200934539 九、發明說明 【發明所屬之技術領域】 " 本發明係有關劑量計數器。 【先前技術】 如傳統上已知，計量吸入器係用來處理氣喘之處理器 。乾燥粉末吸入器（DPI )及計量吸入器（MDI ) _ 係此種吸入器之已知例子。計量吸入器亦周知爲按壓 0 式計量吸入器（PMDI )。 一般說來，計量吸入器包含含藥劑之氣溶膠罐。氣溶 膠罐一般包含：罐體；閥桿，自罐體延伸；以及彈簧，裝 入罐體內。藉彈簧彈壓以關閉閥桿，且當抵抗彈簧之彈力 而按壓時，釋出氣溶膠。閥桿普通藉附裝於計量吸入器之 氣溶膠罐保持。病患手動按壓罐體之底部而將閥桿推入罐 體內。自閥桿釋出之含藥劑氣溶膠通過殻體內部的通道， 0 俾自附裝於殼體之吸嘴排出。 設有劑量計數器以顯示劑量數之計量吸入器業已周知 。劑量計數器爲電子型（例如日本專利JP-T-2007-513666 )或機械型（例如日本專利JP-T-2003-512265及美國專利 6,446,627 )。從成本的觀點看來，機械型劑量計數器較昂 貴的電子型劑量計數器更有利。機械型劑量計數器在提供 可拋棄式計量吸入器上亦很有利。 習知機械型劑量計數器包含：指示器面板，帶有標誌 以指示劑量數，並可旋轉地被支承著；以及控制桿，用以 -5- 200934539 旋轉指示器面板。藉諸如彈簧之彈性手段迫使控制桿回到 初始位置。當手動按壓氣溶膠罐之罐體時，氣溶膠罐上的 壓縮力量抵抗控制桿之彈簧之彈壓力量，向下推移控制桿 °在氣溶膠罐上的壓縮力量解除時，控制桿彈回原來位置 。控制桿啣合指示器面板且使其旋轉預定角度，同時被按 壓或回到原來位置。亦即，於往復移動之一行程中，控制 桿旋轉指示器面板，令顯示加一。 然而，一直期望有使用氣溶膠罐之性質作爲機械型劑 量計數器之計量吸入器的進一步改良。 本發明提供使用氣溶膠罐之性質之改良計量吸入器。 【發明內容】 根據本發明之一態樣，提供一種計量吸入器，包括： 殼體； 氣溶膠罐，包含罐體、閥桿以及彈壓該閥桿之彈簧， 其中該閥桿被保持於該殼體內部之固定位置，且其中該罐 體被支承於該殼體內部，可抵抗彈簧之彈力而按壓； 劑量計數器，包含被可旋轉地支承於該殼體內部之顯 示構件以及被可擺動地支承於該殼體內部以旋轉該顯示構 件之控制桿；以及 控制蓋，包含被可旋轉地連結於控制桿之至少一個連 結構件以及自該罐體之底側覆蓋該罐體之蓋部，其中該控 制蓋藉由使用該氣溶膠罐之彈簧之彈力，使該控制桿擺動 並退回。 -6- 200934539 藉此配置，計量吸入器之構造可因使用氣溶膠罐之彈 力而簡化。 ' 計量吸入器可進一步包括移除手段，用以從控制桿移 除控制蓋之至少蓋部。例如，此移除手段可於連結構件與 蓋部之間包含有脆弱部，以自連結構件切斷蓋部。此脆弱 部可爲薄壁部。替帶地，此移除手段可包含連結構件，其 可折彎以切斷連結構件與控制桿間之連接。 I 計量吸入器可進一步包括：吸嘴，可卸除地附裝於殼 體；以及吸嘴蓋，覆蓋吸嘴；其中，此吸嘴蓋包含操作移 除手段之突起。殼體可包含移除手段，該移除手段具有藉 突起扎刺之薄膜部。又，計量吸入器可改成此殻體包含通 孔’當吸嘴蓋附裝於吸嘴時，此突起透過通孔刺入殼體； 以及’此突起透過通孔刺入殻體，以限制氣溶膠罐之按壓 位移。 計量吸入器可改成此劑量計數器進一步包括退回控制 Φ 桿之輔助彈簧。輔助彈簧之彈力並無限制。例如，輔助彈 簧本身雖具有不足以退回控制桿之彈力，卻夠強而可藉助 於氣溶膠罐之彈簧之彈力以退回控制桿。此—彈簧可安裝 於計量吸入器之上述第二發明。 此計量吸入器可改成進一步包括： 吸嘴，附裝於該殼體； 吸嘴蓋，覆蓋該吸嘴； 鎖緊機構’當該吸嘴蓋附裝於該吸嘴時，限制該氣溶 膠罐之按壓位移； -7- 200934539 其中，該吸嘴蓋包含突起，當該吸嘴蓋附裝於該吸嘴 • 時，該突起可通過該吸嘴之通孔刺入，且其中該鎖緊機構 •包含： 傾斜導面，沿蓋部之周圍形成於蓋部之下緣上； 以及 鎖緊構件，包含：傾斜面，藉由可滑動地爲該傾 斜導面所導引，該傾斜面可沿該傾斜導面移動；以及鎖緊 ©部，與該突起相互鎖扣，以防止該傾斜面之移動； 其中，該鎖緊構件藉由支承該傾斜導面於一位置 之該傾斜面上，限制該控制蓋之按壓位移，於該位置藉該 鎖緊部防止該傾斜面之移動；以及 其中該鎖緊構件自該突起釋放該鎖緊部，以容許 該傾斜面移動，並藉此容許控制蓋之按壓位移。 根據本發明之第二態樣，提供一種計量吸入器，包括 _ 氣溶膠罐，包含罐體、自該罐體延伸之閥桿以及彈壓 該閥桿之彈簧，該閥桿被按壓以釋放該氣溶膠罐之內容物 t 殼體，設有夾持該氣溶膠罐之閥桿之夾持具，以收容 該氣溶膠罐； 劑量計數器，包含：至少一個顯示構件，被可旋轉地 支承於該殼體內部；及控制桿，被支承於該殻體內部，以 旋轉該顯示構件；以及 控制蓋’包含：至少一個連結構件，可啣合該控制桿 -8 - 200934539 ;及蓋部，自該閥桿之相對側覆蓋該罐體； 該氣溶膠罐被支承於該殼體中，使該罐體可抵抗該彈 簧之彈壓力被按壓； 該氣溶膠罐之該罐體包含啣合該控制桿之啣合部； 該控制桿可移動於第一位置與第二位置之間，該第一 位置係該閥桿頂端與該啣合部間之預定位置，且該第二位 置係與該罐體之該啣合部啣合之該控制桿的按壓位置； 該控制蓋與該罐體合作，被自該第一位置按壓，並藉 該氣溶膠罐之彈簧，與該罐體合作，自按壓位置回到初始 位置； 當該罐體隨著該控制蓋被按壓時，該罐體之該啣合部 與該控制桿啣合，將該控制桿自該第一位置移動至該第二 位置； 當回到該初始位置時，該控制蓋之該連結構件將該控 制桿自該第二位置移動至該第一位置；以及 該控制桿在自該第一位置移動至該第二位置時，或在 自該第二位置回到該第一位置時，旋轉該顯示構件。 藉此配置，計量吸入器之構造可因使用氣溶膠罐之彈 力而簡化。控制桿之形狀並無限制。例如，控制桿可設有 與氣溶膠罐啣合之啣合部。氣溶膠罐不常直接接觸控制桿 。氣溶膠罐可透過其他構件，間接接觸控制桿。 常因氣溶膠罐之製造誤差而有閥桿長度之變化。例如 ，相較於需要較短按壓距離之較短閥桿，具有較長閥桿之 氣溶膠罐會有需要自按壓點至內容物釋放之較長按壓距離 200934539 的傾向。 於本發明中，控制桿配設於罐體之啣合部與啣合部之 頂端間的預定位置。這在以下方面很有利。例如，藉此配 置，較長閥桿需要較長按壓距離來使罐體於按壓後與控制 桿啣合，而較短閥桿需要較短按壓距離來使罐體於按壓後 與控制桿啣合。藉由利用閥桿長度與排出所需按壓距離間 的關係，罐體之啣合部與控制桿啣合後之排出內容物用按 壓距離可不管閥桿長度如何，實質上相同。亦即，即使閥 桿長度有變化，自排出內容物至藉控制桿操作之劑量計數 器之更新爲止的時間仍可實質上相同，俾病患不必因閥桿 長度不同而注意時間滯後。 計量吸入器可改成此控制桿在自第二位置回到第一位 置時，與此顯示構件啣合，並旋轉此顯示構件。 計量吸入器可改成此控制桿包含止動件，此止動件將 顯示構件鎖定於第一位置，並在第二位置解開顯示構件。 藉此配置，當控制桿處於初始之第一位置時，鎖死顯示構 件之旋轉，防止顯示構件之偶然旋轉及劑量計數器的故障 〇 控制桿可具有例如以下各種配置。控制桿可配置成其 包含突起，該突起可與連結構件啣合，並可擺動地支承於 第一位置與第二位置之間； 其中，此控制桿響應控制蓋之按壓，自第一位置擺動 至第二位置，且其中，此連結構件與此突該起響應控制蓋 之按壓，不相互啣合地隨著控制桿之擺動一起移動；以及 -10- 200934539 其中，當藉控制蓋移動而回到初始位置時’此連結構 件藉由與突起啣合，將控制桿自第二位置移動至第一位置 〇 又，計量吸入器可改成此罐體於具有此閥桿之表面上 包含有梯級部，且其中，此梯級部包括啣合部。啣合構件 不限於梯級部，只要其能藉由啣合控制桿，推壓控制桿即 可。 I 又，計量吸入器可改成進一步包含：吸嘴，可卸除地 Ο 附裝於此殻體；其中，此氣溶膠罐之內容物透過此吸嘴， 自此殼體排出。藉由設置吸嘴，可直接將自氣溶膠罐之排 出之內容物送至口中。 又，計量吸入器可改成進一步包含自此閥桿之一側支 承此罐體之支承手段。這防止當罐體因撞擊力量或在吸入 器組裝期間藉蓋部關閉罐體的過程中不小心按壓時，發生 罐體的移動及計數器的前進。 ❿ 有利效果 藉根據本發明之計量吸入器，可減少吸入所需氣溶膠 罐之壓縮力量。 【實施方式】 用以實施本發明之最佳模式 以下將說明根據本發明實施之計量吸入器之實施例。 -11 - 200934539 第一實施例 以下將參考第1至第17圖，說明根據本發明實施之 計量吸入器之第一實施例。 如第1圖所示，計量吸入器1包含殼體2以及容納於 殼體2內的氣溶膠罐3。如第2圖所示，吸嘴4附裝於殼 體2’且吸嘴蓋5可卸除地設於吸嘴4。 如第3及4圖所示，氣溶膠罐3包含：罐體3a，大致 _ 呈圓柱形；以及閥桿3b，突伸入罐體3a之一端。藉其所 0 含盤簧（未圖示），沿突出方向彈壓閥桿3b，俾閥保持關 如第5圖所示，殼體2包含圓柱部2a，以收容氣溶膠 罐。如第3圖所示，閥桿3b面朝下，將氣溶膠罐3上下 倒置插入殼體2內。參考第5圖，殻體2內包含夾持具2b ，用以夾閥桿3b。夾持具2b內包含裝配孔2bl，其形成 來氣密裝配閥桿3b。殻體2進一步：孔口 2c，與裝配孔 g 2bl連通；以及漏斗部2d，與孔口 2c連通。透過漏斗部 2d，自閥桿3b釋出之氣溶膠被導入吸嘴4。 抵抗內部盤簧（未圖示）之彈力而按壓氣溶膠罐3之 罐體3a，將閥桿3b推入氣溶膠罐3內，開啓閥桿3b之閥 ，藉此容許藥劑進入閥桿3b，接著，透過孔口 2c及漏斗 部2d將氣溶膠釋入吸嘴4。 參考第3及4圖，劑量計數器10設於殼體2內部。 劑量計數器1〇包含：支承構件11，固定於殻體2之內表 面；一對顯示構件12及13，可旋轉地被支承構件11所支 -12- 200934539 承；以及控制桿14，用來旋轉顯示構件12及13。 例如’ 0至1 〇之十位數以規則間隔印在顯示構件1 2 之圓周側面。同樣地’ 0至9之個位數以規則間隔印在顯 示構件1 3之圓周側面。因此，劑量計數器1 〇可顯示數目 0至109。如於第1及2圖所示，於殼體2之側面形成窗 口 2w，透過該窗口 2w可觀看顯示構件12及13上的數目 (未圖不）。 如於第6及7圖中的爆炸立體圖所示，顯示構件12 及13係分別具有軸孔12a及13a之環形環。 第8圖係第6圖之局部放大立體圖。第9圖係第7圖 之局部放大立體圖。參考第8圖，顯示構件12包含複數 個圓周鎖緊溝槽1 2a，形成於其與顯示構件1 3相向的一側 。如於第9圖所示，支承構件1 1包含與鎖緊溝槽1 2a相 互鎖扣之止回爪11a。止回爪11a與鎖緊溝槽12a設成， 止回爪11a防止顯示構件12沿箭頭A方向旋轉，不過， 藉由具有彈性，容許當一預定轉矩沿該方向施加於顯示構 件12時，顯示構件12沿箭頭B方向旋轉。 第10圖係第7圖之局部放大立體圖。第11圖係第6 圖之局部放大立體圖。於第10及11圖中，爲便於解釋， 省略設於支承構件1 1與顯示構件1 3間之顯示構件1 2。 如於第10圖所示，於顯示構件13之軸孔13a之內周 面上形成複數個沿軸向延伸之等角度鎖緊溝槽13b。支承 構件11包含與鎖緊溝槽13b相互鎖扣之止回爪lib。鎖緊 溝槽13b與止回爪lib設成，止回爪lib防止顯示構件13 -13- 200934539 沿箭頭A方向旋轉’不過，藉由具有彈性，容許當一預定 轉矩沿該方向施加於顯示構件1 3時，顯示構件1 3沿箭頭 B方向旋轉。 如於第10圖所示，顯示構件13進一步包含複數個圓 周鎖緊溝槽13c，形成於其與顯示構件12相向的一側。控 制桿14藉形成於支承構件11上之軸11c可擺動地支承。 控制桿14之頂端係與鎖緊溝槽13c相互鎖扣之鎖扣爪14a (第11圖）。當沿箭頭方向B1擺動時，控制桿14隨著 與鎖緊溝槽13c相互鎖扣之鎖扣爪14a擺動，施加預定轉 矩於顯示構件13’並使其沿箭頭B方向旋轉。當控制桿 14沿箭頭A1方向擺動時，鎖扣爪14a在顯示構件13之 傾斜面13d上滑動（第1〇圖），此乃因爲止回爪nb防 止顯示構件13沿箭頭A方向之旋轉。於控制桿14之一行 程中，顯示構件13旋轉60°。 如於第9圖所示’顯示構件13於其與顯示構件13接 觸之一側包含有複數個圓周鎖緊溝槽12c。參考第11圖， 顯示構件13包含可與鎖緊溝槽i2c相互鎖扣之鎖扣爪i3e 。如於第1 〇圖所示，鎖扣爪1 3在與顯示構件1 2相向之 —側具有突起13f。突起I3f設成，如屬於第6圖之局部 放大圖之第12圖所示’沿形成於殻體2之一部分2y之內 側之隆起部2k向上滑動。當顯示構件1 3旋轉而將顯示自 “9”變成“0”時’鎖扣爪13e之突起13f沿隆起部2k 向上滑動’將鎖扣爪13e推向鎖緊溝槽i2c，使鎖扣爪 13e與鎖緊溝槽12c之一相互鎖扣，顯示構件12隨著顯示 -14 - 200934539 構件13旋轉’藉此，推進顯示構件12上的十進位 起13f未向上到達鎖緊溝槽12c上時，鎖扣爪I3e 緊溝槽12c相互鎖扣。因此，透過窗口 2w顯示之 數器之數目增加。 參考第13圖之局部放大視圖，控制蓋20包含 結構件20a，可旋轉地連結於控制桿14 ;以及蓋部 其自蓋底3a之底側覆蓋蓋底3a。 蓋部20b可包含：底板20bl，可與氣溶膠罐之 觸；以及殼20b2，圍繞氣溶膠罐之周壁。殼20b2 輪從動件20c。凸輪從動件20c與形成於殼體2之 上之凸輪溝槽2e (第1圖）啣合。凸輪溝槽2e沿 之圓柱部2a (第5圖）之軸向延伸，以導引控制蓋 往復移動。 在此須知，圖示之蓋部20b係兩件式構件，包 第6及7圖連結在一起之上部（底板）20bl與下部 20b2。這是爲了製造方便，且蓋部2 0b可爲單件式 如於第13圖所示，連結構件2 0a包含形成於突 一端之鉤部，該突起20d自蓋部2 0b之殼20b2之 出。參考第1〇及1 1圖，控制桿14在鎖扣爪14a 收容軸1 lc之孔14b之間包含有一連桿銷14c。如方 及15圖所示，控制桿14藉由連結構件20a之鉤部 銷14c之啣接，可旋轉地連結於連結構件2 0a。因 制蓋20之垂直往復移動使控制桿14前後擺動，並 示構件1 2。 。當突 不與鎖 劑量計 :一連 20b， 底部接 包含凸 內周面 殼體2 20之 含有如 (殼） 奪件。 起20d 下緣伸 與用以 令第14 與連桿 此，控 旋轉顯 -15- 200934539 請注意連結構件20a不限於圖式所示構形’只要可旋 轉地連結於控制桿14即可。例如，連結構件可爲連桿銷 ，且控制桿可包含供連桿銷裝配之銷孔。 如於第13圖所示，除了連結構件20a外’形成另一 連結構件20a’。設置連結構件20a’以連結於具有不同擺動 角之之控制桿14’（請參閱第16及17圖）。控制桿14’包 含連桿銷14c’及孔14b’，其等相較於控制桿14，彼此更 ^ 隔得更遠。如此，若控制蓋20之往復行程相同，控制桿 〇 1 4 ’即擺動較控制桿1 4更小的角度。例如，可藉由裝配此 等構件於連結構件20a’或連結構件20a，分別適當使用具 有較小角度之控制桿1 4 ’及具有較大角度之控制桿1 4於成 人及小孩。 如於第10及11圖所示，控制桿14包含止動件14s， 其防止當控制桿14不擺動時，顯示構件12及13意外旋 轉。止動件14s包含突起14sl，該突起14sl與等角度形 φ 成於顯示構件12、13之周面上的凹穴I2x(請參閱第9圖 )啣合。 參考第13圖，控制蓋20包含一脆弱部20e，用來使 蓋部20b與連結構件20a相互分離。如圖示，脆弱部2〇e 可爲由橫向溝槽形成之薄壁部’該橫向溝槽沿突起20d之 寬度形成。脆弱部2 0 e並未特別限制，只要夠強而能防止 於控制桿1 4正常操作期間折斷即可。例如，脆弱部2 〇 e 可藉由減少寬度而非如圖所示厚度形成。 如第2圖所示，吸嘴蓋5可具有突起5a，用來折斷脆 -16- 200934539 弱部20 e。雖然使用突起5a較佳，惟可藉其他手段或方法 折斷。替代地，連結構件20a可設有鉸鏈。藉此構形，當 向內推壓突起5a時，連結構件與控制桿間之連接可藉由 向內彎折連結構件2〇a切斷。例如，由第6及7圖所示之 兩部2x及2y裝配之殼體2可構成包含可卸除部2y，俾使 用者可用指甲手動折斷脆弱部20e。 如於第3、4及7所示，殻體2包含一可藉突起5a扎 刺之薄膜部2f。突起5a扎刺薄膜部2f並碰撞控制蓋20 之脆弱部20e稍下方之部分’而於脆弱部20e造成折斷。 較佳地，突起5a具有推進端，俾其可容易扎刺薄膜部2f 。可設置打孔部來替代薄膜部2f。 殼體2包含一通孔2g (第5圖），當吸嘴蓋5附裝於 吸嘴4時，突起5 a經該通孔2 g刺入殼體2。如第3圖所 示，突起5a經該通孔2g刺入殻體2，並抵緊於設在控制 蓋20之殻20b2之邊緣上之舌片20f (第6圖）上。這避 Λ 免氣溶膠罐3之控制蓋20及罐體3a之按壓’以防止故障 φ 。亦即，在吸嘴蓋5附裝於吸嘴4下，無法按壓氣溶膠罐 3。請注意，雖未圖示’突起5a可適用來直接抵緊於氣溶 膠罐3上，以限制氣溶膠罐3之按壓位移。 爲起動計量吸入器’須自吸嘴4移除吸嘴蓋5。以下 參考第14及15圖，討論計量吸入器之操作。 第14圖係罐體3a被壓入殼體2前之部分切除立體圖 〇 於第1 4圖所示狀態中，止動件1 4 s與顯示構件1 2、 -17- 200934539 13啣合’以防止顯示構件12、13旋轉，從而防止故障。 例如’以止動件14s抑制藉由透過殻體2之窗口 2w接近 ，旋轉顯示構件12、13之企圖。 第15圖係罐體3a已被壓入殼體2之狀態的部分切除 立體圖。 隨著吸嘴蓋5移除’使用者透過蓋部2〇b手動按壓， 抵抗內部盤簧（未圖示）’將氣溶膠罐3之罐體3a壓入 殼體2內。這造成連結於連結構件20a之控制桿14自第 14圖所示位置，向下擺動至第12圖所示下方位置。於此 下方位置’控制桿14之鎖緊爪14a與顯示構件13 (亦請 參考第10圖）之鎖緊溝槽13c相互鎖扣。 當氣溶膠罐3之罐體3a壓入殻體2內時，在反應下 ’閥桿3b被推入罐體3a內，容許藥劑進入閥桿3b，接著 釋出計量之含藥劑氣溶膠。含藥劑氣溶膠自閥桿3b，經孔 口 2c、漏斗部2d及吸嘴4(亦請參考第5圖）釋出外部 〇 在含藥劑氣溶膠釋出之後，透過蓋部2〇b施加於罐體 3a上之壓縮力量解除。在反應下，氣溶膠罐3之內部盤簧 隨著罐體3 a ’將控制蓋2 〇往後推。隨著控制蓋2 〇被往後 推，連結於控制蓋2 0之控制桿14自第1 5圖所示下方位 置擺動回到第1 4圖所示原來位置。當控制桿1 4回到原來 位置時’與鎖緊溝槽13c之一相互鎖扣之鎖緊爪14a使顯 示構件13旋轉預定角度。此旋轉預定角度係使顯示構件 13之顯示加一所需角度。請注意，隨著罐體3a回到原來 -18- 200934539 位置，閥桿3 b回到原來位置’並塡注藥劑供次一注射。 如以上說明，於第一實施例之計量吸入器1中’控制 桿14藉氣溶膠罐3之內部盤簧彈回。如此’計量吸入器1 可很簡單。 又，第一實施例之計量吸入器1由除了氣溶膠罐3之 十個組件構成。除了氣溶膠罐3之所有此等組件可藉由樹 脂成形形成。 Ο 當氣溶膠罐3中的藥劑在計量吸入器1中用完時’藉 突起5a折斷控制蓋20之脆弱部20e，使蓋部20b與連結 構件20a分離。由於蓋部20b簡單覆蓋氣溶膠罐3且不與 其啣合，因此，在蓋部20b與連結構件20a分離之後，蓋 部20b可迅速自殼體2拉出。替代地，當連結構件20a以 脆弱部20e作爲支點，繞其彎曲，俾控制桿14與連結構 件20a間的連接分斷時，蓋部20b迅速自殻體2移除。一 旦拉出蓋部20b，使用者即因閥桿3b簡單地插入夾持具 H 2b而可容易取出氣溶膠罐3。這使得金屬製氣溶膠罐3容 易分離’而自其他樹脂成形品形成之十個組件處理掉。 第二實施例 以下將參考第28圖說明根據本發明實施之計量吸入 器第二實施例。第二例子係第一實施例之修改。因此，以 下說明主要談到所作改變，而不對業已在第一實施例中說 明之諸兀件進〜步解釋。又，爲求容易了解，以相同元件 符號標示第一與第二實施例中的相同元件。 -19- 200934539 如於第18及19圖所示，第二實施例之 100包含一輔助彈簧101，其使控制桿退至初 助彈簧101本身之彈力雖不足以使控制桿140 強而可藉助於氣溶膠罐之彈簧之彈力（未圖示 桿1 4 0的退返。 由於氣溶膠罐3易發生製造誤差，因此， 簧101來補償氣溶膠罐3之尺寸變動，或氣溶 彈簧之彈力變動。如於圖式中所示，輔助彈簧 彈簧，安裝在支承構件110之軸110c上，朝 壓控制桿140 ^ 例如，有時候，閥桿3b (參閱第20圖） 3之罐體之垂直長度較所設計尺寸短，或氣溶 彈簧之彈力較期望小。於此等情況下，釋出氣 3b之按壓距離會比預期還小。因此，在彈壓閥 部彈簧中有較小的壓縮變形。於此情況下’彈 之彈簧之回彈力量可能較期望小，太小以致無 桿140。當退返時，控制桿140與顯示構件13 13c之一相互鎖扣以旋轉顯示構件13。在此， 件12、13之力量須夠強以造成止回爪Ua (參 、止回爪llb(參閱第10圖）或突起13f (參 )之彈性變形。當彈壓閥桿3 b之彈簧之回彈 成止回爪Ha或止回爪lib之彈性變形時’控 法退回。 當氣溶膠罐3因設計誤差而有變動時’輔 劑量計數器 始位置。輔 退返，卻夠 )造成控制 設置輔助彈 膠罐3之內 101係扭矩 初始位置彈 或氣溶膠罐 膠罐之內部 溶膠之閥桿 桿3b之內 !壓閥桿 3 b 法彈退控制 之鎖緊凹槽 旋轉顯示構 閱第9圖） 閱第10圖 力量不夠造 制桿140無 助彈簧1 0 1 -20- 200934539 協助氣溶膠罐之彈簧，確保控制桿140退回。換言之，設 置控制桿140以防止因氣溶膠罐3之製造誤差而故障。 輔助彈簧101係弱彈簧’本身無法彈退控制桿14〇。 因此，輔助彈簧不會添加令使用者難以按壓氣溶膠罐 3之大的額外負荷。彈力可設定爲其他力量。 爲補償氣溶膠罐3之尺寸誤差，如第20及21圖所示 ，第二實施例之計量吸入器構成包含一控制蓋200，其由 上部及下部之二組件形成，此二組件如以下組裝。請注意 ，上部係控制蓋200之蓋部200b之底板20 Obi，且下部由 控制蓋200之蓋部200b之殼200b2以及連結構件20a構 成。於裝配的最後步驟中，當閥桿3b裝配於夾持具2b之 壓配孔2bl (請參閱第5圖）時，將氣溶膠罐3插入下部 並保持於其內。在無施加於氣溶膠罐3之力量下，蓋、上 部放置於下部上方。於認出上部之內底面與氣溶膠罐3之 底面接觸時，上部藉由超音波或其他接合手段接合於下部 。以此方式裝配之控制蓋200可吸收氣溶膠罐之製造誤差 ，例如像是與所設計尺寸不一致之大或小的垂直尺寸。此 等構造可應用於上述實施例。 第二實施例之計量吸入器進一步包含一鎖緊機構，其 在吸嘴蓋附裝於吸嘴時，限制氣溶膠罐3之按壓位移。以 下參考第22圖至第28圖說明鎖緊機構。 參考第22圖至第28圖，控制蓋200之蓋部200b之 下緣具有多數隆起部202，每一隆起部202沿蓋部200b之 周圍具有傾斜導面20 1。參考第22圖至第28圖，鎖緊構 -21 - 200934539 件300設成包含多數直立部302，其每一者具有爲傾斜導 面201所滑動導引之傾斜面301。鎖緊構件300亦包含旋 轉軸303。旋轉軸3 03插入形成於支承構件1 10之軸孔（ 請參閱第18及19圖），以旋轉地支承鎖緊構件3 00於支 承構件110。當按壓控制蓋200時，傾斜導面201導引傾 斜面3 0 1，且當傾斜面3 0 1沿傾斜導面滑動時，鎖緊構件 300旋轉。 如於第22圖所示，鎖緊構件3 00包含一鎖緊突起304 〇 ’其與突起5a相互鎖扣以防止傾斜面30 1移動。如於第 22圖所示，在鎖緊突起3 04防止傾斜面301移動之位置， 傾斜面301支承傾斜導面201以限制控制蓋200之按壓位 移。如於第24及25圖所示，當吸嘴蓋5自吸嘴4 (請 參閱第2圖）移除俾從鎖緊突起3 04解除突起5a時，容 許傾斜面3 0 1之移動。當壓縮力施加於控制蓋2 0 0時，傾 斜面3 0 1沿傾斜導面2 0 1位移，且具有傾斜面3 0 1之直立 φ 部3 02移入緊鄰隆起部202上之凹穴203，藉此容許控制 盖200之按壓位移。如前述，於第二實施例中，當吸嘴蓋 5附裝於吸嘴4時，鎖緊機構限制氣溶膠罐3之按壓位移 。如於第一實施例所述，當附裝吸嘴蓋5時，亦藉與舌片 2〇f (請參閱第6圖）接觸之突起5a限制氣溶膠罐3之按 壓位移’以防故障。如此’於第二實施例中設置鎖緊構件 提供額外安全性，以防故障。 桌二實施例 -22- 200934539 以下將參考第29圖至第45圖，說明根據本發明實施 之計量吸入器第三實施例。 本實施例之計量吸入器被用來直接透過病患的嘴送服 氣溶膠藥劑。外觀基本上如於第一及第二實施例。具體而 言，如於第29圖所示，計量吸入器1包含：殼體2 ;氣溶 膠罐3，容納於殼體2內；以及控制蓋20，固定於氣溶膠 罐3之上端。又，如於第30圖所示，殼體2包含吸嘴4 以及放入病患嘴中之吸嘴蓋5。 氣溶膠罐3如上述實施例。具體而言，如於第31及 32圖所示，氣溶膠罐3包含：大體上圓柱形，容納藥劑之 罐體3 a，且小徑之圓柱形凸出3 C形成於罐體3 a之下端面 上。管狀閥桿3b自凸出（梯級）3c向下延伸。 如於第33圖所示，殼體2包含一圓柱部2a，其爲氣 溶膠罐3提供容納之所。如於第31圖所示，氣溶膠罐3 以閥桿3b面朝下，倒置插入殻體2。如於第33圖所示， 殼體2包含用以夾持閥桿3b之夾持具2b。夾持具2b包含 一裝配孔2bl，其形成來氣密裝配閥桿3b。殻體2進一步 包含：孔口 2c，與裝配孔2bl連通；以及漏斗部2d，與 孔口 2c連通。透過漏斗部2d，將自閥桿3b釋出之氣溶膠 導入吸嘴4。 抵抗內部盤簧（未圖示）之彈力按壓氣溶膠罐3之罐 體3a，將閥桿3b推入氣溶膠罐3，開啓閥桿3b之閥。這 造成閥桿3b透過孔口 2c及漏斗部2d，將計量含藥劑氣溶 膠釋入吸嘴4。 -23- 200934539 如於第31及32圖所示，殼體2包含一劑量計數器l〇 ，其計數吸入者使用次數。劑量計數器10之構形如同上 述實施例。 如第41圖之局部放大視圖所視，控制蓋20包含：連 結構件20a，可旋轉地連結於控制桿14 ;以及蓋部20b， 自罐體3a之底部覆蓋罐體3a。連結構件20a之構造異於 上述實施例。 蓋部20b可包含：底板20b 1，與氣溶膠罐之底部接觸 ;以及殼20b2，圍繞氣溶膠罐之周壁。殼20b2包含凸輪 從動件20c。凸輪從動件20c與形成於殼體2之內周面之 凸輪溝槽2e (第29圖）啣合。凸輪溝槽2e沿殻體2之圓 柱部2a (第33圖）延伸，以導引控制蓋20之垂直、往復 移動。 如於第41圖所示，連結構件20a係自蓋部20b之殼 20b2之下緣伸出之鉤形 （J形）構件。如於第38及39 圖所示，控制桿14於鎖扣爪14a與用以收容軸1 lc之孔 14b間包含有連桿銷（突起）14c。如於第42及43圖所示 ，控制桿14藉由連結構件20a與連桿銷14c啣合，可旋 轉地連結於連結構件20a °於連結構件20a之垂直移動中 ，連桿銷14c不與向下移動之連結構件20a啣合，而於向 上移動中，如稍後說明，連結構件20a與連桿銷14c啣合 ，並隨其移動，導致控制桿14於軸11c上擺動。 如於第3 8及3 9圖所示’水平延伸之接觸板14d形成 於控制桿14之連桿銷14c附近，亦即連桿銷14c與鎖扣 -24- 200934539 爪14a之間，俾與罐體3a之凸出3c接觸。一開始位於閥 桿3b之頂端與凸出3c間之接觸板14d在罐體3a藉由控 制蓋20之按壓下降時，被凸出3c推出，使控制桿14在 軸11c上擺動。如於第38及39圖所示，控制桿14包含 止動件14s，其防止當控制桿14不擺動時，顯示構件12 及13意外旋轉。此種防止顯示構件旋轉之構造與第一實 施例相同。 I 殼體2亦包含通孔2g (第5圖），透過該通孔2g， 〇 當吸嘴蓋5附裝於吸嘴4時，突起5a扎入殻體2。該構造 如於前述實施例中所述，且不進一步說明。 以下參考第42及43圖說明如以上構成之計量吸入器 之操作。爲起動計量吸入器須自吸嘴4移除吸嘴蓋5。 第42圖係部分切除立體圖，顯示罐體3a被壓入殼體 2前之初始狀態。於此狀態下，止動件1 4s與顯示構件1 2 、：13啣合以防顯示構件12、13故障。第43圖係部分切除 φ 立體圖，顯示被壓入殼體2之罐體3a。 於摘下吸嘴蓋5之後，病患將吸嘴4放入嘴中，或將 其支持於嘴前。病患接著手動按壓氣溶膠罐3之罐體3a， 經由蓋部20b，進入殼體2而抵住內盤簧（未圖示）。這 導致罐體3a之凸出3c與接觸板14d啣合，並在罐體3a 向下移動時，將接觸板14d往下推。結果，控制桿14自 第42圖所示位置向下擺動至第43圖所示下方位置。於此 下方位置，控制桿14之鎖扣爪14a與顯示構件13(亦參 閱第38圖）之鎖緊凹槽13c相互鎖扣。在此，連結於蓋 -25- 200934539 部20b之連結構件20a亦藉由按壓向下移動。惟由於控制 桿14向下擺動，因此，連結構件20a與控制桿14之連桿 銷14c兩者向下移動，而不相互啣合。 當氣溶膠罐3之罐體3a被按入殼體2內時，閥桿3b 釋出含藥劑氣溶膠。自閥桿3b，含藥劑氣溶膠自閥桿3b ，經孔口 2c、漏斗部2d及吸嘴4 (亦參閱第33圖）釋出 〇 於釋出含藥劑氣溶膠之後，透過蓋部20b施加於罐體 3a上的壓縮力解除。氣溶膠罐3之內盤簧響應而藉罐體 3a將控制蓋20往回推。當控制蓋20被往回推時，蓋部 2〇b之連結構件20a與連桿銷14c啣合，並隨著連桿銷 14c向上移動。結果，控制桿14自第43圖所示下方位置 擺動回到第4 2圖所示原來位置。當控制桿1 4回到原來位 置時，與鎖緊凹槽13c之一相互鎖扣之鎖扣爪14a使顯示 構件13旋轉預定角度。該預定旋轉角度係使顯示構件13 之顯示加一之角度。須知，隨著罐體3 a回到原來位置， 閥桿3b回到原來位置，且注滿藥劑供下次注射。 如以上說明，於本實施例中，控制桿1 4藉氣溶膠罐3 之內盤簧彈回。如此’計量吸入器之構造可很簡單。請注 意，輔助彈簧可如於第二實施例安裝。 經常因製造誤差而在閥桿之長度上有變動。例如，如 於第44圖所示，相較於需要較短按壓距離之具有短閥桿 之氣溶膠罐（第44(b)圖），具有長閥桿之氣溶膠罐（ 第44(a)圖）有需要自按壓點至內容物釋出點之較長閥 -26- 200934539 桿按壓距離的傾向。 相對地，於本實施例中，控制桿設有接觸板14d ’該 接觸板14d設在罐體3a之凸出3c與閥桿3b之頂端間之 —預定位置。這在以下方面很有利。例如’如於第45圖 所示，考慮具有長閥桿之氣溶膠罐（第45(a)圖）及具 有短閥桿之氣溶膠罐（第45(b)圖）。藉由比較此二氣 溶膠罐，雖然按壓直到位於初始位置之罐碰到接觸板爲止 之按壓距離不同，自接觸點至釋放位置間的距離基本上相 同（a與b)。這是因爲如以上指出，具有不同長度之閥 桿具有不同按壓距離。由於接觸板14d實質上配設在釋出 位置上方相同按壓距離處，因此，即使氣溶膠罐具有不同 長度之閥桿3b，鎖扣爪14a仍於相同時序鎖緊溝槽13c啣 合。因此，劑量計數器10之更新與排出實質上於此等氣 溶膠罐間的相同時序進行。亦即，即使在閥桿3 b之長度 上有所變動，在兩氣溶膠罐間，藥劑之釋出時序與劑量計 數器之更新時序仍實質上相同，俾病患不會因閥桿長度之 變動而注意到時間滯後。 第四實施例 以下將說明本發明之第四實施例。第四實施例係第四 實施例之修改，茲說明異於第三實施例之元件。首先，如 第46圖所示’於控制蓋20b中，圍繞氣溶膠罐3之外周 面之殼20b2於其下端，沿著周圍具有複數個肋部20r。肋 部2Or徑向延伸以支承氣溶膠罐3。於裝配期間，殼20b2 -27- 200934539 首先裝入殼體2’接者將氣溶膠罐3配置於殼2〇b2內部。 無肋部20r’氣溶膠罐3即可向下移動，使劑量計數器前 進。會有當吸入器掉落’氣溶膠罐3因撞擊力而向下移動 時’劑重計數器則進的情形發生。於本實施例中，肋部 2〇i•之設置使氣溶膠罐3可爲肋部2〇r所支承，俾除非按 壓底板20bl，否則，氣溶膠罐3不會向下移動。這防止含 藥劑氣溶膠釋出或劑量計數器意外前進。 0 以下解釋劑量計數器。於本實施例中，顯示構件13 及控制桿14之構造異於第一實施例者。如於第47及48 圖所示，無凹穴形成於顯示構件13之周圍。替代地，複 數個隆起部13y等角度形成於面對控制桿14之顯示構件 13之周面上。如於第49圖所示，突起14f形成於控制桿 14之中間部分，使突起可與隆起部13y啣合。控制桿14 之止動部14s亦設有突起14 s2，其與隆起部Ι3χ啣合。於 第42圖所示初始狀態中，由於突起14s2之每一者與隆起 ❾ 部13y御合，因此，顯示構件13之旋轉受到限制。若於 此狀態下吸入器掉落，突起14s2與隆起部13y之相互鎖 扣即可能在撞擊下解除。當控制桿1 4沿解除其等之啣合 之方向旋轉時，如於第49圖所示，控制桿14之突起I4f 與顯示構件13之隆起部13y之一啣合，防止顯示構件13 旋轉。因此，本實施例之構造可在不用吸入器時，防止顯 示構件1 3旋轉。 雖然以上說明本發明之實施例’不過’本發明不受以 上討論之實施限制，且可應用於本發明範疇內的許多變化 -28- 200934539 。例如，雖然第三實施例說明氣溶膠罐之凸出與接觸板啣 合，卻是氣溶膠罐之至少一部分須與接觸板啣合，且與接 觸板啣合之部分不特別限制。亦即，與接觸板或控制桿啣 合之氣溶膠罐之部分可爲氣溶膠罐之罐體之端面或周面， 俾接觸板或控制桿可隨著氣溶膠罐移動。 又，氣溶膠罐無須與接觸板啣合，而可與控制桿之任 何部分啣合，只要其能移動控制桿即可。又，控制桿無須 擺動，只要其可於兩位置間移動即可。具體而言，控制桿 不限於一特定構形，只要其能於初始位置與按壓位置之間 即可，俾在從初始位置回到按壓位置時更新劑量計數器’ 並在回到初始位置時，與控制蓋之連結構件一起移動。 又，可設置輔助彈簧，協助氣溶膠罐回到初始位置。 例如，輔助彈簧可盤繞劑量計數器1 〇之軸11 c。如此’ 由於控制桿1 4抵抗輔助彈簧，移至按壓位置’因此’當 氣溶膠罐回到初始位置時，輔助彈簧之力量與氣溶膠罐之 彈簧的力量結合，確保氣溶膠罐一定回到初始位置。此外 ，只要輔助彈簧可協助氣溶膠罐回到原來位置’彈簧即可 安裝於其他位置。例如，彈簧可安裝於殻體2與氣溶膠罐 3之凸出部3c之間，或蓋部之底板2Obi與罐體3a之底部 之間。以上實施例之劑量計數器係正數型，然而，顯示之 數目可重排成倒數型劑量計數器。 又，第三實施例說明當控制蓋自按壓位置回到初始位 置時，操作劑量計數器’惟替代地’可在控制蓋自初始位 置回到按壓位置時，操作劑量計數器。 -29- 200934539 【圖式簡單說明】 第1圖係根據本發明實施之計量吸入器之第一實施例 的立體圖。 第2圖係顯示吸嘴蓋自第1圖之計量吸入器移除之狀 態的立體圖。 第3圖係顯示第1圖之部分切除圖的立體圖。 第4圖係自另一角度顯示第3圖的立體圖。 第5圖係第1圖所示計量吸入器之局部剖視之縱向視 圖。 第6圖係第1圖之計量吸入器之爆炸立體圖。 第7圖係自另一角度顯示第6圖的立體圖。 第8圖係第6圖之局部放大立體圖。 第9圖係第6圖之局部放大立體圖。 第10圖係第7圖之另一局部放大立體圖。 第11圖係第6圖之另一局部放大立體圖。 第12圖係第6圖之又另一局部放大立體圖。 第1 3圖係顯示裝配後之第7圖之控制蓋的局部放大 立體圖。 第14圖係第1圖之計量吸入器之局部放大立體圖。 第15圖係顯示第14圖後之操作狀態之立體圖。 第16圖係顯示一控制桿之另一形式之立體圖，該控 制桿爲根據本發明實施之計量吸入器之構成元件。 第1 7圖係顯示自另一方向所視之第1 6圖之控制桿的 -30- 200934539 立體圖。 第18圖係顯示根據本發明實施之計量吸入器之第二 實施例之局部放大立體圖。 第19圖係顯示第18圖後之操作狀態之立體圖。 第2〇圖係顯示根據本發明實施之計量吸入器之第二 實施例之另一局部放大立體圖。 第21圖係顯示第20圖後之操作狀態之立體圖。 φ 第22圖係顯示根據本發明實施之計量吸入器之第二 實施例之局部放大立體圖。 第23圖係自另—角度顯示第22圖的立體圖。 第24圖係自另一角度顯示吸嘴蓋移除下之第22圖的 立體圖。 第25圖係自另—角度顯示第24圖的立體圖。 第26圖係顯示第25圖後之操作狀態之立體圖。 第27 Η係第22圖中所含鎖緊構件之放大立體圖。 φ 第28圖係第27圖所示鎖緊構件之側視圖。 第29 H係顯示根據本發明實施之計量吸入器之第三 實施例之立體圖。 第30圖係顯示吸嘴蓋自第29圖之計量吸入器移除之 狀態的立體圖。 第31圖係顯示第29圖之局部切除圖的立體圖。 第32圖係自另—角度顯示第31圖的立體圖。 第33圖係第29圖之計量吸入器之局部剖視之縱向視 圖。 -31 - 200934539 第34圖係第29圖之計量吸入器之爆炸立體圖。 第35圖係自另一角度顯示第34圖的立體圖。 第36圖係第34圖之局部放大立體圖。 第37圖係第35圖之局部放大立體圖。 第38圖係第35圖之局部放大立體圖。 第39圖係第34圖之另一局部放大立體圖。 第40圖係第34圖之又另一局部放大立體圖。 第41圖係顯示裝配後之第35圖之控制蓋的放大立體 圖。 第42圖係顯示第29圖之局部切除圖的立體圖。 第43圖係顯示第42圖後之操作狀態之立體圖。 第44圖係氣溶膠罐之解釋圖。 第45圖係顯示氣溶膠罐及接觸板之操作之解釋圖。 第46圖係顯示計量吸入器之另一例子之剖視圖。 第47圖係顯示控制桿之另一例子之立體圖。 第48圖係顯示第47圖所示控制桿之操作之前視圖。 第49圖係顯示第47圖所示之控制槓桿與顯示構件啣 合之解釋圖。 【主要元件符號說明】 1 :計量吸入器 2 :殻體 2f :薄膜部 2 g :通孔 -32- 200934539 3 :氣溶膠罐 3a :罐體 3b :閥桿 4 :吸嘴 5 :吸嘴蓋 5a :突起200934539 IX. DESCRIPTION OF THE INVENTION [Technical field to which the invention pertains] " The invention relates to a dose counter. [Prior Art] As is conventionally known, Metered-dose inhalers are processors used to treat asthma. Dry powder inhalers (DPI) and metered dose inhalers (MDI) _ are known examples of such inhalers. Metered-dose inhalers are also known as push-type metered dose inhalers (PMDI). Generally speaking, The metered dose inhaler contains an aerosol can containing a medicament. Gas-soluble plastic cans generally contain: Tank body Valve stem, Extending from the tank; And the spring, Loaded into the tank. Press the spring to close the valve stem. And when pressed against the spring force of the spring, Release the aerosol. The valve stem is normally held by an aerosol canister attached to the metered dose inhaler. The patient manually pushes the bottom of the can to push the stem into the can. The aerosol containing the drug released from the stem passes through the passage inside the housing. 0 排出 is discharged from the nozzle attached to the housing. Metered dose inhalers equipped with a dose counter to display the number of doses are well known. The dose counter is of an electronic type (for example, Japanese Patent JP-T-2007-513666) or a mechanical type (for example, Japanese Patent JP-T-2003-512265 and US Patent 6, 446, 627). From a cost point of view, Mechanical dose counters are more advantageous than expensive electronic dose counters. Mechanical dose counters are also advantageous in providing disposable metered dose inhalers. Conventional mechanical dose counters include: Indicator panel, With a sign to indicate the number of doses, Rotatable and supported; And a joystick, Use -5- 200934539 to rotate the indicator panel. The lever is forced back to the initial position by elastic means such as a spring. When manually pressing the can body of the aerosol can, The compressive force on the aerosol canister resists the amount of spring pressure of the control rod. Push the lever down ° When the compression force on the aerosol can is released, The lever bounces back to its original position. The lever engages the indicator panel and rotates it by a predetermined angle, At the same time, it is pressed or returned to its original position. that is, In one of the reciprocating movements, The lever rotates the indicator panel, Increase the display by one. however, Further improvements in metered-dose inhalers using the properties of aerosol cans as mechanical dosage meters have been desired. The present invention provides an improved metered dose inhaler that uses the properties of an aerosol can. SUMMARY OF THE INVENTION According to one aspect of the present invention, Providing a metered dose inhaler, include: case; Aerosol can, Contains tanks, a valve stem and a spring that biases the valve stem, Where the valve stem is held in a fixed position inside the housing, And wherein the can body is supported inside the casing, Can be pressed against the spring force of the spring; Dose counter, And a display member rotatably supported inside the housing and a lever pivotably supported inside the housing to rotate the display member; And a control cover, And including at least one structural member rotatably coupled to the control rod and a cover portion covering the can body from a bottom side of the can body Wherein the control cover is driven by the spring of the aerosol can, The lever is swung and retracted. -6- 200934539 With this configuration, The construction of the metered dose inhaler can be simplified by the use of the elasticity of the aerosol canister. ' Metered-dose inhalers may further include means of removal, Used to remove at least the cover of the control cover from the lever. E.g, The removing means may include a fragile portion between the connecting member and the cover portion. The lid portion is cut by the self-joining member. This fragile portion can be a thin wall portion. Take the place, The removal means may comprise a connecting member, It can be bent to cut the connection between the joint member and the lever. The I metered dose inhaler may further comprise: Nozzle, Removably attached to the casing; And a nozzle cover, Covering the nozzle; among them, The nozzle cover includes a projection that operates the removal means. The housing may include removal means, The removing means has a film portion which is burred by the protrusion. also, The metered dose inhaler can be modified such that the housing includes a through hole ’ when the nozzle cover is attached to the nozzle, The protrusion penetrates the housing through the through hole; And the protrusion protrudes into the housing through the through hole, To limit the displacement of the aerosol can. The metered dose inhaler can be changed to this dose counter to further include an auxiliary spring that retracts the control Φ rod. There is no limit to the spring force of the auxiliary spring. E.g, Although the auxiliary spring itself has insufficient elasticity to return the lever, It is strong enough to retract the lever by the spring force of the aerosol can. This spring can be mounted on the second invention of the metered dose inhaler. The metered dose inhaler can be modified to further include: Nozzle, Attached to the housing; Nozzle cover, Covering the nozzle; Locking mechanism 'when the nozzle cover is attached to the nozzle, Limiting the pressing displacement of the aerosol tank; -7- 200934539 Among them, The nozzle cover includes a protrusion, When the nozzle cover is attached to the nozzle, The protrusion can be pierced through the through hole of the nozzle. And wherein the locking mechanism • contains: Tilting the guide, Formed on the lower edge of the cover along the periphery of the cover; And a locking member, contain: Inclined surface, By slidably guiding the inclined guide surface, The inclined surface is movable along the inclined guide surface; As well as the lock, the Ministry, Locking the protrusions together, To prevent the movement of the inclined surface; among them, The locking member supports the inclined guide surface on the inclined surface at a position, Limiting the pressing displacement of the control cover, The locking portion is used to prevent the movement of the inclined surface at the position; And wherein the locking member releases the locking portion from the protrusion, To allow the inclined surface to move, Thereby, it is allowed to control the pressing displacement of the cover. According to a second aspect of the invention, Providing a metered dose inhaler, Including _ aerosol cans, Contains tanks, a valve stem extending from the can body and a spring biasing the valve stem, The valve stem is pressed to release the contents of the aerosol canister t, a holder for holding a valve stem of the aerosol can, To contain the aerosol can; Dose counter, contain: At least one display member, Rotatably supported inside the housing; And the joystick, Supported inside the casing, Rotating the display member; And the control cover' contains: At least one connecting member, Can be combined with the joystick -8 - 200934539 ; And the cover, Covering the can body from the opposite side of the valve stem; The aerosol can is supported in the housing, The can body is pressed against the spring pressure of the spring; The can body of the aerosol canister includes a joint portion that engages the control rod; The lever is movable between the first position and the second position, The first position is a predetermined position between the top end of the valve stem and the engaging portion. And the second position is a pressing position of the control rod engaged with the engaging portion of the can body; The control cover cooperates with the can body, Pressed from the first position, And borrow the spring of the aerosol can, Working with the tank, Returning to the initial position from the pressed position; When the can is pressed with the control cover, The engaging portion of the can body is engaged with the control rod, Moving the lever from the first position to the second position; When returning to the initial position, The connecting member of the control cover moves the control rod from the second position to the first position; And when the lever is moved from the first position to the second position, Or when returning to the first position from the second position, Rotate the display member. With this configuration, The construction of the metered dose inhaler can be simplified by the use of the elasticity of the aerosol canister. The shape of the lever is not limited. E.g, The lever can be provided with a joint with the aerosol can. Aerosol cans are not often in direct contact with the lever. The aerosol canister can pass through other components, Indirectly contact the lever. There is often a change in the length of the stem due to manufacturing tolerances of the aerosol can. E.g , Compared to a shorter stem that requires a shorter pressing distance, Aerosol cans with longer stems have a tendency to require a longer compression distance from the compression point to the release of the contents 200934539. In the present invention, The lever is disposed at a predetermined position between the engaging portion of the can body and the top end of the engaging portion. This is advantageous in the following respects. E.g, With this configuration, Longer stems require a longer pressing distance to allow the can to engage the control rod after pressing. Shorter stems require a shorter pressing distance to allow the can to engage the lever after pressing. By utilizing the relationship between the length of the stem and the required pressing distance for discharge, The discharge contents of the engagement portion of the tank and the control rod can be pressed by the pressing distance regardless of the length of the valve stem. Essentially the same. that is, Even if the stem length changes, The time from the discharge of the contents to the update of the dose counter operated by the joystick can still be substantially the same, Patients with sputum do not have to pay attention to the time lag due to the different stem lengths. The metered dose inhaler can be changed to return the first lever to the first position from the second position. Cooperate with this display member, And rotate this display member. The metered dose inhaler can be changed to this lever containing a stop, This stop locks the display member in the first position, And unwinding the display member in the second position. With this configuration, When the lever is in the initial first position, Locking the rotation of the display component, Preventing accidental rotation of the display member and failure of the dose counter 〇 The lever can have various configurations such as the following. The lever can be configured to include protrusions, The protrusion can engage with the connecting member, And rotatably supported between the first position and the second position; among them, This lever responds to the pressing of the control cover, Swing from the first position to the second position, And among them, The connecting member protrudes from the response control cover, Move together with the swing of the lever without engaging each other; And -10- 200934539 where When the control cover is moved back to the initial position, the connecting structure is engaged with the protrusion. Move the lever from the second position to the first position 〇 again, The metered-dose inhaler can be modified such that the tank body includes a step portion on the surface having the valve stem. And among them, This step portion includes a joint portion. The engaging member is not limited to the step portion. As long as it can be used to tie the lever, Push the lever. I again, The metered dose inhaler can be modified to further include: Nozzle, Removable Ο attached to the housing; among them, The contents of the aerosol canister pass through the nozzle, It is discharged from this housing. By setting the nozzle, The contents discharged from the aerosol can can be directly delivered to the mouth. also, The metered dose inhaler can be modified to further include support means for supporting the can from one side of the valve stem. This prevents when the can is inadvertently pressed during the process of closing the can by the cover portion due to impact force or during assembly of the inhaler. The movement of the can body and the advancement of the counter occur. 有利 advantageous effects by the metered dose inhaler according to the invention, It reduces the compression force of the aerosol canister required for inhalation. [Embodiment] BEST MODE FOR CARRYING OUT THE INVENTION An embodiment of a metered dose inhaler according to the present invention will now be described. -11 - 200934539 First Embodiment Reference will be made to Figs. 1 to 17 below. A first embodiment of a metered dose inhaler implemented in accordance with the present invention is illustrated. As shown in Figure 1, The metered dose inhaler 1 comprises a housing 2 and an aerosol canister 3 housed in the housing 2. As shown in Figure 2, The suction nozzle 4 is attached to the casing 2' and the nozzle cover 5 is detachably provided to the suction nozzle 4. As shown in Figures 3 and 4, Aerosol canister 3 contains: Tank 3a, Roughly _ cylindrical; And the valve stem 3b, Projecting into one end of the can body 3a. By its use, it contains a coil spring (not shown). Pressing the valve stem 3b in the protruding direction, The valve remains closed as shown in Figure 5, The housing 2 includes a cylindrical portion 2a, To contain aerosol cans. As shown in Figure 3, The valve stem 3b faces down, The aerosol can 3 is inserted upside down into the housing 2. Refer to Figure 5, The housing 2 includes a clamping device 2b, Used to clamp the valve stem 3b. The clamping member 2b includes an assembly hole 2bl, It is formed to hermetically assemble the valve stem 3b. The housing 2 is further: Orifice 2c, Connected to the assembly hole g 2bl; And the funnel 2d, Connected to the orifice 2c. Through the funnel 2d, The aerosol released from the valve stem 3b is introduced into the suction nozzle 4. Pressing the can body 3a of the aerosol can 3 against the elastic force of the inner coil spring (not shown), Pushing the valve stem 3b into the aerosol can 3, Open the valve of the valve stem 3b, Thereby allowing the medicament to enter the valve stem 3b, then, The aerosol is released into the nozzle 4 through the orifice 2c and the funnel 2d. Refer to Figures 3 and 4, The dose counter 10 is disposed inside the housing 2. The dose counter 1〇 contains: Support member 11, Fixed to the inner surface of the casing 2; a pair of display members 12 and 13, Rotatablely supported by the support member 11 -12- 200934539; And a control lever 14, Used to rotate the display members 12 and 13. For example, tens of digits of '0 to 1 〇 are printed on the circumferential side of the display member 1 2 at regular intervals. Similarly, the single digits of '0 to 9 are printed on the circumferential side of the display member 13 at regular intervals. therefore, The dose counter 1 〇 can display the number 0 to 109. As shown in Figures 1 and 2, Forming a window 2w on the side of the casing 2, The number on the display members 12 and 13 can be viewed through this window 2w (not shown). As shown in the exploded perspective view in Figures 6 and 7, The display members 12 and 13 are annular rings each having a shaft hole 12a and 13a. Fig. 8 is a partially enlarged perspective view of Fig. 6. Fig. 9 is a partially enlarged perspective view of Fig. 7. Refer to Figure 8, The display member 12 includes a plurality of circumferential locking grooves 12a, It is formed on the side opposite to the display member 13 . As shown in Figure 9, The support member 1 1 includes a pawl 11a that interlocks with the locking groove 12a. The check claw 11a is formed with the locking groove 12a, The check claw 11a prevents the display member 12 from rotating in the direction of the arrow A, but, By being flexible, Allowing when a predetermined torque is applied to the display member 12 in this direction, The display member 12 is rotated in the direction of the arrow B. Fig. 10 is a partially enlarged perspective view of Fig. 7. Fig. 11 is a partially enlarged perspective view of Fig. 6. In Figures 10 and 11, For ease of explanation, The display member 1 2 provided between the support member 1 1 and the display member 13 is omitted. As shown in Figure 10, A plurality of equiangular locking grooves 13b extending in the axial direction are formed on the inner circumferential surface of the shaft hole 13a of the display member 13. The support member 11 includes a check claw lib that is interlocked with the lock groove 13b. The locking groove 13b and the check claw lib are set, The check claw lib prevents the display member 13 -13- 200934539 from rotating in the direction of the arrow A. However, By being flexible, Allowing when a predetermined torque is applied to the display member 13 in this direction, The display member 13 is rotated in the direction of the arrow B. As shown in Figure 10, The display member 13 further includes a plurality of circumferential locking grooves 13c, It is formed on the side thereof facing the display member 12. The control lever 14 is swingably supported by a shaft 11c formed on the support member 11. The top end of the lever 14 is a locking claw 14a that is interlocked with the locking groove 13c (Fig. 11). When swinging in the direction of the arrow B1, The lever 14 swings with the latching pawl 14a that locks with the locking groove 13c. A predetermined torque is applied to the display member 13' and rotated in the direction of the arrow B. When the lever 14 swings in the direction of the arrow A1, The locking claw 14a slides on the inclined surface 13d of the display member 13 (Fig. 1). This is because the check claw nb prevents the display member 13 from rotating in the direction of the arrow A. In one of the strokes of the control lever 14, The display member 13 is rotated by 60°. As shown in Fig. 9, the display member 13 includes a plurality of circumferential locking grooves 12c on one side of its contact with the display member 13. Refer to Figure 11, The display member 13 includes a locking claw i3e that can be locked with the locking groove i2c. As shown in Figure 1, The locking claw 13 has a projection 13f on the side opposite to the display member 12. The protrusion I3f is set to As shown in Fig. 12, which is a partial enlarged view of Fig. 6, the ridge portion 2k formed on the inner side of one portion 2y of the casing 2 slides upward. When the display member 13 rotates to change the display from "9" to "0", the projection 13f of the locking claw 13e slides upward along the ridge 2k, pushing the locking claw 13e toward the locking groove i2c, The locking claw 13e and one of the locking grooves 12c are interlocked with each other. The display member 12 rotates along with the display -14 - 200934539 member 13 When the decimal position 13f on the display member 12 is pushed up to the locking groove 12c, The locking claws I3e are tightly locked to each other by the tight grooves 12c. therefore, The number of displays displayed through the window 2w increases. Referring to a partial enlarged view of Fig. 13, The control cover 20 includes a structural member 20a, Rotatablely coupled to the control rod 14; And the cover portion covers the cover bottom 3a from the bottom side of the cover bottom 3a. The cover portion 20b may include: Base plate 20bl, Can be touched with an aerosol can; And the shell 20b2, Around the perimeter wall of the aerosol can. Shell 20b2 wheel follower 20c. The cam follower 20c engages with a cam groove 2e (Fig. 1) formed on the casing 2. The cam groove 2e extends in the axial direction of the cylindrical portion 2a (Fig. 5), Move back and forth with the guide control cover. Here you need to know, The illustrated cover portion 20b is a two-piece member. The sixth and seventh panels are joined together by an upper portion (bottom plate) 20b1 and a lower portion 20b2. This is for the convenience of manufacturing, And the cover portion 20b can be a single piece type as shown in Fig. 13, The connecting member 20a includes a hook formed at one end of the protruding end, The projection 20d is formed from the casing 20b2 of the cover portion 20b. Referring to Figures 1 and 1 1 , The lever 14 includes a link pin 14c between the locking claws 14a and the hole 14b of the housing shaft 1 lc. As shown in Figure 15 and Figure 15, The lever 14 is engaged by the hook pin 14c of the joint member 20a. It is rotatably coupled to the coupling member 20a. The control lever 14 is swung back and forth due to the vertical reciprocating movement of the cover 20, The member 1 2 is shown. . When the sudden does not work with the lock dosimeter: One after another 20b, The bottom portion includes a convex inner peripheral surface. The housing 2 20 contains a member such as a (shell). From the 20th lower edge extension and used to make the 14th and the connecting rod. Control Rotation -15- 200934539 Note that the coupling member 20a is not limited to the configuration shown in the drawings as long as it is rotatably coupled to the lever 14. E.g, The connecting member can be a connecting rod pin, And the lever can include a pin hole for the link pin to be assembled. As shown in Figure 13, The other connecting member 20a' is formed except for the joint member 20a. The connecting member 20a' is provided to be coupled to the lever 14' having a different swing angle (see Figs. 16 and 17). The lever 14' includes a link pin 14c' and a hole 14b', It is compared to the control lever 14, They are further apart from each other. in this way, If the reciprocating stroke of the control cover 20 is the same, The lever 〇 1 4 ′ swings at a smaller angle than the lever 14 . E.g, By assembling such members to the joint member 20a' or the joint member 20a, A lever 1 4 ' having a smaller angle and a lever 14 having a larger angle are appropriately used for adults and children, respectively. As shown in Figures 10 and 11, The lever 14 includes a stopper 14s, It prevents when the lever 14 does not swing, Display members 12 and 13 are accidentally rotated. The stopper 14s includes a protrusion 14sl, The protrusion 14s1 and the equiangular shape φ are formed on the display member 12, The pocket I2x on the circumference of 13 (see Figure 9) fits. Referring to Figure 13, The control cover 20 includes a fragile portion 20e. It is used to separate the lid portion 20b from the joint member 20a. As shown, The fragile portion 2〇e may be a thin-walled portion formed by a lateral groove which is formed along the width of the projection 20d. The fragile part 20 e is not particularly limited. As long as it is strong enough, it can prevent the lever 11 from being broken during normal operation. E.g, The fragile part 2 〇 e can be formed by reducing the width instead of the thickness shown. As shown in Figure 2, The nozzle cover 5 may have a protrusion 5a, Used to break the brittle -16- 200934539 weak part 20 e. Although it is preferable to use the protrusion 5a, However, it can be broken by other means or methods. Alternatively, The joint member 20a may be provided with a hinge. By this configuration, When the protrusion 5a is pushed inward, The connection between the connecting member and the lever can be cut by bending the connecting member 2〇a inward. E.g, The two 2x and 2y assembled housings 2 shown in Figures 6 and 7 can be constructed to include a removable portion 2y. The user can manually break the fragile portion 20e with a nail. As in the third, As shown in 4 and 7, The casing 2 includes a film portion 2f which can be punctured by the projections 5a. The projection 5a punctures the film portion 2f and collides with a portion slightly below the fragile portion 20e of the control cover 20 to cause breakage at the fragile portion 20e. Preferably, The protrusion 5a has a pushing end, It can easily puncture the film portion 2f. A punched portion may be provided instead of the thin film portion 2f. The housing 2 includes a through hole 2g (Fig. 5). When the nozzle cover 5 is attached to the suction nozzle 4, The protrusion 5a is pierced into the casing 2 through the through hole 2g. As shown in Figure 3, The protrusion 5a penetrates the housing 2 through the through hole 2g. And it abuts against the tongue 20f (Fig. 6) provided on the edge of the casing 20b2 of the control cover 20. This avoids the pressing of the control cover 20 of the aerosol can 3 and the can body 3a to prevent malfunction φ. that is, The nozzle cover 5 is attached to the suction nozzle 4, The aerosol canister 3 cannot be pressed. Please note, Although not shown, the protrusion 5a can be applied to directly abut against the aerosol tank 3. To limit the pressing displacement of the aerosol canister 3. To start the metered dose inhaler, the nozzle cover 5 must be removed from the nozzle 4. Referring to Figures 14 and 15, below, Discuss the operation of the metered dose inhaler. Fig. 14 is a partially cutaway perspective view of the can body 3a before being pressed into the casing 2. 状态 In the state shown in Fig. 14. The stopper 1 4 s and the display member 12 -17- 200934539 13 is engaged to prevent the display member 12, 13 rotation, Thereby preventing malfunctions. For example, 'the stop 14s is suppressed from approaching through the window 2w of the casing 2, Rotating the display member 12, 13 attempts. Fig. 15 is a partially cutaway perspective view showing the state in which the can body 3a has been pressed into the casing 2. With the nozzle cover 5 removed, the user manually presses through the cover portion 2〇b, The can body 3a of the aerosol can 3 is pressed into the casing 2 against the internal coil spring (not shown). This causes the lever 14 coupled to the joint member 20a to be in the position shown in Fig. 14, Swing down to the lower position shown in Figure 12. In the lower position, the locking claw 14a of the lever 14 and the locking groove 13c of the display member 13 (see also Fig. 10) are interlocked with each other. When the can body 3a of the aerosol can 3 is pressed into the casing 2, Under the reaction, the valve stem 3b is pushed into the can body 3a. Allowing the medicament to enter the valve stem 3b, The metered aerosol containing the drug is then released. Containing aerosol from the valve stem 3b, Via port 2c, The funnel 2d and the nozzle 4 (see also Figure 5) release the external 〇 after the release of the aerosol containing the agent, The compressive force applied to the can body 3a through the lid portion 2〇b is released. Under the reaction, The inner coil spring of the aerosol can 3 pushes the control cover 2 back with the can body 3 a '. As the control cover 2 is pushed back, The lever 14 connected to the control cover 20 is swung back to the original position shown in Fig. 14 from the lower position shown in Fig. 15. When the lever 14 is returned to the original position, the locking claw 14a, which is interlocked with one of the locking grooves 13c, rotates the display member 13 by a predetermined angle. This predetermined rotation angle causes the display of the display member 13 to be increased by a desired angle. Please note, As the can 3a returns to the original position of -18-200934539, The valve stem 3 b is returned to its original position ' and the medicament is injected for the next injection. As explained above, In the metered dose inhaler 1 of the first embodiment, the control lever 14 is springed back by the inner coil spring of the aerosol canister 3. Thus the metered dose inhaler 1 can be simple. also, The metered dose inhaler 1 of the first embodiment is composed of ten components other than the aerosol canister 3. All of these components except the aerosol can 3 can be formed by resin forming. When the medicament in the aerosol canister 3 is used up in the metered dose inhaler 1, the fragile portion 20e of the control cover 20 is broken by the projection 5a, The lid portion 20b is separated from the joint member 20a. Since the lid portion 20b simply covers the aerosol can 3 and does not engage with it, therefore, After the lid portion 20b is separated from the joint member 20a, The cover portion 20b can be quickly pulled out from the casing 2. Alternatively, When the joint member 20a has the fragile portion 20e as a fulcrum, Bending around it, When the connection between the lever 14 and the connecting member 20a is broken, The cover portion 20b is quickly removed from the housing 2. Once the cover portion 20b is pulled out, The user can easily take out the aerosol can 3 by simply inserting the stem 3b into the holder H 2b. This allows the metal aerosol can 3 to be easily separated' and disposed of from the ten components formed by other resin molded articles. SECOND EMBODIMENT A second embodiment of a metered dose inhaler according to the present invention will now be described with reference to Fig. 28. The second example is a modification of the first embodiment. therefore, The following description focuses on the changes made, It is not explained in the steps which have been explained in the first embodiment. also, For easy understanding, The same elements in the first and second embodiments are denoted by the same reference numerals. -19- 200934539 As shown in Figures 18 and 19, The second embodiment 100 includes an auxiliary spring 101, The spring force which causes the lever to retract to the primary spring 101 itself is insufficient to make the lever 140 strong by the spring force of the aerosol canister (the retraction of the lever 140 is not shown. Since the aerosol can 3 is prone to manufacturing errors, therefore, The spring 101 compensates for the dimensional change of the aerosol can 3, Or the elastic force of the gas-soluble spring. As shown in the figure, Auxiliary spring spring, Mounted on the shaft 110c of the support member 110, Pressing the lever 140 ^ For example, sometimes, Stem 3b (see Figure 20) 3 The vertical length of the tank is shorter than the designed size. Or the elastic force of the gas-soluble spring is smaller than expected. In such cases, The pressing distance of the released gas 3b will be smaller than expected. therefore, There is less compression deformation in the spring of the spring valve. In this case, the rebound force of the spring of the bomb may be smaller than expected. It is too small to have a rod 140. When returning, The lever 140 and one of the display members 13 13c are interlocked to rotate the display member 13. here, Item 12, The power of 13 must be strong enough to cause the paws Ua (see, Elastic deformation of the pawl 11b (see Fig. 10) or the protrusion 13f (reference). When the rebound of the spring of the spring valve stem 3 b is elastically deformed by the return claw Ha or the check pawl lib, the control is returned. When the aerosol can 3 changes due to design errors, the auxiliary dose counter starts. Auxiliary return, However, it is enough to cause the control to set the auxiliary bullet inside the canister 3. 101 Series Torque Initial position bomb or aerosol can The inside of the canister is inside the stem of the sol stem 3b! Pressure valve stem 3 b Method of retracting control Locking groove Rotating display structure Figure 9) See Figure 10 Power is not enough to make rod 140 without spring 1 0 1 -20- 200934539 Assisting the spring of aerosol can, Make sure the lever 140 is retracted. In other words, The lever 140 is provided to prevent malfunction due to manufacturing errors of the aerosol canister 3. The auxiliary spring 101 is a weak spring ‘ itself cannot retract the lever 14 〇. therefore, The auxiliary spring does not add an extra load that makes it difficult for the user to press the aerosol canister 3. The elasticity can be set to other forces. To compensate for the dimensional error of the aerosol can 3, As shown in Figures 20 and 21, The metered dose inhaler of the second embodiment comprises a control cover 200, It is formed by two components of the upper part and the lower part. These two components are assembled as follows. Please note , The bottom plate 20 Obi of the cover portion 200b of the upper control cover 200, The lower portion is composed of a casing 200b2 of the lid portion 200b of the control cover 200 and a joint member 20a. In the final step of the assembly, When the valve stem 3b is fitted to the press fitting hole 2b1 of the holder 2b (see Fig. 5), The aerosol can 3 is inserted into the lower portion and held therein. Without the force applied to the aerosol can 3, cover, The upper part is placed above the lower part. When the inner bottom surface of the upper portion is in contact with the bottom surface of the aerosol can 3, The upper portion is joined to the lower portion by ultrasonic waves or other joining means. The control cover 200 assembled in this manner can absorb manufacturing errors of the aerosol canister, For example, it is a large or small vertical dimension that is inconsistent with the designed size. These configurations are applicable to the above embodiments. The metered dose inhaler of the second embodiment further includes a locking mechanism, When the nozzle cover is attached to the nozzle, The pressing displacement of the aerosol can 3 is restricted. The locking mechanism will be described below with reference to Figs. 22 to 28. Referring to Figures 22 to 28, The lower edge of the cover portion 200b of the control cover 200 has a plurality of ridges 202, Each of the ridges 202 has an inclined guide surface 20 1 around the periphery of the cover portion 200b. Referring to Figures 22 to 28, Locking mechanism -21 - 200934539 piece 300 is provided to include a plurality of upright portions 302, Each of them has an inclined surface 301 that is slidably guided by the inclined guide 201. The locking member 300 also includes a rotating shaft 303. The rotary shaft 303 is inserted into the shaft hole formed in the support member 110 (see FIGS. 18 and 19). The locking member 300 is rotatably supported to the support member 110. When the control cover 200 is pressed, The inclined guide surface 201 guides the inclined surface 3 0 1, And when the inclined surface 3 0 1 slides along the inclined guide surface, The locking member 300 rotates. As shown in Figure 22, The locking member 3 00 includes a locking projection 304 〇 ' which is interlocked with the projection 5a to prevent the inclined surface 30 1 from moving. As shown in Figure 22, At a position where the locking projection 308 prevents the inclined surface 301 from moving, The inclined surface 301 supports the inclined guide surface 201 to restrict the pressing displacement of the control cover 200. As shown in Figures 24 and 25, When the nozzle cover 5 is removed from the suction nozzle 4 (see Fig. 2), the projection 5a is released from the locking projection 3 04, Allows the movement of the inclined surface 3 0 1 . When a compressive force is applied to the control cover 200, The inclined slope 3 0 1 is displaced along the inclined guide surface 2 0 1 , And the upright φ portion 322 having the inclined surface 310 is moved into the recess 203 immediately adjacent to the ridge 202. Thereby, the pressing displacement of the cover 200 is allowed to be controlled. As mentioned above, In the second embodiment, When the nozzle cover 5 is attached to the suction nozzle 4, The locking mechanism limits the pressing displacement of the aerosol canister 3. As described in the first embodiment, When the nozzle cover 5 is attached, The pressing displacement 5a of the aerosol can 3 is also restricted by the projection 5a which is in contact with the tongue 2〇f (see Fig. 6) to prevent malfunction. Providing the locking member in the second embodiment provides additional safety, In case of failure. Table 2 embodiment -22- 200934539 Reference will be made to Figures 29 to 45 below. A third embodiment of a metered dose inhaler in accordance with the present invention is illustrated. The metered dose inhaler of this embodiment is used to deliver an aerosol medicament directly through the patient's mouth. The appearance is basically as in the first and second embodiments. in particular, As shown in Figure 29, The metered dose inhaler 1 contains: Housing 2 ; Gas-soluble glue tank 3, Included in the housing 2; And a control cover 20, It is fixed to the upper end of the aerosol can 3. also, As shown in Figure 30, The housing 2 includes a suction nozzle 4 and a nozzle cover 5 that is placed in the patient's mouth. The aerosol can 3 is as in the above embodiment. in particular, As shown in Figures 31 and 32, Aerosol canister 3 contains: Generally cylindrical, a can body 3 a containing a medicament, And a cylindrical protrusion 3 C of a small diameter is formed on the lower end surface of the can body 3 a. The tubular valve stem 3b extends downward from the projection (step) 3c. As shown in Figure 33, The housing 2 includes a cylindrical portion 2a. It provides accommodation for the aerosol canister 3. As shown in Figure 31, The aerosol can 3 is facing down with the valve stem 3b, The housing 2 is inserted upside down. As shown in Figure 33, The housing 2 includes a holder 2b for gripping the valve stem 3b. The holder 2b includes an assembly hole 2bl, It is formed to hermetically assemble the valve stem 3b. The housing 2 further comprises: Orifice 2c, Connected to the assembly hole 2bl; And the funnel 2d, Connected to the orifice 2c. Through the funnel 2d, The aerosol released from the stem 3b is introduced into the suction nozzle 4. Pressing the can body 3a of the aerosol can 3 against the elastic force of the inner coil spring (not shown), Pushing the valve stem 3b into the aerosol canister 3, Open the valve of the valve stem 3b. This causes the valve stem 3b to pass through the orifice 2c and the funnel portion 2d, The metered drug-containing aerosol is released into the nozzle 4. -23- 200934539 As shown in Figures 31 and 32, The housing 2 includes a dose counter, It counts the number of inhalers used. The configuration of the dose counter 10 is as in the above embodiment. As seen in a partially enlarged view of Figure 41, The control cover 20 contains: Connecting structural member 20a, Rotatablely coupled to the control rod 14; And a cover portion 20b, The can body 3a is covered from the bottom of the can body 3a. The structure of the joint member 20a is different from that of the above embodiment. The cover portion 20b may include: Base plate 20b 1, Contact with the bottom of the aerosol canister; And the shell 20b2, Around the perimeter wall of the aerosol can. The casing 20b2 includes a cam follower 20c. The cam follower 20c engages with a cam groove 2e (Fig. 29) formed on the inner circumferential surface of the casing 2. The cam groove 2e extends along the cylindrical portion 2a of the casing 2 (Fig. 33). To guide the vertical direction of the control cover 20, Move back and forth. As shown in Figure 41, The joint member 20a is a hook-shaped (J-shaped) member that protrudes from the lower edge of the shell 20b2 of the lid portion 20b. As shown in Figures 38 and 39, The lever 14 includes a link pin (protrusion) 14c between the lock pawl 14a and the hole 14b for accommodating the shaft 1 lc. As shown in Figures 42 and 43, The lever 14 is engaged with the link pin 14c by the joint member 20a. Rotatablely coupled to the vertical movement of the joint member 20a in the joint member 20a, The link pin 14c does not engage with the downwardly moving connecting member 20a, And moving upwards, As explained later, The joint member 20a is engaged with the link pin 14c, And move with it, This causes the lever 14 to swing on the shaft 11c. The horizontally extending contact plate 14d is formed in the vicinity of the link pin 14c of the lever 14 as shown in Figs. That is, between the link pin 14c and the lock -24- 200934539 claw 14a, The crucible is in contact with the projection 3c of the can body 3a. The contact plate 14d initially located between the top end of the stem 3b and the projection 3c is lowered by the depression of the control cap 20 when the can body 3a is pressed. Was pushed out by 3c, The lever 14 is swung on the shaft 11c. As shown in Figures 38 and 39, The lever 14 includes a stopper 14s, It prevents when the lever 14 does not swing, The display members 12 and 13 are unexpectedly rotated. This configuration for preventing the rotation of the display member is the same as that of the first embodiment. I housing 2 also includes a through hole 2g (Fig. 5), Through the through hole 2g, 〇 When the nozzle cover 5 is attached to the suction nozzle 4, The projection 5a is inserted into the housing 2. This configuration is as described in the foregoing embodiment, And no further explanation. The operation of the metered dose inhaler constructed as above will be described below with reference to Figs. 42 and 43. The nozzle cover 5 must be removed from the suction nozzle 4 in order to start the metered dose inhaler. Figure 42 is a partial cutaway perspective view, The initial state before the can body 3a is pressed into the casing 2 is shown. In this state, The stopper 1 4s and the display member 1 2 , : 13 is coupled to prevent the display member 12, 13 failure. Figure 43 is a partial cut of the φ stereogram, The can body 3a pressed into the casing 2 is shown. After the nozzle cover 5 is removed, The patient puts the mouthpiece 4 into the mouth, Or support it in front of your mouth. The patient then manually presses the can body 3a of the aerosol can 3, Via the cover portion 20b, The housing 2 is inserted into the inner coil spring (not shown). This causes the projection 3c of the can body 3a to engage with the contact plate 14d. And when the can body 3a moves downward, Push the contact plate 14d down. result, The lever 14 is swung downward from the position shown in Fig. 42 to the lower position shown in Fig. 43. In this lower position, The locking pawl 14a of the lever 14 is locked to the locking groove 13c of the display member 13 (see also Fig. 38). here, The connecting member 20a connected to the cover -25- 200934539 portion 20b is also moved downward by pressing. However, since the lever 14 swings downward, therefore, Both the connecting member 20a and the link pin 14c of the lever 14 move downward, Not tied together. When the can body 3a of the aerosol can 3 is pressed into the casing 2, The valve stem 3b releases the aerosol containing the medicament. From the valve stem 3b, Containing aerosol from the valve stem 3b, Through the orifice 2c, The funnel 2d and the nozzle 4 (see also Figure 33) release 〇 after releasing the aerosol containing the agent, The compressive force applied to the can body 3a through the lid portion 20b is released. The coil spring inside the aerosol can 3 responds to push the control cover 20 back by the can body 3a. When the control cover 20 is pushed back, The connecting member 20a of the cover portion 2b is engaged with the link pin 14c, And as the link pin 14c moves upward. result, The lever 14 swings from the lower position shown in Fig. 43 to the original position shown in Fig. 42. When the lever 14 returns to its original position, The locking claws 14a that interlock with one of the locking grooves 13c rotate the display member 13 by a predetermined angle. The predetermined rotation angle increases the display of the display member 13 by an angle. Notice, As the can 3 a returns to its original position, The valve stem 3b returns to its original position, And fill the medicine for the next injection. As explained above, In this embodiment, The lever 1 4 is springed back by the inner coil spring of the aerosol canister 3. Thus the construction of the metered dose inhaler can be simple. Please note, The auxiliary spring can be mounted as in the second embodiment. There are often variations in the length of the valve stem due to manufacturing tolerances. E.g, As shown in Figure 44, Compared to an aerosol canister with a short stem that requires a short pressing distance (Fig. 44(b)), Aerosol cans with long stems (Fig. 44(a)) have a tendency to press the distance from the compression point to the longer release point of the content -26-200934539. relatively, In this embodiment, The lever is provided with a contact plate 14d' which is disposed at a predetermined position between the projection 3c of the can body 3a and the tip end of the valve stem 3b. This is advantageous in the following respects. For example, as shown in Figure 45, Consider an aerosol can with a long stem (Fig. 45(a)) and an aerosol can with a short stem (Fig. 45(b)). By comparing this two aerosol cans, Although the pressing distance until the can in the initial position touches the contact plate is different, The distance from the point of contact to the release position is substantially the same (a and b). This is because, as pointed out above, Valve stems with different lengths have different pressing distances. Since the contact plate 14d is substantially disposed at the same pressing distance above the release position, therefore, Even if the aerosol can has valve stems 3b of different lengths, The locking pawl 14a is still engaged by the same timing locking groove 13c. therefore, The renewal and discharge of the dose counter 10 is performed at substantially the same timing between the aerosol canisters. that is, Even if there is a change in the length of the stem 3 b, In between two aerosol cans, The release timing of the medicament is still substantially the same as the update timing of the dose counter. The patient will not notice the time lag due to the change in stem length. Fourth Embodiment A fourth embodiment of the present invention will be described below. The fourth embodiment is a modification of the fourth embodiment, Components that are different from the third embodiment are described. First of all, As shown in Fig. 46, in the control cover 20b, The shell 20b2 surrounding the outer periphery of the aerosol can 3 is at its lower end, There are a plurality of ribs 20r along the circumference. The rib 2Or extends radially to support the aerosol canister 3. During assembly, The case 20b2 -27- 200934539 is first placed in the casing 2'. The aerosol can 3 is placed inside the casing 2〇b2. The ribless portion 20r' aerosol can 3 can be moved downwards. The dose counter is advanced. There is a case where the inhaler falls and the aerosol can 3 moves downward due to the impact force. In this embodiment, The arrangement of the ribs 2〇i• allows the aerosol can 3 to be supported by the ribs 2〇r, 俾 unless you press the bottom plate 20bl, otherwise, The aerosol can 3 does not move downward. This prevents the release of the aerosol containing the medicament or the accidental advancement of the dose counter. 0 The dose counter is explained below. In this embodiment, The configuration of the display member 13 and the control lever 14 is different from that of the first embodiment. As shown in Figures 47 and 48, No recess is formed around the display member 13. Alternatively, A plurality of ridges 13y are formed at equal angles on the circumferential surface of the display member 13 facing the lever 14. As shown in Figure 49, A projection 14f is formed in the middle portion of the lever 14. The protrusion can be engaged with the ridge 13y. The stopper 14s of the lever 14 is also provided with a protrusion 14 s2, It is associated with the ridges. In the initial state shown in Figure 42, Since each of the projections 14s2 is in contact with the ridge portion 13y, therefore, The rotation of the display member 13 is limited. If the inhaler falls in this state, The interlocking of the projections 14s2 and the ridges 13y may be released under impact. When the lever 14 is rotated in the direction in which it is engaged, As shown in Figure 49, The protrusion I4f of the lever 14 is engaged with one of the ridges 13y of the display member 13, The display member 13 is prevented from rotating. therefore, The configuration of this embodiment can be used without an inhaler, The display member 13 is prevented from rotating. Although the embodiments of the present invention have been described above, the invention is not limited by the implementations discussed above. And can be applied to many variations within the scope of the invention -28- 200934539. E.g, Although the third embodiment illustrates that the projection of the aerosol canister is engaged with the contact plate, However, at least a portion of the aerosol canister must be engaged with the contact plate. And the portion that engages with the contact plate is not particularly limited. that is, The portion of the aerosol can that engages the contact plate or the control rod may be the end face or the circumferential surface of the can body of the aerosol can. The contact plate or lever can move with the aerosol canister. also, The aerosol canister does not have to be associated with the contact plate. And can be combined with any part of the joystick, As long as it can move the joystick. also, The lever does not need to swing, As long as it can be moved between the two positions. in particular, The joystick is not limited to a particular configuration, As long as it can be between the initial position and the pressed position, 更新 Updating the dose counter' when returning from the initial position to the pressing position and returning to the initial position, Moves with the connecting member of the control cover. also, An auxiliary spring can be provided, Assist the aerosol canister to return to the initial position. E.g, The auxiliary spring can be wound around the shaft 11 c of the dose counter 1 . So, because the lever 14 resists the auxiliary spring, Move to the pressed position 'so' when the aerosol canister returns to the initial position, The force of the auxiliary spring is combined with the force of the spring of the aerosol can, Make sure the aerosol canister is back to its original position. In addition, As long as the auxiliary spring assists the aerosol can return to its original position, the spring can be installed in other positions. E.g, The spring can be mounted between the housing 2 and the projection 3c of the aerosol can 3, Or between the bottom plate 2Obi of the lid portion and the bottom of the can body 3a. The dose counter of the above embodiment is a positive type, however, The number displayed can be rearranged into a reciprocal dose counter. also, The third embodiment illustrates that when the control cover is returned from the pressed position to the initial position, The operating dose counter 'but alternatively' can be used when the control cover is returned from the initial position to the depressed position, Operate the dose counter. -29- 200934539 BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a perspective view showing a first embodiment of a metered dose inhaler according to the present invention. Figure 2 is a perspective view showing the state in which the nozzle cap is removed from the metered dose inhaler of Figure 1. Fig. 3 is a perspective view showing a partially cutaway view of Fig. 1. Fig. 4 is a perspective view showing Fig. 3 from another angle. Fig. 5 is a longitudinal sectional view, partly in section, of the metered dose inhaler shown in Fig. 1. Figure 6 is an exploded perspective view of the metered dose inhaler of Figure 1. Fig. 7 is a perspective view showing Fig. 6 from another angle. Fig. 8 is a partially enlarged perspective view of Fig. 6. Fig. 9 is a partially enlarged perspective view of Fig. 6. Fig. 10 is another partially enlarged perspective view of Fig. 7. Fig. 11 is another partially enlarged perspective view of Fig. 6. Fig. 12 is still another partially enlarged perspective view of Fig. 6. Fig. 13 is a partially enlarged perspective view showing the control cover of Fig. 7 after assembly. Figure 14 is a partially enlarged perspective view of the metered dose inhaler of Figure 1. Fig. 15 is a perspective view showing the operational state after Fig. 14. Figure 16 is a perspective view showing another form of a lever, The control rod is a constituent element of a metered dose inhaler implemented in accordance with the present invention. Figure 17 shows a perspective view of the -30-200934539 of the joystick of Figure 16 viewed from the other direction. Figure 18 is a partially enlarged perspective view showing a second embodiment of the metered dose inhaler according to the present invention. Fig. 19 is a perspective view showing the operational state after Fig. 18. Fig. 2 is a partially enlarged perspective view showing a second embodiment of the metered dose inhaler according to the present invention. Fig. 21 is a perspective view showing the operational state after Fig. 20. φ Figure 22 is a partially enlarged perspective view showing a second embodiment of the metered dose inhaler according to the present invention. Fig. 23 is a perspective view showing Fig. 22 from another angle. Figure 24 is a perspective view showing the 22nd view of the nozzle cover removed from another angle. Fig. 25 is a perspective view showing Fig. 24 from another angle. Fig. 26 is a perspective view showing the operational state after Fig. 25. Figure 27 is an enlarged perspective view of the locking member included in Fig. 22. φ Fig. 28 is a side view of the locking member shown in Fig. 27. The 29th H series is a perspective view showing a third embodiment of the metered dose inhaler according to the present invention. Figure 30 is a perspective view showing the state in which the nozzle cap is removed from the metered dose inhaler of Figure 29. Fig. 31 is a perspective view showing a partial cutaway view of Fig. 29. Fig. 32 is a perspective view showing Fig. 31 from another angle. Figure 33 is a longitudinal sectional view, partly in section, of the metered dose inhaler of Figure 29. -31 - 200934539 Figure 34 is an exploded perspective view of the metered dose inhaler of Figure 29. Fig. 35 is a perspective view showing Fig. 34 from another angle. Figure 36 is a partially enlarged perspective view of Figure 34. Figure 37 is a partially enlarged perspective view of Figure 35. Figure 38 is a partially enlarged perspective view of Figure 35. Figure 39 is another partially enlarged perspective view of Figure 34. Fig. 40 is still another partially enlarged perspective view of Fig. 34. Fig. 41 is an enlarged perspective view showing the control cover of Fig. 35 after assembly. Fig. 42 is a perspective view showing a partial cutaway view of Fig. 29. Figure 43 is a perspective view showing the operational state after Fig. 42. Figure 44 is an explanatory diagram of an aerosol can. Figure 45 is an explanatory view showing the operation of the aerosol can and the contact plate. Figure 46 is a cross-sectional view showing another example of a metered dose inhaler. Fig. 47 is a perspective view showing another example of the lever. Figure 48 is a front view showing the operation of the lever shown in Figure 47. Fig. 49 is an explanatory view showing the engagement of the control lever shown in Fig. 47 with the display member. [Main component symbol description] 1 : Metered dose inhaler 2 : Housing 2f: Film part 2 g : Through hole -32- 200934539 3 : Aerosol can 3a : Tank 3b: Stem 4 : Nozzle 5 : Nozzle cover 5a: Protrusion
10，100 :劑量計數器 1 2 :顯示構件 1 3 :顯示構件 14，140 :控制桿 20, 200 ：控制蓋 20a :連結構件 20b, 200b :蓋部 1 0 1 :輔助彈簧 300 :鎖緊構件10,100: dose counter 1 2 : display member 1 3 : display member 14, 140: control lever 20, 200: control cover 20a: coupling member 20b, 200b: cover portion 1 0 1 : auxiliary spring 300: locking member