second activation member 70 elastic tongue The object 74 is inspected toward the end of the inner ledge 76. Information member 80 Opening 82 End wall 90 Plunger rod 92 Piston 94 First compression spring 96 circumferential groove 102 Second compression spring 7. Patent scope: 1. Drug delivery device, The utility model comprises: a common long tubular outer casing having opposite proximal ends (10) and end portions (12); a needle protective sleeve (20) slidably and coaxially disposed in the outer casing 13

Claims (1)

201116314 圖三〜六係根據本發明不同的功能說明之截面圖。 【主要元件符號說明】 ίο 近端外殼部 12 末端外殼部 16 針筒 20 針頭保護套 36 針筒載具 46 支撐構件 56 第一啟動構件 64 第二環狀物 66 第二啟動構件 70 彈性舌狀物 74 向内壁架 76 末端檢狀踏 78 資訊構件 80 開口 82 末端牆 90 柱塞桿 92 活塞 94 第一壓縮彈簧 96 圓周溝槽 102第二壓縮彈簧 七、申請專利範圍: 1.藥物輸送裝置,包括: 一普通痩長管狀外殼有相對的近端(10)和末端(12) 部; 一針頭保護套(20)可滑動且同軸地被安置於外殼内 13 201116314 保護套近端伸出外殼近端部外一距離; 地被i置;針筒載具(36)可滑動且同軸 rq〇x 一碩保濩套内,一針筒(16)包括一瓶塞 嗲斜二i ^物和一根針’在此該針筒同抽地被置於 Htl’^—支撐構件⑼連接於針筒載具,· 内,且連接於㈣㈣Μ外殼 構件(66)可滑動且同軸地被安 置於第一 :驅同轴地被安置於第二啟動構件 且了 &、開地連接於支撐構件和第二啟動摇杜 二3:巧由和第二啟動構件被控制;, 痩ϊίί;ΐ:ί:?Π66)備有資訊裝置,其與 卜成末柒上之相應互動裝置合作。 在此第1項之藥物輸送裝置, 構件之以二資 =痩長管狀外殼之末端部末端軸)上七: 很錄τ請專利範圍第2頂夕越& ± 在此資訊構件(78)為特有顏色。、之樂物輸送装置 4.根據申請專利範圍第i至3 置,在此驅動機制包括一柱塞桿c勿輸送裝 (16)内之瓶塞(μ)上,和一預务 )作用於該針筒 (94)有一力能夠迫使該柱塞桿(9〇 壓縮彈簧 機制以將注射針穿刺入注射處(第一垓針筒载具 該瓶塞(92)以將藥物經由注射針推;^驟),並移動 (第二步驟)。 14 201116314 5·根據申請專利範圍第4項之藥物輸送農置, 在此柱塞桿可滑動地且同軸地被安置於第二^盖 件内,且預先被壓縮的第一壓縮彈簧(94 桿内(柱塞桿之近端牆㈣和第二啟 之末鳊検狀牆(76)之間)。 千 6.根據申請專利範圍第5項之藥物輸送裝置, 在此第二啟動構件(66)包括彈性舌狀物、 壁’在力此支撐構件(46)包括彈性舌狀物 (52)有%狀向内壁架(54),且在此柱塞桿包括一 溝槽(96)與第二啟動構件(66)的壁架(74) : (,的壁架(54)有-共同形狀,以便第二)啟㈡= %狀向内壁架(74)和支撐構件的放射狀向内 、 可合入溝槽(96)。 永1 ) 7 ·根據申請專利範圍第6項之藥物輸送裝置, m塞桿藉由柱塞桿(9〇)溝槽(96)内的第二、啟動 ί t笛「舌狀物(7〇)的向内壁架(74),倚著預先壓 第一壓縮彈簧之力被支撐著,也藉由第一啟動 構件(56)環繞且防止舌狀物(7〇)放射狀地向外移動。 8.根據申請專利範圍第7項之藥物輸送裝置, ί此ί置又包括一預先壓縮的第二壓縮彈簧(102) 環狀近端依靠於一第一啟動構件(56)之第二環 狀物(64) ’和一環狀末端依靠於第-之停止”(1G4)的近端t。 動構件_ 9·根據申請專利範圍第8項之藥物輸送裝置, 在此針頭保護套和第一啟動構件相連接,當該針頭 15 201116314 保護套近端被對著注射處按壓讓第二啟動構件(66) 之舌狀物(70)的向内壁架(74)從柱塞桿(90)凹槽(96) 被鬆開時,可相對於外殼和第二啟動構件同軸地且 末端地移動’以致形成預先壓縮的第一壓縮彈簧之 力迫使該柱塞桿(90)移入針筒承載機制(第一步)和 瓶塞(第二步)。 1 〇.根據申請專利範圍第9項之藥物輸送裝 置,在此第二啟動構件在柱塞桿末端經過第二啟動 構件(66)的壁架(74)後,藉由預先壓縮的第一壓縮彈 簧(94)之殘力,同軸地且末端地移動,以致舌狀物(7〇) ^射狀向内移動,藉此第二啟動構件(66)的橫末 ^(76)撞擊末端外殼部(12)之末端牆(82),而發出可 孔號表示注射已被完成,且裝置可被安全地 從注射處移除。 u 置二2申請專利範圍第1〇項之藥物輸送裝 資1構件啟動構件同軸且末端地移動時,該 ί H ()穿出該開口(8〇)使可觸摸和/或可看 1置了破女全地從注射處移除。 置二第11項兮藥物輸送裝 簧-驅動構件之力: 動構件可覆射處時’針套連接於第-啟 13.根據申請專利範圍第12項之藥物輸送裝 16 201116314 置,在此第一啟動構件(56)包括肋柱於其内面,在 針頭保護套與第一啟動構件同軸且近端地移動後, 與第二啟動構件(66)之帶狀部(72)互動,以避免將針 頭保護套向末端按壓入裝置。 17201116314 Figures 3-6 are cross-sectional views of different functional descriptions in accordance with the present invention. [Main component symbol description] ίο proximal end housing portion 12 end outer casing portion 16 syringe 20 needle guard 36 syringe carrier 46 support member 56 first activation member 64 second ring 66 second activation member 70 elastic tongue The object 74 is inspected toward the end of the inner ledge 76. Information member 80 Opening 82 End wall 90 Plunger rod 92 Piston 94 First compression spring 96 circumferential groove 102 Second compression spring 7. Patent scope: 1. Drug delivery device, The utility model comprises: a common long tubular outer casing having opposite proximal ends (10) and end portions (12); a needle protective sleeve (20) slidably and coaxially disposed in the outer casing 13 201116314 protective sleeve proximal end protruding from the outer casing a distance outside the end; the ground cover is placed; the syringe carrier (36) is slidable and coaxially rq〇x, and a syringe (16) includes a bottle of slanting dip and a The needle 'where the syringe is placed in the same way as the Htl' ^ - the support member (9) is connected to the syringe carrier, and is connected to the (4) (four) Μ housing member (66) slidably and coaxially disposed first : The drive is placed coaxially in the second The moving member is connected to the supporting member and the second starting rocker 2: the smart and the second starting member are controlled; 痩ϊ ίί; ΐ: ί: Π 66) is provided with an information device, and Cooperation with the corresponding interactive devices on the end of the game. In the drug delivery device of the first item, the member is on the end shaft of the end of the tubular housing of the second member of the tubular body. Seven: The number of the patents is 2, the second eve of the patent is & ± In this information component (78) It is a unique color. , the music conveying device 4. According to the scope of the patent application range i to 3, the driving mechanism includes a plunger rod c not on the bottle stopper (μ) in the delivery device (16), and a pre-action) The syringe (94) has a force that forces the plunger rod (9〇 compression spring mechanism to puncture the needle into the injection site (the first cartridge carrier carries the stopper (92) to push the drug through the needle; ^ )), and move (second step). 14 201116314 5 · According to the patent application scope 4 of the drug delivery farm, where the plunger rod is slidably and coaxially placed in the second cover member, And a first compression spring that is pre-compressed (between the inner rod (four) of the plunger rod (the fourth end of the plunger rod) and the second end of the second wall (76)). According to the fifth paragraph of the patent application scope a drug delivery device, wherein the second activation member (66) comprises an elastic tongue, the wall 'in the force the support member (46) comprises a resilient tongue (52) having a % inwardly ledge (54), and here The plunger rod includes a groove (96) and a ledge (74) of the second activation member (66): (the ledge (54) has a common shape, Then the second) (2) = %-shaped to the inner ledge (74) and the support member radially inward, can be fitted into the groove (96). Yong 1) 7 · According to the drug delivery device of claim 6 The m plug rod is biased against the first compression spring by the second inward of the plunger rod (9〇) groove (96), which activates the tweezing tongue (7〇) of the inward ledge (74). The force is supported, and is also surrounded by the first actuating member (56) and prevents the tongue (7〇) from moving radially outward. 8. The drug delivery device according to claim 7 of the patent application, ί this The device further includes a pre-compressed second compression spring (102). The annular proximal end relies on a second annulus (64) ' of a first activation member (56) and an annular end relies on a first stop. The proximal end of (1G4) t. The moving member _ 9 · The drug delivery device according to claim 8 of the patent application, wherein the needle guard is connected to the first activation member, when the proximal end of the needle 15 201116314 is facing Pressing the injection site causes the inward ledge (74) of the tongue (70) of the second activation member (66) to be loose from the plunger (90) groove (96) When open, it can be moved coaxially and endally relative to the outer casing and the second actuating member to cause the force of the pre-compressed first compression spring to force the plunger rod (90) into the syringe carrying mechanism (first step) and the bottle Plug (second step). The drug delivery device according to claim 9, wherein the second activation member is borrowed from the ledge (74) of the second activation member (66) at the end of the plunger rod. By the residual force of the pre-compressed first compression spring (94), it moves coaxially and endwise, so that the tongue (7〇) is moved inwardly, whereby the second starting member (66) is horizontally ^ (76) impacting the end wall (82) of the end outer casing portion (12), and issuing a smear number indicates that the injection has been completed and the device can be safely removed from the injection. u Set the second 2 patent application scope of the drug delivery package 1 component activation member coaxial and end of the movement, the ί H () through the opening (8 〇) makes touchable and / or can be seen The broken woman was removed from the injection site. Item 2: Item 11: Drug delivery spring-drive member force: When the movable member can be covered, the needle sleeve is connected to the first-initial 13. According to the patent application scope 12 drug delivery device 16 201116314, here The first actuating member (56) includes a rib on its inner face that interacts with the strip (72) of the second actuating member (66) after the needle guard is moved coaxially and proximally with the first actuating member to avoid Press the needle guard into the device at the end. 17
TW98138010A 2009-11-10 2009-11-10 Medicament delivery device TWI415645B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW98138010A TWI415645B (en) 2009-11-10 2009-11-10 Medicament delivery device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW98138010A TWI415645B (en) 2009-11-10 2009-11-10 Medicament delivery device

Publications (2)

Publication Number Publication Date
TW201116314A true TW201116314A (en) 2011-05-16
TWI415645B TWI415645B (en) 2013-11-21

Family

ID=44934768

Family Applications (1)

Application Number Title Priority Date Filing Date
TW98138010A TWI415645B (en) 2009-11-10 2009-11-10 Medicament delivery device

Country Status (1)

Country Link
TW (1) TWI415645B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI644693B (en) * 2013-03-11 2018-12-21 德商賽諾菲阿凡提斯德意志有限公司 Assembly for a drug delivery device
US10751481B2 (en) 2015-07-23 2020-08-25 Shl Medical Ag Variable single dose injector
US10857300B2 (en) 2015-08-19 2020-12-08 Shl Medical Ag Variable single dose medicament delivery device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4448448B2 (en) * 2002-09-24 2010-04-07 エス・ホー・エル・グループ・アクチボラゲット Injection device
EP1572268A1 (en) * 2002-11-25 2005-09-14 Tecpharma Licensing AG Device for automatically injecting an active agent

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI644693B (en) * 2013-03-11 2018-12-21 德商賽諾菲阿凡提斯德意志有限公司 Assembly for a drug delivery device
US10751481B2 (en) 2015-07-23 2020-08-25 Shl Medical Ag Variable single dose injector
US10857300B2 (en) 2015-08-19 2020-12-08 Shl Medical Ag Variable single dose medicament delivery device
US11872378B2 (en) 2015-08-19 2024-01-16 Shl Medical Ag Single dose medicament delivery device

Also Published As

Publication number Publication date
TWI415645B (en) 2013-11-21

Similar Documents

Publication Publication Date Title
TW201102120A (en) Injection device
JP5531144B2 (en) Drug delivery device with feedback signal transmission means
EP2362794B1 (en) Automatic injection device with audible indicator of completed injection
EP2362792B1 (en) Autoinjector with audible indication of completed delivery
TW500616B (en) Automatically operable safety shield system
EP2630981B1 (en) Medicament delivery device
US20070161960A1 (en) Lancet device
JP2013508032A5 (en)
CN108367120A (en) Medicament delivery device
CN113368344B (en) Axial driving mechanism, automatic injection device and using method thereof
CN104906649A (en) Liquid administration device
CN110325234A (en) The security component of medical delivery device
US20210275755A1 (en) Activation assembly for a medicament delivery device
TW201718039A (en) Medicament delivery device
CN102939122B (en) Medicament delivery device
CN111450356A (en) Automatic injection device
TW201116314A (en) Medicament delivery device
CN113209421B (en) Automatic injection device
CN107158524A (en) Safety needle
US20180353710A1 (en) Protective sleeve for syringe
CN212395534U (en) Automatic injection device
TWI569844B (en) Medicament delivery device
CN210865313U (en) Injection training device with sound prompt function
CN107308524B (en) A kind of fast automatic injection device
CN208552731U (en) A kind of disposable syringe with safty pin head cap