TW200633721A - A pharmaceutical composition for treating constipation - Google Patents

A pharmaceutical composition for treating constipation

Info

Publication number
TW200633721A
TW200633721A TW094144037A TW94144037A TW200633721A TW 200633721 A TW200633721 A TW 200633721A TW 094144037 A TW094144037 A TW 094144037A TW 94144037 A TW94144037 A TW 94144037A TW 200633721 A TW200633721 A TW 200633721A
Authority
TW
Taiwan
Prior art keywords
hydrogen atom
alkyl group
group etc
lower alkyl
compound
Prior art date
Application number
TW094144037A
Other languages
English (en)
Inventor
Tsutomu Suzuki
Takuko Sawada
Yasunobu Ishihara
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of TW200633721A publication Critical patent/TW200633721A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW094144037A 2004-12-14 2005-12-13 A pharmaceutical composition for treating constipation TW200633721A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004360966 2004-12-14
JP2005028927 2005-02-04
JP2005111912 2005-04-08
JP2005296045 2005-10-11

Publications (1)

Publication Number Publication Date
TW200633721A true TW200633721A (en) 2006-10-01

Family

ID=36587835

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094144037A TW200633721A (en) 2004-12-14 2005-12-13 A pharmaceutical composition for treating constipation

Country Status (6)

Country Link
US (1) US20090069363A1 (zh)
EP (1) EP1844792A4 (zh)
JP (1) JPWO2006064780A1 (zh)
CA (1) CA2594987A1 (zh)
TW (1) TW200633721A (zh)
WO (1) WO2006064780A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2625495A1 (en) * 2005-10-11 2007-04-19 Toray Industries, Inc. Therapeutic agent for nausea and/or vomiting
WO2008001859A1 (fr) * 2006-06-30 2008-01-03 School Juridical Person Kitasato Gakuen AGONISTE DES RÉCEPTEURS δ DES OPIOÏDES
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0919893D0 (en) * 2009-11-13 2009-12-30 Biocopea Ltd Drug composition and its use in therapy
CN111905111B (zh) * 2020-09-16 2023-03-31 地奥集团成都药业股份有限公司 一种评价复方谷氨酰胺组方对腹泻型肠易激综合征疗效的方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3247206A (en) * 1962-10-05 1966-04-19 Ciba Geigy Corp Diaza-cycloalkane synthesis
US3253989A (en) * 1963-02-11 1966-05-31 American Cyanamid Co Process for producing anorexia
US3751417A (en) * 1971-08-12 1973-08-07 American Cyanamid Co 1-acyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)indolines
US4082844A (en) * 1976-02-09 1978-04-04 Merck & Co., Inc. 6-chloro-2-(1-piperazinyl)pyrazine
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
US4426383A (en) * 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
DE3364234D1 (en) * 1982-03-02 1986-07-31 Eisai Co Ltd Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
US4619931A (en) * 1983-02-28 1986-10-28 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles
IN164921B (zh) * 1986-07-22 1989-07-08 Hoechst India
EP0370560B1 (en) * 1988-11-24 1994-01-12 Akzo Nobel N.V. Pharmaceutical composition containing 1-[mono- or bis (trifluoromethyl)-2-pyridinyl] piperazines
KR950700065A (ko) * 1992-12-22 1995-01-16 마에다 카쭈노수케 진해제(Antitussive)
EP0809642A1 (en) * 1995-02-15 1997-12-03 PHARMACIA & UPJOHN COMPANY Imidazo 1,2-a]pyridines for the treatment of cns and cardiac diseases
AU712012B2 (en) * 1995-09-26 1999-10-28 Toray Industries, Inc. Indole derivatives and medical application thereof
JP4076234B2 (ja) * 1996-06-28 2008-04-16 明治製菓株式会社 テトラヒドロベンズインドール化合物
IL123986A (en) * 1997-04-24 2011-10-31 Organon Nv Medicinal compounds
US6221868B1 (en) * 1997-06-27 2001-04-24 Nippon Kayaku Kabushiki Kaisha Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives
US6274591B1 (en) * 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
US6465467B1 (en) * 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
AU768310B2 (en) * 1999-07-29 2003-12-04 Eli Lilly And Company Benzofurylpiperazines and benzofurylhomopiperazines: serotonin agonists
EP1225897B1 (en) * 1999-11-01 2004-09-08 RHODES, John Composition for treatment of constipation and irritable bowel syndrome
IL149600A0 (en) * 1999-11-29 2002-11-10 Adolor Corp Novel methods and compositions involving opioids and antagonists thereof
SE9904738D0 (sv) * 1999-12-22 1999-12-22 Astra Pharma Prod Novel compounds
US20030073701A1 (en) * 2001-03-31 2003-04-17 Thompson Lorin A. Succinoylamino heterocycles as inhibitors of a beta protein production
US20040024004A1 (en) * 2001-05-04 2004-02-05 Sherman Barry M. Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists
US6683093B2 (en) * 2000-05-12 2004-01-27 Pharmacia Corporation Aromatic sulfone hydroxamic acids and their use as protease inhibitors
GB0025056D0 (en) * 2000-10-12 2000-11-29 Smithkline Beecham Spa Novel compounds
EP1342717A4 (en) * 2000-11-15 2005-02-16 Banyu Pharma Co Ltd benzimidazole derivatives
GB0030710D0 (en) * 2000-12-15 2001-01-31 Hoffmann La Roche Piperazine derivatives
US7291619B2 (en) * 2001-01-23 2007-11-06 Eli Lilly And Company Melanocortin receptor agonists
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
DE10134721A1 (de) * 2001-07-17 2003-02-06 Bayer Ag Tetrahydrochinoxaline
KR20040038899A (ko) * 2001-09-28 2004-05-08 교와 핫꼬 고교 가부시끼가이샤 수용체 길항제
MXPA04003597A (es) * 2001-10-18 2004-07-30 Nektar Therapeutics Al Corp Conjugados polimericos de antagonistas opiaceos.
JP2005289816A (ja) * 2002-05-14 2005-10-20 Banyu Pharmaceut Co Ltd ベンズイミダゾール誘導体
CA2723494C (en) * 2002-06-19 2013-04-16 Biovitrum Ab (Publ) 2-methyl piperazine derivatives for treatment of serotonin-related disorders
US20060052409A1 (en) * 2002-07-11 2006-03-09 Koji Kawai Therapeutic or preventive agent for nausea/vomiting
CA2529750A1 (en) * 2003-06-20 2005-02-24 Arena Pharmaceuticals, Inc. N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
WO2005103055A1 (en) * 2004-04-21 2005-11-03 Schering Corporation PYRAZOLO-[4,3-e]-1,2,4-TRIAZOLO-[1,5-c]-PYRIMIDINE ADENOSINE A2A RECEPTOR ANTAGONISTS
AU2006228378A1 (en) * 2005-03-31 2006-10-05 Pfizer Products Inc. Cyclopentapyridine and tetrahydroquinoline derivatives

Also Published As

Publication number Publication date
JPWO2006064780A1 (ja) 2008-06-12
EP1844792A1 (en) 2007-10-17
US20090069363A1 (en) 2009-03-12
CA2594987A1 (en) 2006-06-22
WO2006064780A1 (ja) 2006-06-22
EP1844792A4 (en) 2008-05-21

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