TW200621286A - Defective influenza virus particles - Google Patents
Defective influenza virus particlesInfo
- Publication number
- TW200621286A TW200621286A TW094139113A TW94139113A TW200621286A TW 200621286 A TW200621286 A TW 200621286A TW 094139113 A TW094139113 A TW 094139113A TW 94139113 A TW94139113 A TW 94139113A TW 200621286 A TW200621286 A TW 200621286A
- Authority
- TW
- Taiwan
- Prior art keywords
- influenza virus
- provides
- defective
- nucleic acid
- influenza
- Prior art date
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to the field of influenza virus and the vaccination against flu. The invention provides a conditionally defective influenza virus particle having seven different influenza nucleic acid segments. The invention also provides a conditionally defective influenza virus particle lacking an influenza nucleic acid segment selected from the group of segments essentially encoding acidic polymerase (PA), the basic polymerase 1 (PB1) and the basic polymerase 2 (PB2). In particular, the invention provides defective influenza virus particles having seven different influenza nucleic acid segments and lacking an influenza nucleic acid segment essentially encoding acidic polymerase. Furthermore, the invention provides use of a composition comprising a defective influenza virus particle according to the invention for the production of a pharmaceutical composition directed at generating immunological protection against infection of a subject with an influenza virus, and provides a method for generating immunological protection against infection of a subject with an influenza virus comprising providing a subject in need thereof with a composition comprising such defective influenza virus particle.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04105696 | 2004-11-11 | ||
EP05105708 | 2005-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200621286A true TW200621286A (en) | 2006-07-01 |
Family
ID=39869799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094139113A TW200621286A (en) | 2004-11-11 | 2005-11-08 | Defective influenza virus particles |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN102586199A (en) |
BR (1) | BRPI0517742A (en) |
TW (1) | TW200621286A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201310031D0 (en) * | 2013-06-05 | 2013-07-17 | Pirbright Inst The | Cell |
WO2015063085A1 (en) * | 2013-10-28 | 2015-05-07 | Thomas Muster | Novel influenza virus vector for virotherapy |
WO2023138651A1 (en) * | 2022-01-19 | 2023-07-27 | Versitech Limited | Rationally designed single-round infectious virus and methods of use thereof |
-
2005
- 2005-11-08 TW TW094139113A patent/TW200621286A/en unknown
- 2005-11-08 CN CN2012100295719A patent/CN102586199A/en active Pending
- 2005-11-08 BR BRPI0517742-1A patent/BRPI0517742A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BRPI0517742A (en) | 2008-10-21 |
CN102586199A (en) | 2012-07-18 |
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