TW200538139A - Chinese herbal medicine combo for treatment of derma fungus infection or burn - Google Patents

Chinese herbal medicine combo for treatment of derma fungus infection or burn Download PDF

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TW200538139A
TW200538139A TW93113892A TW93113892A TW200538139A TW 200538139 A TW200538139 A TW 200538139A TW 93113892 A TW93113892 A TW 93113892A TW 93113892 A TW93113892 A TW 93113892A TW 200538139 A TW200538139 A TW 200538139A
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alcohol
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TW93113892A
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shi-cai Zhang
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shi-cai Zhang
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Abstract

This invention concerns a Chinese herbal medicine combo for treatment of derma fungus infection or burn, comprising of borneol, menthol, and summer cypress pure extracts; wherein the weight ratio of borneol and menthol is 1:3. This invention also concerns preparing for Chinese herbal medicine combo for treatment of derma fungus infection or burn, which includes (a) preparing a liquid mixture of borneol and menthol, with weight ratio of 1:3; (b) soaking summer cypress into medicinal alcohol for a period of time and then filtering off the residue; and (c) mixing the solution of (a) and (b) in any ratio.

Description

200538139 玖、發明說明: 【發明所屬之技術領域】 本發明相關於一種用於、、人 裡用於冶療皮膚黴菌感染或 中藥組成物及其製法。 ί1易之 【先前技術】 於曰常生活中充斥著各式各樣的黴菌,黴 的環境’過分乾燥的環境並不適合黴菌生存,因此只要^、 膚-直保持乾爽的環境狀況下,便不容易引來黴菌而得到 皮膚病’尤其是因為腳的部位因為穿著襪子和鞋子,因此 容易流汗而過於潮濕造成足癬(俗稱香港腳),引起足癖的 是一種白癖菌’白癖菌是-種真菌,它寄生在皮膚的角質 内’以角蛋白為營養源,香港腳在潮濕的台灣是非常常見 的皮f病,有許多人終其—生為它所惱,因此非常需要適 合的藥劑治療。 另外在曰吊生活中’燒褒傷的意外事件層出不窮,據 衛生署的統計在台灣地區每年至少有二千多例因嚴重烫傷 的意外事件而必須住院治療,而其中又以幼兒的燒水烫傷 占其中的大數,常會引起敗血症、肺衰竭、休克而死亡, 如何及時做好正確的急救處理,是減少降低傷害程度的最 佳準則*大豕耳热能詳的燒烫傷急救五步驟為··「沖、脫 /包蓋送」,然而這五步驟最後常會形成疤痕而需植 皮二而市售的燒烫傷藥品絕大多數是軟膏的型態,以軟膏 形怨塗抹於受傷的皮膚表層常會阻礙其散熱功能,也阻礙 200538139 了皮膚與空氣中氧氣的接觸,進而妨礙皮膚受傷部位的復 原速度’因&如何能避免形成症痕為非常重要的—點。 【發明内容】 於本發明之-較佳具體事實中,本發明提供一種用於 治療皮膚黴菌感染之中藥組成物,其係包含冰片、薄荷腦 和地膚子之醇萃取物’其中冰片與薄荷腦之重量比為u Ο 較佳地’本發明所述之中藥組成物中,該地膚子之醇 萃取物為乙醇萃取物。 另一方面,於本發明之-較佳具體事實中,本發明提 供-種用於治療燒㈣之中藥組成物,其係包含冰片、薄 荷腦和地膚子之醇萃取物,纟中冰片與薄荷腦之重量比為 1:3。 較佳地,本發明所述之中藥組成物中,該地膚子之醇 萃取物為乙醇萃取物。 另-方面,於本發明之—較佳具體事實中,本發明提 供-種製備用於治療皮膚黴菌感染之中藥組成物的方法, 包括: ⑷將冰片和薄荷腦以重量比為1:3的比例混合成液體 ’ ⑻將地膚子浸》藥用酒精内後經過一段時間將地膚子 渣濾淨;及 (c)將(a)與(b)之溶液以任意比例混合而得。 200538139 較佳地’本發明所述 # /u、卜 # 气方法中,該(b)步驟係將地膚子 浸於樂用酒精内兩週後將地膚子誠淨。 于 較佳地,本發明所述 _ μ <方法中,泫(b)步驟之地膚子盥 藥用酒精之比例為i錢:〇1 一 至1 A升,更佳地,該(b)步驟 之地膚子與藥用酒精之比你 比例為1錢:0.5公升。 較佳地’本發明所述 _ ^ χ ^ Κ方法中,該(c)步驟係將⑷盥 (b)之溶液以1:ι〇至ι〇·ι ” 主w.1的比例混合,更佳地,該(c)步驟 係將(a)與(b)之溶液以1:1的比例混合。 另方Φ力本發明之一較佳具體事冑中本發明提 供一種製備用於治療燒烫傷之中藥組成物的方法,包括: •⑷將冰片和薄荷腦以重量比為1:3的比例混合成液體 (b) 將地膚子浸於藥用酒精内後經過一段時間將地 渣濾淨;及 (c) 將(a)與(b)之溶液以任意比例混合而得。 較佳地’本發明所述之方法中,該⑼步驟係將地膚子 浸於藥用酒精内兩週後將地膚子渣濾淨。 較佳地,本發明所述之方法中,該(b)步驟之地膚子與 藥用酒精之比例為i錢^至i公升,更佳地,該⑻步驟 之地膚子與藥用酒精之比例為丨錢:〇·5公升。 軏佳地本發明所述之方法中,該(C)步驟係將(a)與 (b)之溶液以1:10至1〇:1的比例混合,更佳地,該步驟 係將(a)與(b)之溶液以ι:1的比例混合。 於本發明之一較佳具體事實中,該冰片與薄荷腦以 200538139 1 : 3的比例混合可混合成液體,如果此比例不正確將無法 形成液體,此乃發明人經過不斷的嘗試與實驗結果所得。 由於一般人上班時間雙腳僅能在鞋内戳動,欲脫下鞋 子截動則總是不適當也不雅觀,因此於本發明之一較佳具 體事實中,本發明之中藥組成物可喷灑於腳趾間,初覺刺 痛感,但約三分鐘後即有涼爽感覺,一日喷上數次,連續 喷數日,可痊癒不再復發,此乃因薄荷主含揮發油,體外 試驗薄荷煎劑對特定病毒有抑制作用,包括:金黃色葡萄 球菌、白色葡萄球菌、炭疽桿菌、白喉桿菌、傷寒桿菌、鲁 綠膿桿菌、大腸桿菌等;而薄荷油外用能刺激神經末梢的 感受器而產生冰冷感覺,並反射性地造成深部組織血管的 變化而具有消炎、止痛、止疼的作用;而薄荷腦能選擇性 地刺激人體皮膚或黏膜的冷覺感受器,產生冷覺反射和冷 感,引起皮膚黏膜血管收縮(實際上皮膚溫度仍保持正常 )’對深部組織的血管也可引起收縮而產生治療作用,外 :可以止痛、止疼、蚊蟲叮咬等;而地膚子水浸劑對許多 常見治病性皮膚真菌均有不同程度的抑制作用;而冰片又鲁 名梅片、龍腦香’在本草備藥的主治功能記載有目赤膚翳 、痘陷、三蟲五痣等,從這些主治來看均是些發炎疾病, 與現在的皮膚黴菌感染所造成的發炎均相吻合。 於本發明之一較佳具體事實中,本發明之中藥組成物 ^於治療燒烫傷’在處理烫傷時先以沖(只需用清水沖 :次’不需持續數分鐘)、脫的步驟處理,再用本發明所 提供之中藥組成物溶液於第一時間噴於燙傷部位上(15分 7 200538139 鐘内喷數次)’初時感覺皮膚散熱’ $而使皮膚受傷組織 加速復原,只要保持皮膚散熱功能,受傷的部位就不會起 水泡’當然癒後也不會有疤痕的問題存在,完全去除了後 績繁雜的問題;市售的燒燙傷藥品絕大多數是軟膏的型雜 ,以軟膏形態塗抹於受傷的皮膚表層常會阻礙其散熱功能 ,也阻礙了皮膚與空氣中氧氣的接觸,進而妨礙皮膚受傷 部位的復原速度,而於本發明之一較佳具體事實中,本發 明所提供之中藥組成物是以液體形態喷於皮膚表面,因此 不會影響皮膚的復原,故而可防止症痕的產生。 另外於本發明之一具體事實中,本發明之中藥組成物 經由試驗檢測具有治療皮膚黴菌感染的效果,其係於數名 受測體受黴菌感染的區域,每天喷灑本發明之中藥組成物 數次並持續數週後,受測體皮膚不再出現紅疹、水泡以及 脫皮的現象,故由結果顯示,喷灑本發明中藥組成物有治 療皮膚黴菌感染的效果。 另於本發明之一具體事實中,本發明之中藥組成物經 由動物試驗以及臨床試驗測試具有治療燒烫傷的效果。於 動物試驗中,係測試受燒燙傷傷害的受測體,其中一組喷 灑本發明之中藥組成物,而另一組噴灑一般常溫水,結果 顯示’有喷灑本發明中藥組成物的一組其恢復的時間相較 於另一組縮短了將近一倍的時間,而一般燒燙傷的黃金救 援時間大約在三分鐘内,經由燙傷時迅速喷灑本發明之中 藥組成物後,其治療時間縮短了近一倍。另外於臨床試驗 中,亦證明於受燒烫傷時迅速喷灑本發明之中藥組成物, 200538139 並有利於皮膚修復功能,不致留 明之中藥組成物具有治療燒燙傷 可縮短受傷恢復的時間, 下疤痕,由此可證明本發 的效果。 【實施方式】 實例 下列貫施例用於示範說明本發明。這些實施例不以任 何方式意欲限制本發明之範圍,但用於指示如何實施本發 明的材料及方法。 實施例1:製備中藥組成物 與薄 酒精 兩種 首先取冰片1兩、薄荷腦3兩混合待成液體(冰片 荷腦的比例為1:3混合),另外取地膚子1錢浸於藥用 〇·5公升内經過兩週後將地膚子渣濾淨,之後將上迷 溶液以1:1比例混合而成。 實施例2:試驗中藥組成物於治療皮膚黴菌感染之 2.1.方法 測試四位患有足癖之患者。 將實施例1所製備之組成物喷灑於測試體患處,相R 一段時間後,再次進行噴灑動作,每天噴灑數次,連續數 週持續喷灑組成物於測試體患處。 2.2.結果 患者患處剛喷灑組成物時’感覺疼痛’約30秒後, 疼痛感轉為舒適的刺激感並覺得涼爽,經由一週後,足癬 200538139 &成之水泡、脫皮以及紅疹現象消失,並呈現正常的膚 或呈乾燥樣的粉紅色,數週後,不再出現;1癖症狀。200538139 (1) Description of the invention: [Technical field to which the invention belongs] The present invention relates to a composition for the treatment of skin fungal infections or traditional Chinese medicine and its preparation method. ί1 Yizhi [Previous Technology] Yu Yue's daily life is full of all kinds of molds. The moldy environment is too dry for mold survival. Therefore, as long as the skin is kept in a dry environment, it is not necessary. It is easy to attract mold and get skin diseases. Especially because the feet are wearing socks and shoes, so they sweat easily and become too wet, which causes athlete's foot (commonly known as Hong Kong feet). What causes foot addiction is a white addiction fungus. -A kind of fungus, which parasitizes in the keratin of the skin. 'With keratin as the nutrient source, Hong Kong feet are a very common skin disease in wet Taiwan. Many people end up being born annoyed by it, so they need a suitable one. Medicament treatment. In addition, in the life of hanging, there are endless incidents of burns. According to the statistics of the Department of Health, at least 2,000 cases of severe burns must be hospitalized every year in Taiwan, and among them, children's boiled water Scalds account for most of them, and they often cause sepsis, lung failure, and death from shock. How to do the right first-aid treatment in time is the best guideline to reduce the degree of injury. Five steps for first-aid burns In order to "rush, take off / cover", however, these five steps will often form scars and require skin grafting. Most of the commercially available burns and scald drugs are in the form of ointments, which are applied to the injured in the form of ointment. The surface layer of the skin often hinders its heat dissipation function, and it also hinders the contact of the skin with oxygen in the air, which in turn hinders the speed of healing of the injured part of the skin. It is very important-how to avoid the formation of scars. [Summary of the Invention] In a preferred specific fact of the present invention, the present invention provides a Chinese medicinal composition for treating skin fungal infections, which is an alcohol extract containing borneol, menthol and scutella, wherein borneol and mint The weight ratio of the brain is u 0. Preferably, in the traditional Chinese medicine composition according to the present invention, the alcohol extract of the phylloxera is ethanol extract. On the other hand, in a preferred specific fact of the present invention, the present invention provides a Chinese medicinal composition for treating burnt tincture, which is an alcohol extract containing borneol, menthol and scutella, The weight ratio of menthol is 1: 3. Preferably, in the traditional Chinese medicine composition of the present invention, the alcohol extract of the phloem is ethanol extract. On the other hand, in a preferred specific fact of the present invention, the present invention provides a method for preparing a traditional Chinese medicine composition for treating skin fungal infections, comprising: ⑷ borneol and menthol in a weight ratio of 1: 3 Proportionally mixed into a liquid ⑻ immersed in the medicament alcohol, and then filtered the diarrhea residue after a period of time; and (c) mixing the solutions of (a) and (b) in any ratio. 200538139 Preferably, in the # / u, Bu # gas method described in the present invention, the step (b) is to soak the ground skin in the alcohol for two weeks to clean the ground skin. Preferably, in the method described in the present invention, the proportion of the medicinal alcohol used in step (b) is i: 0.001 to 1 A liter, and more preferably, (b) The ratio of step to skin and medicinal alcohol is 1 dollar: 0.5 liter. Preferably, in the method _ ^ χ ^ κ described in the present invention, the step (c) is to mix the solution of the toilet bowl (b) at a ratio of 1: ιο to ι 〇 · ι, and more Preferably, the step (c) is to mix the solutions of (a) and (b) in a ratio of 1: 1. In addition, in one of the preferred embodiments of the present invention, the present invention provides a preparation for treating burns. A method for scalding a traditional Chinese medicine composition, including: ⑷ mixing borneol and menthol into a liquid in a ratio of 1: 3 by weight (b) immersing ground spores in medicinal alcohol and slag after a period of time Filtering; and (c) mixing the solutions of (a) and (b) in an arbitrary ratio. Preferably, in the method of the present invention, the step of immersing the phloem in the medicinal alcohol After two weeks, the ground dregs are filtered. Preferably, in the method of the present invention, the ratio of the ground dross to the medicinal alcohol in step (b) is from i to ^ to i liter, more preferably, In this step, the ratio of ground skin to medicinal alcohol is 丨 money: 0.5 liter. In the method according to the present invention, the step (C) is the step (a) and (b) of the solution 1:10 to 10: 1 ratio Mixing, more preferably, this step is to mix the solutions of (a) and (b) in a ratio of ι: 1. In a preferred specific fact of the invention, the borneol and menthol are in a ratio of 200538139 1: 3 Mixing can be mixed into a liquid. If this ratio is not correct, it will not be able to form a liquid. This is the result of continuous experiments and experiments by the inventor. Since most people can only poke their feet in shoes during work hours, if they want to take off the shoes, they will move. It is always inappropriate and unsightly. Therefore, in one of the preferred specific facts of the present invention, the Chinese medicinal composition of the present invention can be sprayed between the toes, and the tingling sensation is initially felt, but there is a cool feeling after about three minutes. Sprayed several times a day, sprayed for several consecutive days, can be cured without recurrence. This is because peppermint contains volatile oil. Peppermint decoction in vitro has inhibitory effects on specific viruses, including: Staphylococcus aureus, Staphylococcus aureus, and Bacillus anthracis , Diphtheria, Typhoid, Pseudomonas aeruginosa, E. coli, etc .; external use of peppermint oil can stimulate the receptors of nerve endings to produce a cold feeling, and reflectively cause changes in deep tissue blood vessels. It has anti-inflammatory, analgesic, and analgesic effects; while menthol can selectively stimulate cold sensory receptors on the human skin or mucous membranes, generating cold sensory reflexes and cold sensations, causing the skin and mucosal blood vessels to contract (in fact, the skin temperature remains normal) 'It can also cause contraction of the blood vessels in deep tissues and produce a therapeutic effect. In addition: it can relieve pain, pain, mosquito bites, etc .; and the scutellar water extract has different degrees of inhibition on many common curative skin fungi; And borneol is also named plum tablet and borneol. The main functions of herbal medicine preparation include red skin rash, acne, three insects and five moles. From these points of view, they are all inflammatory diseases, and the current skin mold Inflammation caused by infections are all consistent. In a preferred specific fact of the present invention, the Chinese medicinal composition of the present invention is used in the treatment of burns and scalds. (It does not need to last for several minutes), take off the steps, and then use the traditional Chinese medicine composition solution provided by the present invention to spray it on the scalded area at the first time (15 minutes 7 200538139 several times in the clock). Skin heat dissipation speeds up the recovery of injured skin tissues. As long as the skin heat dissipation function is maintained, there will be no blisters in the injured area. Of course, there will be no scar problem after healing, and the problem of complicated performance will be completely removed; Most of the burns and scald medicines are ointment-type impurities. Applying the ointment to the surface of injured skin often hinders its heat dissipation function, and also prevents the skin from contacting with oxygen in the air, which in turn hinders the speed of recovery of the injured part of the skin. In a preferred specific fact of the present invention, the traditional Chinese medicine composition provided by the present invention is sprayed on the surface of the skin in a liquid form, so it does not affect the restoration of the skin, and thus can prevent the occurrence of scars. In addition, in a specific fact of the present invention, the Chinese medicinal composition of the present invention has the effect of curing skin fungal infections through testing. It is applied to the areas where several test subjects are infected by molds, and the Chinese medicinal composition of the present invention is sprayed daily. After several times and continued for several weeks, the subject's skin no longer appeared rash, blisters, and peeling, so the results show that spraying the traditional Chinese medicine composition has the effect of treating skin fungal infection. In a specific fact of the present invention, the Chinese medicinal composition of the present invention has an effect of treating burns and scald through animal tests and clinical tests. In animal tests, subjects tested for burns and burns were tested. One group was sprayed with the Chinese medicinal composition of the present invention, and the other group was sprayed with normal temperature water. The results showed that 'there was a spray of the Chinese medicinal composition of the present invention. Compared with the other group, the recovery time of the group was shortened by nearly one time. The golden rescue time of general burns and scalds is about three minutes. After the traditional Chinese medicine composition of the present invention is rapidly sprayed during scalds, the treatment time is shortened. Shortened nearly twice. In addition, in clinical trials, it has also been proved that the traditional Chinese medicine composition of the present invention is quickly sprayed during a burn and scald, 200538139, and is conducive to the skin repair function. Scars can prove the effect of this hair. [Embodiment] Examples The following examples are provided to illustrate the present invention. These examples are not intended to limit the scope of the invention in any way, but are used to indicate how to implement the materials and methods of the invention. Example 1: Preparation of Chinese medicinal composition and thin alcohol. First, take two of borneol and two of menthol to prepare a liquid. After two weeks in 0.5 liters, the ground dregs were filtered, and the solution was mixed at a ratio of 1: 1. Example 2: Test of Traditional Chinese Medicine Composition for the Treatment of Skin Fungal Infections 2.1. Methods Four patients with foot problems were tested. The composition prepared in Example 1 was sprayed on the affected part of the test body. After a period of time R, the spraying operation was performed again, spraying several times a day, and the composition was continuously sprayed on the affected part of the test body for several weeks. 2.2. Results About 30 seconds after the composition was sprayed on the affected area of the patient, the pain turned into a comfortable stimulus and felt cool. After one week, tinea pedis 200538139 & blistering, peeling, and rash phenomenon Disappears and presents normal skin or a pinkish appearance. After a few weeks, it no longer appears;

以實驗組與對照組作比較,實驗組以實施例 :組成物噴於受熱水烫傷的白鼠身上,而對照組以常心 嘴於受熱水t傷的白鼠身上,以兩組作比較。 3 · 1 · 1.材料 實驗用溫度計 滴管二支 、(別於身上約二公分見方範圍去毛) 噴霧型容器二個壯成 個裝常溫水) (個襞實施例1所製備之組成物, 燒杯一個 酒精燈一個 計時器一個 3 · 1 · 2 ·方法及結果 ^_ -------~~Ί 0’〇〇,, 實驗組狀態 以滴管取燒杯内彿水(沸 點96。〇滴五滴於白鼠身 ------ 以滴管取燒杯内沸水(沸 --- 點96。〇滴五滴於白鼠身 jijL毛部分 ---——--- 200538139 0,30,, --- 將裝於噴霧型容器内的 常溫水喷於白鼠患部 將裝於噴霧型容 組成物噴於白鼠患部, 前足拭眼 2,00,, 6鼠患部發紅並產生血 絲,有滲出液 白乳患部發紅,無炎出 液,頻以前足拭眼,並 生、部 第二次將組成物噴於白 鼠患處,白鼠以前足軾 身貼抵患 白鼠患部發紅 7’00" 第一次將常溫水噴於白 鼠患處 9,00,, 白鼠患部發紅並產逢^ ^ 絲 12,00,, 第三次將常溫水嘴於白 鼠患處 第二次將組成物噴於白 鼠患處,白鼠以前足拭 A,並轉_身貼抵患_ 白鼠患部發紅,呈粉紅 色 15’00,, 白鼠患部發紅並羞4 絲 19,00,, —--_ 白鼠患部發紅而血轉、、封 漸消去 白鼠患部發紅漸漸消去 23f00M ____ 白鼠患部發紅而血絲漸 漸消去 -—___ 白鼠患部無恙 30,00,, — 白鼠患部顏色粉紅 白鼠患部無恙 45,00,, -- 白鼠患部無恙 白鼠患部無恙 由結果玎知’ 貫驗組白 氣於3 〇秒時噴第一次組成物 200538139 後,頻以雙足拭眼,並轉身貼抵患部,此可說明組成物具 有刺激性。 而於2分鐘時,實驗組白鼠患部並無滲出液,而對照 組白鼠患部有血絲且有渗出液,此可說明組成物對皮膚受 烫傷時有即時的復原效果,即時發揮散熱功能;且燒烫傷 的黃金救援時間只在三分鐘之内,若超過三分鐘,其治療 時間將會延長。 於15分鐘時,實驗組白鼠患部已呈粉紅現象,而對 照組白鼠患部仍有血絲,此點更可說明黃金救援時間的重春 要性,以及組成物對燒燙傷的療效。 經由使用組成物治療燙傷的白鼠,其復原時間將會縮 短,而沒有使用組成物治療的白鼠,其復原時間將近延長 一倍。 3·2·臨床試驗 實驗組:受滾烫開水燙傷腿部之男性 對照組:受滾烫開水燙傷腿部之男性 實驗男性於受燙傷時,立即喷灑實施例1所製備之中 藥組成物’經由喷灑3至4分鐘後,其患部有發紅現象, 再喷灑第二次該中藥組成物,經5分鐘後,雖患部仍有發 紅現象’但皮膚外觀無其他反應,再喷灑第三次該中藥組 成物’患者皮膚外觀無恙,再次喷灑10分鐘後,患者並 無出現水泡且發紅現象消去。 對照組男性於受烫傷時,並未喷灑實施例1所製備之 12 200538139 中藥組成物, 癒並留下疤痕 經由傳统 方法治療後 將近一個月的時間疾 根據本發明可作之X π a 者而顧狹π合# 及變化對於熟習該項技術 、 離本發明的範圍與精神。雖然本發明 已敘述特定的較佳具體事眚 體事實必頊瞭解的是本發明不應被 不當地限制於該等特定呈體塞眘u ,、腹爭貫上。事實上,在實施本發 明之已述模式方面,對於孰習該瑁 …為这項技術者而言顯而易知之 不同修正亦被涵蓋於下列申請專利範圍之内The experimental group is compared with the control group. The experimental group is based on an example: the composition is sprayed on the hot-burned rats, while the control group uses the Changxin mouth on the hot-water injured rats, and the two groups are compared. . 3 · 1 · 1. Two thermometer droppers for material experiment, (different from about two centimeters square hair removal in the body) two spray-type containers to form a room temperature water) (a composition prepared in Example 1) , A beaker, an alcohol lamp, a timer, 3 · 1 · 2 · methods and results ^ _ ------- ~~ Ί 0'〇〇, the state of the experimental group with a dropper to take the water in the beaker (boiling point 96 〇5 drops on the body of white rat ------ Take a dropper to take boiling water in the beaker (boiling --- point 96. 〇5 drops on the body part of white mouse body jijL ----------- 200538139 0, 30 ,, --- Spray normal temperature water in a spray-type container to the affected part of the mouse, spray the composition containing the spray-type composition on the affected part of the mouse, and wipe the eyes with the forefoot at 2,00. Exudate white milk affected area was red, non-inflammatory discharge, frequently wiped the eyes before the foot, and the composition was sprayed on the affected part of the mouse for a second time. The first time the normal temperature water was sprayed on the affected part of the mouse at 9,00, the affected part of the mouse became red and gave birth every ^ ^ silk 12,00, the third time The composition was sprayed on the mouse's affected area for a second time with warm water. The mouse's foot was swabbed A before, and turned to _ body close to the affected area. The affected area of the mouse turned red, pink 15'00. 4 silk 19,00 ,, ---_ The affected part of the rat is red and the blood turns, and the seal gradually disappears. The affected part of the rat is red and gradually disappears. 23f00M ____ The affected part of the rat is red and the blood is gradually disappeared. — The color of the affected part of the pink rat was 45,000, and the color of the affected part of the pink rat was not known. The result was not known. The white gas in the test group was sprayed with the first composition 200538139 at 30 seconds. Eyes, and turned to stick to the affected area, which can indicate that the composition is irritating. At 2 minutes, the experimental group had no exudate in the affected area, while the control group had bloodshot and exudate in the affected area, which could explain the composition. When the skin is burned, it has an immediate recovery effect, and the heat dissipation function is immediately displayed; and the golden rescue time of a burn is only within three minutes, and if it exceeds three minutes, the treatment time will be extended. At 15 minutes, In the test group, the affected part of the rat was pink, while in the control group, the affected part still had bloodshot blood, which can further explain the importance of the golden rescue time and the effect of the composition on burns. By using the composition to treat the burned rats, the The recovery time will be shortened, and the recovery time of white rats that have not been treated with the composition will be nearly doubled. 3.2 Clinical trial experimental group: Male control group scalded by boiling water. Control group: scalded by boiling water When the male experimental male was burned, he immediately sprayed the traditional Chinese medicine composition prepared in Example 1 after spraying for 3 to 4 minutes, and the affected part showed redness, and then sprayed the traditional Chinese medicine composition a second time. After 5 minutes, although the affected part still had redness, but there was no other reaction on the skin appearance, the third time the traditional Chinese medicine composition was sprayed, and the patient's skin appearance was normal. After 10 minutes of spraying again, the patient did not have blisters and hair The red phenomenon disappeared. The male in the control group did not spray the 12 200538139 traditional Chinese medicine composition prepared in Example 1 when he was burned, and healed and left scars. The disease was treated according to the present invention for almost one month. X π a For those who are familiar with the technology and changes, it is beyond the scope and spirit of the present invention. Although the present invention has described specific preferred specific matters, it must be understood that the present invention should not be unduly limited to such specific entities. As a matter of fact, in implementing the described mode of the present invention, different amendments obvious to those skilled in the art are also covered by the following patent applications.

【圖式簡單說明】 (一)圖式部分 無 (二)元件代表符號 無[Schematic description] (I) Schematic part None (II) Symbols for components None

1313

Claims (1)

200538139 拾、申請專利範圍: 1 種用於治療皮膚黴菌感染之中藥組成物,其係 έ水片薄荷腦和地膚子之醇萃取物,其中冰片與薄荷 腦之重量比為1:3。 二2 ·如申請專利範圍第i項所述之中藥組成物,其中 及地膚子之醇萃取物為乙醇萃取物。 3 · 一種用於治療燒㈣之中藥組成物,其係包含冰 片、;4荷腦和地膚+夕含# 贗千之知卒取物,其中冰片與薄荷腦之重 篁比為1:3。 請專利範圍第3項所述之中藥組成物,其中 Μ地膚子之醇萃取物為乙醇萃取物。 5:—種製備用於治療皮膚黴菌感染之中藥組成物的 1:3的比例混合成液體 U)將冰片和薄荷腦以重量比為 (b)將地膚子浸於藥用200538139 Scope of patent application: A Chinese medicinal composition for the treatment of skin fungal infections, which is an alcohol extract of menthol and menthol, in which the weight ratio of borneol to menthol is 1: 3. 22 • The traditional Chinese medicine composition as described in item i of the scope of the patent application, wherein the alcohol extract of the scutella is ethanol extract. 3 · A Chinese medicinal composition for treating burnt tincture, which contains borneol; 4 lotus brain and earth skin + Xi Han # 赝 千 之 知 兵 取 物, wherein the weight ratio of borneol to menthol is 1: 3 . The Chinese medicine composition as described in item 3 of the patent scope, wherein the alcohol extract of M. scutellae is an ethanol extract. 5: a 1: 3 ratio of a traditional Chinese medicine composition prepared for the treatment of skin fungal infections is mixed into a liquid U) borneol and menthol are used in a weight ratio of (b) immersed in the medicinal preparation 逢濾淨;& 債内後尨過-段時間將地7 ⑷將⑷與⑻之溶液以任意比例混合而得。 6 .如令請專利範圍第5項所 驟係將地膚子浸於¥用 法,其中該(b 於樂用酒精内兩週後將地膚子逢濾淨。 7·如_請專利範圍第5項所述之方法 驟之地膚子與藥用酒精 、"(b) 灼马1錢·.0.1至1公升。 8.如申請專利範圍第5項所述 驟之地膚子與藥用酒精之比 /其中該(b) W碲1錢·· 0·5公升。 14 200538139 9如申請專利範圍第5項所述之方法,其中該(c)步 驟係將⑷與⑻之溶液以1:10至10:1的比例混合。 I 〇 ·如申請專利範圍第5項所述之方法,其♦該 步驟係將⑷與⑻之溶液以1:1的比例混合。 ^ II 一種製備用於治療燒燙傷之中藥組成物的方、本 ,包括: 沄 •⑷將冰片和薄荷腦以重量比為1:3的比例混合成液體 、(^ )將地膚子浸於藥用酒精内後經過一段時間將地膚子 逢濾、淨;及 ⑷將(a)與(b)之溶液以任意比例混合而得。 …丰1 2 ·如申請專利範圍第1 1項所述之方法,其中該 。乂驟係將地膚子浸於藥用酒精内兩週後將地膚子渣滤淨 如申凊專利範圍第1 1項所述之方法,其中 驟之地膚子與藥用酒精之比例為^錢幻至1公升 ⑻/驟4 ·如巾請專利範圍第11項所述之方法,其中 之地膚子與藥用酒精之比例為!錢:0.5公升。 ⑷牛1驟Γ如中請專利範圍第11項所述之方法,其中 、糸將⑷與(b)之溶液以1:1〇至1〇:1的比例混合。 ^如巾請專利範圍第^項所述之方法,其中 拾;^⑷與⑻之溶液以1:1的比例混合。 無 15 200538139 柒、指定代表圖: (一) 本案指定代表圖為:第( )圖。 (二) 本代表圖之元件代表符號簡單說明: 無 捌、本案若有化學式時,請揭示最能顯示發明特徵的化學式Every filter is cleaned; & After the debt is passed-for a period of time, the ground is 7 ⑷ The solution of ⑷ and ⑻ is mixed in an arbitrary ratio. 6. If the item 5 of the scope of patent is requested, the dermatome is immersed in the usage of ¥, where (b) the dermatome is filtered after two weeks in the alcohol for use. The method described in Item 5 and the medicinal alcohol, " (b) Shaoma 1 Qian · .0.1 to 1 liter. 8. The method described in item 5 of the patent application scope The ratio of alcohol used / wherein the (b) W tellurium 1 ··· 0.5 liter. 14 200538139 9 The method as described in item 5 of the scope of patent application, wherein the step (c) is a solution of rhenium and rhenium to Mixing at a ratio of 1:10 to 10: 1. I. The method described in item 5 of the scope of the patent application, wherein this step is to mix a solution of rhenium and rhenium in a ratio of 1: 1. ^ II A preparation Prescription and composition of traditional Chinese medicine composition for treating burns and scalds, including: 沄 • ⑷ Mix borneol and menthol in a ratio of 1: 3 by weight to form a liquid, (^) after immersing earthworm in medical alcohol After a period of time, the ground skin is filtered and cleaned; and (i) is obtained by mixing the solutions of (a) and (b) in any ratio.… Feng 1 2 · If the number 11 of the scope of patent application The method described above, wherein the step is immersed in the medicinal alcohol for two weeks, and the dregs of the phloem are filtered as described in item 11 of the scope of patent application, wherein The ratio to medicinal alcohol is ^ Qian Huan to 1 liter. / Step 4 · For the method described in item 11 of the patent scope, the ratio of dermatite to medicinal alcohol is! Money: 0.5 liter. ⑷ The method described in item 11 of the Chinese Patent Application, wherein 骤 mixes ⑷ with the solution of (b) in a ratio of 1:10 to 10: 1. ^ Please refer to the patent application No. ^ The method described in item 1, in which the solution of ^ ⑷ and ⑻ is mixed in a ratio of 1: 1. None 15 200538139 柒. Designated representative map: (1) The designated representative map in this case is: () Figure. (2) This A brief description of the representative symbols of the components of the figure: No, if there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention
TW93113892A 2004-05-18 2004-05-18 Chinese herbal medicine combo for treatment of derma fungus infection or burn TW200538139A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631440A (en) * 2012-04-16 2012-08-15 荣昌制药(淄博)有限公司 External traditional Chinese medicine preparation for treating burns and scalds as well as preparation method and quality detection method of preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102631440A (en) * 2012-04-16 2012-08-15 荣昌制药(淄博)有限公司 External traditional Chinese medicine preparation for treating burns and scalds as well as preparation method and quality detection method of preparation

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