TW200521430A - Fluidic circuits for sample preparation including bio-discs and methods relating thereto - Google Patents

Fluidic circuits for sample preparation including bio-discs and methods relating thereto Download PDF

Info

Publication number
TW200521430A
TW200521430A TW093122184A TW93122184A TW200521430A TW 200521430 A TW200521430 A TW 200521430A TW 093122184 A TW093122184 A TW 093122184A TW 93122184 A TW93122184 A TW 93122184A TW 200521430 A TW200521430 A TW 200521430A
Authority
TW
Taiwan
Prior art keywords
channel
sample
chamber
buffer
fluid communication
Prior art date
Application number
TW093122184A
Other languages
English (en)
Chinese (zh)
Inventor
Horacio Kido
James R Norton
James H Coombs
Original Assignee
Nagaoka Kk
Burstein Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagaoka Kk, Burstein Technologies Inc filed Critical Nagaoka Kk
Publication of TW200521430A publication Critical patent/TW200521430A/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Centrifugal Separators (AREA)
  • External Artificial Organs (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
TW093122184A 2003-07-25 2004-07-23 Fluidic circuits for sample preparation including bio-discs and methods relating thereto TW200521430A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48997803P 2003-07-25 2003-07-25

Publications (1)

Publication Number Publication Date
TW200521430A true TW200521430A (en) 2005-07-01

Family

ID=34115336

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093122184A TW200521430A (en) 2003-07-25 2004-07-23 Fluidic circuits for sample preparation including bio-discs and methods relating thereto

Country Status (4)

Country Link
US (1) US20070274863A1 (cg-RX-API-DMAC7.html)
JP (1) JP2007500351A (cg-RX-API-DMAC7.html)
TW (1) TW200521430A (cg-RX-API-DMAC7.html)
WO (1) WO2005011830A2 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006242872A (ja) * 2005-03-04 2006-09-14 Kyocera Corp 分離装置及び該分離装置を備えた測定装置
JP5139263B2 (ja) * 2005-04-14 2013-02-06 ギロス・パテント・エービー 液体プラグ
WO2006110095A1 (en) * 2005-04-14 2006-10-19 Gyros Patent Ab A microfluidic device with finger valves
EP1949962A1 (en) * 2007-01-25 2008-07-30 F.Hoffmann-La Roche Ag Device and method for separating a liquid component of a blood sample, and analyzer apparatus comprising such a device
KR100941415B1 (ko) * 2007-10-23 2010-02-10 삼성전자주식회사 액체 바코드 및 액체 바코드 판독 장치
KR100958307B1 (ko) * 2008-01-30 2010-05-19 한국과학기술연구원 나노채널이 집적된 3차원 금속 나노와이어 갭 전극을포함하는 바이오센서, 그 제작방법 및 상기 바이오센서를포함하는 바이오 디스크 시스템
US7947186B2 (en) 2008-05-22 2011-05-24 Statspin, Inc. Centrifugal device and method for fluid component separation
WO2011160015A2 (en) * 2010-06-17 2011-12-22 Abaxis, Inc. Rotors for immunoassays
CN102441356B (zh) * 2010-10-12 2013-08-21 扬博科技股份有限公司 离心式微流体装置
KR101956265B1 (ko) 2011-03-24 2019-06-24 바이오서핏 에스.에이. 마이크로 유체 장치의 액체 흐름 순서 제어
JP5923127B2 (ja) * 2013-03-29 2016-05-24 富士フイルム株式会社 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法
CN105865983A (zh) * 2015-01-22 2016-08-17 广明光电股份有限公司 生物碟片检测装置
WO2022136848A1 (en) * 2020-12-22 2022-06-30 Oxford Immune Algorithmics Ltd Wafer for carrying biological sample

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901658A (en) * 1974-07-30 1975-08-26 Us Energy Whole blood analysis rotor assembly having removable cellular sedimentation bowl
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
DE3044372A1 (de) * 1980-11-25 1982-07-08 Boehringer Mannheim Gmbh, 6800 Mannheim Rotoreinheit mit einsatzelementen fuer einen zentrifugalanalysator
FR2503866A1 (fr) * 1981-04-14 1982-10-15 Guigan Jean Dispositif pour delivrer une dose determinee d'un echantillon de liquide dans une cellule et procede associe
FR2572533B1 (fr) * 1984-10-26 1986-12-26 Guigan Jean Procede destine a realiser l'analyse medicale d'un echantillon liquide a l'aide d'au moins un reactif liquide et dispositif pour la mise en oeuvre du procede
US5173262A (en) * 1987-07-17 1992-12-22 Martin Marietta Energy Systems, Inc. Rotor assembly and method for automatically processing liquids
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5242606A (en) * 1990-06-04 1993-09-07 Abaxis, Incorporated Sample metering port for analytical rotor having overflow chamber
US5122284A (en) * 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5173193A (en) * 1991-04-01 1992-12-22 Schembri Carol T Centrifugal rotor having flow partition
US5061381A (en) * 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
JPH05507878A (ja) * 1990-06-15 1993-11-11 カイロン コーポレイション 組込みアッセイアセンブリおよび装置
SE9100392D0 (sv) * 1991-02-08 1991-02-08 Pharmacia Biosensor Ab A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means
US5550063A (en) * 1991-02-11 1996-08-27 Biostar, Inc. Methods for production of an optical assay device
US5698299A (en) * 1991-02-28 1997-12-16 Dyconex Patente Ag Thin laminated microstructure with precisely aligned openings
WO1993019827A1 (en) * 1992-04-02 1993-10-14 Abaxis, Inc. Analytical rotor with dye mixing chamber
FR2705693B1 (fr) * 1993-05-24 1995-07-28 Neuchatel Universite Procédé de fabrication d'un dispositif micro-usiné à contenir ou à véhiculer un fluide.
SE501380C2 (sv) * 1993-06-15 1995-01-30 Pharmacia Lkb Biotech Sätt att tillverka mikrokanal/mikrokavitetsstrukturer
US5409665A (en) * 1993-09-01 1995-04-25 Abaxis, Inc. Simultaneous cuvette filling with means to isolate cuvettes
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
WO1995011755A1 (en) * 1993-10-28 1995-05-04 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US6287517B1 (en) * 1993-11-01 2001-09-11 Nanogen, Inc. Laminated assembly for active bioelectronic devices
US5627041A (en) * 1994-09-02 1997-05-06 Biometric Imaging, Inc. Disposable cartridge for an assay of a biological sample
US6327031B1 (en) * 1998-09-18 2001-12-04 Burstein Technologies, Inc. Apparatus and semi-reflective optical system for carrying out analysis of samples
GB9418981D0 (en) * 1994-09-21 1994-11-09 Univ Glasgow Apparatus and method for carrying out analysis of samples
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
SE9502258D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Biotech Ab Method for the manufacture of a membrane-containing microstructure
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US6042684A (en) * 1996-04-01 2000-03-28 Toolex Alpha Ab Method and apparatus for glueing together disc elements
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
US5755913A (en) * 1996-12-06 1998-05-26 Liaw; Der-Jang Adhesive-free adhesion between polymer surfaces
AU7591998A (en) * 1997-05-23 1998-12-11 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5932799A (en) * 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
US6013513A (en) * 1997-10-30 2000-01-11 Motorola, Inc. Molecular detection apparatus
WO1999034920A1 (en) * 1998-01-12 1999-07-15 Massachusetts Institute Of Technology Method and apparatus for performing microassays
US6342395B1 (en) * 1998-04-22 2002-01-29 The Regents Of The University Of California Compact assay system with digital information
US6391541B1 (en) * 1999-05-28 2002-05-21 Kurt E. Petersen Apparatus for analyzing a fluid sample
US6527432B2 (en) * 2000-05-15 2003-03-04 Tecan Trading Ag Bidirectional flow centrifugal microfluidic devices
AU2002227181A1 (en) * 2000-11-16 2002-05-27 Burstein Technologies, Inc. Optical biodiscs with reflective layers
EP1410045A2 (en) * 2000-11-22 2004-04-21 Burstein Technologies, Inc. Apparatus and methods for separating agglutinants and disperse particles
US20020076354A1 (en) * 2000-12-01 2002-06-20 Cohen David Samuel Apparatus and methods for separating components of particulate suspension
US7079468B2 (en) * 2000-12-08 2006-07-18 Burstein Technologies, Inc. Optical discs for measuring analytes

Also Published As

Publication number Publication date
JP2007500351A (ja) 2007-01-11
WO2005011830A3 (en) 2005-12-29
WO2005011830A2 (en) 2005-02-10
US20070274863A1 (en) 2007-11-29

Similar Documents

Publication Publication Date Title
US7390464B2 (en) Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US20020076354A1 (en) Apparatus and methods for separating components of particulate suspension
US20070280859A1 (en) Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US6965433B2 (en) Optical biodiscs with reflective layers
JP4571129B2 (ja) 反応試薬区域に流体を均一に塗布する方法
US20020196435A1 (en) Apparatus and methods for separating agglutinants and disperse particles
AU2011211319B2 (en) Centrifugal micro-fluidic device and method for detecting analytes from liquid specimen
JP4869602B2 (ja) 被検物をマイクロ流体デバイスの多チャネルに分割する方法及び装置
CN103913562B (zh) 多通道微流体光盘检测系统及其方法
US20050037484A1 (en) Optical bio-discs including spiral fluidic circuits for performing assays
US7077996B2 (en) Methods and apparatus for blood separation and analysis using membranes on an optical bio-disc
EP2957890A1 (en) Cartridge with a rotatable lid
CN108449996A (zh) 微流体装置及其使用方法
US20030104486A1 (en) Methods and apparatus for detecting and quantifying lymphocytes with optical biodiscs
US20030113925A1 (en) Nuclear morphology based identification and quantification of white blood cell types using optical bio-disc systems
US5399486A (en) Disposable unit in diagnostic assays
JP2007501407A (ja) 多様な細胞タイプの検出および定量に使用される方法および装置並びにこれを行うための光バイオディスクの使用
JP2007500351A (ja) バイオディスクを有するサンプル調製用流体回路及びそれに関連した方法
US20030077627A1 (en) Transmissive optical disc assemblies for performing physical measurements and methods relating thereto
US6582912B1 (en) Device, method and apparatus for implementing the method, for dosing at least a particular constituent in a product sample
US20050014249A1 (en) Chromatographic analysis on optical bio-discs and methods relating thereto
EP1644184A2 (en) Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays
US20040226348A1 (en) Magnetic assisted detection of magnetic beads using optical disc drives
US8652407B1 (en) Self-contained assay device
EP4023338A1 (en) Cartridge and optical measurement of an analyte with said cartridge