200815818 九、發明說明： 【發明所屬之技術領域】 本發明是關於一種有色隱形眼鏡及其製法，特別是關於利用旋模製法（spin cast)使隱形眼鏡鏡片上形成嵌入之顏料層，以製備有色隱形眼鏡之方法，及依 此製法製成之鏡片。 【先前技術】 隱形眼鏡是-種纽上極為方便之視力駐裝置。尤諸患有近視的人而 言，為增進魏，免除配戴-般眼鏡_煩，常常需要喊隱形眼鏡。200815818 IX. Description of the Invention: [Technical Field] The present invention relates to a colored contact lens and a method of making the same, and more particularly to forming an embedded pigment layer on a contact lens by spin casting to prepare a colored The method of contact lens, and the lens made according to the method. [Prior Art] Contact lenses are extremely convenient visual standing devices. Especially for people with myopia, in order to promote Wei, to avoid wearing glasses--annoying, often need to call contact lenses.
一種可以大量生產隱形眼鏡鏡片的技術’通稱為「spi請st」（旋模成型）， 是由捷克之Cesk—venskaMademieVec^ 1961年所發展出來，並獲得美國第 職⑷號專利權。該技術因多年來不斷改進，而成為業界常用之隱形眼鏡製造 方法。由於使用多元體（polymer)作為鏡片材料，並以大量生產降低成本，使得 「抛棄式」大為流行。時至今日，由於具有色彩的隱形眼鏡的推出，隱形眼 鏡除了矮正功能之外’並且也成為—種裝飾品，或成為服觸一部份。 中華民國專利第79膽06號即是有關一種「具有極自然外觀之有色隱形眼 ^ j ( Colored Contact Lens Having Very Natural Appearance) » β ，並形成不同之圖形，使 隱形眼鏡之鏡片’鏡片之虹膜區上塗有不同顏色之顏料 用者配戴之後，其虹膜可呈現「自然的」色彩。 上述發明試圖研製可以使眼球呈現不同顏色之彩色鏡片。唯其方法均包括製 備一種或_料，再_印在鏡片之凸面上，形成特定之_ (Ρ一。如 顏料t兩種以上，則需依序將娜重疊奸重4印在㈣上。如此形成之有色隱 形眼鏡，具有凸出之練層’麵鑛狀厚度鲜—鋪狀數倍。配戴到使 5 200815818 用者之眼球之後，雖然顏料層厚度極薄（約為〇 〇lm/m到〇 〇8m/m左右），使用 者仍然可能感到異狀。再者，在習用技術中揭示之顏料，為避免對眼睛造成化學 性侵害，-般均使用無機物之礦石（例如ΤΑ)。雖然該礦石讓之粒經一般規 格在5/zm以下，但因眼臉之磨擦，仍可能呈現片狀掉落，而有對眼球產生物理 性傷害之虞。 美國專利第5，116，112號揭示一種彩色鏡片及其製法。該製法之特色乃是在 祕製法巾’未施加鏡單體之前，先據具凹τ表面施以純綱，並使該顏 _ 料硬化成為—雜。接著再加人鏡牌體，而軸鏡#。該發散目的乃在提供 -種在施核過程中不會移位的彩色顏料層。但是該彩色顏料層在鏡片製作完成 後，卻有脫模不全綱題，往往可導致顧層之破片殘留在模具上的問題。 中華民國專利申請絲87丨〗3288號揭示—種隱形眼鏡鏡片之施色方法及其 鏡片。該發明是利用特殊的配方製成彩色隱形眼鏡所使用之顏料組成物 ，以在旋 模製私中％色顏料層不易移位，而在脫模過程中，則可完全雌。但該發明使用 特定之顏料組成，未必可用在各種顏料組成處方。 • 因此，目刖亟需有一種新穎的彩色隱形眼鏡之製法，使其彩色顏料層在鏡片 衣作過中不易易位，且製成後脫膜完全，又不需使用特殊的顏料組成物配方， 而製成彩色隱形眼鏡。 【發明内容】 本％明之目的在提供_種具有新穎之有色隱形眼鏡製法。 本么月之目的也在提供—齡製程巾彩色誠層不祕位，且容易脫模之彩 色隱形眼鏡製法。 柄X月之目的也在提供一種不需使用特殊配方之顏料組成物的有色隱形眼 6 200815818 鏡製法。 本發明之目的也在提供__上述綠製成之有色隱形眼鏡。 依據本發明之隱形目卩過之製造方法，絲在模具之凹下表面先行製作至少一 層保護層，再將顏料塗敷在模具之特定區域，形成一顏料圖樣。其後，於模具上 滴入鏡片材料’以-定速度旋轉該模具，使鏡片形成所欲之曲率表面。將該鏡片 與該顏料圖樣固化’製成有色隱形眼鏡。在本發明的鏡片中，顏料係位於鏡片内 部’因此無逸失於外界嘴眼球造成損傷之虞。於脫模時，更不會導致脫模不全， • _顏料在模具上。本發明並揭示適合上述製程之顏料配方及依該方法製成之鏡 上述及其他本發明之目的及優點，可由以下詳細說明，並參照下列圖式而更 形清楚。 【實施方式】 在習用技術中，隱形眼鏡之鏡片通常是利用親水性高分子聚合物（俗稱水膠 Hydrogel)製成。常見的鏡片材料包括甲基丙烯酸乙酯 _ methac咖bHEMA)。至於適用之顏料是顏料與分散劑，結合劑等之組成物。 經本發明人發現，如果在對有色隱形眼鏡鏡片進行施色前，先在該模具之凹 下表面施加至少-層保護層，則在該保護層上所施加之顏料層，在旋模過程中不 易發生位移。而在完成後之脫膜過程中，也無顏料組成物粘附在模具上，產生殘 留之虞。依本發明方法製成之鏡片因為顏料包覆在鏡片之内，無論是脫模或配戴 時，均不致因顏料脫落而對眼球造成損傷。 以下說明本發明有色隱形眼鏡之製法實施例。 製作本發明之隱形眼鏡鏡片時，首先製造一適用之顏料組成物。本發明之顏 200815818 料組成物可包括分散劑及結合劑，以及一種或數種顏料。 適用在本發明之分散劑（dispersing agent)包括丙烯酸樹脂（acrylicresin) 之單體（monomer)或預聚合體（prep〇lymer)，以及其他適合作為顏料分散劑之 材料，例如··甲基丙烯酸乙酯（HEMA)，曱基丁烯酸乙酯（HPMA)，曱基丙烯 酸甲酯（壓克力單體）（Methyl methacrylate-MMA )、Glyceryl methaeryhte C OMA > 適用在本發明之結合劑（bindingpolymer)包括：壓克力乳化預聚合高分子 或甲基丙烯酸乙酯預聚合物，HEMA，EOEMA ( 2-ethoyethy 1 meth^ykte > MAA (methylacryhe acid甲基丙晞酸）’ IPA (isopropanol異丙醇）等。結合劑之功用 在使鏡片原料配方與顏料配方產生氫鍵或凡得瓦力（VanderWaa丨，sf〇rces)等， 以加強其結合性。 上述成分與顏料組成適用於本發明之顏料組成物。適用在本發明之顏料則包 括：C.I. plgment white 6，C.I. pigment Blue 15:4，C.I. pigment Green 7，C.I· pigment Violet 23 ’ C.I. pigment Yellow 42，C.I. pigment Brown。 在本發明中’顏料組成物可以依不同需要加以組成，並無任何限制。表1顯 示適用於本發明之_組祕之齡及_，可作為參考。其他成份及組成也可 適用在本發明，而得到類似效果。表1另顯示鏡片其他成份之比例。 表1 原料 Crystal Blue Jade Green Violet Cappuccino or Hazel Pearl Gray Rutilel^〇7(cI~^ pigment white 6、 0 〜30% 0-35% 0 〜45% 0 〜20% 0 〜35% Fhtalocyanine Blue (C.L pigment Blue 15:4) 3 〜15% 1〜8% 8 200815818A technique for mass production of contact lens lenses, commonly known as "spi please st" (spinning molding), was developed by Czech Czech Cesk-venskaMademieVec^ in 1961 and obtained the US patent (4). This technology has become a common method of manufacturing contact lenses in the industry due to continuous improvement over the years. "Disposable" is popular because of the use of polymers as lens materials and cost reduction in mass production. Today, due to the introduction of color-sensitive contact lenses, invisible eyeglasses have become a kind of ornament, or become part of the touch, in addition to the short positive function. The Republic of China Patent No. 79 Bile 06 is about a "Colored Lens Having Very Natural Appearance» β and forms a different pattern to make the lens of the contact lens 'the iris of the lens' After wearing the pigments of different colors on the area, the iris can display a "natural" color. The above invention seeks to develop a color lens that allows the eyeball to assume a different color. Only the method includes preparing one kind or material, and then printing on the convex surface of the lens to form a specific one (Ρ一. If the pigment is more than two kinds, it is necessary to sequentially print the negative overlap 4 on (4). The colored contact lens thus formed has a protruding layer of 'small ore-like thickness-sand-like shape. After being worn to make the eyeball of 5 200815818 user, although the thickness of the pigment layer is extremely thin (about 〇〇lm/ From m to 〇〇8m/m), the user may still feel abnormal. Further, in the conventionally disclosed pigments, in order to avoid chemical damage to the eyes, mineral ore (for example, strontium) is generally used. Although the ore allows the grain to be below 5/zm in general, it may still fall off the sheet due to the rubbing of the eye and face, and it may cause physical damage to the eyeball. US Patent No. 5,116,112 A color lens and a method for preparing the same are disclosed. The method is characterized in that before the mirror is applied, the surface of the concave method is applied to the surface of the concave τ, and the surface is hardened into a miscellaneous. Human mirror body, and axis mirror #. The purpose of the divergence is It is a color pigment layer that does not shift during the application of the core. However, after the lens is finished, the color pigment layer has a problem of mold release, which often leads to the problem that the fragments of the film remain on the mold. The Republic of China Patent Application No. 87288, No. 3288 discloses a method for coloring a contact lens and a lens thereof. The invention is a pigment composition used for making a colored contact lens by using a special formula, in a mold making process. The % pigment layer is not easily displaced, but it can be completely female during the demolding process. However, the invention uses a specific pigment composition and may not be used in the formulation of various pigments. • Therefore, it is necessary to have a novel color invisibility. The method of making the glasses makes the color pigment layer difficult to translocate during the lens coating, and the film is completely removed after the preparation, and the color contact lens is not required to be used, thereby forming a colored contact lens. The purpose of % Ming is to provide _ kinds of novel colored contact lens manufacturing methods. The purpose of this month is also to provide - color processing film color layer is not secret, and easy to demolish the color hidden The method of spectacles is also to provide a colored invisible eye 6 which does not require the use of a specially formulated pigment composition. The method of the present invention is also provided. The object of the present invention is also to provide the above-mentioned green colored contact lens. Invented by the invisible manufacturing method, the wire is first formed on the concave surface of the mold to at least one protective layer, and then the pigment is applied to a specific area of the mold to form a pigment pattern. Thereafter, the lens material is dropped onto the mold. 'Rotating the mold at a constant speed to form the desired curvature surface of the lens. Curing the lens with the pigment pattern' to make a colored contact lens. In the lens of the present invention, the pigment is located inside the lens 'so no escape from The outer eyeball causes damage. It does not cause mold release during demolding. • The pigment is on the mold. The present invention also discloses a pigment formulation suitable for the above process and a mirror made according to the method. The objects and advantages of the invention will be apparent from the description and appended claims. [Embodiment] In the conventional technology, the lens of the contact lens is usually made of a hydrophilic high molecular polymer (commonly known as Hydrogel). Common lens materials include ethyl methacrylate _ methac coffee bHEMA). As the applicable pigment, it is a composition of a pigment and a dispersing agent, a binder, and the like. The present inventors have found that if at least a protective layer is applied to the concave surface of the mold prior to color application of the colored contact lens, the pigment layer applied on the protective layer is not easy during the spinning process. A displacement occurred. On the other hand, after the completion of the stripping process, no pigment composition adhered to the mold, resulting in residual defects. The lens produced by the method of the present invention does not cause damage to the eyeball due to the falling off of the pigment, because the pigment is coated in the lens, whether it is demolded or worn. Hereinafter, an embodiment of the method for producing a colored contact lens of the present invention will be described. In making the contact lens of the present invention, a suitable pigment composition is first produced. The pigment of the present invention 200815818 may comprise a dispersant and a binder, and one or more pigments. Suitable dispersing agents for use in the present invention include monomers or pre-polymers of acrylic resin, and other materials suitable as pigment dispersants, such as methacrylic acid B. Ester (HEMA), ethyl decyl crotonate (HPMA), methyl methacrylate (MMA), Glyceryl methaeryhte C OMA > Suitable binding agent for the present invention ) includes: acrylic emulsified prepolymerized polymer or ethyl methacrylate prepolymer, HEMA, EOEMA (2-ethoyethy 1 meth^ykte > MAA (methylacryhe acid methionine)' IPA (isopropanol isopropyl Alcohol), etc. The function of the binder is to make hydrogen bond or VanderWaa®, sf〇rces, etc., to enhance the bondability of the lens material formulation and the pigment formulation. The above components and pigment composition are suitable for use in the present invention. Pigment composition. Pigments suitable for use in the present invention include: CI plgment white 6, CI pigment Blue 15:4, CI pigment Green 7, CI· pigment Violet 23 ' CI pigment Yellow 42 CI pigment Brown. In the present invention, the 'pigment composition can be composed according to different needs without any limitation. Table 1 shows the age and _ of the group which is suitable for use in the present invention, and can be used as a reference. Other ingredients and compositions can also be used. Applicable to the present invention, and similar effects are obtained. Table 1 also shows the ratio of other components of the lens. Table 1 Raw material Crystal Blue Jade Green Violet Cappuccino or Hazel Pearl Gray Rutilel^〇7 (cI~^ pigment white 6, 0 to 30% 0 -35% 0 〜45% 0 〜20% 0 〜35% Fhtalocyanine Blue (CL pigment Blue 15:4) 3 〜15% 1~8% 8 200815818
Phtalocyanine Green (C.I. pigment Green 7) —--—— 15 〜35% Dioxazin Violet (C.I. pigment Violet 23) 3 〜10% --—----__, Iron Oxide (C.I. pigment Yellow 42) 〇〜5% 10 〜30% (C.I. pigment Brown) 4 〜20% 3 〜10% Binding polymer ~~~~—-— 30 〜75% Dispersing agent s___ 5 〜40% 溶劑（IPA) __ 1 〜8% ^ ------------- 、下-兒月本㉟月有色—形眼鏡之製造方法之流程。第1圖為本發明彩色隱形 眼鏡之製讨補雜圖。第2圖表示本發财色隱雜鏡製造方法實施例流程 φ, 示意圖。 如圖所示，於製備本發明之隱形眼鏡鏡片時，首先於（1〇1 )製備一顏料組 成物其-人於（102)在一模具⑴上之凹下表面，施加一或多層保護層⑺。 該保護層⑵之㈣可為任何對人眼無害之高分子化合物、⑪膠、親水性膠、 夕e物#不過在汽際應用上，則以與製備隱开)眼鏡之單體相同之材料，較 為適用，而可使製造成本降低，且管理上較為便利。適用之材料包括：甲基丙婦 酸乙醋（HEMA)，甲基丁婦酸乙_ (HpMA)，甲基丙烯酸甲酉旨（壓克力單體） Φ ( Methyl methacrylate-MMA )、Glyceryl methacrylate ( GMA )等。其形成方法可 包括塗敷，轉印、以旋模製造；或其他可在該模具表面形成薄膜之方法。形成後 可以使其硬化或部份聚合成薄膜，也可不使用硬化或聚合之步驟。接著，於⑽） 利用任何適用之方法，將顏料組成物⑴施於該模具⑴上，該保護膜之裸露 表面，以在模具⑴表面形成顏料圖形。在應用上，可利用移印（padpri嫩） 技術將彩色圖形轉印在模具（1)表面上的保護層⑵上方。所施用之顏色不限 於一種。通常施用之顏色均在三種以下。但超過三種，亦無不可。如超過一種顏 9 200815818 色或形成之圖形需要超過一種模板，可能必須分次印製或施加。第2圖（a)即 顯示施加保護層（2)及顏料組成物（3)後之模具（1)示意圖。 接著’於（104)在模具内倒入隱形眼鏡鏡片材料配方（4)。在應用上，模 具可以聚氣乙烯（PVC)製成。模具（1)之凹面可以球面或非球面設計，但以 其他材料或形狀形成者，亦可適用。眼鏡鏡片材料（4) 一如前述，包括··甲基 丙烯酸乙酯（HEMA)，甲基丁烯酸乙酯（HPMA)，甲基丙烯酸甲酯（壓克力單 體）（Methyl methacrylate-MMA)、Glyceryl methacrylate (GMA)等。但其他材料 g 也可適用。 之後，在（105)以預定之速率，定速率或可變速率旋轉該模具（1)，而使 鏡片原料形成特定之曲率表面。第2圖⑻即顯示一加工中有色隱形眼鏡鏡片 (4)之示意圖。 於(106)開啟上方之紫外燈⑸，照射該鏡片原料⑷及所形成之圖樣⑴ 乂及八下方之保沒層（2)，使其固化。模具⑴旋轉固化時間約2〜⑴分鐘後， 於（107)停止旋轉塑膠模。於⑽）將模具⑴連同其上之鏡片⑷移往退 φ火至進订退火，以消除加工所產生之應力。即可完成有色隱形眼鏡 之製備於應用日守，在（則將完成之未水化鏡片做修邊（e之工作。完 成後於⑽）進行水化程序（脫模）。脫模後之鏡片如第2圖⑷所示。 將70成之1¾片以峽觀察，可以看出其綱圖樣位在鏡片内，表面線條完整 無缺痕。 另將脫模後之㈣置於顯微鏡下觀察，亦發現其表面乾淨，並無顏料或鏡片 之殘片。 200815818 本發明之有色隱形眼鏡因其顏料位在鏡片之内，無凸出之圖樣層，因此使用 時不會因逸落而對眼球造成損傷。 本發明因使用該保護層包覆該顏料圖案，在旋模過程中顏料圖樣不易移位。 因此不必使用特殊之顏料組成物，足崎低製作成本。此外，如使賴片單體作 為保護層之侧，在聚合過射可達職異的聚合效果。 柄明之有色隱形眼鏡鏡#之製造方法不但顧於上述旋模製法，也可適用 於壓模式及其他隱形眼鏡之製法，得到類似之效果。 【圖式簡單說明】 第1圖表示本發明有色隱形眼鏡製造方法實施例流程圖。 第2圖表示本發明有色隱形眼鏡製造方法實施例流程示意圖。 表1顯示適用於本發明之顏料組成物之成分及比例。 【主要元件符號說明】 1 模具 2 保護層 3 顏料組成物 4 眼在兄鏡片材料配方 5 紫外燈Phtalocyanine Green (CI pigment Green 7) ————— 15 to 35% Dioxazin Violet (CI pigment Violet 23) 3 ～10% -------__, Iron Oxide (CI pigment Yellow 42) 〇~5% 10 ~ 30% (CI pigment Brown) 4 ~ 20% 3 ~ 10% Binding polymer ~~~~—-- 30 ~ 75% Dispersing agent s___ 5 ~ 40% Solvent (IPA) __ 1 ~ 8% ^ --- ----------, the next - the month of this month, the process of manufacturing the colored glasses. Fig. 1 is a diagram showing the preparation of the colored contact lenses of the present invention. Fig. 2 is a view showing the flow φ of the embodiment of the present invention. As shown, in the preparation of the contact lens of the present invention, a pigment composition is first prepared at (1〇1), and the human (102) is recessed on a mold (1), and one or more protective layers are applied. (7). (4) of the protective layer (2) may be any polymer compound which is harmless to the human eye, 11 gel, hydrophilic gel, and eve e object. However, in the case of steam application, the same material as the monomer for preparing the spectacles is used. It is more suitable, which can reduce manufacturing costs and is more convenient to manage. Suitable materials include: methyl acetoacetate (HEMA), methyl butyric acid B (HpMA), methyl methacrylate (acrylic monomer) Φ (Methyl methacrylate-MMA), Glyceryl methacrylate (GMA) and so on. The method of forming may include coating, transfer, or spin-molding; or other methods of forming a film on the surface of the mold. After the formation, it may be hardened or partially polymerized into a film, or a step of hardening or polymerization may be omitted. Next, at (10)), the pigment composition (1) is applied to the mold (1) by any suitable method, and the exposed surface of the protective film is used to form a pigment pattern on the surface of the mold (1). In application, the color pattern can be transferred over the protective layer (2) on the surface of the mold (1) by pad printing. The color to be applied is not limited to one. Generally, the colors applied are less than three. But more than three, no matter what. If more than one type of color is required, more than one type of template may be required to be printed or applied in stages. Fig. 2(a) is a view showing the mold (1) after the application of the protective layer (2) and the pigment composition (3). The contact lens material formulation (4) is then poured into the mold at (104). In use, the mold can be made of polyethylene (PVC). The concave surface of the mold (1) may be spherical or aspherical, but may be applied by other materials or shapes. Spectacle lens material (4) As mentioned above, including · ethyl methacrylate (HEMA), ethyl methacrylate (HPMA), methyl methacrylate (acrylic monomer) (Methyl methacrylate-MMA ), Glyceryl methacrylate (GMA), etc. However, other materials g are also applicable. Thereafter, the mold (1) is rotated at a predetermined rate, at a predetermined rate or at a variable rate, to cause the lens material to form a particular curvature surface. Figure 2 (8) shows a schematic view of a colored contact lens (4) in process. The upper ultraviolet lamp (5) is turned on (106), and the lens material (4) and the formed pattern (1) and the underlying layer (2) are irradiated to be cured. After the mold (1) is rotated and solidified for about 2 to 1 minute, the plastic mold is stopped at (107). (10)) Move the mold (1) together with the lens (4) thereon to the φ fire to the finishing annealing to eliminate the stress generated by the processing. The preparation of the colored contact lens can be completed in the application day, and the hydration process (release) of the unhydrated lens (the work of e. As shown in Figure 2 (4). 70% of the 13⁄4 pieces are observed in the gorge, and it can be seen that the outline of the pattern is in the lens, and the surface lines are intact without missing marks. The (4) after demoulding is placed under the microscope and also found. The surface is clean and has no pigment or lens fragments. 200815818 The colored contact lens of the present invention has no protruding pattern layer because of its pigment in the lens, so that it does not cause damage to the eyeball due to falling. The invention coats the pigment pattern by using the protective layer, and the pigment pattern is not easily displaced during the spinning process. Therefore, it is not necessary to use a special pigment composition, and the foot production cost is low. In addition, if the tablet monomer is used as a protective layer On the side, the polymerization effect of the polymerized over-exposure can be used. The manufacturing method of the handle of the colored contact lens is not only the above-mentioned rotary molding method, but also applicable to the pressing mode and other contact lens manufacturing methods. BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a flow chart showing an embodiment of a method for producing a colored contact lens of the present invention. Fig. 2 is a flow chart showing an embodiment of a method for producing a colored contact lens of the present invention. Table 1 shows a pigment suitable for use in the present invention. Composition and proportion of the composition. [Main component symbol description] 1 Mold 2 Protective layer 3 Pigment composition 4 Eye in the lens material formula 5 UV lamp