200919486 九、發明說明： 【發明所屬之技術領域】 本發明是有關於-種液體同位素傳送系統 一種可穩定控制液體同位素製作時之壓力， 尤才曰 體同位素製作時具有較佳安全性之功效者。 到液 【先前技術】 目前全世界之正子造影藥物發展快速，而以液體 靶技術所發展出的氟-18氟離子為正子造影之主力放 射造影核種，氟.18氟離伟成為各加速器中心必備之 乾技術，並應用於氟.18a化標幟形成的各種化合物製 作成正子核醫藥物，由於液體乾之傳送系統直接影響 到氟-18氟離子之傳送，能提供穩定度高之液體絲物 質與乾體照射’對於半衰期僅nG分鐘之氟_18放射性 同位素為穩定製造之重要條件，為各正子迴旋加速器 中〜必備之乾技術，具有非常大的市場潛力。 按’一般習用液體同位素於製作時，係由工作人 員於儲存瓶中抽取預定容量之液體，之後再進入照射 靶腔室中，並開啟靶腔室中之液體注入閥及排氣閥將 該液體注入於靶腔令’之後關閉液體注入閥及排氣 閥’且開啟加壓閥將靶腔加壓至所需之壓力，並同時 對靶腔進行質子束照射，藉以使液體形成氟-1 8水之液 體同位素。 200919486 过1用之方式可將液體經由 變形成氟-18水之漭驷n 貝卞末…、射轉 K之液體同位素，但是由於每次進 束照射前，必須由工你 σ 、子 貝由工作人貝將液體注入於靶腔中，因 此，不但所注入之液體量難以控制 = 而π τ从 失肩，且由於腔室中之輻射值極高， =吏：作人員會接受到較高之_ : 貝有安全上之疑慮，再者 t曰 成作人 鉍枷晚士士 r 考以同此1之質子束照射易導 致靶腔中有壓力不穩定 位素之劁作方清^，故，一般習用液體同 '、 式並無法符合實際運用時之所需。 【發明内容】 本發明之主要目的存；& 控制液體同位素;==’可以自動化方式穩定 作時具有較佳安全=力’而達物同位素製 為達上述之目的，太旅 ^ ^ , . A月係一種液體同位素傳送 糸統’包含一至少具有— — τ 力控制機構；-盘第γ門查；及第三調節閥之堡 … 弟—5周即閥連接之送料單元.一办 弟三調節間及送料單元連接之乾腔 二、 側之質子束昭射覃开.，V u t 且π粑腔一 【實施方式】.....料接W存單元。 之『第1及第2圖』所示’係分別為本發明 本㈣方塊示意圖及本發明之整體架構示 如圖所不：本發明係—種 " ,h, ^ ^ 禋履體冋位素傳送系統，J:至 乂係由一壓力控制機構i、— /、 达料早7L 2、一靶腔3、 200919486 一質子束照射單元4以及一儲存單元5所構成，可以 自動化方式穩疋控制液體同位素製作時之壓力，而達 到液體同位素製作時具有較佳安全性之功效。 上这所知1之愿力控制機構1至少包含有一第一調 節閥1 1、及分別與第一調節閥12連接之第二、三 調節閥1 2、1 3 ’其中該第一調節閥^玉係為高壓 凋#閥》亥第一、二調節閥工2、1 3係為低麼調節 閥’而該第-調節閥i 2係連接有供氣瓶工工工，且 該第一、二調節閥1 1、1 2之間係具有-第一開關 部1 1 2，並於該第二調節閥i 2更進一步連接有一 清洗單元6 ’該清洗單元6係透過第二開關部61與 靶腔3連接，另該壓力控制機構工更進—步包含有一 與第三調節閥1 3連接且具有第六開關部丄5 3之壓 力緩衝器1 5，該壓力緩衝器1 5係藉由—第七開關 部1 5 1連接一具有供氣瓶丄4丄之第四調節閥丄 4，且該壓力緩衝器15更連接有，傳輸計" 2，並於該壓力緩衝器ι5鱼第_ 置有一第十二開關部154第一開關部61之間設 該送料單元2係與上述第二調節間工2 且 周節閥1 2與送料單元2之間係具有一第三開 該靶腔3係與上述第三調節閥13及送料單元2 連接，而㈣二調節間工3與乾腔3之間係具有一第 200919486 四及一苐五開關部3 1、32，且該送料單元2與乾 腔3之間係具有一第八及一第九開關部3 3、3 4， 另該乾腔3更配合一第十一開關部3 5連接有一回收 瓶3 6。 該質子束照射單元4係設置於上述靶腔3之一 側。 該儲存單元5係與上述靶腔3連接，而該靶腔3 與儲存單元5之間係具有一第十開關部5 i。如是， 错由上述之結構構成一全新之液體同位素傳送系統。 ^請參閱『第3圖』所示，係本發明之第一使用狀 態示意圖°如圖所示：當本發明進行質子束照射運用 時’係於該送料單元2中注人氧_18水，之後開啟第― =部：…第三開關部21、第八及第九開關部 3?、3 4，並啟動第一及第二調節閥工丨、丄2， 使該供氣觀111提供氣體壓力至第—調節閥丄卜 之後再將氣體壓力經由第二調節閥丄2導入送料單元 2 ’使該送料單^ 2中之氧·18水被導引絲腔3中， 並開啟第五及第十-開關部3 2、3 5，使溢出 :早：4進仃_之質子束照射使靶腔3中之氧 3水轉變成氟-18水；之後再開啟第四及第十開關部 1 5 1 ’並啟動第三調節閥1 3，使第一，節門 1 1將氣體壓力經由第三調㈣1 3導引絲腔^ 200919486 中，讓乾腔3中之氣-18水導入儲存單元5進行儲存。 2閱『第4圖』所示’係本發明之第二使用狀 …圖。如圖所示：當本發 節閥1 1、Ί 2Ί m >併 次弟一為 ^ 進仃貝子束照射運用時，係同 ;=第十二開關部154，使該壓力控制機構k ;力緩衝器15配合壓力傳輸計152不斷即時偵測 第-、二及第三調節間U、"、"之壓力供給 狀况’當壓力過大時’係、開啟第六開關部丄5 3進行 茂壓；而當壓力不足時’則開啟第六開關部…， 使該第四調節閥“藉由供氣概141提供氣體壓 力，並透過壓力緩衝器1 5進行輔助加壓，以使系統 可維持於預定之壓力 ▲請參閱『第5圖』所示，係本發明之第三使用狀 態示意圖。如圖所示：當質子束照射完成後，則可開 啟第-開關部1 1 2、第三開關部2 !、第二開關部 6 1、第九開關部3 4及第十開關部5 1，並於清洗 單元6中注入所需之清潔液或水，並啟動第一及第二 調節閥1 1、1 2 ’使該供氣瓶i !提供氣體愿力 至第一調節閥1 1，之後再將氣體壓力經由第二調節 閥1 2導入清洗單元6，使該清洗單元6中之清潔液 或水被導引至乾腔3中進行清洗，之後再由储存單元 5處將廢水排出不進行儲存。 200919486 综上所述，本發明液體同位素傳送 善習用之種種缺點，可时動化方式= 位素製作時之壓力，而達到液體同位素製作 ，安全性之功效，進而使本發明之産生能更進步又 實用 '更符合使用者之所須’確已符合發明專獅許 之要件，爰依法提出專利申請。 。月 ♦准以上所述者，僅為本發明之較佳實施例而已， 當=能以此限定本發明實施之範圍；故，凡依本發明 申請專利範圍及發明說明書内容所作之簡單的等效變 化與修飾’皆應仍屬本發明專利涵蓋之範圍内。 200919486 【圖式簡單說明】 第1圖，係本發明之基本架構方塊示意圖。 第2圖，係本發明之整體架構示意圖。 第3圖，係本發明之第一使用狀態示意圖。 第4圖，係本發明之第二使用狀態示意圖。 第5圖，係本發明之第二使用狀態示意圖。 【主要元件符號說明】 壓力控制機構1 第一調節閥1 1 供氣瓶111 第一開關部1 1 2 第二調節閥1 2 第三調節閥1 3 第四調節閥1 4 供氣瓶141 壓力緩衝器1 5 第七開關部1 5 1 壓力傳輸計1 5 2 第六開關部1 5 3 第十二開關部1 5 4 12 200919486 送料單元2 第三開關部2 1 乾腔3 第四開關部3 1 第五開關部3 2 第八開關部3 3 第九開關部3 4 第十一開關部3 5 回收瓶3 6 質子束照射單元4 儲存單元5 第十開關部5 1 清洗單元6 第二開關部6 1 13200919486 IX. INSTRUCTIONS: [Technical Field] The present invention relates to a liquid isotope transport system capable of stably controlling the pressure at the time of preparation of a liquid isotope, and is particularly effective in the production of a scorpion isotope. . To the liquid [previous technology] At present, the world's positron angiography drugs are developing rapidly, and the fluorine-fluorine ion developed by the liquid target technology is the main radiography nucleus of the positron angiography, and the fluorine. The dry technology, and applied to the various compounds formed by the fluorine. 18a label, is made into a nucleolar medicinal substance. Since the liquid dry conveying system directly affects the transport of fluorine-18 fluoride ions, it can provide a liquid crystal substance with high stability. With dry body irradiation, the fluorine-18 radioisotope with a half-life of only nG minutes is an important condition for stable manufacturing, and it is a necessary dry technology for each neutron cyclotron, and has a very large market potential. According to the 'general conventional liquid isotope production, the staff extracts a predetermined volume of liquid from the storage bottle, then enters the irradiation target chamber, and opens the liquid injection valve and the exhaust valve in the target chamber to the liquid. Injection into the target chamber to close the liquid injection valve and exhaust valve after 'and open the pressure valve to pressurize the target chamber to the required pressure, and simultaneously irradiate the target chamber with proton beam, so that the liquid forms fluorine-1 8 Liquid isotope of water. 200919486 The method of using 1 can change the liquid to form the fluorine isotope of the fluorine- 18 water, and the liquid isotope of K, but since each time the beam is irradiated, it must be The working person injects the liquid into the target cavity, so that not only the amount of liquid injected is difficult to control = but π τ is lost from the shoulder, and since the radiation value in the chamber is extremely high, =吏: the person will receive higher _ : Bei has security concerns, and then t 曰 成 成 成 铋枷 r r r r r r r 同 同 同 同 同 同 同 同 同 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质 质Therefore, the general use of liquids and ', and can not meet the needs of practical use. SUMMARY OF THE INVENTION The main object of the present invention is to: & control liquid isotope; == 'can be safely stabilized when working with better safety = force ' and the object isotope is made for the above purpose, too travel ^ ^, . A month is a liquid isotope transport system containing a control mechanism with at least - τ force; - the first gamma gate check; and the third regulator valve... Brother - 5 weeks is the valve connection of the feeding unit. The three chambers of the three adjustment chambers and the feeding unit are connected to each other. The proton beam of the side is opened, and the V ut and π chambers are one. [Embodiment] The material is connected to the memory unit. The "1st and 2nd drawings" are respectively a block diagram of the present invention and the overall structure of the present invention is shown as follows: the present invention is a type of ", h, ^ ^ 禋 冋 冋The transfer system, J: to the 乂 is composed of a pressure control mechanism i, — /, a material 7L 2, a target cavity 3, 200919486, a proton beam irradiation unit 4 and a storage unit 5, which can be automated. Controls the pressure during the production of liquid isotope, and achieves better safety when liquid isotope is produced. The force control mechanism 1 of the above-mentioned 1 includes at least a first regulating valve 1 1 and second and third regulating valves 1 2 and 1 3 respectively connected to the first regulating valve 12, wherein the first regulating valve is The jade system is a high-pressure withering valve. The first and second regulating valve workers 2 and 13 are low-regulating valves, and the first-regulating valve i 2 is connected to a gas cylinder worker, and the first The second regulating valve 1 1 and 1 2 have a first switching portion 1 1 2, and the second regulating valve i 2 is further connected with a cleaning unit 6 '. The cleaning unit 6 is transmitted through the second switching portion 61. The target chamber 3 is connected, and the pressure control mechanism further includes a pressure buffer 15 connected to the third regulating valve 13 and having a sixth switching portion 丄53, wherein the pressure buffer 15 is - the seventh switch portion 1 5 1 is connected to a fourth regulating valve 丄4 having a gas cylinder 丄4丄, and the pressure damper 15 is further connected to the transmission meter " 2, and the pressure buffer ι5 _ There is a twelfth switch portion 154. The first switch portion 61 is provided with the feed unit 2 and the second adjustment chamber 2 and the peripheral valve 12 and the feed unit 2 The third opening of the target chamber 3 is connected with the third regulating valve 13 and the feeding unit 2, and the (four) two adjusting chamber 3 and the dry chamber 3 have a 200919486 fourth and a fifth switch portion 3 1, 32, and between the feeding unit 2 and the dry chamber 3 has an eighth and a ninth switch portion 3 3, 3 4, and the dry chamber 3 is further coupled with an eleventh switch portion 35 for recycling Bottle 3 6. The proton beam irradiation unit 4 is disposed on one side of the above-described target chamber 3. The storage unit 5 is connected to the target cavity 3, and the tenth switch portion 5 i is connected between the target cavity 3 and the storage unit 5. If so, the above structure constitutes a new liquid isotope transport system. ^Please refer to FIG. 3, which is a schematic diagram of the first state of use of the present invention. As shown in the figure: when the present invention is used for proton beam irradiation, 'the oxygen is fed to the feeding unit 2, Then, the ―= part:...the third switch part 21, the eighth and ninth switch parts 3?, 3 4 are turned on, and the first and second regulating valve processes, 丄2 are activated, so that the gas supply view 111 supplies the gas After the pressure reaches the first-regulating valve, the gas pressure is introduced into the feeding unit 2 through the second regulating valve '2, so that the oxygen 18 water in the feeding unit 2 is guided into the wire chamber 3, and the fifth and the fifth are opened. Tenth - switch parts 3 2, 3 5, make overflow: early: 4 into the 仃 _ proton beam irradiation to convert the oxygen 3 water in the target cavity 3 into fluorine - 18 water; then turn on the fourth and tenth switch 1 5 1 'and start the third regulating valve 1 3, so that the first, the throttle door 1 1 introduces the gas pressure into the wire cavity ^200919486 through the third (four) 1 3, and the gas 18 water in the dry chamber 3 is introduced into the storage. Unit 5 is stored. 2 "Brief 4" is a second use diagram of the present invention. As shown in the figure: when the first valve 1 1 , Ί 2 Ί m > and the second brother is used to enter the 仃 beam beam irradiation, the same; = the twelfth switch part 154, the pressure control mechanism k; The force buffer 15 cooperates with the pressure transmission meter 152 to continuously detect the pressure supply condition of the first, second and third adjustment chambers U, ", " when the pressure is too large, the system opens the sixth switch unit 丄5 3 The pressure is applied; when the pressure is insufficient, the sixth switch portion is turned on, so that the fourth regulating valve "provides the gas pressure by the air supply 141 and assists the pressure through the pressure buffer 15 to make the system Maintaining the predetermined pressure ▲ Please refer to the figure of Figure 5, which is a schematic diagram of the third state of use of the present invention. As shown in the figure: after the proton beam irradiation is completed, the first switch portion 1 1 can be turned on. The three switch portions 2!, the second switch portion 61, the ninth switch portion 34, and the tenth switch portion 51, and inject the required cleaning liquid or water into the cleaning unit 6, and activate the first and second adjustments. The valve 1 1 , 1 2 ' causes the gas supply bottle i! to supply gas to the first regulating valve 1 1, and then pressurizes the gas The cleaning unit 6 is introduced via the second regulating valve 12, so that the cleaning liquid or water in the cleaning unit 6 is guided into the dry chamber 3 for cleaning, and then the wastewater is discharged from the storage unit 5 without storage. 200919486 As described above, the liquid isotope transmission of the present invention has various disadvantages, and the time can be mobilized = the pressure during the production of the morpheme to achieve the effect of liquid isotope production and safety, thereby making the invention more progressive and practical. 'More in line with the user's requirements' has indeed met the requirements of the invention of the lion, and filed a patent application in accordance with the law. The monthly said that the above is only the preferred embodiment of the present invention, when = can The scope of the present invention is defined by the scope of the invention, and the equivalent equivalents and modifications of the present invention are still within the scope of the invention. 200919486 [Simple description] 1 is a block diagram of the basic architecture of the present invention. Fig. 2 is a schematic view of the overall architecture of the present invention. Fig. 3 is a schematic view showing the first use state of the present invention. 4 is a schematic view of a second state of use of the present invention. Fig. 5 is a schematic view showing a second state of use of the present invention. [Description of main components] Pressure control mechanism 1 First regulating valve 1 1 Gas supply bottle 111 First switch Part 1 1 2 Second regulating valve 1 2 Third regulating valve 1 3 Fourth regulating valve 1 4 Gas supply bottle 141 Pressure buffer 1 5 Seventh switch part 1 5 1 Pressure transfer meter 1 5 2 Sixth switch part 1 5 3 twelfth switch part 1 5 4 12 200919486 feed unit 2 third switch part 2 1 dry cavity 3 fourth switch part 3 1 fifth switch part 3 2 eighth switch part 3 3 ninth switch part 3 4 eleven Switching portion 3 5 recovery bottle 3 6 proton beam irradiation unit 4 storage unit 5 tenth switch portion 5 1 cleaning unit 6 second switch portion 6 1 13