TW200603851A - Microneedle array device and its fabrication method - Google Patents
Microneedle array device and its fabrication methodInfo
- Publication number
- TW200603851A TW200603851A TW093121337A TW93121337A TW200603851A TW 200603851 A TW200603851 A TW 200603851A TW 093121337 A TW093121337 A TW 093121337A TW 93121337 A TW93121337 A TW 93121337A TW 200603851 A TW200603851 A TW 200603851A
- Authority
- TW
- Taiwan
- Prior art keywords
- microneedle
- top portion
- fabrication method
- microneedle array
- array device
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
- B81C1/00111—Tips, pillars, i.e. raised structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/055—Microneedles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/30—Foil or other thin sheet-metal making or treating
- Y10T29/301—Method
- Y10T29/302—Clad or other composite foil or thin metal making
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/30—Foil or other thin sheet-metal making or treating
- Y10T29/301—Method
- Y10T29/303—Method with assembling or disassembling of a pack
- Y10T29/304—Using transitory solid cover material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/30—Foil or other thin sheet-metal making or treating
- Y10T29/301—Method
- Y10T29/308—Using transitory material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/4998—Combined manufacture including applying or shaping of fluent material
- Y10T29/49982—Coating
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW093121337A TWI246929B (en) | 2004-07-16 | 2004-07-16 | Microneedle array device and its fabrication method |
US10/994,105 US20060015061A1 (en) | 2004-07-16 | 2004-11-19 | Microneedle array device and its fabrication method |
US11/754,368 US7712198B2 (en) | 2004-07-16 | 2007-05-29 | Microneedle array device and its fabrication method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW093121337A TWI246929B (en) | 2004-07-16 | 2004-07-16 | Microneedle array device and its fabrication method |
Publications (2)
Publication Number | Publication Date |
---|---|
TWI246929B TWI246929B (en) | 2006-01-11 |
TW200603851A true TW200603851A (en) | 2006-02-01 |
Family
ID=35600412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093121337A TWI246929B (en) | 2004-07-16 | 2004-07-16 | Microneedle array device and its fabrication method |
Country Status (2)
Country | Link |
---|---|
US (2) | US20060015061A1 (zh) |
TW (1) | TWI246929B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108785847A (zh) * | 2013-06-13 | 2018-11-13 | 微德米克斯公司 | 金属微针 |
Families Citing this family (59)
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US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
US20050170670A1 (en) * | 2003-11-17 | 2005-08-04 | King William P. | Patterning of sacrificial materials |
GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
US7132054B1 (en) * | 2004-09-08 | 2006-11-07 | Sandia Corporation | Method to fabricate hollow microneedle arrays |
US7627938B2 (en) * | 2004-10-15 | 2009-12-08 | Board Of Regents, The Univeristy Of Texas System | Tapered hollow metallic microneedle array assembly and method of making and using the same |
KR20060089314A (ko) * | 2005-02-03 | 2006-08-09 | 삼성전자주식회사 | 마이크로 니들 어레이 제조방법 |
US7825037B2 (en) * | 2005-10-17 | 2010-11-02 | Stc.Unm | Fabrication of enclosed nanochannels using silica nanoparticles |
US9156004B2 (en) | 2005-10-17 | 2015-10-13 | Stc.Unm | Fabrication of enclosed nanochannels using silica nanoparticles |
US10060904B1 (en) | 2005-10-17 | 2018-08-28 | Stc.Unm | Fabrication of enclosed nanochannels using silica nanoparticles |
US7588558B2 (en) * | 2005-11-10 | 2009-09-15 | Thera Fuse, Inc. | Laminated sprinkler hypodermic needle |
US7699819B2 (en) | 2006-02-21 | 2010-04-20 | The Hong Kong University Of Science And Technology | Molecular sieve and zeolite microneedles and preparation thereof |
US7951300B2 (en) * | 2006-07-17 | 2011-05-31 | University Of Utah Research Foundation | Water-scale needle array |
US20080138581A1 (en) * | 2006-07-17 | 2008-06-12 | Rajmohan Bhandari | Masking high-aspect aspect ratio structures |
US8865288B2 (en) | 2006-07-17 | 2014-10-21 | University Of Utah Research Foundation | Micro-needle arrays having non-planar tips and methods of manufacture thereof |
EP2062612A4 (en) * | 2006-08-18 | 2010-01-06 | Toppan Printing Co Ltd | MICRO NEEDLE AND MICRO NEEDLE STAMP |
EP2231257A4 (en) | 2007-12-24 | 2013-11-06 | Univ Queensland | APPLICATION METHOD |
CA2749347C (en) | 2008-02-07 | 2018-03-27 | The University Of Queensland | Patch production |
US20090234322A1 (en) * | 2008-03-12 | 2009-09-17 | Ultradent Products, Inc. | Method of dental tissue injection using an array of micro-needles |
US8591481B2 (en) * | 2008-03-21 | 2013-11-26 | Ut-Battelle, Llc | Microfabricated instruments and methods to treat recurrent corneal erosion |
US20090301994A1 (en) * | 2008-05-12 | 2009-12-10 | Rajmohan Bhandari | Methods for Wafer Scale Processing of Needle Array Devices |
CA2760680A1 (en) | 2008-05-23 | 2009-11-26 | The University Of Queensland | Analyte detection by microneedle patch with analyte selective reagents |
US8886279B2 (en) | 2008-06-03 | 2014-11-11 | University Of Utah Research Foundation | High aspect ratio microelectrode arrays enabled to have customizable lengths and methods of making the same |
CN101829396B (zh) * | 2009-03-27 | 2013-01-30 | 清华大学 | 微针阵列芯片及利用其的经皮给药贴剂及其制备方法 |
FI20095433A0 (fi) | 2009-04-20 | 2009-04-20 | Valtion Teknillinen | Mikroneula |
KR101213223B1 (ko) * | 2009-07-07 | 2013-01-09 | 한국전자통신연구원 | 할로우를 가지는 미세 바늘 및 미세 바늘 구조체의 제조 방법 |
US9943673B2 (en) | 2010-07-14 | 2018-04-17 | Vaxxas Pty Limited | Patch applying apparatus |
CN101912663B (zh) * | 2010-08-18 | 2013-09-04 | 清华大学 | 空心微针阵列芯片、经皮给药贴片、器件及制备方法 |
EP2718766A1 (en) * | 2011-06-08 | 2014-04-16 | 3M Innovative Properties Company | Photoresists containing polymer-tethered nanoparticles |
EP2765927B1 (en) | 2011-10-12 | 2021-02-24 | Vaxxas Pty Limited | Delivery device |
WO2013136176A1 (en) | 2012-03-13 | 2013-09-19 | Becton Dickinson France | Injection device having a miniaturized drug delivery portion |
CN104936648A (zh) * | 2013-01-07 | 2015-09-23 | 林治远 | 金属微针 |
US9117765B2 (en) | 2013-11-14 | 2015-08-25 | Taiwan Semiconductor Manufacturing Co., Ltd. | Mechanism for forming semiconductor device structure |
US9933387B1 (en) | 2014-09-07 | 2018-04-03 | Biolinq, Inc. | Miniaturized sub-nanoampere sensitivity low-noise potentiostat system |
EP3253440B1 (en) | 2015-02-02 | 2022-12-21 | Vaxxas Pty Limited | Microprojection array applicator |
US11103259B2 (en) | 2015-09-18 | 2021-08-31 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
US20170095417A1 (en) * | 2015-10-06 | 2017-04-06 | Yoshikazu Tobinaga | Percutaneous Implement and Method for Manufacturing |
JP6732373B2 (ja) * | 2016-03-31 | 2020-07-29 | 花王株式会社 | 微細中空突起具の製造方法、及び微細中空突起具 |
US10092207B1 (en) | 2016-05-15 | 2018-10-09 | Biolinq, Inc. | Tissue-penetrating electrochemical sensor featuring a co-electrodeposited thin film comprised of polymer and bio-recognition element |
DK3606760T3 (da) | 2017-03-31 | 2023-11-06 | Vaxxas Pty Ltd | Indretning og fremgangsmåde til belægning af overflader |
US11045142B1 (en) | 2017-04-29 | 2021-06-29 | Biolinq, Inc. | Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry |
WO2018227246A1 (en) | 2017-06-13 | 2018-12-20 | Vaxxas Pty Limited | Quality control of substrate coatings |
EP3661587A4 (en) | 2017-08-04 | 2021-06-09 | Vaxxas Pty Limited | COMPACT HIGH MECHANICAL ENERGY STORAGE AND LOW RELEASE FORCE ACTUATOR FOR MICROPROJECTION NETWORK (PRM) PATCH DELIVERY |
WO2019111959A1 (ja) * | 2017-12-05 | 2019-06-13 | 古河電気工業株式会社 | 機能性部材及びその製造方法 |
USD875254S1 (en) | 2018-06-08 | 2020-02-11 | Biolinq, Inc. | Intradermal biosensor |
IT201800006526A1 (it) * | 2018-06-20 | 2019-12-20 | Microago cavo per la somministrazione transdermica di molecole attive e/o per il campionamento di fluidi biologici e metodo di fabbricazione di tale microago cavo | |
JP6985310B2 (ja) * | 2019-01-31 | 2021-12-22 | 富士フイルム株式会社 | マイクロニードルアレイの製造方法 |
CN110482481B (zh) * | 2019-07-08 | 2023-04-04 | 南京航空航天大学 | 一种末端膨大微结构阵列仿生黏附材料的制备方法 |
US11291818B2 (en) * | 2020-04-01 | 2022-04-05 | Nanopass Technologies Ltd. | Microneedle structure for intradermal injection |
CN111621816B (zh) * | 2020-05-27 | 2022-03-29 | 大连理工大学 | 一种超高深宽比金属微柱阵列的制作方法 |
EP4048152B1 (en) | 2020-07-29 | 2023-12-20 | Biolinq Incorporated | Continuous analyte monitoring system with microneedle array |
KR102297883B1 (ko) * | 2021-02-17 | 2021-09-03 | 주식회사 지엘캄퍼니 | 마이크로 니들조립체 |
USD988160S1 (en) | 2021-03-16 | 2023-06-06 | Biolinq Incorporated | Wearable dermal sensor |
US11857344B2 (en) | 2021-05-08 | 2024-01-02 | Biolinq Incorporated | Fault detection for microneedle array based continuous analyte monitoring device |
CN113209466A (zh) * | 2021-05-11 | 2021-08-06 | 苏州揽芯微纳科技有限公司 | 一种单晶硅空心微针结构及其制作方法 |
US11717660B2 (en) * | 2021-07-29 | 2023-08-08 | Nanopass Technologies Ltd. | Silicon microneedle structure and production method |
USD1013544S1 (en) | 2022-04-29 | 2024-02-06 | Biolinq Incorporated | Wearable sensor |
USD996999S1 (en) | 2021-11-16 | 2023-08-29 | Biolinq Incorporated | Wearable sensor |
CN114935595B (zh) * | 2022-04-15 | 2024-02-06 | 北京大学 | 一种微针生物传感器的制造方法 |
USD1012744S1 (en) | 2022-05-16 | 2024-01-30 | Biolinq Incorporated | Wearable sensor with illuminated display |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
US6256533B1 (en) * | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
US6551849B1 (en) * | 1999-11-02 | 2003-04-22 | Christopher J. Kenney | Method for fabricating arrays of micro-needles |
WO2001049346A2 (en) * | 1999-12-30 | 2001-07-12 | Redeon, Inc. | Stacked microneedle systems |
IL134997A0 (en) * | 2000-03-09 | 2001-05-20 | Yehoshua Yeshurun | Health care system based on micro device |
US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
US7131987B2 (en) * | 2000-10-16 | 2006-11-07 | Corium International, Inc. | Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation |
US9302903B2 (en) * | 2000-12-14 | 2016-04-05 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
US6663820B2 (en) * | 2001-03-14 | 2003-12-16 | The Procter & Gamble Company | Method of manufacturing microneedle structures using soft lithography and photolithography |
IL152271A (en) * | 2002-10-13 | 2006-04-10 | Meir Hefetz | Structures of micro needles and manufacturing methods |
US20050011858A1 (en) * | 2003-07-16 | 2005-01-20 | Industrial Technology Research Institute | Method for fabricating a hollow micro-needle array |
US8353861B2 (en) * | 2003-09-18 | 2013-01-15 | Texmac, Inc. | Applicator for applying functional substances into human skin |
US7627938B2 (en) * | 2004-10-15 | 2009-12-08 | Board Of Regents, The Univeristy Of Texas System | Tapered hollow metallic microneedle array assembly and method of making and using the same |
-
2004
- 2004-07-16 TW TW093121337A patent/TWI246929B/zh not_active IP Right Cessation
- 2004-11-19 US US10/994,105 patent/US20060015061A1/en not_active Abandoned
-
2007
- 2007-05-29 US US11/754,368 patent/US7712198B2/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108785847A (zh) * | 2013-06-13 | 2018-11-13 | 微德米克斯公司 | 金属微针 |
CN108785847B (zh) * | 2013-06-13 | 2020-10-20 | 微德米克斯公司 | 金属微针 |
Also Published As
Publication number | Publication date |
---|---|
US20060015061A1 (en) | 2006-01-19 |
US20070233016A1 (en) | 2007-10-04 |
TWI246929B (en) | 2006-01-11 |
US7712198B2 (en) | 2010-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |