TW200520773A - Nano compound collagen - Google Patents
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200520773 五、發明說明α) 技術領域: ’ 本發明為有關一種奈米複合膠原蛋白,乃係將由動物 體上取得的膠原蛋白,經過水解萃取分子量為50Kdalton 以下,濃度在0. 05-25%之小分子膠原蛋白,於其中混入卜 200 ppm奈米光觸媒複合銀粒子、1-5 0 Oppm光觸媒複合奈米 鐵及左旋維他命C,再調整其PH值使接近皮廣值6 ± 3左右 ,促使成對人體皮膚具親合性之液態乳液,使減小膠原蛋 白之分子量,以達易於滲入真皮層及為肌膚所吸收,而不 致因使用過多無法進入真皮層造成浪費,亦可藉由奈米光 觸媒複合銀粒子之循環殺菌除菌機制,使產生更深一層清 潔:肌膚抑菌之作用,以減少面皰、青春痘··等產生,奈米 鐵則有刺激膠原蛋白修復皮廣之啟動因子作用,可加速皮 廣細胞的修復機制,並減低皮膚對於膠原蛋白所引發的過 敏反應,另左旋維他命C則可協助細胞更有效吸收膠原蛋 白’並穩定膠原蛋白在皮膚中的組成,使更能維持年輕及 肌膚的彈性,致可達增進膠原蛋白使用之效益者。 先前技術: 自古埃及時代開始,人們即不斷在尋求美麗的方法, 時至今日,最熱門的保養勝品首推膠原蛋白,而膠原蛋白 普遍存在人體中,包括皮膚、骨骼、軟骨、肌腱、眼球中 :其中,皮膚的7 0 %即是由膠原蛋白所構成。致膠原蛋白 對於防止皮膚老化、防止皺紋產生,甚至於去除觖紋具有 極大的功效,因此,近幾年來膠原蛋白的化粧品、保養品 200520773 五、發明說明(2) - 逐漸變得炙手可熱。 然市面上的膠原蛋白幾乎全為分子量大的膠原蛋白, 若藉由塗抹於皮膚表面,膠原蛋白無法渗入毛孔進入真皮 層’因此無法有效被肌膚細胞所吸收及利用,反而形成浪 費及阻礙。而且,為了在室溫下保夸膠原蛋白,大部分產 品皆添加有人工抗菌劑,對於皮膚細胞而言,更添加了一 層負擔❶當大眾花了金錢取得一樣1品時,當然希望能夠 獲得最大的效益,但在以往的膠原蛋白產品中,只一昧的 強調膠原蛋白,事實上尚須其他輔助成分,才可加速促進 細胞接受膠原蛋白,是以針對於此,而有再加研究改進之 必要。 内容: 有鑑於此,本發明人乃積十數年從事膠原蛋白產 品 究、設計之經驗,悉心研究,竭盡心智,針對上述^題, 尋求改良之方法,並經過多次之實驗試做,終於發明出此 一奈米複合膠原蛋白。 本發明之主要目的在提供一種奈米複合膠原蛋白,乃 係將由動物趙上取得的勝原蛋白,經過水解萃取分子量為 50Kdalton以下,濃度在〇.05»25%之小分子膠原蛋白,於 其中混入l-2〇〇Ppm奈米光觸媒複合銀粒子,再調整其pH:值 像接近皮廣值6土 3左右,促使成對人艘皮廣具親合性之液 態乳液•使減小膠原蛋白之分子I,以達易於滲入真皮房 及為肌;I所吸收,料致因使用過多無法進人真皮層造成200520773 V. Description of the invention α) Technical field: 'The present invention relates to a kind of nano-composite collagen, which is a collagen obtained from an animal body and subjected to hydrolysis and extraction to a molecular weight of 50 Kdalton or less and a concentration of 0.05 to 25% of Small molecular collagen, mixed with 200 ppm nano-photocatalyst composite silver particles, 1-5 0 Oppm photo-catalyst composite nano-iron and L-vitamin C, and then adjust its pH value to close to the skin wide value of about 6 ± 3 A liquid emulsion with affinity for human skin, which reduces the molecular weight of collagen so that it can easily penetrate into and be absorbed by the skin without causing waste due to excessive use and inability to enter the dermis. It can also be compounded by nano-photocatalyst The cycle of sterilization and sterilization of silver particles produces a deeper layer of cleansing: the skin's bacteriostatic effect can reduce the occurrence of facial blisters, acne, etc., and nano iron can act as a stimulating factor that stimulates collagen to repair skin, which can accelerate Skin cell repair mechanism, and reduce the skin's allergic response to collagen, while L-vitamin C can help cells more Absorption of collagen 'composition and stability of collagen in the skin, so that more of the young and to maintain skin elasticity, promotion of efficiency up induced by the use of collagen. Prior technology: Since the ancient Egyptian era, people have been looking for beautiful methods. Today, the hottest maintenance product is collagen, which is commonly found in the human body, including skin, bones, cartilage, tendons, and eyeballs. Middle: Among them, 70% of the skin is composed of collagen. Collagenogenic has great effect on preventing skin aging, preventing wrinkles, and even removing wrinkles. Therefore, in recent years, collagen cosmetics and skin care products 200520773 V. Description of the invention (2)-It has gradually become hot. However, almost all collagens on the market are collagens with large molecular weight. If they are applied to the skin surface, collagen cannot penetrate into the pores and enter the dermis layer. Therefore, it cannot be effectively absorbed and used by skin cells, but it is wasteful and hindered. In addition, in order to maintain collagen at room temperature, most products are added with artificial antibacterial agents. For skin cells, a layer of burden is added. When the public spends money to obtain the same product, of course, they hope to obtain the maximum In the past collagen products, only the collagen was emphasized, and in fact, other auxiliary ingredients were needed to accelerate the promotion of collagen acceptance by the cells. Therefore, research and improvement have been aimed at this. necessary. Contents: In view of this, the inventor has accumulated more than ten years of experience in research and design of collagen products, researched carefully, and devoted himself to finding ways to improve the above-mentioned problems, and after many experiments and trials, finally This nano composite collagen was invented. The main object of the present invention is to provide a nano-composite collagen, which is obtained by hydrolyzing the vicinal protein obtained from the animal Zhao, with a molecular weight of less than 50 Kdalton and a concentration of 0.050 »25% of small-molecule collagen. l-2〇〇Ppm nano-photocatalyst composite silver particles, and then adjust its pH: the value is close to the skin wide value of about 6 soil 3, which promotes the pair of human skin skin wide affinity liquid emulsion Molecule I, which is easy to penetrate into the dermis and is a muscle; I absorbed, it is expected that it can not enter the dermis due to excessive use
第6頁 200520773 五、發明說明(3) 浪費’且可藉由光觸媒複合銀粒子之循環殺菌除菌機制, 使產生更深一層清潔肌虏抑菌之作用,以減少面皰、青春 痘、細菌性異位性皮膚炎··等產生,同時可避免人工抗菌 劑,對皮膚細胞造成負擔之實用發明者。Page 6 200520773 V. Explanation of the invention (3) Waste ”and the sterilization and sterilization mechanism of photocatalyst composite silver particles can be used to produce a deeper layer of muscle cleansing and bacteriostasis, so as to reduce facial blisters, acne, and bacterial alien It is a practical inventor that produces orthotopic dermatitis, etc., while avoiding artificial antibacterial agents and placing a burden on skin cells.
本發明之次要目的在提供一種奈米複合谬原蛋白,為 將由動物體上取得的膠原蛋白,經過水解萃取分子量為 SOKdalton以下,濃度在〇·〇5-25%之小分子膠原蛋白,於 其中混入l-200ppm奈米光觸媒複合銀粒子及卜5〇〇ρριη光觸 媒複合奈米鐵,再調整其ΡΗ值使接近皮膚值6 ± 3左右,促 使成對人趙皮膚具親合性之液態乳液,使可增進皮膚的吸 收能力及產生抑菌作用外,尚可以奈米鐵刺激膠原蛋白啟 動修復皮廣之作用,使加速皮廣細胞的修復機制,並減低 皮膚對於膠原蛋白所引發的過敏反處之實用發明者。A secondary object of the present invention is to provide a nano-composite protein, in order to extract collagen obtained from an animal by hydrolysis, and extract small-molecular-weight collagen having a molecular weight below SOKdalton and a concentration of 0.05 to 25%. It is mixed with 1-200ppm nano-photocatalyst composite silver particles and 500-µρριη photocatalyst composite nano-iron, and then adjusted its pH value to be close to the skin value of about 6 ± 3, which promotes a pair of human Zhao skin affinity liquid emulsion In addition to enhancing the skin's ability to absorb and produce bacteriostatic effects, nano-iron can stimulate collagen to initiate the role of skin repair, accelerate the repair mechanism of skin cells, and reduce the skin's allergic reaction to collagen. Practical inventor of the place.
本發明之再一目的在提供一種奈米複合膠原蛋白,為 將由動物體上取得的膠原蛋白,經過水解萃取分子量為 50Kdalton以下’濃度在〇〇5_25%之小分子膠原蛋白,於 其中混入1-20 Oppm奈米光觸媒複合銀粒子及左旋維他命c ,再調整其PH值使接近皮膚值6 ± 3左右,促使成對人體皮 膚具親合性之液態乳液,使可增進皮廣的吸收能力及產生 抑菌作用外’尚可以左旋維他命C協助細胞更有效吸收膠 原蛋白,並穩定膠原蛋白在皮膚中組成之實用創作者。 實施方式: 兹就本創作之作用及其它目的,配合流程圖式詳細說Still another object of the present invention is to provide a nano-composite collagen. In order to extract collagen obtained from an animal body by hydrolysis, a small-molecular-weight collagen having a molecular weight of 50 Kdalton or less and a concentration of 0.05 to 25% is mixed with 1- 20 Oppm nano-photocatalyst composite silver particles and L-vitamin c, and then adjust its PH value to be close to the skin value of about 6 ± 3, to promote a liquid emulsion with affinity for human skin, so as to improve the absorption capacity of the skin and produce In addition to bacteriostatic effects, it is a practical creator that can also help L-vitamin C to help cells absorb collagen more effectively and stabilize collagen in the skin. Implementation: I will explain in detail the role of this creation and other purposes, in conjunction with the flow chart.
200520773200520773
明如後,俾便更加了解: 皮解ί = 2由動物體上取得的膠原蛋白,經過處理後 八+藤;? i白量為5〇Kdalt〇n以下,濃度在0·05_25%之小 再於其中混入光觸媒搭載奈米級銀粒子組 奈米光觸媒複合銀粒子,另亦可加入卜5〇〇 ?彳奈米鐵及左旋維他命C,再調整其1"11值使接 近皮膚值土3左右,促使成對人體皮膚具親合性之液態乳 ^ =可將其加添於美容保養藥劑中,使調合製做成乳液 狀或膏狀之美容保養品。 由於本發明之膠原蛋白分子量為在5〇Kdalt〇n以下, 易於滲入真皮層及為肌膚所易吸收的狀態,而不致因使用 過多造成浪費,及阻礙其餘膠原蛋白為肌廣所吸收之情事 ;利用光觸媒搭載奈米級銀粒子,形成之奈 銀粒子,光觸媒之強氧化特性…有機物、;:媒;: 等,加以氧化分解成水及二氧化碳,而自然去除消滅,使 不致產生殘留披覆、發臭、病菌滋長等問題,並促進銀粒 子之殺菌特性,致可啟動抑菌機制)因而不需額外添加増 加肌膚負擔的抗菌劑,光觸媒複合銀粒子的抑菌機制只針 對細菌,不僅可保持本配方的無菌,當塗抹於皮膚 '臉上 時’亦可在皮廣表面產生抑菌作用,使產生更深一層清潔 肌廣之作用,對於面皰、青春痘、細菌性異位性皮膚炎·. 等’可產生減緩及消滅的作用;另膠原蛋白並不是塗抹上 之後,即可產生快速反應,尚須有刺激它發生作用的物質 ’而奈米鐵即可作為膠原蛋白修復皮廣的啟動因子,加速After the Ming Dynasty, I will know more about: 皮 解 ί = 2 collagen obtained from the animal body, after processing eight + rattan; The white content is less than 50Kdalt〇n, the concentration is as small as 0.05-55%, and the photocatalyst is equipped with nano-grade silver particles, and the nano-photocatalyst composite silver particles are mixed into it. In addition, it is also possible to add 500-200 nanometers. Iron and L-vitamin C, then adjust its 1 " 11 value to be close to the skin value of about 3, to promote a pair of liquid milk with affinity for human skin ^ = it can be added to the beauty care agent, so that the blending system is made A lotion or creamy beauty care product. Because the molecular weight of the collagen of the present invention is less than 50Kdalton, it is easy to penetrate into the dermis and easily absorbed by the skin without causing waste due to excessive use, and hinder the remaining collagen from being absorbed by the muscle; The photocatalyst is equipped with nano-grade silver particles to form the nano-silver particles. The strong oxidation characteristics of the photocatalyst ... organic substances ;; media; etc., are oxidized and decomposed into water and carbon dioxide, and are naturally removed and eliminated, so that there is no residual coating, Odor, bacterial growth, etc., and promote the bactericidal properties of silver particles, which can activate the bacteriostatic mechanism) Therefore, no additional antibacterial agent is needed to increase the burden on the skin. The bacteriostatic mechanism of photocatalyst composite silver particles only targets bacteria and not only maintain The sterility of this formula, when applied to the skin 'face', can also produce a bacteriostatic effect on the broad surface of the skin, so as to produce a deeper layer of cleansing and broadening the skin, for facial pimples, acne, bacterial atopic dermatitis ... Waiting 'can have a slowing and eliminating effect; In addition, collagen does not have a rapid response after it is applied. Play a role in its excited species' as the nano-iron to repair skin collagen wide initiation factor, acceleration
200520773 五、發明說明(5) 皮膚細胞的修復機制,並減低皮廣對於膠原蛋白所引發的 過敏反應,奈米鐵更能引領膠原蛋白進入真皮層,提高膠 原蛋白的功效;又經實驗研究証明,增加左旋維他命C可 以使皮膚細胞增生膠原蛋白,左旋維他命c也是膠原蛋白 合成時的必須要件,而左旋維他命C是人體每天必備的營 養素,因此,本發明中添加之左旋維他命C,可協助細胞 更有效吸收膠原蛋白,並且穩定膠原蛋白在皮膚中的組成 ,使更能維持年輕及肌膚的彈性,致可達增進皮膚對膠原 蛋白的吸收能力,及更一步啟動膠原蛋白的修復功效。 按專利法第十九條有明文規定:『稱發明者,謂利用 自然法則之技術思想之高度創作。』而本發明之方法從未 見於市場及刊物上,除能易於滲入真皮層為肌膚所吸收, 而不致造成浪費,亦可發揮清潔、修復肌膚及抑菌、增進 吸收之效用,是以功效及產業上有明顯之利用價值,而充 分符合發明專利之要件β200520773 V. Description of the invention (5) The repair mechanism of skin cells, and reduce the allergic reaction caused by collagen to collagen. Nano-iron can lead collagen into the dermal layer and improve the efficacy of collagen; it has been proved by experimental research. Increasing L-vitamin C can make skin cells proliferate collagen. L-vitamin c is also a necessary element for collagen synthesis, and L-vitamin C is an essential nutrient for the human body every day. Therefore, the addition of L-vitamin C in the present invention can help cells More effective absorption of collagen, and stabilize the composition of collagen in the skin, so that it can maintain youth and skin elasticity, which can increase the skin's ability to absorb collagen, and start the collagen repair effect. According to Article 19 of the Patent Law, "The inventor is called the creation of a high degree of technological thought using the laws of nature." "The method of the present invention has never been seen in the market and in publications. In addition to being easily penetrated into the dermis layer and absorbed by the skin without causing waste, it can also play a role in cleaning, repairing the skin, inhibiting bacteria, and enhancing absorption. It has obvious utilization value in the industry, and fully meets the requirements of the invention patent β
發明,致依本發明之創意精神及特徵,稍 者’亦應包括在本專利範圍之内。 綜上所述, 並非用以限制本發明 加變化修飾而成者, 200520773The invention is in accordance with the creative spirit and characteristics of the present invention, and the '' should also be included in the scope of this patent. In summary, it is not intended to limit the present invention by modification and modification, 200520773
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