TW200734339A - Forms of dolasetron mesylate and processes for their preparation - Google Patents
Forms of dolasetron mesylate and processes for their preparationInfo
- Publication number
- TW200734339A TW200734339A TW096100622A TW96100622A TW200734339A TW 200734339 A TW200734339 A TW 200734339A TW 096100622 A TW096100622 A TW 096100622A TW 96100622 A TW96100622 A TW 96100622A TW 200734339 A TW200734339 A TW 200734339A
- Authority
- TW
- Taiwan
- Prior art keywords
- processes
- preparation
- forms
- dolasetron mesylate
- dolasetron
- Prior art date
Links
- 229960003218 dolasetron mesylate Drugs 0.000 title abstract 2
- QTFFGPOXNNGTGZ-RCSCTSIBSA-N u3c8e5bwkr Chemical compound O.CS(O)(=O)=O.C1=CC=C2C(C(OC3C[C@@H]4CC5C[C@@H](N4CC5=O)C3)=O)=CNC2=C1 QTFFGPOXNNGTGZ-RCSCTSIBSA-N 0.000 title abstract 2
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75669006P | 2006-01-05 | 2006-01-05 | |
US76368306P | 2006-01-30 | 2006-01-30 | |
US78424806P | 2006-03-20 | 2006-03-20 | |
US80088406P | 2006-05-15 | 2006-05-15 | |
US80284206P | 2006-05-22 | 2006-05-22 | |
US81519906P | 2006-06-19 | 2006-06-19 | |
US81893406P | 2006-07-05 | 2006-07-05 | |
US83351506P | 2006-07-24 | 2006-07-24 | |
US83643206P | 2006-08-07 | 2006-08-07 | |
US83875806P | 2006-08-17 | 2006-08-17 | |
US85288706P | 2006-10-18 | 2006-10-18 | |
US86135406P | 2006-11-27 | 2006-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200734339A true TW200734339A (en) | 2007-09-16 |
Family
ID=37913602
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW096100606A TW200734326A (en) | 2006-01-05 | 2007-01-05 | Crystalline forms of dolasetron base and processes for preparation thereof |
TW096100622A TW200734339A (en) | 2006-01-05 | 2007-01-05 | Forms of dolasetron mesylate and processes for their preparation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW096100606A TW200734326A (en) | 2006-01-05 | 2007-01-05 | Crystalline forms of dolasetron base and processes for preparation thereof |
Country Status (5)
Country | Link |
---|---|
US (4) | US20070203177A1 (zh) |
EP (4) | EP1968588A2 (zh) |
IL (4) | IL190724A0 (zh) |
TW (2) | TW200734326A (zh) |
WO (4) | WO2007081890A2 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009014680A2 (en) * | 2007-07-20 | 2009-01-29 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Polymorphs of dolasetron base and process for preparation thereof |
WO2009014679A1 (en) * | 2007-07-20 | 2009-01-29 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Dolasetron trifluoroacetate, polymorphs of dolasetron trifluoroacetate and process for preparation thereof |
ES2389261T3 (es) * | 2007-11-13 | 2012-10-24 | Inke, S.A. | Compuestos intermedios útiles para preparar dolasetrón |
US9096805B2 (en) * | 2008-06-04 | 2015-08-04 | Nalco Company | Anhydride demulsifier formulations for resolving emulsions of water and oil |
US8969262B2 (en) * | 2008-06-04 | 2015-03-03 | Nalco Company | Utilization of an anhydride as a demulsifier and a solvent for demulsifier formulations |
CN102180878B (zh) * | 2010-07-02 | 2013-06-26 | 成都新恒创药业有限公司 | 一种多拉司琼异构体或其盐及其制备方法和其应用 |
CN103360392A (zh) * | 2013-06-21 | 2013-10-23 | 辽宁海思科制药有限公司 | 一种甲磺酸多拉司琼化合物 |
MA39033A1 (fr) | 2013-11-15 | 2017-11-30 | Akebia Therapeutics Inc | Formes solides d'acide {[5-(3-chlorophényl)-3-hydroxypyridine-2-carbonyl] amino}acétique, compositions et leurs utilisations |
WO2018097150A1 (ja) * | 2016-11-24 | 2018-05-31 | 帝人ファーマ株式会社 | エポキシ化合物の製造方法 |
CN109503580A (zh) * | 2019-01-15 | 2019-03-22 | 南京恩泰医药科技有限公司 | 一种甲磺酸多拉司琼晶型及制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA878096B (en) * | 1986-11-03 | 1988-04-26 | Merrell Dow Pharmaceuticals Inc. | Esters of hexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one and related compounds |
US4906755A (en) * | 1986-11-03 | 1990-03-06 | Merrell Dow Pharmaceuticals Inc. | Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds |
EP0329905A1 (en) * | 1988-02-23 | 1989-08-30 | Merrell Dow Pharmaceuticals Inc. | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for increasing gastric motility |
US5011846A (en) * | 1988-02-23 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof |
EP0330788A1 (en) | 1988-03-01 | 1989-09-06 | Merrell Dow Pharmaceuticals Inc. | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmia |
ZA893008B (en) * | 1988-04-29 | 1989-12-27 | Merrell Dow Pharma | Process for preparing indole-3-carboxylic acid esters of transhexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one |
EP0517984A1 (en) * | 1991-06-11 | 1992-12-16 | Merrell Dow Pharmaceuticals Inc. | Derivatives of amide analogs of certain methano bridged quinolizines |
US5665890A (en) | 1995-03-14 | 1997-09-09 | President And Fellows Of Harvard College | Stereoselective ring opening reactions |
CN100390172C (zh) * | 2004-09-10 | 2008-05-28 | 成都欣捷高新技术开发有限公司 | 一种甲磺酸多拉司琼晶型及其制备方法 |
WO2006056081A1 (de) * | 2004-11-25 | 2006-06-01 | Cilag Ltd. | Verfahren zur herstellung von estern von hexahydro-8-hydroxy-2,6-methano-2h-chinolizin-3(4h)-on |
DE602006003227D1 (de) * | 2005-07-06 | 2008-11-27 | Inke Sa | Verfahren zur gewinnung der pharmazeutisch aktivendavon und verfahren zu deren gewinnung |
WO2007072507A2 (en) | 2005-12-23 | 2007-06-28 | Usv Limited | Polymorphic forms of dolasetron base and processes of preparing dolasetron base, its polymorphic forms and salt thereof |
-
2007
- 2007-01-05 EP EP07709629A patent/EP1968588A2/en not_active Withdrawn
- 2007-01-05 US US11/650,352 patent/US20070203177A1/en not_active Abandoned
- 2007-01-05 EP EP07709611A patent/EP1874767A2/en not_active Withdrawn
- 2007-01-05 TW TW096100606A patent/TW200734326A/zh unknown
- 2007-01-05 TW TW096100622A patent/TW200734339A/zh unknown
- 2007-01-05 US US11/650,294 patent/US7608714B2/en not_active Expired - Fee Related
- 2007-01-05 WO PCT/US2007/000424 patent/WO2007081890A2/en active Application Filing
- 2007-01-05 US US11/650,355 patent/US20070203175A1/en not_active Abandoned
- 2007-01-05 US US11/650,349 patent/US20070203176A1/en not_active Abandoned
- 2007-01-05 WO PCT/US2007/000447 patent/WO2007081907A2/en active Application Filing
- 2007-01-05 EP EP07709613A patent/EP1861397A2/en not_active Withdrawn
- 2007-01-05 WO PCT/US2007/000449 patent/WO2007081909A2/en active Application Filing
- 2007-01-05 EP EP07709631A patent/EP1968978A2/en not_active Withdrawn
- 2007-01-05 WO PCT/US2007/000422 patent/WO2007081889A2/en active Application Filing
-
2008
- 2008-04-08 IL IL190724A patent/IL190724A0/en unknown
- 2008-04-08 IL IL190725A patent/IL190725A0/en unknown
- 2008-04-08 IL IL190723A patent/IL190723A0/en unknown
- 2008-04-16 IL IL190914A patent/IL190914A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007081889A8 (en) | 2008-08-21 |
TW200734326A (en) | 2007-09-16 |
EP1968978A2 (en) | 2008-09-17 |
US7608714B2 (en) | 2009-10-27 |
WO2007081909A2 (en) | 2007-07-19 |
IL190724A0 (en) | 2008-11-03 |
US20070203175A1 (en) | 2007-08-30 |
EP1861397A2 (en) | 2007-12-05 |
WO2007081890A2 (en) | 2007-07-19 |
WO2007081907A3 (en) | 2008-01-17 |
WO2007081890A8 (en) | 2008-08-14 |
US20070203177A1 (en) | 2007-08-30 |
IL190725A0 (en) | 2008-11-03 |
WO2007081889A2 (en) | 2007-07-19 |
WO2007081889A3 (en) | 2007-08-23 |
WO2007081889A9 (en) | 2007-09-20 |
WO2007081890A3 (en) | 2007-09-27 |
EP1874767A2 (en) | 2008-01-09 |
IL190914A0 (en) | 2008-11-03 |
US20070203219A1 (en) | 2007-08-30 |
WO2007081907A2 (en) | 2007-07-19 |
IL190723A0 (en) | 2008-11-03 |
US20070203176A1 (en) | 2007-08-30 |
WO2007081909A3 (en) | 2007-11-22 |
EP1968588A2 (en) | 2008-09-17 |
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