TW200740796A - Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles - Google Patents

Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles

Info

Publication number
TW200740796A
TW200740796A TW095123570A TW95123570A TW200740796A TW 200740796 A TW200740796 A TW 200740796A TW 095123570 A TW095123570 A TW 095123570A TW 95123570 A TW95123570 A TW 95123570A TW 200740796 A TW200740796 A TW 200740796A
Authority
TW
Taiwan
Prior art keywords
improved process
disubstitutedpropenyl
preparing
substituted heterocycles
phenylalkyl substituted
Prior art date
Application number
TW095123570A
Other languages
Chinese (zh)
Inventor
Jaidev S Goudar
Charles E Hatch Iii
guo-zhi Wang
Craig A Polsz
Russell Patera
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of TW200740796A publication Critical patent/TW200740796A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide

Abstract

An improved process is described for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles. This improved process is focused on steps to produce key intermediates, namely compounds of formula I: where R3, R4, R5 and x are defined herein.
TW095123570A 2005-06-30 2006-06-29 Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles TW200740796A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69582105P 2005-06-30 2005-06-30

Publications (1)

Publication Number Publication Date
TW200740796A true TW200740796A (en) 2007-11-01

Family

ID=37604979

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095123570A TW200740796A (en) 2005-06-30 2006-06-29 Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted heterocycles

Country Status (2)

Country Link
TW (1) TW200740796A (en)
WO (1) WO2007005455A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020219906A1 (en) * 2019-04-25 2020-10-29 Board Of Regents, The University Of Texas System Heterocyclic inhibitors of tyrosine kinase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1597248B1 (en) * 2003-02-14 2007-12-26 Eli Lilly And Company Sulfonamide derivatives as ppar modulators
ATE434612T1 (en) * 2003-04-30 2009-07-15 Bayer Cropscience Ag INSECTICIDES (DIHALOPROPENYL)PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES

Also Published As

Publication number Publication date
WO2007005455A3 (en) 2007-06-14
WO2007005455A2 (en) 2007-01-11

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