TW200609229A - The polymorphic form of sodium mycophenolate and its producing method - Google Patents
The polymorphic form of sodium mycophenolate and its producing methodInfo
- Publication number
- TW200609229A TW200609229A TW093127745A TW93127745A TW200609229A TW 200609229 A TW200609229 A TW 200609229A TW 093127745 A TW093127745 A TW 093127745A TW 93127745 A TW93127745 A TW 93127745A TW 200609229 A TW200609229 A TW 200609229A
- Authority
- TW
- Taiwan
- Prior art keywords
- polymorphic form
- type
- sodium mycophenolate
- producing method
- mixture
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
This invention relates to an I type and an II type polymorphic form of sodium mycophenolate and their producing method. In this invention, sodium mycophenolate is reacted with alkali to obtain the mixture of the I type and the II type polymorphic form of sodium mycophenolate. The mixture is heated and circulated in organic solution like alcohol, ester, or ketone for 0.5 to10 hours to obtain the I type polymorphic form. The I type polymorphic form or the mixture of the I type and the II type polymorphic form of sodium mycophenolate is put in an airtight container with a relative humidity of 75 to 96% for about 3 to 28 days to obtain the II type polymorphic form.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW093127745A TW200609229A (en) | 2004-09-14 | 2004-09-14 | The polymorphic form of sodium mycophenolate and its producing method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW093127745A TW200609229A (en) | 2004-09-14 | 2004-09-14 | The polymorphic form of sodium mycophenolate and its producing method |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200609229A true TW200609229A (en) | 2006-03-16 |
Family
ID=57807484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093127745A TW200609229A (en) | 2004-09-14 | 2004-09-14 | The polymorphic form of sodium mycophenolate and its producing method |
Country Status (1)
Country | Link |
---|---|
TW (1) | TW200609229A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110922371A (en) * | 2019-12-27 | 2020-03-27 | 广东蓝宝制药有限公司 | Preparation method of M2 crystal form meclofenol sodium |
-
2004
- 2004-09-14 TW TW093127745A patent/TW200609229A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110922371A (en) * | 2019-12-27 | 2020-03-27 | 广东蓝宝制药有限公司 | Preparation method of M2 crystal form meclofenol sodium |
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