TW200736207A - Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin D3 compounds - Google Patents

Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin D3 compounds

Info

Publication number
TW200736207A
TW200736207A TW095110651A TW95110651A TW200736207A TW 200736207 A TW200736207 A TW 200736207A TW 095110651 A TW095110651 A TW 095110651A TW 95110651 A TW95110651 A TW 95110651A TW 200736207 A TW200736207 A TW 200736207A
Authority
TW
Taiwan
Prior art keywords
methyl
compounds
methods
secondary hyperparathyroidism
treating osteoporosis
Prior art date
Application number
TW095110651A
Other languages
English (en)
Inventor
Luciano Adorini
Original Assignee
Bioxell Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioxell Spa filed Critical Bioxell Spa
Publication of TW200736207A publication Critical patent/TW200736207A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW095110651A 2005-03-23 2006-03-28 Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin D3 compounds TW200736207A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66439705P 2005-03-23 2005-03-23
PCT/IB2006/001541 WO2006117684A1 (en) 2005-03-23 2006-03-23 Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin d3 compounds

Publications (1)

Publication Number Publication Date
TW200736207A true TW200736207A (en) 2007-10-01

Family

ID=36793191

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095110651A TW200736207A (en) 2005-03-23 2006-03-28 Methods of treating osteoporosis and secondary hyperparathyroidism using 20-methyl, gemini vitamin D3 compounds

Country Status (6)

Country Link
US (1) US20090298799A1 (zh)
EP (1) EP1898924A1 (zh)
CN (1) CN101198336A (zh)
CA (1) CA2602464A1 (zh)
TW (1) TW200736207A (zh)
WO (1) WO2006117684A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1879596A4 (en) * 2005-03-23 2009-01-21 Bioxell Spa 20 ALKYL, GEMINI VITAMIN D3 COMPOUNDS AND METHOD OF USE THEREOF
US9616109B2 (en) 2014-10-22 2017-04-11 Extend Biosciences, Inc. Insulin vitamin D conjugates
US9585934B2 (en) 2014-10-22 2017-03-07 Extend Biosciences, Inc. Therapeutic vitamin D conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030962A (en) * 1997-04-28 2000-02-29 Synttex (U.S.A.) Inc. Vitamin D3 analogs with bis C-20 side chains
AU762481C (en) * 1998-03-27 2004-08-19 Oregon Health Sciences University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
US6516294B1 (en) * 1999-07-01 2003-02-04 The Regents Of The University Of California Nuclear receptor for 1α,25-dihydroxyvitamin D3 useful for selection of vitamin D3 ligands and a method therefor
JP2006525367A (ja) * 2003-04-30 2006-11-09 ビオクセル エッセ ピ ア ジェミニビタミンｄ３化合物及びその使用方法

Also Published As

Publication number Publication date
CA2602464A1 (en) 2006-11-09
US20090298799A1 (en) 2009-12-03
CN101198336A (zh) 2008-06-11
WO2006117684A1 (en) 2006-11-09
EP1898924A1 (en) 2008-03-19

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