201032738 六、發明說明： 【發明所屬之技術領域】 之主流煙中的苯 本發明係有關一種減低吸煙時所產生 并[a]芘之量的香菸。 【先前技術】 吸煙時所產生 除或減低的物質。 之主流煙中的苯并[a]芘係期 望予以去201032738 VI. Description of the Invention: [Technical Field of the Invention] Benzene in mainstream smoke The present invention relates to a cigarette which reduces the amount of [a] sputum produced during smoking. [Prior Art] A substance that is produced or removed during smoking. The benzo[a] lanthanide in mainstream smoke is expected to go
=二，對於使香於之主流煙中的 之技術已有多項記载，其中亦以經 劑而減低之技術為簡便 旱4中加入添灰 WO20G4/11咖μ 。糾麵際公開 W〇2_/110185、美國專利第4248251號以及美國專 中揭示:ί於草絲中添加作為主要添加物質之 $鹽，使香菸之主流煙中的苯并祐等 烴類⑽s或PaHs)之量減1 然而’由於纪與銘、金同為高價之貴金屬，因而在成 权觀點上為不利。而且，已她為埋藏量少之貴金屬之 此外，由於其具有高的觸媒功能，故在汽車、半導體 產業等中夕有需求，因此在調度方面亦為不利。 另外，羧酸金屬鹽以往係意圖用於減低香菸之主流煙 中的一氧化碳之量。例如在美國專利第44897391號中揭示 為了減低氧化碳之產生量而含有6. 5至20%之量的叛酸 驗金屬鹽的菸草組成物。並在日本國特開2006-187260號 公報中記載：為了減低香菸之主流煙中的一氧化碳之量， 而將有機驗金屬鹽以及無機鹼金屬鹽以特定之量調配在菸 3 321723 201032738 草絲中。 然而，在先前技術中並未出現使用羧酸鹼金屬鹽以減 低香菸之主流煙中的苯并[a]芘量之技術。 【發明内容】 [發明所要解決的課題] 本發明之目的係提供一種減低吸煙時所產生之主流煙 中的笨并[a]芘之量的香於。 [用以解決問題之手段] 本發明者等對於用以減低香菸之主流煙中的苯并[a] 芘之量的有效物質專心致志進行檢討之結果，發現乳酸、 酒石酸、琥珀酸、3-羥基丁酸、乙酸以及曱酸之各種金屬 鹽可選擇性地減低香菸之主流煙中的苯并[a]芘之量。 如依本發明即可提供一種具備含有菸草充填材之菸草 條（tobacco rod)的香於，其中，該於草充填材含有去梗於 葉絲，且含有去梗於葉絲重量之0.5至6.0重量％之量的選 自由乳酸金屬鹽、酒石酸金屬鹽、琥珀酸金屬鹽、3-羥基 丁酸金屬鹽、乙酸金屬鹽以及甲酸金屬鹽所成組群之羧酸 金屬鹽Λ \ [發明之效果] 本發明中所使用之羧酸金屬鹽可選擇性地減低香菸之 主流煙中的苯并[a]芘之量。並且，本發明中所使用之羧酸 金屬鹽大致上比鈀低廉，因而可提供較為低價之產生已減 低苯并[a]祐之主流煙的香菸。 【實施方式】 4 321723 201032738 以下’將本發日錢詳加㈣。 充填材含有去錄2含祕草充紐之料I。該於草 的笨并他之量的彻金且^有^減低香終之主流煙令 菸草充填材含有去插狄一， 一般而言，香菸中使用之 以狄…： 茱絲(菸草葉肉絲)、菸草中肋絲、 再生於卓絲或該等之 於早甲职、斤 mt 〇 tb I D物。去梗菸葉絲可經膨化或不經 參 =重t發相對於苯并㈤_量較多的去梗終 Ϊ於卓充填材含有特定比例之缓酸金屬鹽。同時， 係使經乾燥而收縮之终草葉肉絲之組 織藉由一軋化反4膨化劑而膨脹的菸葉絲。 本發明中所使狀賴金屬鹽係由乳酸金屬鹽、酒石 :金屬鹽、琥崎金屬鹽、3,基丁酸金屬鹽、乙酸金屬 :以及甲酸金屬鹽所成組群中選擇，酸金屬鹽以鹼金屬 I為佳’以鉀鹽或鈉鹽為特佳。 本發明中所❹之賴金屬鹽係时祕葉絲重量的 ❹0.5至6.0重量％之量含在於草充填材中。紐金屬鹽之量 未達0.5重量％時，則有無法明顯減低苯并[a]祐之傾向。 羧酸金屬鹽以未超出6. 0蠢麵^果。然 而’綾酸金屬鹽即使以超出去梗菸葉絲重量之6 〇重量％ 之量而添加時，相較於添加6.0重量％時，苯并[a]芘之減 低效果亦未明顯上昇，反而有使香菸芳香味降低之傾向而 不佳。羧酸金屬鹽係以去梗菸葉絲重量的2至6. 〇重量％ 之量而添加者為更IT。""… 如上所述，本發明中所使用之菸草充填材含有膨化及/ 321723 5 201032738 ⑽草葉肉絲)，另外亦可含有终草 丹生於卓絲或該等之 =:々者、含•之 、、、糸及/次再生於草絲之混合物或 m Ο 非膨化之去梗終葉絲與膨化之去梗= 斤成者、或者是含有 /或再生終草絲之混合物或可由其所::與:ί::絲及 如中肋絲、再生終草絲或該等之絲以外之料材（例 般可伯终草充填材之重量的上物）時’去祕葉絲一 中包含黃色種、伯萊（burley)種等。。所使用之於草品種 中肋料去祕葉絲料絲草材（例如終草 中肋、，、糸及/或再生菸草絲）之混合 早 〇 絲中添加緩酸金屬鹽並將其盘复他” τ纟去梗終葉 於草充壤材為由黃色種及/或伯萊：草^合。例如’當 絲、膨化之去梗終葉絲以及終草中=非膨化之去梗終葉 時，預先將上述缓酸金屬鹽以非膨、''糸所構成的混合於草 之去梗終葉絲的總重量的0.5至=之曰去梗終葉絲與膨化 為佳）之量添加在非膨化之去梗养葉2至6重量％ 絲的混合物中，並宜在所得混二、膨化之去梗終葉 或再生終草絲。藉此而更提升苯調配於草中肋絲及/ 丌本开[a]芘之減低效果。此情 321723 6 201032738 中肋絲之中預先添加竣酸金屬鹽。更且， 氣=(贿葉絲、料細粉、黏合劑㈤♦)、 生成物質等在溶媒中混合而做成衆液，並 == 墨延所形成之於草片(一-⑷ 之此、、糸條亦可作秘草域材❹。_，將㈣金屬趟 以所使用之去梗菸葉絲之重量的0. 5 i 6. 0重量%(以2至 6重量％為佳）之量添加在於草片之細絲中。 可在於草充填材中添加香料，例如：可添加薄荷醇 (menthol) ° 可使賴金屬鹽經由任一種適當的方法含在於草充填 材中。例如：可賴酸金屬鹽之水溶液噴霧在去祕葉絲。 含有經添加㈣金屬鹽之去梗料絲岐草充填材在調渴 後’可供以祕之製作。本發明之香終，除了於草充填材 係使用上述含有羧酸金屬鹽之菸草充填材以外，可依一般 的香菸製造方法製作。 參 本發明之含有羧酸金屬鹽的菸草充填材係由香菸捲紙 捲裝成才干（rod)狀（一般為圓柱狀）。香終捲紙可使用一般香 於所使用之以亞麻衆等漿料為基材的任一種香於捲紙。香 於捲紙此以2g/m以上之比例含有如碳酸j弓、碳酸卸等碳酸 鹽，氫氧化#5、氫氧化鎖等氫氧化物之一般所使用的填充 劑。填充劑可以2至8g/m2之比例含在香菸捲紙中。並且， 香终捲紙一般具有22g/m2以上之基重（basis weight)。該 基重通常在80g/m2以下。捲紙之固有通氣度一般為1〇至 60 CU(Coresta Unit) 〇 7 321723 201032738 此外，香菸捲紙中亦可添加檸檬酸或其鹽（鈉鹽、鉀鹽） 等燃燒調節劑。通常，當使用燃燒調節劑時，係在香菸捲 紙中以2重量％以下之比例使用。 本發明係具有與一般香菸相同的構造及外觀。 第1圖係大略呈示本發明之一種型態的香菸之放大透 視圖。同時，第1圖中，香菸並非以一定比例擴大。 第1圖所示之香菸10係具備：包含含有本發明之含羧 酸金屬鹽的菸草充填材之菸草條（第1圖中為圓柱狀桿） 121、與捲裝該终草條之香菸捲紙122的香於條（cigaratte rod)12。香於條12 —般具有17顏至26匪之圓周長、以及 49mm至90mm之長度。在香於條12之基端（亦即，吸煙方 向之下游端）12a可經由裝接紙（tipping paper)14裝設一 般的煙草濾嘴16。在裝接紙14為了取入外部空氣而稀釋 香菸的主流煙，可在香菸之周圍穿設通氣孔（無圖示）。 本發明之香菸可選擇性地減低主流煙中的笨并[a]芘。 [實施例] 以下，依實施例而更詳細地說明本發明。 實施例1至5 此等實施例中，羧酸金屬鹽係使用表1所示之羧酸鹼 金屬鹽，菸草充填材係使用去梗黃色種菸葉絲。 使表1所示之羧酸鹼金屬鹽2. 5g溶解於20ml之超純 水中，將該溶液喷霧在去梗之黃色種菸葉絲50g。如此， 羧酸鹼金屬鹽係以去梗菸葉絲重量之5%的量添加在去梗菸 葉絲中。將添加有羧酸鹼金屬鹽之去梗菸葉絲在22°C之室 8 321723 201032738 溫、60%之相對濕度的調和室中進行48小時以上之調濕。 使用調濕後之去梗菸葉絲與一般的香菸捲紙，以手作業而 製得香菸條。每支香菸條所使用之添加有羧酸鹼金屬鹽的 於草絲之量為735mg，香於條之長度為57mm，香於條之圓 周長為25mm。將具有纖維素乙酸醋絲束（tow)之於草遽嘴 (長度為27mm)作為濾材，並將其經由穿設有通氣孔之裝接 紙裝設在該等香菸條之各自之一端而得到香菸。 比較例1 除了不添加羧酸鹼金屬鹽之外，使用與實施例1至5 中所使用者為相同的去梗黃色種菸葉絲700mg，其餘同樣 操作而製得香菸。 實施例6至10 該等實施例中，羧酸金屬鹽係使用表2所示之羧酸驗 金屬鹽。 使表2所示之羧酸鹼金屬鹽2. 5g溶解於20ml之超純 ⑩水中，將該溶液喷霧在去梗黃色種菸葉絲50g。如此，羧 酸鹼金屬鹽係以去梗菸葉絲重量之5%的量添加在菸草絲 中。將添加有羧酸鹼金屬鹽之菸草絲進行與虞施兩丨1至5 相同之調濕。除了使用該調濕後之絲以外，進行與實施例 1至5相同操作而製得香菸。 比較例2 除了不添加羧酸鹼金屬鹽之外，使用與實施例6至10 中所使用者為相同的去梗黃色種於葉嫌70伽r，其餘同樣 操作而製得香於。 9 321723 201032738 〈香菸之抽吸次數的測定、以及香菸主流煙中之焦油、尼古 丁以及苯并[a]芘之分析〉 A. 香菸主流煙中之粒狀物質的捕集以及抽吸次數的測定： 由實施例1至10以及比較例1至2所製作之香菸的濾 嘴去除纖維素乙酸酯絲束，並以膠帶塞住裝接紙之通氣 孔，將此供予以下操作。 使用備有設置劍橋過濾器（預先測得該重量）之粒狀物 質捕集器的掛有10支線型抽菸器（Cerulean公司製造之 SM410)進行抽菸，在劍橋過濾器中捕集到粒狀物質。香菸 係每次抽吸之抽吸時間為2秒、抽吸容量為35mL、且抽吸 間隔為60秒。使香菸僅燃燒香菸前端至49mm之長度，測 定香菸之抽吸次數並求算出該等之平均值。將結果示於表 1及表2。 B. 焦油以及尼古丁之分析 將捕集有上述粒狀物質之劍橋過濾器的重量進行測 定，由該重量扣掉預先所測定之劍橋過濾器的重量，求算 出粒狀物質之總重量。 在捕集有粒狀物質之劍橋過濾器中添加10mL之異丙 醇（含有喹啉、乙醇作為分析用内部標準）以萃取粒狀物 質。對於該萃取液，係使用GC-FID/TCD(Agilent公司製造 之6890N)，以内部標準法定量水以及尼古丁之量。由粒狀 物質之總重量扣掉所得之水以及尼古丁之重量而求算出焦 油量。 C. 苯并[a]祐之分析 10 321723 201032738 苯并[a]拓在實施例1至10以及比較例1至2中係經 由以下所記載之氣相層析儀之質量分析（GC_MS)法進行分 析，在以下所記載之實施例U至16以及比較例3至4中 係使用以下所記載之尚效液相層析（JJPLC)法進行分析。 C-l : GC-MS 法 與上述之焦油以及尼古丁的分析所進行者同樣進行操 作，得到粒狀物質之異丙醇萃取液.在該萃取液6mL中添 ❹加内部標準溶液（苯并[a]芘重氫取代物之甲醇溶液）以及 14mL之超純水，調製成試驗溶液。將該試驗溶液裝填在cjj 管柱（Varian公司製造之MEGABE-CH，1GM6ML)中。將管柱 乾燥後，以5mL之環己烷洗提。將該洗提液裝填在si管柱 (Sep-Pak Vac 3cc(500mg)Silica Cartridge， Waters 公 司製造）中，並以二氯甲烷/環己烷（1/4)之混合溶媒5mL洗 提。將洗提液濃縮，使用GC-MS(Agilent公司製造之6890N) 以内部標準法進行定量。 ⑩ C-2 : HPLC 法 在捕集有上述粒狀物質之劍橋過濾器中添加環己烷， 使粒狀物質之濃度成為約’震盪30分鐘後進行萃 取。將該萃取液以0. 45 /z m之遽膜過滤後’使用連接有固 相萃取管（soild-phase extraction cartridgeXWater 公 司製造之86口-?>3^關2卩1113)之玫璃注射器採集81111<之滤 液，通過萃取管而回收。所使用之萃取管以7mL之己烧清 洗，旅將該清洗液與上述回收之濾液合併。‘該合佛·之液體 經乾涸後，再使之溶解於lmL的乙腈’使用 11 321723 201032738 (series 1000, HEWLETT PACKARD公司製造）並以絕對校準 法（absolute calibration method)供予苯并[a]芘之定量 分析。將該等之分析結果示於表1以及表2中。 [表1 ] 羧酸鹼金屬鹽 抽吸 次數 焦油 尼古丁 苯并[a]芘 mg/香菸 mg/香於 ng/香菸 1 ,一 % a) 比較例1 — 7.8 29. 3 3. 35 22. 1 實施例1 乳酸鉀 8. 2 28. 9 3.21 17. 4 -21 實施例2 乳酸鈉 8. 7 28. 8 3.28 17. 3 -22 實施例3 酒石酸_ 7. 7 26. 8 2. 91 17. 4 -21 實施例4 酒石酸納 8.4 27. 1 2.86 16. 2 -27 實施例5 琥珀酸鈉 9. 6 26.8 3.02 18.8 -15 a)相對於比較例1之增減率 IS 2] 叛酸驗金屬鹽 抽吸 焦油 尼古丁 苯并[a ] K ------- 次L mg/香菸 mg/香於 ng/香於 % a) 比較例2 — 7. 6 25. 1 2. 72 13. 9 實施例6 -- 實施例7 ' *---- ___^施例8 ------ 施例9 '----- 例 10 〜----- 3-羥基丁酸鈉 9. 2 27. 4 2. 72 12. 3 -12 乙酸钟 -----—_ 8.2 24. 6 2. 88 11.9 -15 乙酸鈉 9. 3 24. 6 2. 92 11. 6 -17 曱酸_ 8.5 23. 5 2. 78 11.1 -20 曱酸鈉 9.3 23. 5 2. 83 10. 7 -23 a)相對於比較例2之增減率 、，由表1可明顯得知，實施例1至5之香菸，每支的苯 并[a]芘之量相對於比較例1之香菸係減低15%至27%。並 12 321723 201032738 且，如表2所示，實施例6至10之香於，相較於比較例2 之香菸，儘管抽吸次數增加，其苯并[a]芘之量仍減低12 至23%。在表1、2之任一結果中，焦油以及尼古丁之量幾 乎沒有變化。因此，該等之結果顯示，本發明所使用之羧 酸金屬鹽選擇性地減低香菸主流煙中的苯并[a]芘之量。 實施例11至16 在該等實施例中，對乳酸鉀之添加量（相對於去梗菸葉 絲之重量的重量％ ;以下簡稱為「添加量」）進行檢討。 m 菸草充填材係準備由黃色種與伯萊種的非膨化去梗菸 葉絲、膨化之去梗菸葉絲以及中肋所構成之混合菸草a及 B。混合菸草A及B係菸草絲的種類與調配比例不同。在調 製該等混合菸草時，一邊將非膨化絲與膨化絲之混合物 10kg以混合器授拌，一邊以喷霧喷嘴（spray nozzle)將乳 酸鉀水溶液噴霧。結束喷霧後，將混合物以大型乾燥機乾 燥，並調配中肋而製得混合菸草。相對於去梗菸葉絲（非膨 _ 化之去梗菸葉絲+膨化之去梗菸葉絲）之乳酸鉀的添加量係 如表3所示。 使用以表3所示之量（每支香於申' 的由巍作法所 調製之混合菸草A或B，香菸捲紙係使用一般的捲紙，濾 嘴係使用纖維素乙酸酯濾嘴，裝接紙係使用一般的裝接 紙，經由香菸製造機製得附有濾嘴之香菸條。各香菸條之 長度為57mm，香於條之圓周長為25mm，遽嘴長度為27mm。 比較例3以及4 i & 未添加乳酸鉀之混合菸草A、Β係分別使用以表3所示 13 321723 201032738 之量，並與實施例11至16同樣製作香終。 [表3]= Second, there have been many records on the technology that makes the fragrance in the mainstream smoke, and the technique of reducing the amount of the agent is also added to the ash WO20G4/11 coffee.纠 际 公开 公开 _ _ _ _ _ _ 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 424 The amount of PaHs) is reduced by 1. However, because Ji and Ming and Jin are both expensive precious metals, they are disadvantageous in terms of the right to power. Moreover, she is a precious metal with a small amount of burial. In addition, since it has a high catalytic function, it is in demand in the automotive and semiconductor industries, and is therefore disadvantageous in terms of scheduling. Further, the metal carboxylate is conventionally intended to reduce the amount of carbon monoxide in the mainstream smoke of cigarettes. For example, in U.S. Patent No. 44,897,391, a tobacco composition containing an acid-reducing metal salt in an amount of from 6.5 to 20% in order to reduce the amount of carbon oxide produced. Japanese Patent Publication No. 2006-187260 discloses that in order to reduce the amount of carbon monoxide in the mainstream smoke of cigarettes, the organic metal salt and the inorganic alkali metal salt are formulated in a specific amount in the tobacco 3 321723 201032738 grass. . However, techniques for using an alkali metal carboxylate to reduce the amount of benzo[a]pyrene in the mainstream smoke of cigarettes have not appeared in the prior art. DISCLOSURE OF THE INVENTION [Problem to be Solved by the Invention] An object of the present invention is to provide a fragrance which reduces the amount of stupid [a] 主流 in mainstream smoke generated during smoking. [Means for Solving the Problem] The inventors of the present invention conducted a review of effective substances for reducing the amount of benzo[a]pyrene in mainstream cigarettes of cigarettes, and found that lactic acid, tartaric acid, succinic acid, and 3-hydroxyl groups were found. Various metal salts of butyric acid, acetic acid, and citric acid can selectively reduce the amount of benzo[a]pyrene in mainstream cigarettes of cigarettes. According to the present invention, there is provided a scent comprising a tobacco rod containing a tobacco filling material, wherein the grass filling material comprises stalked to the leaf and contains 0.5 to 6.0 of the weight of the stalk. a metal carboxylic acid salt selected from the group consisting of metal lactate, metal tartarate, metal succinate, metal 3-hydroxybutyrate, metal acetate, and metal formate Λ The metal carboxylate salt used in the present invention can selectively reduce the amount of benzo[a]pyrene in the mainstream smoke of cigarettes. Further, the metal carboxylate salt used in the present invention is substantially lower than palladium, and thus it is possible to provide a cigarette which is less expensive and which has reduced the mainstream smoke of benzo [a]. [Embodiment] 4 321723 201032738 The following 'Additional daily money (4). The filling material contains the material I which contains 2 secret herbs. The grass is stupid and his amount of Chu Jin and ^ have ^ reduce the mainstream smoke of the end of the tobacco to fill the rice filling, in general, the use of cigarettes in the Di...: silk (tobacco leaf shredded pork) ), tobacco ribs, regenerated in Zhuo Si or these in the early A job, jin mt b tb ID. The stalked tobacco leaves can be expanded or not subjected to ginseng = heavy t hair relative to the benzo (5) _ more de-stalk final Ϊ 卓 充 filling material contains a certain proportion of slow-acid metal salts. At the same time, the tissue of the dried and shrunk end of the shredded pork shreds is expanded by a rolled anti-four puffing agent. In the present invention, the metal salt is selected from the group consisting of a metal lactate, a tartar: a metal salt, a succinyl metal salt, a metal salt of a metal butyrate, a metal acetate, and a metal formate. The salt is preferably an alkali metal I. It is particularly preferred as a potassium salt or a sodium salt. The amount of 秘 0.5 to 6.0% by weight of the weight of the secret leaf of the metal salt of the present invention is contained in the grass filling material. When the amount of the new metal salt is less than 0.5% by weight, there is a tendency that the benzo [a] is not significantly reduced. The carboxylic acid metal salt is not more than 6.0. However, when the metal salt of citric acid is added in an amount of more than 6% by weight based on the weight of the stalked tobacco leaf, the reduction effect of benzo[a]pyrene is not significantly increased as compared with the addition of 6.0% by weight. The tendency to reduce the aroma of cigarettes is not good. The metal carboxylate is added in an amount of from 2 to 6% by weight based on the weight of the stalked tobacco leaf. ""... As mentioned above, the tobacco filling material used in the present invention contains puffed and /321723 5 201032738 (10) grass leaf shredded pork), and may also contain endophyta in Zhuo Si or such = a mixture of stalks, sputum, and/or re-synthesis in grasses or m Ο non-expanded stalked stalks and puffed stalks = stalks, or mixtures containing or Where:: and: ί:: silk and materials such as the middle ribs, the end of the grass, or the other materials (such as the weight of the grass filling material) One contains yellow species, burley species, and the like. . Adding a slow acid metal salt to the mixed early silk of the grass cultivar used in the grass cultivar to remove the stalk material (for example, the ribs, sorghum, and/or regenerated tobacco silk) He" 纟 纟 梗 终 终 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于 于In the case of leaves, the amount of the above-mentioned acid-lowering metal salt is preferably 0.5 to = of the total weight of the stalked stalks of the grass, which is composed of non-expanded, 糸 曰Adding to the mixture of 2 to 6 wt% silk of non-expanded de-stalking leaves, and preferably in the obtained mixed, puffed de-stalked terminal leaves or regenerated terminal grasses, thereby enhancing the benzene blending in the grass And / 丌 开 [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ [ The produced substance and the like are mixed in a solvent to form a public liquid, and == ink is formed on the grass sheet (one-(4), and the rafter can also be used as a secret grass material. _, will The metal lanthanum is added in the amount of 0.5.5% by weight (preferably 2 to 6% by weight) of the weight of the stalked tobacco leaf used in the filament of the grass. It may be added to the grass filling material. Perfume, for example: menthol can be added. The lysine metal salt can be contained in the grass filling material by any suitable method. For example, an aqueous solution of a metal salt of lysine is sprayed on the stalk leaf. The metal salt de-stalking silky sorghum filling material can be made after the thirst quenching. The scent of the present invention, except for the grass filling material, the tobacco filling material containing the metal carboxylate salt mentioned above can be used. The invention relates to a method for manufacturing a cigarette. The tobacco filling material containing the metal carboxylate of the invention is wound into a rod shape (generally cylindrical shape) by a cigarette paper roll. The fragrant final roll paper can be used in general. Any one of the linings of the pulp, such as flax, is used as a base paper. The fragrant paper is contained in a ratio of 2 g/m or more, such as carbonate, carbonic acid, etc., hydroxide #5, hydroxide lock. a filler commonly used for hydroxides. The agent may be contained in the cigarette paper in a ratio of 2 to 8 g/m 2 , and the scented roll paper generally has a basis weight of 22 g/m 2 or more. The basis weight is usually 80 g/m 2 or less. Air permeability is generally 1〇 to 60 CU (Coresta Unit) 〇7 321723 201032738 In addition, combustion regulators such as citric acid or its salts (sodium salt, potassium salt) can be added to cigarette paper. Usually, when using a combustion regulator In the case of cigarette paper, it is used in a ratio of 2% by weight or less. The present invention has the same structure and appearance as a general cigarette. Fig. 1 is an enlarged perspective view showing a cigarette of one type of the present invention. In Figure 1, cigarettes are not expanded in a certain proportion. The cigarette 10 shown in Fig. 1 includes a tobacco rod (a cylindrical rod in Fig. 1) containing a tobacco filling material containing a metal carboxylate salt of the present invention, and a cigarette roll wrapped with the final straw. The paper 122 has a cigabartte rod 12. The fragrance 12 has a circumference of 17 to 26 inches and a length of 49 to 90 mm. At the base end of the scented strip 12 (i.e., the downstream end of the smoking direction) 12a, a general tobacco filter 16 can be attached via a tipping paper 14. In the attachment paper 14 for diluting the mainstream smoke of the cigarette in order to take in the outside air, a vent hole (not shown) may be provided around the cigarette. The cigarette of the present invention can selectively reduce stupidity [a] in mainstream smoke. [Examples] Hereinafter, the present invention will be described in more detail by way of examples. Examples 1 to 5 In these examples, the metal carboxylate salt was an alkali metal carboxylate salt shown in Table 1, and the tobacco filler material was a stemmed yellow tobacco leaf. 5 g of the alkali metal carboxylate salt shown in Table 1 was dissolved in 20 ml of ultrapure water, and the solution was sprayed on 50 g of the de-stalked yellow tobacco leaf. Thus, the alkali metal carboxylate is added to the stemmed tobacco leaf in an amount of 5% by weight of the stemmed tobacco leaf. The de-stalked tobacco leaves to which the alkali metal carboxylate was added were conditioned in a room at 22 ° C for 8 hours, in a room temperature of 8 321 723, 201032738, and a humidity of 60% relative humidity for 48 hours or more. The tobacco strips were prepared by hand work using the stalked tobacco leaves and the usual cigarette paper. The amount of the straw-containing metal salt added to each cigarette rod was 735 mg, the length of the scent of the strip was 57 mm, and the circumference of the scent of the strip was 25 mm. A cellulose acetate tow (tow) is used as a filter material in a straw mouth (length: 27 mm), and is attached to one end of each of the cigarette rods via a binding paper having a vent hole. cigarette. Comparative Example 1 A cigarette was prepared in the same manner as in the examples 1 to 5, except that the alkali metal carboxylate salt was not added, and 700 mg of the de-stalked yellow tobacco leaf was used in the same manner as in the examples 1 to 5. Examples 6 to 10 In these examples, the metal carboxylate salt was a metal carboxylate metal salt shown in Table 2. 2 g of the alkali metal carboxylate salt shown in Table 2 was dissolved in 20 ml of ultrapure 10 water, and the solution was sprayed on 50 g of de-stalked yellow tobacco leaf. Thus, the alkali metal carboxylate is added to the tobacco filament in an amount of 5% by weight of the stemmed tobacco leaf. The tobacco filament to which the alkali metal carboxylate was added was subjected to the same humidity control as the two to 1 to 5. A cigarette was produced in the same manner as in Examples 1 to 5 except that the silk after conditioning was used. Comparative Example 2 A stalked yellow plant was used in the same manner as in the examples 6 to 10 except that the alkali metal carboxylate was not added, and the same operation was carried out to obtain a fragrance. 9 321723 201032738 <Measurement of the number of cigarettes to be smoked, and analysis of tar, nicotine and benzo[a]pyrene in cigarette mainstream smoke> A. Collection of particulate matter in cigarette mainstream smoke and determination of the number of times of suction : The cellulose acetate tow was removed from the filter of the cigarettes produced in Examples 1 to 10 and Comparative Examples 1 to 2, and the vent hole of the attachment paper was stoppered with a tape, and this was allowed to be operated. Smoking was carried out using a 10-line type smoker (SM410 manufactured by Cerulean) equipped with a granular material trap equipped with a Cambridge filter (pre-measured for this weight), and the particles were captured in a Cambridge filter. Shaped matter. The cigarette was pumped for 2 seconds per suction, with a suction capacity of 35 mL and a suction interval of 60 seconds. The cigarette was burned only to the front end of the cigarette to a length of 49 mm, the number of puffs of the cigarette was measured, and the average value of the cigarettes was calculated. The results are shown in Tables 1 and 2. B. Analysis of tar and nicotine The weight of the Cambridge filter trapping the above-mentioned particulate matter was measured, and the weight of the Cambridge filter previously measured was deducted from the weight to calculate the total weight of the granular material. 10 mL of isopropyl alcohol (containing quinoline or ethanol as an internal standard for analysis) was added to a Cambridge filter in which particulate matter was collected to extract a granular substance. For the extract, GC-FID/TCD (6890N manufactured by Agilent Co., Ltd.) was used to quantify the amount of water and nicotine by an internal standard method. The amount of tar is calculated by deducting the obtained water and the weight of nicotine from the total weight of the granular material. C. Benzo[a] analysis of the analysis 10 321723 201032738 Benzo[a] extension in Examples 1 to 10 and Comparative Examples 1 to 2 was carried out by mass spectrometry (GC_MS) method of gas chromatography as described below. The analysis was carried out in Examples U to 16 and Comparative Examples 3 to 4 described below using the following effect liquid chromatography (JJPLC) method. Cl: GC-MS method was carried out in the same manner as described above for the analysis of tar and nicotine to obtain an isopropyl alcohol extract of granular material. Into 6 mL of the extract, an internal standard solution (benzo[a] was added. A methanol solution of a heavy hydrogen substitute and 14 mL of ultrapure water were prepared to prepare a test solution. The test solution was packed in a cjj column (MEGABE-CH, 1GM6ML, manufactured by Varian Corporation). After the column was dried, it was eluted with 5 mL of cyclohexane. The eluate was placed in a Si column (Sep-Pak Vac 3 cc (500 mg), manufactured by Silica Cartridge, Waters Co., Ltd.), and washed with 5 mL of a mixed solvent of dichloromethane/cyclohexane (1/4). The eluate was concentrated and quantified by internal standard method using GC-MS (6890N manufactured by Agilent). 10 C-2 : HPLC method cyclohexane was added to a Cambridge filter in which the above-mentioned particulate matter was collected, and the concentration of the particulate matter was about vortexed for 30 minutes and then extracted. After the extract was filtered through a ruthenium membrane of 0.45 /zm, it was collected using a glass syringe connected to a solid phase extraction tube (86 mouth-?>3^2 21131 manufactured by soild-phase extraction cartridge XWater). The filtrate of 81111 <<>> was recovered through an extraction tube. The extraction tube used was purged with 7 mL of hexane, and the cleaning solution was combined with the recovered filtrate. 'The liquid of the Buddha's liquid was dried and then dissolved in 1 mL of acetonitrile' using 11 321723 201032738 (series 1000, manufactured by HEWLETT PACKARD) and supplied to benzo[a] by the absolute calibration method. Quantitative analysis of 芘. The analysis results of these are shown in Table 1 and Table 2. [Table 1] The number of times of alkali metal carboxylate pumping tar nicotine benzo [a] 芘 mg / cigarette mg / fragrant in ng / cigarette 1, 1% a) Comparative Example 1 - 7.8 29. 3 3. 35 22. 1 Example 1 Potassium lactate 8. 2 28. 9 3.21 17. 4 -21 Example 2 Sodium lactate 8. 7 28. 8 3.28 17. 3 -22 Example 3 Tartaric acid _ 7. 7 26. 8 2. 91 17. 4 -21 Example 4 Sodium tartrate 8.4 27. 1 2.86 16. 2 -27 Example 5 Sodium succinate 9. 6 26.8 3.02 18.8 -15 a) Increase or decrease rate relative to Comparative Example 1 IS 2] Oretest metal salt Aspiration of tar nicotine benzo[a] K ------- L mg / cigarette mg / fragrant in ng / fragrant in % a) Comparative Example 2 - 7. 6 25. 1 2. 72 13. 9 Implementation Example 6 - Example 7 '*---- ___^ Example 8 ------ Example 9 '----- Example 10~----- 3-hydroxybutyrate sodium 9. 2 27. 4 2. 72 12. 3 -12 Acetic acid clock ----- _ 8.2 24. 6 2. 88 11.9 -15 Sodium acetate 9. 3 24. 6 2. 92 11. 6 -17 Tannic acid _ 8.5 23. 5 2. 78 11.1 -20 Sodium citrate 9.3 23. 5 2. 83 10. 7 -23 a) Compared with the increase and decrease rate of Comparative Example 2, it can be clearly seen from Table 1, Examples 1 to 5 Cigarette, the amount of benzo[a]pyrene relative to each The cigarettes of Example 1 were reduced by 15% to 27%. And 12 321723 201032738 and, as shown in Table 2, the fragrance of Examples 6 to 10 is compared with the cigarette of Comparative Example 2, although the number of puffs is increased, the amount of benzo[a]pyrene is still reduced by 12 to 23 %. In any of the results of Tables 1 and 2, the amount of tar and nicotine remained almost unchanged. Thus, the results show that the metal carboxylate salt used in the present invention selectively reduces the amount of benzo[a]pyrene in mainstream cigarette smoke. Examples 11 to 16 In these examples, the amount of potassium lactate added (% by weight relative to the weight of the stemmed tobacco leaf; hereinafter referred to as "addition amount") was reviewed. m Tobacco filling material is prepared from mixed tobaccos a and B composed of yellow seeds and non-expanded stalked tobacco leaves of Burley species, expanded stalked tobacco leaves and middle ribs. The types of blended tobacco A and B tobacco silk are different from the blending ratio. In the preparation of the mixed tobacco, 10 kg of a mixture of the non-expanded filament and the expanded filament was mixed with a mixer, and a potassium lactic acid aqueous solution was sprayed with a spray nozzle. After the spraying was completed, the mixture was dried in a large dryer, and the middle ribs were blended to prepare a mixed tobacco. The amount of potassium lactate added relative to the stemmed tobacco leaf (non-expanded stemmed silk + expanded pruned tobacco leaf) is shown in Table 3. The mixed tobacco A or B prepared by the method described in Table 3 (each of which is fragrant) is used, the cigarette paper is a general roll paper, and the filter is a cellulose acetate filter. The attached paper uses a general attachment paper, and the cigarette strip with the filter is attached via a cigarette manufacturing mechanism. The length of each cigarette strip is 57 mm, the circumference of the strip is 25 mm, and the length of the mouth is 27 mm. Comparative Example 3 And 4 i & mixed tobacco A and potassium which were not added with potassium lactate were used in the amounts shown in Table 3, respectively, 13 321723 201032738, and the same fragrances as in the examples 11 to 16 were produced. [Table 3]
對於實施例11至16以及比較例3至4所製得之香終： 以與上述㈣之做法測定絲之抽吸次數、香終主流 煙^的焦油以及尼古丁之量，並依HPIX法敎苯并[^ 之置。將結果示於表4以及表5。For the fragrances prepared in Examples 11 to 16 and Comparative Examples 3 to 4: the number of times of suction of the silk, the amount of tar and the amount of nicotine of the mainstream cigarettes, and the amount of nicotine according to the HPIX method were determined in the same manner as in the above (4). And [^ set. The results are shown in Table 4 and Table 5.
321723 14 201032738 [表5] 乳酸卸之添加量 (%) 抽吸 次數 焦油 尼古丁 苯并[a]芘 mg/香菸 mg/香菸 ng/香於 % a) 比較例4 0 j 6. 9 22.2 1. 62 19. 1 實施例14 1.1 ] 6. 7 21. 0 1. 54 17. 8 — -7 實施例15 3. 2 6. 9 19. 9 1. 55 15. 5 -19 實施例16 5. 3 6. 9 18. 7 1.47 14. 5 _ -24 a)相對於比較例4之增減率 由表4以及表5可知，所有實施例皆確認苯并[a]芘量 的減低。然而，依混合菸草之種類，當乳酸鉀之添加量低 時，可看出苯并[a]芘之減低效果的差異。在使用混合菸草 A進行檢討之實施例η至13中，即使乳酸鉀之添加量為 0.5% ’亦可得到17%之苯并[a]芘量的減低率。另一方面， 在使用混合菸草B進行檢討之實施例14至16中，乳酸鉀 之添加量低至1.1%時，苯并[a]芘量之減低率低。其結果 響係暗示依所使用之原料及其調配比例而會有乳酸钟之效果 不同的可能性。 由上述之結果可認為，發揮苯并[a]芘之減低效果的乳 酸鉀之添加量必須為〇.5至6%左右。然而，由於認為因混 合於草之原料及其調配比例而使添加所致之減低效果不 同’故添加量係以2至6%為更佳。 【圖式簡單說明】 第1圖係大略呈示本發明之一種型態的香菸之放大透 視圖。 321723 15 201032738 【主要元件符號說明】 10 香於 12 香终條 12a 香於條之基端 14 裝接紙 16 菸草濾嘴 121 菸草條 122 香於捲紙 16 321723321723 14 201032738 [Table 5] Addition amount of lactic acid unloading (%) Number of puffs tar nicotine benzo [a] 芘 mg / cigarette mg / cigarette ng / fragrant in % a) Comparative Example 4 0 j 6. 9 22.2 1. 62 19. 1 Example 14 1.1 ] 6. 7 21. 0 1. 54 17. 8 — -7 Example 15 3. 2 6. 9 19. 9 1. 55 15. 5 -19 Example 16 5. 3 6. 9 18. 7 1.47 14. 5 _ -24 a) The increase and decrease ratio with respect to Comparative Example 4 is shown in Table 4 and Table 5. All the examples confirmed the decrease in the amount of benzo[a]. However, depending on the type of mixed tobacco, when the amount of potassium lactate added is low, the difference in the reduction effect of benzo[a]pyrene can be seen. In Examples η to 13 in which the mixed tobacco A was used for evaluation, even if the amount of potassium lactate added was 0.5% ', a reduction rate of 17% of benzo[a] hydrazine was obtained. On the other hand, in Examples 14 to 16 in which the mixed tobacco B was used for review, when the amount of potassium lactate added was as low as 1.1%, the reduction rate of the amount of benzo[a]pyrene was low. The result suggests that there may be different possibilities for the effect of the lactic acid clock depending on the materials used and the ratio of the ingredients used. From the above results, it is considered that the amount of potassium lactic acid which exhibits a reduction effect of benzo[a]pyrene must be from about 5% to about 6%. However, since the effect of the addition due to the mixing of the raw materials of the grass and the blending ratio is considered to be different, the addition amount is preferably from 2 to 6%. BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is an enlarged perspective view showing a cigarette of one type of the present invention. 321723 15 201032738 [Key symbol description] 10 Fragrance in 12 Fragrance end 12a Fragrance at the base end 14 Attachment paper 16 Tobacco filter 121 Tobacco strip 122 Fragrant on roll paper 16 321723