TW200510304A - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- TW200510304A TW200510304A TW093125214A TW93125214A TW200510304A TW 200510304 A TW200510304 A TW 200510304A TW 093125214 A TW093125214 A TW 093125214A TW 93125214 A TW93125214 A TW 93125214A TW 200510304 A TW200510304 A TW 200510304A
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl
- alkoxy
- halo
- hydroxy
- cyano
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 102000007390 Glycogen Phosphorylase Human genes 0.000 abstract 2
- 108010046163 Glycogen Phosphorylase Proteins 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005549 heteroarylene group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0319690.4A GB0319690D0 (en) | 2003-08-22 | 2003-08-22 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200510304A true TW200510304A (en) | 2005-03-16 |
Family
ID=28460083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW093125214A TW200510304A (en) | 2003-08-22 | 2004-08-20 | Chemical compounds |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060199966A1 (enExample) |
| EP (1) | EP1660448A1 (enExample) |
| JP (1) | JP2007503421A (enExample) |
| AR (1) | AR045477A1 (enExample) |
| GB (1) | GB0319690D0 (enExample) |
| TW (1) | TW200510304A (enExample) |
| UY (1) | UY28485A1 (enExample) |
| WO (1) | WO2005019172A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3706810A (en) * | 1970-09-15 | 1972-12-19 | American Cyanamid Co | N-morpholinoalkyl-thieno(3,2-b)pyrrole-5-carboxamides |
| US4692522A (en) * | 1985-04-01 | 1987-09-08 | Merck & Co., Inc. | Benzofused lactams useful as cholecystokinin antagonists |
| US4668769A (en) * | 1985-08-02 | 1987-05-26 | Hoover Dennis J | Oxa- and azahomocyclostatine polypeptides |
| US4720503A (en) * | 1985-08-02 | 1988-01-19 | Merck & Co., Inc. | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
| US4599198A (en) * | 1985-08-02 | 1986-07-08 | Pfizer Inc. | Intermediates in polypeptide synthesis |
| FR2601368B1 (fr) * | 1986-07-08 | 1989-04-07 | Synthelabo | Derives de nitrofuranne, leur preparation et leur application en therapeutique. |
| DE3629545A1 (de) * | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| US4751231A (en) * | 1987-09-16 | 1988-06-14 | Merck & Co., Inc. | Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents |
| US5863903A (en) * | 1994-03-09 | 1999-01-26 | Novo Nordisk A/S | Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes |
| US5998463A (en) * | 1998-02-27 | 1999-12-07 | Pfizer Inc | Glycogen phosphorylase inhibitors |
| US6555569B2 (en) * | 2000-03-07 | 2003-04-29 | Pfizer Inc. | Use of heteroaryl substituted N-(indole-2-carbonyl-) amides for treatment of infection |
| GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| US7057046B2 (en) * | 2002-05-20 | 2006-06-06 | Bristol-Myers Squibb Company | Lactam glycogen phosphorylase inhibitors and method of use |
| US20040082641A1 (en) * | 2002-10-28 | 2004-04-29 | Rytved Klaus Asger | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| US7098235B2 (en) * | 2002-11-14 | 2006-08-29 | Bristol-Myers Squibb Co. | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds |
| BRPI0409952A (pt) * | 2003-04-30 | 2006-04-25 | Pfizer Prod Inc | agentes anti-diabéticos |
-
2003
- 2003-08-22 GB GBGB0319690.4A patent/GB0319690D0/en not_active Ceased
-
2004
- 2004-08-18 WO PCT/GB2004/003552 patent/WO2005019172A1/en not_active Ceased
- 2004-08-18 JP JP2006524409A patent/JP2007503421A/ja not_active Withdrawn
- 2004-08-18 US US10/567,798 patent/US20060199966A1/en not_active Abandoned
- 2004-08-18 EP EP04801875A patent/EP1660448A1/en not_active Withdrawn
- 2004-08-20 UY UY28485A patent/UY28485A1/es not_active Application Discontinuation
- 2004-08-20 TW TW093125214A patent/TW200510304A/zh unknown
- 2004-08-23 AR ARP040103021A patent/AR045477A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0319690D0 (en) | 2003-09-24 |
| WO2005019172A1 (en) | 2005-03-03 |
| US20060199966A1 (en) | 2006-09-07 |
| UY28485A1 (es) | 2005-03-31 |
| AR045477A1 (es) | 2005-10-26 |
| EP1660448A1 (en) | 2006-05-31 |
| JP2007503421A (ja) | 2007-02-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB0318464D0 (en) | Chemical compounds | |
| GB0318463D0 (en) | Chemical compounds | |
| IL151757A0 (en) | Glucopyranosyloxy benzylbenzene derivatives, medicinal compounds containing the same and intermediates for the preparation of the derivatives | |
| WO2008108380A3 (en) | Pyrrole compounds | |
| WO2007076092A3 (en) | Nitrogen- containing bicyclic hetroaryl compounds for the treatment of raf protein kinase-mediated diseases | |
| GB0021831D0 (en) | Chemical compounds | |
| EP1717238A4 (en) | FUNGICIDES HETEROCYCLIC COMPOUNDS | |
| MX2008000255A (es) | Activadores de urea glucocinasa. | |
| TW200510304A (en) | Chemical compounds | |
| MX2009003713A (es) | Inhibidor de progresion de enfermedad de alzheimer que contiene un compuesto heterociclico con estructura especifica. | |
| WO2003053988A3 (en) | Avermectin b1 derivatives having an aminosulfonyloxy substituent in the 4''-position | |
| ATE429429T1 (de) | Pharmazeutisches verfahren und damit hergestellte verbindungen | |
| WO2003072576A3 (en) | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them | |
| CA2241092A1 (en) | 1-methylcarbapenem derivatives | |
| EP1593666A4 (en) | AMINOALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | |
| TW200744589A (en) | Pharmaceutical composition | |
| WO2002026732A1 (en) | Benzodiazepine derivative | |
| TW200512214A (en) | Avermectin B1 and avermectin B1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"-or 4'-position | |
| MXPA02012589A (es) | Compuestos utiles para la preparacion de medicamentos con actividad inhibitoria de la fosfodiesterasa iv. | |
| UA88925C2 (en) | 4-nitroimidazole derivatives | |
| TW200420574A (en) | Avermectin-and avermectin monosaccharide derivatives substituted in the 4"-or 4'-position having pesticidal properties | |
| IL147348A0 (en) | Tricyclic compounds having spiro union | |
| WO2006024405A3 (en) | Derivatives of avermectin, avermectin monosaccharide and avermectin aglycone | |
| TW200504159A (en) | Monoazo compound and process for making same | |
| WO2003066647A3 (fr) | Synthese de molecules de type inositolphosphate glycanne: traitement des troubles de la proliferation cellulaire et de desordres metaboliques caracterises par une resistance a l'insuline |