TR2022003163T2 - OIL AND LIQUID ANTIFUNGAL COMPOSITIONS - Google Patents

Abstract

The subject invention comprises (i) at least one dithiocarbamate antifungal, (ii) at least one triazole antifungal, (iii) at least one pyrazole-carboxamide antifungal and (iv) at least one agrochemically acceptable anhydrous liquid carrier. An antifungal oil provides liquid compositions wherein the dithiocarbamate antifungal is suspended in the liquid carrier and the triazole antifungal and pyrazole-carboxamide antifungal are dissolved in the liquid carrier. The present invention also provides methods of use and preparation processes of the compositions disclosed herein.

Description

DESCRIPTION OIL LIQUID ANTIFUNGAL COMPOSITIONS In this application, the entire contents of which are incorporated herein by reference, as of September 4, 2019 Utilizing U.S. Provisional Application No. 62/895,602 on file.

Various publications are referenced throughout this application. Integrity of these documents The explanations in it are intended to explain more comprehensively the state of the art to which this invention relates. is incorporated by reference into this application.

FIELD TO WHICH THE INVENTION REFERS TO The invention in question includes (i) at least one dithiocarbamate antifungal, (ii) at least one triazole antifungal agent. inhibitor, (iii) at least one pyrazole-carboxamide antifungal and (iv) at least one agrochemical An antifungal oil liquid compositions comprising an anhydrous liquid carrier acceptable as where dithiocarbamate is suspended in an antifungal liquid carrier. and triazole antifungal and pyrazole-carboxamide antifungal, liquid carrier dissolves in it. The invention in question also provides the use of the compositions disclosed herein. It also provides methods and preparation procedures. BACKGROUND ART Dithiocarbamates are generally known to have effective antifungal activity.

However, a particular problem of these active substances is their relatively high instability.

This is especially true at low pH values and in the presence of nucleophilic agents, where C-S bonds and It is due to the low stability of the thiocarbamate function.

These active ingredients are formulated as solid formulations to improve their stability. can be done. Known solid powder formulations, such as Manzate® 75 WG (DuPont product), Polyram® DF (product from Nufarm) and Vondozeb 75 WG (product from Agrosimex).

However, solid formulations such as water-dispersible granules are known to be It has disadvantages. Some of these include poor dispersion in water, difficulties in measuring, compatibility with other components in the tank mixture and This may include the high cost of producing the formulations. In most cases, liquid products are nowadays preferable to the solid formulations mentioned above. is done. Liquid products, even under ULV (ultra-low volume) conditions, oil-based tarik Good for mixing with additives, water/oil formulations or oil formulations Agrochemical oil dispersions (OD) are anhydrous oils that may contain other dissolved active ingredients. Agricultural chemical active substances such as pesticides and plant protection chemicals in liquids are stable suspensions. Oil dispersions are mixtures of solid active substances that are insoluble in oil. It is particularly useful for formulating

Oil dispersion formulations to produce an aqueous composition used in plant protection It is a concentrate that is diluted with water before use. Make it possible to disperse in water Such formulations as; emulsifiers, dispersants and thickeners, foam other formulation components such as inhibitors and solid carriers. Oil Dispersions generally occur if the active ingredient is sensitive to water or if the oil is biodegradable to the pesticide. It is chosen if it needs to act as an assistant to improve performance. Oil Dispersions generally do not contain water. This prevents both the degradation of the active ingredient and This is to prevent phase separation of the formulation.

Oil dispersion formulations provide some advantages to the farmer. Usually in water Unstable active ingredients can now be formulated as solid suspensions.

Oil-based adjuvants can also be used with such formulations to increase effectiveness. can be combined. Additionally, the active ingredients are contained in a non-aqueous liquid carrier. suspension, possibly higher levels of active ingredient than would otherwise be possible. can lead to strength formulations. This is because the active ingredients are It has a solubility limit on the amount that can be added to the formulation.

Additionally, oil dispersion formulations are difficult to formulate. oil dispersion formulations often show phase separation after storage. Because, storage even at ambient temperatures may cause clumping effects, lump formation or It causes significant precipitation of the suspended phase. active ingredient and Depending on the density of the anhydrous liquid carrier used, the active ingredient particles It is also possible to separate the anhydrous liquid from the carrier. In some cases, the effects are reversible becomes irreversible.

As the need for new high-performance agrochemical compositions increases, these materials regulatory requirements due to more stringent standards for their toxicological and ecological properties. Number of chemicals approved for use in agrochemical compounds by authorities is decreasing. In this regard, the art involves increasing the effectiveness of the active ingredients at the same time. A method that allows the application rates of individual active ingredients to be reduced while preserving An antifungal composition is needed. In addition, a multiregional fungus two systemic antifungals (such as a triazole) antifungal and a pyrazole-carboxamide antifungal) The combination of active substances in the formulation reduces the resistance of diseases, It provides a solution that reduces rates, increases efficiency and reduces costs.

Based on the aspects discussed above, the art requires a multisite antifungal (e.g. a dithiocarbamate antifungal) with two systemic antifungals There is a need for a stable oil formulation that will contain

BRIEF DESCRIPTION OF THE INVENTION present invention, i) at least one dithiocarbamate antifungal, ii) at least one triazole antifungal, i) at least one pyrazole-carboxamide antifungal and provides an antifungal oil liquid composition, where the dithiocarbamate is suspended in an antifungal liquid carrier and triazole antifungal and pyrazole-carboxamide antifungal in liquid carrier It dissolves.

The present invention also an amount of at least one dithiocarbamate antifungal, an amount of at least one triazole antifungal and a combination containing some amount of at least one pyrazole-carboxamide antifungal It provides, where the combination protects against fungal infection of a plant or a locus treatment, the same amount of each antifungal should be applied alone. becomes more effective.

The present invention also an amount of at least one dithiocarbamate antifungal, an amount of at least one triazole antifungal and a combination containing some amount of at least one pyrazole-carboxamide antifungal It provides, where is the amount of dithiocarbamate antifungal, is the amount of triazole antifungal, and When the amount of pyrazole-carboxamide antifungal is applied together, the effect of a plant or In the treatment of a Iocus against a fungal infection, each antifungal is the same. It is more effective than applying small amounts alone.

The present invention also an amount of at least one dithiocarbamate antifungal, an amount of at least one triazole antifungal and a combination containing an amount of at least one pyrazole-carboxamide antifungal It provides, wherein the compound of formula I, when used alone, acts as a dithiocarbamate antifungal. amount less than the amount of the compound of Formula I that is effective as an antifungal being, where is the amount of triazole inhibitor when used alone, less than the antifungal effective amount of triazole antifungal being and/or where is the amount of pyrazole-carboxamide antifungal, pyrazole-carboxamide is the amount of antifungal When the inhibitor is used alone, the pyrazole-carboxamide antifungal It is less than the amount that is effective as a preventive measure.

The present invention also includes a method comprising any of the combinations disclosed herein. It provides a mixture.

The present invention also includes any of the combinations or mixtures disclosed herein. It provides an antifungal composition containing one.

The present invention also consists of combinations, mixtures or mixtures disclosed herein. involving the application to the plant or locus of an effective amount of either compound. to treat a plant or a site against fungal infection, thus protecting the plant or provides a method to treat the site for fungal infection.

The present invention also provides treatment against fungal infection of a plant or a plant. combinations, mixtures or compositions disclosed herein to It allows anyone to use it.

The present invention also provides treatment against fungal infection of a plant or a locus. combinations, mixtures and mixtures described herein for use in provides any of the combinations.

The present invention also consists of combinations, mixtures or mixtures disclosed herein. provides a package containing any of the combinations.

The present invention also consists of combinations, mixtures or mixtures disclosed herein. a process for preparing any of the compositions from separate component parts It provides.

DESCRIPTION OF THE FIGURES Figure 1 shows Phakopsora pachyrhizi affecting soybean plants of the BONUS cultivar. To control, tank mixtures of the same agents and tebuconazole, picoxystrobin, and compared to a three-way premix composition consisting of mankozeb (commercial standard) It shows the effectiveness of the premix compositions of Examples 1 and 2 (Study Uberlândia- MG/Made in Brazil).

Figure 2, Phakopsora cultivar M 5917 IPRO affecting soybean plants to control pachyrhizi, tank mixtures of the same agents plus tebuconazole, with a three-way premix composition of picoxystrobin and mancozeb (commercial standard). shows the effectiveness of the premix compositions of Examples 1 and 2 compared (The study was conducted in Ponta Grossa-PR/Brazil).

Figure 3 shows Phakopsora pachyrhizi affecting soybean plants of the BONUS cultivar. To control, tank mixtures of the same agents and tebuconazole, picoxystrobin, and compared to a three-way premix composition consisting of mankozeb (commercial standard) It shows the effectiveness of the premix compositions of Examples 1 and 2 (Study Rio verde-GO/Made in Brazil).

DETAILED DESCRIPTION OF THE INVENTION Definitions Unless otherwise stated, all technical and scientific terms used herein are will be generally understood by those of ordinary skill in the art. It has a meaning like this.

The term "stable" as used herein, when used in connection with a composition, It means that the composition is physically stable and chemically stable.

The term "chemically stable" as used herein means in a closed environment at a temperature of 54°C. After at least 2 weeks of storage in the package, a significant decrease in the active ingredients It means that no degradation has been observed. As used here meaning that no significant phase separation and/or precipitation is observed after storage. is coming.

Determined by Collaborative International Pesticides Analytical Council Ltd. (CIPAC) According to the testing protocol established by, i.e., Storage Acceleration Procedure (according to CIPAC MT is being evaluated. ClPAC test protocols, stability before and after storage It is the standard in the relevant industry to evaluate. Before and after storage other stability parameters such as pourability and concentrations of substances, using tests commonly used in the agrochemical industry can be evaluated. Stability after two years of storage at room temperature It can be evaluated under normal storage conditions. Stability, 2 weeks at 54°C or after 8 weeks at 40°C or after 12 weeks at 35°C or after 3 months at room temperature or under accelerated storage conditions after 2 weeks at 0°C. can be evaluated.

The term "combination" as used herein means simultaneous or simultaneous administration. refers to a collection of agrochemicals for application by .

As used herein, the term "simultaneous" means the application of agrochemicals. When used in conjunction with agrochemicals in a mixture, e.g. in a tank It means that it is applied in the mixture. For concurrent application combination, each containing an agrochemical combined before application It can be a mixture or separate containers.

As used herein, the term "simultaneous" means the application of agrochemicals. when used in conjunction with a single agrochemical from another agrochemical or at the same time or sufficiently close together, separately from the premix. application depends on the effectiveness of any of the agrochemicals alone at the same dose. Obtaining greater effectiveness than additive or additive or synergistic It means.

The term "mixture" as used herein means any substance in any physical form, e.g. blend, solution, suspension, dispersion, emulsion, alloy or similar refers to, but is not limited to combination.

The term "tank mix" as used herein means the combination, mixture, or one or more components of the composition during or after spray application. It means that it is mixed in a spray tank before application.

As used herein, the term "composition" means an agriculturally acceptable carrier. comprising at least one of the combinations or mixtures of the present invention. Compound, It may be a formulation, including a commercial formulation.

As used herein, the term "active" means the active ingredient, combination, mixture or When used in conjunction with an amount of the composition, it stimulates a plant to When applied to material, soil or a locus, it prevents fungus, pathogen and/or disease. active substance, combination, mixture or substance that provides agriculturally beneficial control It means an amount of the composition.

As used herein, the term "antifungal effective amount" means an amount that controls fungi. It means the amount of active ingredient commercially recommended for use.

For each active ingredient, which are generally stated as application rates of the commercial formulation The commercially recommended amount can be found on the label accompanying the commercial formulation. Commercial commercially recommended application rates of the formulation, the plant species to be controlled and It may vary depending on factors such as fungi.

The term "effective" as used herein refers to fungal infection of a plant or locus. When used in conjunction with a method for treating against agricultural without significantly interfering with the normal growth and development of the plant This means that it provides a beneficial level of treatment.

As used herein, "against fungal infection of a plant or a lily" The term "treat" refers to protecting the plant or site against fungal infection and/or It includes, but is not limited to, controlling fungal infection of the plant or ground. It is not.

As used here, "protection against fungal infection of the plant or a locus" The term "protection" refers to the protection of the plant or Iocus against fungal attack, the protection of the plant or protecting the locus from fungal disease and/or protecting the plant or locus from fungal disease It includes but is not limited to the prevention of infection.

As used herein, "controlling fungal infection of a plant or plant" The term refers to the control of fungal disease infecting the plant or locus, phytopathological phytopathological control of a plant or soil disease caused by fungi to control a plant or soil disease caused by fungi, plant or control of fungal attack on the locus, the plant or the fungus in the locus to reduce infection and/or infection of plants or plants caused by phytopathological fungi. It includes, but is not limited to, the treatment of soil disease.

As used here, "to protect the plant or locus against fungal attack" The term "effective" refers to the extended period of protection against fungal attack after application. and extending the period of protection against fungal attack, but is limited to It is not.

As used herein, the term “more effective for controlling fungal disease” means improve the effectiveness of fungal disease control and achieve a certain level of fungal control This includes, but is not limited to, reducing the time required to reach your destination.

The term "agriculturally acceptable carrier" as used herein refers to products used in agriculture or known and accepted techniques in the art for the preparation of compositions for use in horticulture. It means carriers.

The term "excipient" as used herein generally refers to substances that are not themselves active ingredients. However, it does not increase or is intended to increase the effectiveness of the antifungal with which it is used. It is defined as any substance. Auxiliaries, spreading agents, penetrants, It can be understood that it contains compatibility agents and drift retardants.

The term "agriculturally acceptable inert additives" as used herein means Substances that are not itself an active ingredient but are added to the composition, such as adhesive substances, surfactants, synergists, buffers, acidifiers, anti-oxidants, as any substances such as defoaming agents and thickeners is defined.

The term "plant" as used herein refers to the entire plant, plant organ (e.g. leaves, stems, twigs, roots, stems, limbs, sap, fruits, etc.), plant It contains the expression of cells and reproductive material of the plant.

As used herein, the term "plant" refers to field crops (soybeans, corn, wheat, rice, etc.), vegetable crops (potatoes, cabbage, etc.) and fruits (peaches, etc.). It includes the expression agricultural products.

As used herein, the term "propagating material" means the seeds and spores of the plant, all productive parts such as seedlings and bulbs, tubers, rhizomes, root stems, basal It should be understood that it refers to vegetative structures such as piths, stolons and buds.

The term "locus" as used herein refers only to those where the fungal infection has already occurred. areas where fungal infection has not yet emerged, but also It includes uncultivated areas as well as cultivated areas. Locus, soil and other It includes, but is not limited to, plant growth medium.

As used here, the term "ha" refers to hectare.

As used herein, the term "excipient" refers to surfactant(s), solvent(s), or means any chemical that does not have significant pesticide activity, such as adjuvant(s) is coming. Any combination, mixture or composition described herein is or more excipients may be added.

As used herein, the term "an" includes the singular and plural unless specifically stated otherwise. Contains. Therefore, the terms "one" or "at least one" are used interchangeably in this application. can be used.

Throughout the application, the descriptions of various embodiments use the term "comprising" and However, by one skilled in the art, in some special cases, "mainly from An arrangement can be described using the language "consisting of" or "consisting of" It will be understood.

The term "approximate" here specifically means ± 10% of the values stated in the range. Contains. Additionally, here you can find all ranges for the same component or feature. points, end points, can be combined independently and all intermediate points and ranges.

Given a range of parameters, all integers in that range and their decimals are also met as if whole numbers and tenths are clearly explained here. It is understood that it is provided by. For example, "0.1-80% by weight", 0.1% by weight, 02% by weight, 03% by weight, 0.4% by weight, 0.5% by weight, etc. up to 80% Contains.

All publications, patents and patent applications mentioned in this specification, each publication, The patent or patent application is specifically and individually incorporated herein by reference. are incorporated by reference into the specification in their entirety, as specified to be has been done.

The following examples illustrate, in some embodiments, the application of the present subject matter. illustrative, but should not be interpreted as limiting the scope of the present topic.

Considering the description and examples contained herein, which fall within the spirit and scope of the appended claims. Other embodiments which are understood by those of ordinary skill in the art when It becomes part of the invention. Find the specification, including examples It is intended to serve as an example only, without limiting its scope and essence.

Aspects and embodiments of the present invention will now be described.

Antifungal Oil Liquid Compositions Dithiocarbamate antifungals are normally formulated dry. triazole Antifungals are normally emulsifiable concentrates or suspensions It is formulated as concentrates where it can be emulsified It is known that concentrates are more efficient. It is a pyrazole-carboxamide fluxapyroxad, normally emulsifiable concentrates or suspension It is formulated as concentrates. In the art, a feature provided by the present invention dithiocarbamate antifungal, a triazole antifungal and a pyrazole-carboxamide There is a need for a stable oil composition containing antifungals.

In addition to being stable even after long storage periods, the The composition also provides protection against fungal infection of the plant or Iocus by applying the composition. To treat, use the same amount of each antifungal as a tank mix. in a way that is more effective than applying it or applying it separately. It increases the antifungal effectiveness of the active ingredients contained. of existing invention The composition is also used for treating plant or locus against fungal infection, WO a dithiocarbamate antifungal, a triazole antifungal, and a strobilurin antifungal. It is more effective than known three-agent compositions, including a composition containing

present invention, i) at least one dithiocarbamate antifungal, ii) at least one triazole antifungal, i) at least one pyrazole-carboxamide antifungal and provides an antifungal oil liquid composition, where the dithiocarbamate is suspended in an antifungal liquid carrier and triazole antifungal and pyrazole-carboxamide antifungal in liquid carrier It dissolves.

present invention, i) at least one dithiocarbamate antifungal, ii) at least one triazole antifungal, i) at least one pyrazole-carboxamide antifungal and It provides a stable anti-fungal oil liquid composition, where the dithiocarbamate is suspended in an antifungal liquid carrier and triazole antifungal and pyrazole-carboxamide antifungal in liquid carrier It dissolves.

In some embodiments, the dithiocarbamate antifungal is mancozeb, maneb, metiram, is selected from the group consisting of propineb, thiram, zinc thiazole, zineb and ziram.

In some embodiments, the dithiocarbamate is the antifungal mancozeb.

In some embodiments, triazole antifungal; bittanol, bromuconazole, ciproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol is selected from the group consisting of triticonazole and prothioconazole.

In some embodiments, the triazole antifungal is prothioconazole.

In some embodiments, the triazole antifungal is tebuconazole.

In some embodiments, pyrazole-carboxamide is an antifungal; benzovindiflupir, bixafen, consisting of fluxapyroxad, furametpyr, isopyrazam, penflufen, pentiopyrad and sedaxane. is selected from the group.

In some embodiments, the pyrazole-carboxamide antifungal is fluxapyroxad.

Chemical classes of antifungals as well as specific compounds of each class "The Pesticide Manual", the contents of which are incorporated herein by reference in their entirety. Eighteenth Edition" (British Crop Protection Council, Hampshire, UK, 2018) and additional See documentation (2008-2011).

In a preferred embodiment, the subject is a) mancozeb, b) tebuconazole, c) fluxapiroxad and d) an antifungal oil liquid composition comprising a non-aqueous liquid carrier, where mancozeb is suspended in a nonaqueous liquid carrier and tebuconazole is and fluxapiroxad is dissolved in the nonaqueous liquid carrier.

In another preferred embodiment, the subject is a) mancozeb, b) prothioconazole, c) an antifungal oil liquid composition comprising fluxapyroxad and d) a nonaqueous liquid carrier It is related to, where mancozeb is suspended in a non-aqueous liquid carrier and prothioconazole and fluxapiroxad are dissolved in non-aqueous liquid carrier.

In some embodiments, the amount of dithiocarbamate antifungal depends on the total weight of the composition. It is approximately 0.1-80% by weight based on In some embodiments, dithiocarbamate mushroom The amount of inhibitor is approximately 10-60% by weight based on the total weight of the composition.

In some embodiments, the amount of dithiocarbamate antifungal depends on the total weight of the composition. It is approximately 20-50% by weight based on In some embodiments, dithiocarbamate mushroom The amount of inhibitor is approximately 30-40% by weight based on the total weight of the composition.

In some embodiments, the amount of dithiocarbamate antifungal depends on the total weight of the composition. It is approximately 35% by weight based on

In some embodiments, the amount of dithiocarbamate antifungal in the composition is approximately 300-300 ml. It is 600 g/L. In some embodiments, the amount of dithiocarbamate antifungal in the composition It is approximately 400-500 g/L. In some embodiments, the dithiocarbamate in the composition is The amount of inhibitor is approximately 418 - 462 g/L. In some embodiments, the composition The amount of dithiocarbamate antifungal is approximately 440 g/L.

In some embodiments, triazole antifungal and pyrazole-carboxamide antifungal The amount together is approximately 0.1-20% by weight, based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 1-10% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 4-7% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 5-6% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 5.5% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 5.38% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 3-6% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 4-5% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 4.5% by weight based on the total weight of the composition. Some regulations, the amount of triazole antifungal and pyrazole-carboxamide antifungal together is approximately 4.25% by weight based on the total weight of the composition.

In some embodiments, the amount of triazole antifungal is based on the total weight of the composition. It is approximately 0.1-15% by weight. In some embodiments, the triazole antifungal The amount is approximately 1-10% by weight based on the total weight of the composition. Some In embodiments, the amount of triazole antifungal is based on the total weight of the composition. It is approximately 2-5% by weight. In some embodiments, the amount of triazole antifungal approximately 3-4% by weight based on the total weight of the composition. Some In embodiments, the amount of triazole antifungal is based on the total weight of the composition. It is approximately 3.5% by weight. In some embodiments, the amount of triazole antifungal approximately 3.57% by weight, based on the total weight of the composition. Some In embodiments, the amount of triazole antifungal is based on the total weight of the composition. It is approximately 1-4% by weight. In some embodiments, the triazole antifungal The amount is approximately 2-3% by weight, based on the total weight of the composition. Some In embodiments, the amount of triazole antifungal is based on the total weight of the composition. It is approximately 2.5% by weight. In some embodiments, the amount of triazole antifungal approximately 2.48% by weight based on the total weight of the composition.

In some embodiments, the amount of triazole antifungal in the composition is approximately 20-60 g/L.

In some embodiments, the amount of triazole antifungal in the composition is approximately 40-50 g/L.

In some embodiments, the amount of triazole antifungal in the composition is approximately 40.05-48.95 g/L. In some embodiments, the amount of triazole antifungal in the composition is approximately 44.5 g/L. In some embodiments, the amount of triazole antifungal in the composition is approximately 25-35 mL. g/L. In some embodiments, the amount of triazole antifungal in the composition is approximately 28.35- It is 34.65 g/L. In some embodiments, the amount of triazole antifungal in the composition is approximately It is 31.5 g/L.

In some embodiments, the amount of pyrazole-carboxamide antifungal is the total amount of the composition. It is approximately 0.1-10% by weight, based on weight. In some embodiments, pyrazole- The amount of carboxamide antifungal is by weight based on the total weight of the composition. It is approximately 0.1-5%. In some embodiments, the amount of pyrazole-carboxamide antifungal It is approximately 1-2% by weight based on the total weight of the composition. In some regulations, The amount of pyrazole-carboxamide antifungal depends on the total weight of the composition. It is approximately 1.7% by weight. In some embodiments, the pyrazole-carboxamide antifungal The amount is approximately 1.8% by weight, based on the total weight of the composition. Some In embodiments, the amount of pyrazole-carboxamide antifungal depends on the total composition of the composition. It is approximately 1.77% by weight, based on weight. In some embodiments, pyrazole- The amount of carboxamide antifungal is by weight based on the total weight of the composition. It is about 1.81%.

In some embodiments, the amount of pyrazole-carboxamide antifungal in the composition, It is approximately 15-30 g/L. In some embodiments, the pyrazole-carboxamide fungus in the composition The amount of inhibitor is approximately 19.13 - 25.88 g/L. In some embodiments, the composition The amount of pyrazole-carboxamide antifungal is approximately 22.5 g/L.

In some embodiments, the composition includes at least one non-3qu liquid carrier. Aqueous non-liquid carrier, aromatic hydrocarbons (e.g., toluene, 0-, m-, p-xylene, ethylbenzene, isopropylbenzene, tert-butylbenzene, naphthalenes, mono- or polyalkyl substituted naphthalenes), paraffins (e.g. octane, nonane, decane, undecane, dodecane, tridecane, tetradecane, pentadecane, hexadecane, hepta-decane, octa-decane, none-decane, eicosane, heneicosane, docosane, trichosanettacosane, chain isomers, and their chain isomers). petroleum, alcohols (e.g. 2-ethyl hexanol), ketones (e.g. acetophenone, cyclohexanone), vegetable oil (e.g. olive oil, kapok oil, castor oil, papaya oil, camellia oil, palm oil, sesame oil, corn oil, rice bran oil, peanut oil, cottonseed oil, soy bean oil, rapeseed oil, linseed oil, tung oil, sunflower oil, safflower oil, tall oil), alkyl ester of vegetable oils, (e.g. rapeseed oil methyl ester or rapeseed ethyl ester, rapeseed oil propyl esters, rapeseed oil butyl esters, soybean oil methyl ester, tall oil fatty acid esters etc.), diesel, mineral oil, alkyl amides (e.g. N,N-dimethyl decanamide), fatty acid amides (e.g. C1 -CS amines, alkylamines or 06 - 018 carboxylic acidic alkanolamines), fatty acids, tall oil fatty acids, alkyl esters of fatty acids (for example, Cl-C4 monohydric alcohol of C8 to O22 fatty acids such as methyl oleate, ethyl oleate, etc.) esters), modified vegetable oils and combinations thereof. and is not limited to these.

In some embodiments, the non-aqueous liquid carrier includes aromatic hydrocarbons, alkyl amides, consisting of alkyl esters of vegetable oils, alcohols, and any combination thereof is selected from the group.

In some embodiments, the total amount of anhydrous liquid carrier in the composition is It is approximately 0.1-80% by weight, based on weight. In some embodiments, the composition The total amount of anhydrous liquid carrier is by weight based on the total weight of the composition. It is approximately 1-60%. In some embodiments, the total amount of anhydrous liquid carrier in the composition, approximately 10-50% by weight, based on the total weight of the composition. Some In embodiments, the total amount of anhydrous liquid carrier in the composition is It is approximately 20-50% by weight, based on weight. In some embodiments, the composition The total amount of anhydrous liquid carrier is by weight based on the total weight of the composition. It is approximately 35-45%. In some embodiments, the total amount of anhydrous liquid carrier in the composition is The amount is approximately 35-40% by weight, based on the total weight of the composition. Some In embodiments, the total amount of anhydrous liquid carrier in the composition is It is approximately 38.21-39% by weight, based on weight. In some regulations, the total amount of anhydrous liquid carrier in the composition, based on the total weight of the composition It is approximately 39% by weight. In some embodiments, the anhydrous liquid carrier in the composition is The total amount is approximately 35-36% by weight, based on the total weight of the composition.

In some embodiments, the total amount of anhydrous liquid carrier in the composition is It is approximately 35% by weight, based on weight. In some embodiments, the composition The total amount of anhydrous liquid carrier is by weight based on the total weight of the composition. It is approximately 34.65-35.45%. In some embodiments, the total amount of anhydrous liquid carrier in the composition is The amount is approximately 35.45% by weight, based on the total weight of the composition.

In some embodiments, the non-aqueous liquid carrier includes at least one aromatic hydrocarbon. Contains. In some embodiments, the nonaqueous liquid carrier is an aromatic It is hydrocarbon. In some embodiments, the aromatic hydrocarbon is naphthalene. Some In embodiments, the aromatic hydrocarbon is solvent naphtha aromatic heavy 200. Some In some embodiments, the aromatic hydrocarbon is SolvessoTM 200 (made by Exxon Mobil is sold). In some embodiments, the aromatic hydrocarbon is solvent naphtha aromatic 150.

In some embodiments, the aromatic hydrocarbon is SolvessoTM 150 (made by Exxon Mobil is sold). In some embodiments, the aromatic hydrocarbon is the solvent naphtha aromatic It is 100. In some embodiments, the aromatic hydrocarbon is SolvessoTM 100 (Exxon Mobil (sold by). In some embodiments, the aromatic hydrocarbon is CAS No. 64742- In some embodiments, the amount of aromatic hydrocarbons in the composition is Approximately 0% by weight, based on weight, is I-60. In some embodiments, the composition The amount of aromatic hydrocarbons by weight is approximately based on the total weight of the composition. It is approximately 1-20% by weight based on the total weight. In some regulations, The amount of aromatic hydrocarbons in the composition is based on the total weight of the composition It is approximately 10-15% by weight. In some embodiments, the aromatic hydrocarbon in the composition The amount is approximately 11-12% by weight based on the total weight of the composition. Some In embodiments, the amount of aromatic hydrocarbons in the composition depends on the total weight of the composition. It is approximately 11% by weight based on In some embodiments, aromatics in the composition The amount of hydrocarbons by weight is approximately based on the total weight of the composition. It is approximately 12% by weight based on its total weight. In some regulations, The amount of aromatic hydrocarbons in the composition is based on the total weight of the composition In some embodiments, the nonaqueous liquid carrier includes at least one alkyl amide. Some In embodiments, the nonaqueous liquid carrier is an alkyl amide. In some embodiments, aqueous The non-carrier is a decanamide optionally substituted with at least one alkyl. Some In embodiments, the nonaqueous carrier is a carrier optionally substituted with two alkyls. decanamide. In some embodiments, the alkyl amide is N,N-dimethyl decanamide. N,N-dimethyl decanamide, CAS No. It has 14433-76-2. N,N-dimethyl in some embodiments decanamide is Hallomid® M-10 (sold by Stepan). In some regulations, The nonaqueous carrier is an octanamide optionally substituted with at least one alkyl.

In some embodiments, the nonaqueous carrier is optionally substituted with two alkyl It is an octanamide. In some embodiments, the nonaqueous carrier is N,N-dimethyl-octanamide.

In some embodiments, the non-aqueous carrier is N,N-dimethyl-octanamide and N,N-dimethyl. It is a mixture of decanamide.

Alkyl amide, preferably octanamide and/or decanamide, as non-aqueous carrier. The use of the amide group of the anhydrous carrier pyrazole-carboxamide antifungal (e.g. fluxapyroxad) and has crystals in the composition. It stabilizes the pyrazole-carboxamide antifungal solution since it inhibits its growth. It does.

In some embodiments, the amount of alkyl amide in the composition is based on the total weight of the composition. It is approximately 0.1-30% by weight. In some embodiments, the amount of alkyl amide in the composition, approximately 0.1-20% by weight based on the total weight of the composition. Some In embodiments, the amount of alkyl amide in the composition is determined based on the total weight of the composition. It is approximately 0.1-10% by weight. In some embodiments, the amount of alkyl amide in the composition, approximately 1-5% by weight based on the total weight of the composition. In some regulations, The amount of alkyl amide in the composition is approximately It is approximately 3-4% by weight based on In some embodiments, the alkyl amide in the composition The amount is approximately 2.81% by weight, based on the total weight of the composition. Some In embodiments, the amount of alkyl amide in the composition is determined based on the total weight of the composition. It is approximately 3.15% by weight.

In some embodiments, the nonaqueous liquid carrier comprises at least one alkyl ester of the vegetable oil. Contains. In some embodiments, the non-aqueous liquid carrier is an alkyl base of the vegetable oil. is the ester. In some embodiments, the alkyl ester of vegetable oil is an alkyl ester of soybean oil. is the ester. In some embodiments, the alkyl ester of vegetable oil is a methyl ester of soybean oil. is the ester. In some embodiments, the methyl ester of soybean oil, CAS No. to 67784-62-9 has. In some embodiments, the methyl ester of soybean oil, methylated soybean oil bean oil (sold by Cargill).

In some embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 0.1-50% by weight, based on weight. In some embodiments, the composition amount of alkyl ester of the vegetable oil by weight based on the total weight of the composition It is approximately 1-40%. In some embodiments, the amount of alkyl ester of the vegetable oil in the composition, approximately 1-30% by weight based on the total weight of the composition. Some In embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 5-30% by weight, based on weight. In some embodiments, the composition amount of alkyl ester of the vegetable oil by weight based on the total weight of the composition It is approximately 10-20%. In some embodiments, the amount of alkyl ester of the vegetable oil in the composition, approximately 10-15% by weight based on the total weight of the composition. Some In embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 20-30% by weight, based on weight. In some embodiments, the composition amount of alkyl ester of the vegetable oil by weight based on the total weight of the composition It is approximately 20-25%. In some embodiments, the amount of alkyl ester of the vegetable oil in the composition, approximately 13-14% by weight based on the total weight of the composition. Some In embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 13% by weight, based on weight. In some embodiments, the composition amount of alkyl ester of the vegetable oil by weight based on the total weight of the composition It is approximately 12.57-13.37%. In some embodiments, the alkyl ester of the vegetable oil in the composition The amount is approximately 13.37% by weight, based on the total weight of the composition. Some In embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 24-25% by weight, based on weight. In some embodiments, the composition amount of alkyl ester of the vegetable oil by weight based on the total weight of the composition It is approximately 23.5-24.04%. In some embodiments, the alkyl ester of the vegetable oil in the composition The amount is approximately 24% by weight, based on the total weight of the composition. Some In embodiments, the amount of alkyl ester of the vegetable oil in the composition is It is approximately 24.04% by weight based on its weight.

In some embodiments, the nonaqueous carrier contains at least one alcohol. Some In embodiments, the nonaqueous liquid carrier is an alcohol. In some embodiments, the alcohol is 2-ethyl is hexanol. 2-ethyl hexanol, CAS No. He has 104-76-7. In some embodiments, 2-ethyl hexanol is sold by Elekeiroz. Tebuconazole, especially high In compositions containing tebuconazole in high concentration, there is a viscous layer at the bottom of the package. It has been observed that this may occur. 2-ethyl hexanol has good polarity and low viscosity.

The use of 2-ethyl hexanol in the composition prevents the formation of a viscous layer.

In some embodiments, the amount of alcohol in the composition is based on the total weight of the composition. It is approximately 0.1-30% by weight. In some embodiments, the amount of alcohol in the composition It is approximately 1-20% by weight based on the total weight. In some regulations, The amount of alcohol in the composition is approximately 1% by weight, based on the total weight of the composition. 'Stop. In some embodiments, the amount of alcohol in the composition is based on the total weight of the composition. It is approximately 5-10% by weight. In some embodiments, the amount of alcohol in the composition, approximately 8-9% by weight based on the total weight of the composition. Some In embodiments, the amount of alcohol in the composition is based on the total weight of the composition. It is approximately 8.03% by weight.

In some embodiments, the composition includes at least two nonaqueous liquid carriers. Some In embodiments, the composition includes at least three nonaqueous liquid carriers. Some In embodiments, the composition includes three nonaqueous liquid carriers. In some regulations, The composition includes four nonaqueous liquid carriers.

In some embodiments, the nonaqueous liquid carrier is an aromatic hydrocarbon, an alkyl amide and a vegetable oil alkyl ester.

In some embodiments, the nonaqueous liquid carrier is the solvent naphtha aromatic heavy 200,N,N- It is a combination of dimethyl decanamide and methyl ester of soybean oil.

In some embodiments, the nonaqueous liquid carrier is an aromatic hydrocarbon, an alkyl amide, It is a combination of a vegetable oil alkyl ester and an alcohol.

In some embodiments, the non-aqueous liquid carrier solvent naphtha aromatic heavy 200,N,N- dimethyl decanamide, a methyl ester of soybean oil and a combination of 2-ethyl hexanol It is a combination.

In some embodiments, the nonaqueous liquid carrier is an aromatic hydrocarbon and an alkyl carrier. It is a combination of amide. A non-8qu liquid carrier such as SolvessoTM a combination of aromatic hydrocarbon and an alkyl amide such as a decanamide, pyrazole- solubility of carboxamide antifungal and triazole antifungal It provides.

In some embodiments, the nonaqueous liquid carrier is an aromatic hydrocarbon, an alkyl amide. and an alcohol. In some embodiments, non-aqueous liquid The carrier is (i) a solvent naphtha, (ii) N,N-dimethyl-octanamide, N,N-dimethyl decanamide or a mixture thereof; and (iii) a combination of 2-ethyl hexanol.

In some embodiments, the composition includes at least one excipient. In some regulations The auxiliary is inside the liquid carrier.

Auxiliary, vegetable oils, e.g. soya methyl ester, soya ethyl ester, rapeseed oil methyl ester or alkyl esters of vegetable oils such as rapeseed oil ethyl ester, for example polyoxyethylene (16) sorbitan monolaurate (TweenTM 24), polyoxyethylene (20) sorbitan monolaurate (TweenTM 20; Alkamuls® PSML-ZO), polyoxyethylene (4) sorbitan monolaurate (TweenTM 21), polyoxyethylene (8) sorbitan monolaurate (TweenT'V' 22), polyoxyethylene (12) sorbitan monolaurate (TweenT'VI 23), sorbitan monolaurate (Alkamuls® S/20, Glycomul® LK, Glycomul® LC, Span® 20) alkoxylated sorbitan esters, such as sorbitan monolaurate alkoxylates, polyoxyethylene (20) sorbitan monostearate alkoxylates, such as polyoxyethylene (20) sorbitan monostearate (Tween TM 60), polyoxyethylene (4) sorbitan monostearate (TweenTM 61), sorbitan monostearate (Alkamuls® 8190, Glycomul® S, Span® 60), e.g. polyoxyethylene (20) sorbitan monooleate (TweenTM 80, Emulgin® SMO 20, T-Maz® 80, Agnique® SMO 20U), polyoxyethylene (5) sorbitan monooleate (TweenT'V' 81), sorbitan monooleate (Alkamuls® 8/80, sorbitan monooleate alkoxylates such as Span® 80) and combinations thereof may contain. He is not limited by these.

In some embodiments, the adjuvant contains tall oil fatty acids (TOFA) and/or soy methyl ester. and/or sorbitan monolaurate alkoxylates such as polyoxyethylene (16) sorbitan monolaurate.

In some embodiments, the adjuvant is a sorbitan monolaurate alkoxylate. In some regulations The adjuvant is polyoxyethylene (16) sorbitan monolaurate. Help with some arrangements, Tween“VI is 24 (sold by Croda).

In some embodiments, the amount of auxiliary in the composition is determined based on the total weight of the composition. It is approximately 0.1-80%. In some embodiments, the amount of auxiliary in the composition It is approximately 1-20% by weight based on the total weight. In some regulations The amount of auxiliary in the composition is approximately based on the total weight of the composition. It is approximately 11-12% by weight based on In some embodiments, the excipient in the composition The amount is approximately 12-13% by weight, based on the total weight of the composition. Some In embodiments, the amount of auxiliary in the composition is determined based on the total weight of the composition. It is approximately 12% by weight. In some embodiments, the amount of excipient in the composition It is approximately 11.81% based on its total weight. In some embodiments, the composition The amount of auxiliary is approximately 12.05% based on the total weight of the composition.

In some embodiments, the antifungal oil liquid composition also includes at least one surfactant. Contains substance. Surfactant, alkyl sulfonates, alkyl-like sulfonates, alkyl aryl sulfonates, alkylphenolalkoxylates, tristyrylphenol ethoxylates, natural or synthetic fatty acids ethoxylate alcohols, natural or synthetic fatty acid alkoxylates, natural or synthetic fatty acid alkoxylates alcohols alkoxylates, alkoxylated alcohols (such as n-butyl alcohol poly glycol ether), block copolymers (ethylene oxide-propylene oxide block copolymers and ethylene oxide-butylene oxide block copolymers etc.) or combinations thereof, but are not limited to them.

In some embodiments, surfactant, tristyrylphenol ethoxylates, alkyl benzene sulfonates and their salts, ethylene oxide-propylene oxide block copolymers and any thereof is selected from the group consisting of combinations.

In some embodiments, the composition includes at least two surfactants. Some In embodiments, the composition includes at least three surfactants. In some regulations, The composition contains three surfactants.

In some embodiments, the total amount of surfactant in the composition is It is approximately 0.1-40% by weight, based on weight. In some embodiments, the composition the total amount is approximately 1-40% by weight based on the total weight of the composition. Some In embodiments, the total amount in the composition is based on the total weight of the composition. It is approximately 1-25% by weight. In some embodiments, the total amount in the composition It is approximately 1-15% by weight based on the total weight. In some regulations, The total amount in the composition is approximately 5% by weight based on the total weight of the composition. 'truck. In some embodiments, the total amount in the composition is based on the total weight of the composition. It is approximately 7-10% by weight. In some embodiments, the total amount in the composition, approximately 8-9% by weight based on the total weight of the composition. Some In embodiments, the total amount in the composition is based on the total weight of the composition. It is approximately 9-12% by weight. In some embodiments, the total amount in the composition It is approximately 10-11% by weight based on the total weight. In some regulations, the total amount in the composition is approximately by weight based on the total weight of the composition It is approximately 10% by weight based on In some embodiments, the total amount in the composition, approximately 8.69% by weight based on the total weight of the composition. Some In embodiments, the total amount in the composition is based on the total weight of the composition. In some embodiments, the composition includes a tristyrylphenol ethoxylate. In some regulations tristyrylphenol ethoxylate is 16 EO with tristyrylphenol ethoxylate. Tristyrylphenol ethoxylated 16 EO, CAS No. It has 99734-09-05. In some embodiments, tristyrylphenol ethoxylate, Surfom® CE It is 1299 (sold by Oxiteno).

In some embodiments, the amount of tristyrylphenol ethoxylate in the composition depends on the total weight of the composition. It is approximately 0.1-20% by weight based on In some embodiments, tristyrylphenol in the composition The amount of ethoxylate is approximately 0.5-10% by weight based on the total weight of the composition.

In some embodiments, the amount of tristyrylphenol ethoxylate in the composition depends on the total weight of the composition. It is approximately 0.5-5% by weight based on In some embodiments, tristyrylphenol in the composition The amount of ethoxylate is approximately 1 - 2% by weight, based on the total weight of the composition. Some In embodiments, the amount of tristyrylphenol ethoxylate in the composition depends on the total weight of the composition. It is approximately 1.69% by weight based on In some embodiments, tristyrylphenol in the composition The amount of ethoxylate is approximately 1.65% by weight, based on the total weight of the composition.

In some embodiments, the composition includes an alkyl benzene sulfonate or a salt thereof.

In some embodiments, the alkyl benzene sulfonate is docecylbenzene sulfonate. Some In embodiments, the alkyl benzene sulfonate salt is an alkyl benzene sulfonate calcium salt.

In some embodiments, the alkyl benzene sulfonate salt is the dooesylbenzene sulfonate calcium salt.

Docesylbenzene sulfonate calcium salt, CAS No. It has 28264-06-2. Some In embodiments, the docelbenzene sulfonate calcium salt is Rhodacal® GOIBE (Solvay (sold by).

In some embodiments, the amount of alkyl benzene sulfonate or its salt in the composition, approximately 0.1-30% by weight based on the total weight of the composition. Some In embodiments, the amount of alkyl benzene sulfonate or its salt in the composition It is approximately 1-20% by weight based on the total weight. In some regulations, The amount of alkyl benzene sulfonate or its salt in the composition depends on the total weight of the composition. It is approximately 1-10% by weight based on In some embodiments, the alkyl benzene in the composition The amount of sulfonate or its salt by weight based on the total weight of the composition It is approximately 5-8%. In some embodiments, the composition contains alkyl benzene sulfonate or thereof. The amount of salt is approximately G-T% by weight, based on the total weight of the composition. Some In embodiments, the amount of alkyl benzene sulfonate or its salt in the composition It is approximately 6.83% by weight based on its total weight. In some regulations, The amount of alkyl benzene sulfonate or its salt in the composition depends on the total weight of the composition. It is approximately 6.69% by weight based on

In some embodiments, the composition includes an ethylene oxide-propylene oxide block copolymer.

In some embodiments, the ethylene oxide-propylene oxide block copolymer, CAS No. to 9038-95-3 has. In some embodiments, the ethylene oxide-propylene oxide block copolymer, AtlasTM 5002 L It is LQ (CQ) (sold by Croda). In some embodiments, ethylene oxide-propylene oxide block copolymer, CAS No. It has 9003-11-6. In some embodiments, ethylene oxide- The propylene oxide block copolymer is Symperonic PE/F 68FL (sold by Croda).

In some embodiments, the amount of ethylene oxide-propylene oxide block copolymer in the composition, approximately 0.1-15% by weight based on the total weight of the composition. Some In embodiments, the amount of ethylene oxide-propylene oxide block copolymer in the composition It is approximately 0.1-10% by weight based on the total weight. In some regulations, The amount of ethylene oxide-propylene oxide block copolymer in the composition depends on the total weight of the composition. It is approximately 0.1-5% by weight based on In some embodiments, ethylene oxide in the composition The amount of propylene oxide block copolymer by weight based on the total weight of the composition It is approximately 0.1-2%. In some embodiments, the ethylene oxide-propylene oxide block in the composition The amount of copolymer is approximately 0.1-1% by weight, based on the total weight of the composition.

In some embodiments, the amount of ethylene oxide-propylene oxide block copolymer in the composition, It is approximately 1-2% by weight based on the total weight of the composition. In some regulations, The amount of ethylene oxide-propylene oxide block copolymer in the composition depends on the total weight of the composition. It is approximately 0.1-0.5% by weight based on In some embodiments, the ethylene in the composition amount of oxide-prcylene oxide block copolymer based on the total weight of the composition It is approximately 1.5-2% by weight. In some embodiments, the ethylene oxide-propylene oxide in the composition The amount of block copolymer is approximately 0.3% by weight based on the total weight of the composition. is 0.4. In some embodiments, the amount of ethylene oxide-propylene oxide block copolymer in the composition, approximately 0.35% by weight, based on the total weight of the composition. Some In embodiments, the amount of ethylene oxide-propylene oxide block copolymer in the composition It is approximately 1.61% by weight based on its total weight.

In some embodiments, the compound is a tristyrylphenol ethoxylate, an alkyl benzene sulfonate, or It contains a salt and an ethylene oxide-propylene oxide block copolymer.

In some embodiments, the compound includes tristyrylphenol ethoxylated 16 EO, docecylbenzene sulfonate It contains calcium salt and an ethylene oxide-propylene oxide block copolymer.

Available to increase the stability, density and viscosity of the described compositions compounds include adhesives, neutralizers, thickeners, binders, sequestrates, biocides, stabilizers, suspension aids, protective buffers, antioxidants, Other ingredients such as anti-foaming agents or anti-freezing agents may also be used can be added.

In some embodiments, the composition includes an antifoam agent. Some In embodiments, the antifoam agent is polydimethylsiloxane. In some regulations polydimethylsiloxane, CAS No. It has 63148-62-9. In some regulations polydimethylsiloxane is Silcolapse® 500 (sold by Elkem).

In some embodiments, the amount of antifoam agent in the composition is greater than the total amount of the composition. It is approximately 0.01-10% by weight, based on weight. In some embodiments, the composition amount of antifoam agent by weight based on the total weight of the composition It is approximately 0.01-5%. In some embodiments, the amount of antifoam agent in the composition, approximately 0.01-1% by weight based on the total weight of the composition. Some In embodiments, the amount of antifoam agent in the composition depends on the total weight of the composition. It is approximately 0.01-0.1% by weight based on In some embodiments, the foam in the composition The amount of inhibitory agent by weight is approximately based on the total weight of the composition. approximately 0.04% by weight, based on the total weight of the composition.

In some embodiments, the composition includes a suspension aid. Some In embodiments, the suspension aid is silica, fumed silica, silicic anhydride, silicon dioxide. and/or amorphous silicon dioxide. In some embodiments, the suspension aid is smoked It is silica. In some embodiments, the suspension aid is CAS No. It has 112945-52-5.

In some embodiments, the suspension aid is CARB-O-SIL® M5 (Cabot Corporation (sold by). Addition of a suspension aid, preferably silica, It reduces clumping in the composition.

In some embodiments, the amount of suspension aid in the composition is greater than the total amount of the composition. It is approximately 0.01-20% by weight, based on weight. In some embodiments, the composition The amount of suspension aid is approximately based on the total weight of the composition. It is approximately 0.1-10% by weight based on the total weight. In some regulations, amount of suspension aid in the composition based on the total weight of the composition It is approximately 0.1-5% by weight. In some embodiments, the suspension aid in the composition The amount is approximately 0.1-1% by weight, based on the total weight of the composition. Some In embodiments, the amount of suspension aid in the composition depends on the total weight of the composition. It is approximately 0.8% by weight based on

In some embodiments, the composition does not include a suspension aid. Some In embodiments, the composition does not contain fumed silica.

In some embodiments, the composition includes a stabilizer. In some regulations, the stabilizer is zinc oxide (CAS No. 1314-13-2). In some embodiments, the stabilizer Sold by Produquimica. Many of the compounds described herein are commercially available. It is preferred that it is compatible with the glyphosate formulation. Amphoteric surfactant This compatibility of substances (such as zinc oxide) or zwitterionic surfactants It has been discovered that it can increase Additionally, the use of zinc oxide in the composition increases the viscosity of the composition. It has the advantage of increasing compatibility with glyphosate formulations without increasing Some In embodiments, the viscosity of the composition is between 500-2500 cp (speed 6, spindle 2).

In some embodiments, the viscosity of the composition is between 500-2000 cp (speed 6, mil 2). Some In embodiments, the viscosity of the composition is between 800-1500 op (speed 6, mil 2).

In some embodiments, the amount of stabilizer in the composition is based on the total weight of the composition. It is approximately 0.1-10% by weight. In some embodiments, the stabilizer in the composition The amount is approximately 0.1-5% by weight, based on the total weight of the composition. Some In embodiments, the amount of stabilizer in the composition is based on the total weight of the composition. It is approximately 1-2% by weight. In some embodiments, the amount of stabilizer in the composition, approximately 1.5% by weight, based on the total weight of the composition. In some regulations, The amount of stabilizer in the composition is approximately based on the total weight of the composition. It is approximately 1.6% by weight, based on weight. In some embodiments, the composition The amount of stabilizer is approximately 1.61% by weight based on the total weight of the composition.

In some embodiments, the composition has a pH of 5-9. In some embodiments, the composition is 5.5- It has a pH of 8.5.

In some embodiments, the density of the composition at 20°C is approximately 1-1.5 g/cm3. Some In embodiments, the density of the composition at 20°C is approximately 1.245 g/cm3. Some In embodiments, the density of the composition at 20°C is approximately 1.2? is g/cm3.

The present invention also provides an antifungal oil liquid composition comprising: (ii) 2-3% prothioconazole by weight, (iii) 1-2% fluxapyroxad by weight, 2.5-3.5% by weight N,N-dimethyl decanamide, 1-2% by weight tristyrylphenol ethoxylated 16 EO, 0.1-1% by weight ethylene oxide-propylene oxide block copolymer, 10-13% by weight sorbitan monolaurate ethoxylated, 6-7% by weight dodecylbenzene sulfonate calcium salt, 0.01-0.1% by weight polydimethylsiloxane, 22-26% methyl ester by weight of soybean oil, 10-13% by weight solvent naphtha aromatic heavy 200 and 1-2% zinc oxide by weight.

The present invention also provides an antifungal oil liquid composition comprising: 33-36% mancoseb by weight, 2-3% prothioconazole by weight, 2.5-3.5% by weight N,N-dimethyl decanamide, 1-2% by weight tristyrylphenol ethoxylated 16 EC, 0.1-1% by weight ethylene oxide-propylene oxide block copolymer, 10-13% by weight sorbitan monolaurate ethoxylated, 6-7% by weight dodecylbenzene sulfonate calcium salt, 0.01-0.1% by weight polydimethylsiloxane, 22-26% methyl ester by weight of soybean oil, (xi) 10-13% by weight solvent naphtha aromatic heavy 200, (xii) 1-2% by weight zinc oxide and (xiii) 0-1% silica by weight.

The present invention also provides an antifungal oil liquid composition comprising: (i) 33-36% mancoseb by weight, (ii) 3-4% tebuconazole by weight, (iii) 1-2% fluxapyroxad by weight, (iv) 2-3% by weight N,N-dimethyl decanamide, (v) 11-13 wt% sorbitan monolaurate ethoxylated, (vi) 1-2 wt% tristyrylphenol ethoxylated 16 EC, (vii) 6-7% by weight dodecylbenzene sulfonate calcium salt, (viii) 0.01-0.1% by weight polydimethylsiloxane, (ix) 11-15% by weight methyl ester of soybean oil, (x) 10-13% by weight solvent naphtha aromatic heavy 200, (xi) 1-2% by weight ethylene oxide-propylene oxide block copolymer, (xii) 7.5-8.5% by weight 1-ethyl hexanol and (xiii) 1-2% zinc oxide by weight.

The present invention also provides an antifungal oil liquid composition comprising: (il) 3-4% tebuconazole by weight, 2-3% by weight N,N-dimethyl decanamide, 11-13 wt% sorbitan monolaurate ethoxylated, 1-2% by weight tristyrylphenol ethoxylated 16 EO, 6-7% by weight dodecylbenzene sulfonate calcium salt, 0.01-0.1% by weight polydimethylsiloxane, 11-15% methyl ester by weight of soybean oil, 10-13% by weight solvent naphtha aromatic heavy 200, 1-2% by weight ethylene oxide-propylene oxide block copolymer, 7.5-8.5% by weight 1-ethyl hexanol, 1-2% zinc oxide by weight and 0-1% silica by weight.

The present invention also provides an antifungal oil liquid composition comprising: 34.64% mancoseb by weight, 2.48% prothioconazole by weight, 1.77% fluxapyroxad by weight, 3.15% by weight N,N-dimethyl decanamidine, 1.65 wt% tristyrylphenol ethoxylated 16 EC, 0.35% by weight ethylene oxide-propylene oxide block copolymer, 11.81 wt% sorbitan monolaurate ethoxylated, (viii) 6.69% by weight dodecylbenzene sulfonate calcium salt, (ix) 0.04% by weight polydimethylsiloxane, (x) 24.04% by weight methyl ester of soybean oil, (xi) 11.81% by weight solvent naphtha aromatic heavy 200 and (xii) 1.57 wt% zinc oxide.

The present invention also provides an antifungal oil liquid composition comprising: (i) 34.64% mancoseb by weight, (ii) 2.48% prothioconazole by weight, (iii) 1.77% fluxapyroxad by weight, (iv) 3.15% by weight N,N-dimethyl decanamidine, (v) 1.65 wt% tristyrylphenol ethoxylated 16 EC, (vi) 0.35 wt% ethylene oxide-propylene oxide block copolymer, (vii) 11.81 wt% sorbitan monolaurate ethoxylated, (viii) 6.69% by weight dodecylbenzene sulfonate calcium salt, (ix) 0.04% by weight polydimethylsiloxane, (x) 23.25-24.04% by weight methyl ester of soybean oil, (xi) 11.81% by weight solvent naphtha aromatic heavy 200, (xii) 1.57% by weight zinc oxide and (xiii) 0-0.79% silica by weight.

The present invention also provides an antifungal oil liquid composition comprising: 35.34% mancoseb by weight, 357% tebuconazole by weight, 1.81% fluxapyroxad by weight, 2.81% by weight N,N-dimethyl decanamide, 12.05 wt% sorbitan monolaurate ethoxylated, 1.69% by weight tristyrylphenol ethoxylated 16 EC, 6.83% by weight dodecylbenzene sulfonate calcium salt, 0.04% by weight polydimethylsiloxane, 13.37% methyl ester by weight of soybean oil, 11.24% by weight solvent naphtha aromatic heavy 200, 1.61% by weight ethylene oxide-propylene oxide block copolymer, 8.03% by weight 1-ethyl hexanol and 1.61% zinc oxide by weight.

The present invention also provides an antifungal oil liquid composition comprising: 35.34% mancoseb by weight, 3.57% tebuconazole by weight, 1.81% fluxapyroxad by weight, 2.81% by weight N,N-dimethyl decanamide, 12.05 wt% sorbitan monolaurate ethoxylated, 1.69% by weight tristyrylphenol ethoxylated 16 EC, (vii) 6.83% by weight dodecylbenzene sulfonate calcium salt, (viii) 0.04% by weight polydimethylsiloxane, (ix) 12.57-13.37% by weight soybean oil methyl ester, (x) 11.24% by weight solvent naphtha aromatic heavy 200, (xi) 1.61% by weight ethylene oxide-propylene oxide block copolymer, (xii) 8.03% by weight 1-ethyl hexanol, (xiii) 1.61% by weight zinc oxide and In some embodiments, the composition is chemically stable.

In some embodiments, after 2 weeks of storage at room temperature, the composition Dithiocarbamate antifungal has less than 35% degradation. In some regulations, After 2 weeks of storage at 54°C, the presence of dithiocarbamate antifungal in the composition Less than 35% degradation of dithiocarbamate antifungal in the composition after storage has. In some embodiments, after 8 weeks of storage at 40°C, the composition Dithiocarbamate antifungal has less than 35% degradation. In some regulations, After 1 week of storage at 0°C, the presence of dithiocarbamate antifungal in the composition There is then less than 35% degradation of the dithiocarbamate antifungal in the composition.

In some embodiments, after 2 weeks of storage at room temperature, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal has. In some embodiments, after 2 weeks of storage at 54°C, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal has. In some embodiments, after 8 weeks of storage at room temperature, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal has. In some embodiments, after 8 weeks of storage at 40°C, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal has. In some embodiments, after 1 week of storage at 0°C, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal has. In some embodiments, after 1 week of storage at -10°C, the composition less than 30%, less than 25%, less than 20%, less than 15%, of dithiocarbamate antifungal In some embodiments, the triazole remains in the composition after 2 weeks of storage at room temperature. The antifungal has less than 20% degradation. In some embodiments, 2 at 54°C Less than 20% degradation of the triazole antifungal in the composition after weeks of storage has. In some embodiments, after 8 weeks of storage at room temperature, the composition The triazole antifungal has less than 10% degradation. In some embodiments, 8 at 40°C Less than 20% degradation of the triazole antifungal in the composition after weeks of storage has. In some embodiments, the triazole remains in the composition after 1 week of storage at 0°C. The antifungal has less than 20% degradation. In some embodiments, 1 at -10°C Less than 20% degradation of the triazole antifungal in the composition after weeks of storage In some embodiments, the triazole remains in the composition after 2 weeks of storage at room temperature. has. In some embodiments, the triazole remains in the composition after 2 weeks of storage at 54°C. has. In some embodiments, after 8 weeks of storage at room temperature, the composition has. In some embodiments, triazole remains in the composition after 8 weeks of storage at 40°C. has. In some embodiments, triazole is present in the composition after 1 week of storage at 0°C. has. In some embodiments, the triazole remains in the composition after 1 week of storage at -10°C. In some embodiments, after 2 weeks of storage at room temperature, the composition contains pyrazole- Carboxamide antifungal has less than 15% degradation. In some regulations, After 2 weeks of storage at 54°C, the presence of pyrazole-carboxamide antifungal in the composition less than 15% of pyrazole-carboxamide antifungal in the composition after storage There is degradation. In some embodiments, after 8 weeks of storage at 40°C, the composition The pyrazole-carboxamide antifungal has less than 15% degradation. Some In embodiments, pyrazole-carboxamide is present in the composition after 1 week of storage at 0°C. The antifungal has less than 15% degradation. In some embodiments, 1 at -10°C less than 15% of the pyrazole-carboxamide inhibitor in the composition after weeks of storage There is degradation.

In some embodiments, after 2 weeks of storage at room temperature, the composition contains pyrazole- 12.5%, less than 10%, less than 7.5%, less than 5%, less than 4%, of carboxamide antifungal After 2 weeks of storage, the presence of pyrazole-carboxamide antifungal in the composition less than 12.5% of pyrazole-carboxamide antifungal in the composition after storage, There is degradation. In some embodiments, after 8 weeks of storage at 40°C, the composition less than 12.5%, less than 10%, less than 7.5%, less than 5% of pyrazole-carboxamide antifungal It has less than 4%, less than 3%, less than 2% or less than 1% degradation. Some In embodiments, pyrazole-carboxamide is present in the composition after 1 week of storage at 100 °C. It has little, less than 2% or less than 1% degradation. In some embodiments, 1 at -10°C After one week of storage, the pyrazole-carboxamide antifungal content in the composition was less than 12.5%. It has little degradation.

In some embodiments, the composition is physically stable.

In some embodiments, less than 30% in composition after 2 weeks of storage at room temperature. There is little or less than 1% phase separation. In some embodiments, 2 weeks at 54°C less than 30%, less than 25%, less than 20%, less than 15%, less than 10% in composition after storage There is less than 7.5%, less than 5%, less than 2.5% or less than 1% phase separation. Some In embodiments, less than 30% in composition after 8 weeks of storage at room temperature, or there is less than 1% phase separation. In some embodiments, 8 weeks of storage at 40°C There is less than 5%, less than 2.5% or less than 1% phase separation. In some embodiments, at 0°C Less than 30%, less than 25%, less than 20%, less than 15% in the composition after 1 week of storage There is less than 10%, less than 7.5%, less than 5%, less than 2.5% or less than 1% phase separation.

In some embodiments, less than 30% in the composition after 1 week of storage at -10°C, or there is less than 1% phase separation.

In some embodiments, 4% phase in the composition after 2 weeks of storage at room temperature. There is a distinction. In some embodiments, after 2 weeks of storage at room temperature There is a 2% phase separation in the composition. In some embodiments, 2 weeks of storage at 54°C Then there is a 4% phase separation in the composition. In some embodiments, 8 weeks at room temperature There is a 25% phase separation in the composition after storage. In some arrangements, the room There is a 4% phase separation in the composition after 8 weeks of storage at Some In embodiments, there is 8% phase separation in the composition after 8 weeks of storage at 40°C.

In some embodiments, 4% phase separation in composition after 8 weeks of storage at 40°C has. In some embodiments, phase separation in the composition occurs after 1 week of storage at 0°C. There is no. In some embodiments, 2% phase in the composition after 1 week of storage at 0°C. There is a distinction. In some embodiments, the phase appears in the composition after 1 week of storage at 40°C. There is no distinction. In some embodiments, after 1 week of storage at -10°C, the composition In some embodiments, 250 mL of composition after 2 weeks of storage at room temperature. There is less than 2 mL, less than 1 mL, or less than 0.5 mL of residue per head. In some regulations, After 2 weeks of storage at 54°C, less than 2 mL, not less than 1 mL per 250 mL of the composition There is little or less than 0.5 mL of residue. In some embodiments, 8 weeks at room temperature less than 2 mL, less than 1 mL, or 0.5 per 250 mL of composition after storage There is less than mL of residue. In some embodiments, after 8 weeks of storage at 40°C, 250 There is less than 2 mL, less than 1 mL, or less than 0.5 mL of residue per mL of composition.

In some embodiments, 250 mL of the composition after 2 weeks of storage at room temperature There is 0.3 mL of sediment per head. In some embodiments, up to 2 weeks of storage at room temperature then there is 0.15 mL of residue per 250 mL of composition. In some embodiments, 2 at 54°C After weeks of storage there is 0.3 mL of residue per 250 mL of composition. Some In embodiments, 0.15 per 250 mL of the composition after 2 weeks of storage at 54°C. mL of sediment is present. In some embodiments, after 8 weeks of storage at room temperature There is 0.3 mL of residue per 250 mL of the composition. In some embodiments, 8 at room temperature After weeks of storage there is 0.15 mL of residue per 250 mL of composition. Some In embodiments, 0.3 per 250 mL of composition after 8 weeks of storage at 40°C. mL of sediment is present. In some embodiments, after 8 weeks of storage at 40°C the composition There is 0.2 mL of residue per 250 mL.

In some embodiments, the composition is stored in a leak-proof container.

In some embodiments, the composition is used to treat fungal infection of the plant or Iocus. In the preparation, the same amount of each antifungal is mixed with the compositions described herein. It is more effective than applying it in a different way.

In some embodiments, the composition is used to treat fungal infection of the plant or Iocus. In the process, the same amount of each antifungal is used as a tank mixture. It is more effective than applying

In some embodiments, the composition is used to treat fungal infection of the plant or Iocus. is better than applying the same amount of each antifungal separately. is effective.

The compositions disclosed herein are suitable for controlling a wider variety of unwanted pests. It can be used in combination with one or more other pesticides. Other When used in combination with pesticides, the composition described herein Formulated by tank mixing with pesticide(s) or by applying sequentially with other pesticide(s). can be done. In addition, the composition disclosed herein may optionally be used with other pesticides. It can be combined or mixed with its compounds. This pesticide mixture, to control pests in crops and non-crop environments can be used.

Combinations and Mixtures The present invention also (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) a combination comprising an amount of at least one pyrazole-carboxamide antifungal It provides.

The present invention also (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) a combination comprising an amount of at least one pyrazole-carboxamide antifungal It provides, where the combination is effective against fungal infection of a plant or a locus treatment, the same amount of each antifungal should be applied alone. becomes more effective.

The present invention also (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) a combination comprising an amount of at least one pyrazole-carboxamide antifungal It provides, where is the amount of dithiocarbamate antifungal, is the amount of triazole antifungal, and When a quantity of pyrazole-carboxamide antifungal is applied together, a plant or In the treatment of a Iocus against a fungal infection, each antifungal is the same. It is more effective than applying small amounts alone.

The present invention also (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) a combination comprising an amount of at least one pyrazole-carboxamide antifungal It provides, where the amount of dithiocarbamate antifungal is the amount of dithiocarbamate antifungal. Dithiocarbamate fungicide, which is effective as an antifungal when used alone is less than the preventive amount, where is the amount of triazole inhibitor when used alone, less than the antifungal effective amount of triazole antifungal being and/or where is the amount of pyrazole-carboxamide antifungal, pyrazole-carboxamide is the amount of antifungal When the inhibitor is used alone, the pyrazole-carboxamide antifungal It is less than the amount that is effective as a preventive measure.

In some embodiments, the combination includes at least one agrochemically acceptable 3qu Contains non-liquid carrier.

In some embodiments, the combination is a mixture.

In some embodiments, the combination is synergistic.

In some embodiments, the mixture is synergistic.

The combination or mixture can also be used in conjunction with the antifungal oil liquid composition It may contain one or more of the components described above.

The present invention also includes any of the combinations or mixtures disclosed herein. It provides an antifungal composition containing one.

In some embodiments, the antifungal composition is an antifungal oil composition.

In some embodiments, the antifungal composition includes an antifungal oil. is the formulation.

In some embodiments, the combination is diluted in water. In some regulations The mixture is diluted in water. In some embodiments, the antifungal composition is mixed with water. It is diluted in .

Usage Methods The present invention also consists of combinations, mixtures or mixtures disclosed herein. involving the application to the plant or locus of an effective amount of either compound. to treat a plant or a site against fungal infection, thus protecting the plant or provides a method to treat the site for fungal infection.

The present invention also provides treatment of a plant or locus against fungal infection. provides a method for treating the plant or Iokus by applying the following: (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) an amount of at least one pyrazole-carboxamide antifungal The present invention also provides treatment of a plant or locus against fungal infection. provides a method for treating the plant or Iokus by applying the following: (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) an amount of at least one pyrazole-carboxamide antifungal, thus the plant or Iocus is treated against fungal infection, where dithiocarbamate antifungal amount, triazole antifungal amount and pyrazole- When a quantity of carboxamide antifungal is applied together, a plant or a locus In the treatment of fungal infection, use the same amount of each antifungal It is more effective than applying it to the head.

The present invention is also applicable to treating a plant or Iocus against fungal infection. provides a method for treating the plant or Iokus by applying the following: (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal; and (iii) an amount of at least one pyrazole-carboxamide antifungal, so that the plant or where the amount of dithiocarbamate antifungal applied is dithiocarbamate antifungal when used alone is less than the effective amount, The amount of triazole antifungal applied here is the triazole antifungal alone. less than the antifungal effective amount of triazole antifungal when used being and/or amount of pyrazole-carboxamide antifungal applied, pyrazole-carboxamide antifungal When the inhibitor is used alone, the pyrazole-carboxamide antifungal It is less than the preventively effective amount.

In some embodiments, the method is used to control fungal infection of the plant or Iocus. is effective.

In some embodiments, controlling fungal infection involves preventing the plant or locus from being infected. It includes controlling the fungal disease that causes In some embodiments, mushroom control of infection caused by phytopathological fungi in a plant or includes controlling soil disease. In some embodiments, mushroom control of infection, control of fungal attack on the plant or Iocus It includes . Controlling fungal infection in some regulations, It involves reducing fungal infection of the plant or Iocus. Some regulations, control of fungal infection, prevention of diseases caused by phytopathological fungi It includes the treatment of a plant or soil disease.

In some embodiments, the method is used to control fungal infection of the plant or Iocus. is effective.

In some embodiments, protection of the plant or locus against fungal infection or protection of Iokus against fungal attack. In some regulations protection of the plant or Iocus against fungal infection, protection of the plant or Iocus against fungal infection It includes protection against disease. In some embodiments, the plant or locus is fungal protection against infection, prevention of fungal infection of the plant or Iocus Contains.

In some embodiments, the method consists of combinations, mixtures, or An effective amount of either compound is administered to the reproductive material of the plant. includes its implementation. In some embodiments, the method described herein an effective amount of any of the combinations, mixtures or compositions It includes application to the seed and/or seedling of the plant.

In some embodiments, the method consists of combinations, mixtures, or comprising a protective application of any of the compositions. Some In embodiments, the method consists of combinations, mixtures or comprising a therapeutic application of any of the compositions.

In some embodiments, fungal attack refers to fungal attack on the plant, seed or seedling. is controlled by preventing it. In some embodiments, fungal attack on plants, seeds or It is controlled by treating the fungal attack on the seedling.

In some embodiments, antifungals are applied simultaneously.

In some embodiments, antifungals are applied simultaneously.

In some embodiments, antifungals are applied sequentially.

In some embodiments, antifungals are applied separately.

In some embodiments, antifungals are applied together.

In some embodiments, antifungals are applied together as a tank mix.

In some embodiments, antifungals include combinations described herein, It is applied in the form of any of the mixtures or compositions.

In some embodiments, the amount of dithiocarbamate fungicide, the amount of triazole fungicide, and the amount of pyrazole- amount of carboxamide fungicide in combination with any of the compositions described herein. When applied to treat plant or Iocus against fungal infection, each the same amount of antifungal in a form other than the compositions described herein. It is more effective than applying

In some embodiments, the amount of dithiocarbamate fungicide, the amount of triazole fungicide, and amount of pyrazole-carboxamide fungicide, any of the compositions described herein Treatment against fungal infection of the plant or Iocus when applied together in the form of In the process, the same amount of each antifungal is used as a tank mixture. It is more effective than applying

In some embodiments, the amount of dithiocarbamate fungicide, the amount of triazole fungicide, and amount of pyrazole-carboxamide fungicide, any of the compositions described herein Treatment against fungal infection of the plant or locus when applied together in the form of is better than applying the same amount of each antifungal separately. is effective.

In some embodiments, antifungals are applied to a portion of a plant, an area adjacent to a plant, soil in contact with a plant, soil adjacent to a plant, any soil adjacent to a plant in contact with a surface, a plant, seed and/or equipment used in agriculture It is applied to any surface. In some embodiments, antifungals are part of the plant. locus, a locus close to the plant, a locus of fungi, or a locus close to fungi is applied to the locus. In some embodiments, antifungals are used depending on where the plant is grown. It is applied to the soil. In some arrangements, antifungals are applied to the plant as it is grown. It is applied to the soil.

In some arrangements, fungicides are applied at planting.

In some embodiments, antifungals are applied 1 to 60 days after planting.

In some embodiments, antifungals are applied 1 to 9 months after planting.

In some embodiments, antifungals are applied once during a growing season. is implemented.

In some embodiments, antifungals should be applied at least once during a growing season. is implemented.

In some embodiments, antifungals may be applied two or more times during a growing season. It is applied once.

In some embodiments, antifungals are applied three times during a growing season. is implemented. In some arrangements, applications are made 15 days apart.

In some embodiments, fungicides are applied as a soil application. Some In embodiments, antifungals are applied as a foliar application.

The combinations, mixtures and compositions disclosed herein may be harmful to phytopathogenic fungi. It is suitable for the control of unwanted pests.

Effective application rates of the antifungal compound depend on pesticide type, target pest, weather conditions, and weather conditions. conditions vary depending on various conditions such as the nature of the soil and the type of crop cannot be defined in general. In some embodiments, the antifungal composition It is applied at a rate of approximately 1 to approximately 5 L/ha. In some embodiments, mushroom The preventive composition is applied at a rate of approximately 2 to 3 L/ha. In some regulations, The antifungal composition is applied at a rate of approximately 2 Li'ha. In some regulations, The antifungal composition is applied at a rate of approximately 3 L/ha. In some regulations, The antifungal composition is applied at a rate of approximately 2.25 L/ha. Some In embodiments, the antifungal composition is applied at a rate of approximately 2.5 L/ha.

In some embodiments, the antifungal composition is administered at a rate of approximately 2.75 L/ha. is implemented.

In some embodiments, the pyrazole-carboxamide antifungal is administered at approximately 10 g a.i.lha to It is applied at a rate of approximately 100 g a.i.lha. In some embodiments, pyrazole- carboxamide antifungal, approximately 30 g a.i.lha to approximately 80 g a.i.lha is applied at this rate. In some embodiments, pyrazole-carboxamide antifungal, It is administered at a rate of approximately 50 g a.i.lha to approximately 65 g a.i.lha. Some In embodiments, the pyrazole-carboxamide antifungal is administered at a rate of approximately 51 g a.i.lha. is implemented. In some embodiments, the pyrazole-carboxamide antifungal provides approximately 56 It is applied at the rate of g a.i.lha. In some embodiments, pyrazole-carboxamide mushroom The preventive is applied at a rate of approximately 62 g a.i.Iha.

In some embodiments, triazole antifungal from about 10 g a.i.lha to about 200 g a.i.lha It is applied at a rate between . In some embodiments, triazole antifungal It is administered at a rate of approximately 70 g a.i.lha to approximately 130 g a.i.lha. Some in embodiments, triazole antifungal from about 50 g a.i.lha to about 150 g a.i.lha It is applied at a rate between . In some embodiments, triazole antifungal It is administered at a rate of approximately 70 g a.i.lha to approximately 90 g a.i.lha. Some In embodiments, triazole antifungal from about 100 g a.i.lha to about 130 g a.i.lha It is applied at a rate between . In some embodiments, triazole antifungal It is applied at a rate of approximately 71 g a.i.lha. In some embodiments, triazole fungus The preventive is applied at a rate of approximately 79 g a.i.lha. In some embodiments, triazole The antifungal is applied at a rate of approximately 87 g a.i.lha. In some regulations, The triazole antifungal is applied at a rate of approximately 101 g a.i.i'ha. Some In embodiments, the triazole antifungal is applied at a rate of approximately 111 g a.i.lha.

In some embodiments, the triazole antifungal is administered at a rate of approximately 122 g a.i./ha. is implemented.

In some embodiments, dithiocarbamate antifungal contains about 100 g a.i.lha to about It is implemented at a rate between 2000 and 9 a.i.lha. In some embodiments, dithiocarbamate antifungal at a rate of approximately 500 g a.i.lha to approximately 1500 g a.i.lha is implemented. In some embodiments, dithiocarbamate antifungal contains approximately 900 g It is applied at a rate between a.i.lha and approximately 1200 9 a.i.Iha. Some In embodiments, dithiocarbamate antifungal is administered at a rate of approximately 990 g a.i.lha. is implemented. In some embodiments, dithiocarbamate antifungal is approximately 1100 9 It is applied at the rate of a.i.lha. In some embodiments, dithiocarbamate antifungal It is applied at a rate of approximately 1210 9 a.i.lha.

In some embodiments, the dithiocarbamate is the antifungal mancozeb.

In some embodiments, the triazole antifungal is prothioconazole. In some regulations The triazole antifungal is tebuconazole.

In some embodiments, the pyrazole-carboxamide antifungal is fluxapyroxad.

Methods of use include adding the antifungal composition to a carrier such as water and The final solution containing the inhibitory compound is used to control phytopathogenic fungi in the plant. spray applications or their propagation in crop or non-crop environments. Includes the use of materials. By diluting the antifungal composition in water A suspoemulsion can be formed.

In some embodiments, the combination is diluted in water prior to administration. Some In embodiments, the mixture is diluted in water prior to application. Some In embodiments, the composition is diluted in water prior to application.

In some embodiments, the antifungal composition is dispersed in a carrier such as water per 1000 L of water. It can be diluted in an amount of approximately 1 to 100 L of antifungal composition. Some In embodiments, the composition is administered in a carrier such as water at approximately 1 to 30 L per 1000 L of water. It can be diluted in the amount of antifungal composition. In some embodiments, the composition includes water Approximately 5 to 15 L of antifungal composition per 1000 L of water in a carrier such as It can be diluted in quantity.

The methods of the present invention are suitable for soybeans, cereals, wheat corn, papaya, melon, cocoa. and any crop plant, including but not limited to coffee can be applied. In some embodiments, the plant is a soybean plant. Some In embodiments, the soybean plant belongs to the BONUS variety. Soy in some regulations bean plant belongs to M 5917 IPRO variety.

In some embodiments, phytopathogenic fungi, soybean rust (Phakopsora pachyrhizi), target spot (Corynespora cassiicola), late season diseases (Septoria glycines and Cercospora kikuchii), Northern leaf blight (Exserohilum turcicum), yellow leaf spot (Dreshslera tritici-repentis), Phaeosphaeria leaf spot (Phaeosphaeria maydis), Anthracnose (Colletotrichum gloeosporioides), Cereal smut, Common smut (Ustilago maydis), Head smut (Sphacelotheca reiliana), False smut (Ustilaginoidea virens), Flag smut (Usrocystis agropyri), Loose wheat/barley preparation (Ustilago nuda), Closed soot (Ustilago segetum var. hordei) and Yari loose is (Ustilago avenae), including, but not limited to One or more classes that are not bounded. In some embodiments, phytopathogenic fungi Soybean rust. (Phakopsora pachyrhizi).

The combinations, mixtures and compositions described herein can be used with water and/or fertilizers. can be mixed and used in aircraft spray tanks, backpack spray tanks, cattle dip boats, farm equipment used for ground spraying (e.g. boom to a desired location by any means such as sprayers, hand sprayers) and the like. can be applied. The desired Iocus can be soil, plants and the like.

The combinations, mixtures and compositions described herein are suitable for use in the vegetative growth phase. From V2 (Second trifoliolate - doubly unopened trifoliolate leaf) to reproductive growth stage R8 (Full maturity - 95% of the pods have reached their full mature color) soybeans can be applied.

Combinations of mixtures and compositions, e.g. insecticides, herbicides, fungicides inhibitors, antibacterials, nematicides, mollusc inhibitors, growth regulators, additional plant protection agents such as biological substances, fertilizers or mixtures thereof. may contain. When used in combination with additional plant protection agents, The composition can be formulated with these excipients. It can be mixed or applied sequentially with auxiliary ingredients.

The present invention also provides treatment against fungal infection of a plant or a plant. combinations, mixtures or compositions disclosed herein to It allows anyone to use it.

The present invention also provides treatment against fungal infection of a plant or a plant. combinations, mixtures and mixtures described herein for use in provides any of the combinations.

The present invention also consists of combinations, mixtures or mixtures disclosed herein. provides a package containing any of the combinations.

Preparation Processes The present invention also consists of combinations, mixtures or mixtures disclosed herein. a process for preparing any of the compositions from separate component parts It provides.

The present invention also includes any of the antifungal oil liquid compositions disclosed herein. provides a process for preparing one that includes the following steps: (i) at least one triazole antifungal and at least one pyrazole antifungal to obtain a solution; carboxamide antifungal in at least one non-aqueous liquid carrier. dissolution; (ii) add at least one auxiliary, surfactant solution to the solution in step (i) to obtain the mixture. adding agent, antifoam agent and/or stabilizer; And (iii) add at least one addition to the mixture in step (ii) to obtain the antifungal oil composition. addition of dithiocarbamate antifungal.

In some embodiments, step (i) is performed under agitation. Some In embodiments, step (i) is performed under 300-400 rpm shaking.

In some embodiments, step (i), triazole antifungal, pyrazole-carboxamide antifungal and heating the nonaqueous liquid carrier until a solution is obtained.

In some embodiments, step (i) triazole antifungal until a solution is obtained; Heating the pyrazole-carboxamide antifungal and anhydrous liquid carrier at 70°C. Contains.

In some embodiments, step (ii) is accomplished by mixing.

In some embodiments, step (ii) is performed without heating the mixture.

In some embodiments, the process involves mixing step (ii) before performing step (iii). It involves cooling to a temperature of <35°C.

In some embodiments, step (iii) is performed under agitation. Some In embodiments, step (iii) is performed under agitation of 1000 to 1500 rpm.

In some embodiments, the process may also include adjusting the viscosity of the composition by adding silica. It includes the step .

In some embodiments, the process may also include the antifungal oil in step (iii) before packaging. It involves filtering the liquid composition.

In some embodiments, the antifungal oil liquid composition in step (iii) is a homogeneous is the solution.

Each embodiment disclosed herein is compatible with each of the other embodiments disclosed. It is thought to be feasible. Therefore, the various elements described here All combinations are within the scope of the invention. In addition, in composition assemblies the elements specified, the combination, mixture (including synergistic mixture) disclosed herein, It can be used in package, method and usage arrangements and vice versa.

The present invention is described in more detail by reference to the following non-limiting examples. are shown and explained separately. The following examples are some shows the application of the current subject in its regulations, but It should not be interpreted as limiting its scope. Other embodiments, expert in the art It will be obvious when one considers the description and examples. Examples included The specification only includes, without limiting the scope and essence of the subject at hand. It is intended to set an example.

Experimental Examples The composition of Table 1 was made according to the following procedure: Hexanol, fluxapyroxad and tebuconazole were added and the active ingredients were dissolved completely. heated to 70°C. Then, it was turned off and mixed with Atlas SymperonicT'VI PE/F 68FL, TweenT'V' 24, antifoam, Rhodacal® 60/BE, tristyrylphenol 16 EC, methyl soyate and zinc oxide was added. The contents of the tank were cooled to <35°C.

Using the mixer type Cowles, mixing was increased to between 1000 and 1500 rpm and Mancozeb was added. Viscosity was adjusted using silica. Contents of the tank, room temperature and filtered (100 mesh sieves) before packaging.

Component CAS-No.: Chemical Common Function Source WN wi'w % as) [(dithiocarboxy)amino]ethyl]kar Sabero bamoditioalo(2-)- KS,KS']zinc with N-[2- bamoditioalo(2-)- KS,KS']manganese mixture iimetiI)pentane-3-0I il)pyrazole-4-carboxamide 2 solvents (low moisture) Ethoxylated (*

Claims (2)

CLAIMS It is an anti-fungal oil-liquid composition and its feature is; It contains (i) at least one dithiocarbamate antifungal, (ii) at least one triazole antifungal, (iii) at least one pyrazole-carboxamide antifungal, and (iv) at least one agrochemically acceptable non-aqueous liquid carrier. suspending the inhibitor in the liquid carrier and dissolving the triazole antifungal and pyrazole-carboxamide antifungal in the liquid carrier. It is a method according to claim 1 and its feature is; dithiocarbamate antifungal mancozeb. It is selected from the group consisting of maneb, metiram, propineb, thiram, zinc thiazole, zineb and ziram. It is a method according to claim 1 or 2 and its feature is; dithiocarbamate antifungal is mancozeb. It is a composition according to one of the claims 1-3; triazole antifungal; bittanol, bromuconazole, ciproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, flukinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole. is selected from the group consisting of simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole and protioconazole. It is a composition according to one of the claims 1-4, and its feature is; The triazole antifungal is prothioconazole. It is a composition according to one of the claims 1-5, and its feature is; The triazole antifungal is tebuconazole. It is a composition according to one of the claims 1-6 and its feature is; pyrozoic-carboxamide antifungals; It is the selection agent from the group consisting of benzovindifiupyr, bixafen, fluxapyroxad, furometpyr, isopyrosome, penflufen, pentiopyrod and sedoxane. It is a composition according to one of the claims 1-7, and its feature is; The pyrazole-carboxamide antifungal is fluxapyroxad. It is a composition according to one of the claims 1-8, and its feature is; amount of dithiocarbamate antifungal. approximately 0.1-80% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-9, and its feature is; The amount of dithiocarbamate antifungal is approximately 30-40% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-10, and its feature is; The amount of dithiocarbamate antifungal is approximately 35% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-11, and its feature is; The amount of dithiocarbamate antifungal in the composition is approximately 400-500 g/L. It is a composition according to one of the claims 1-12, and its feature is; The amount of dithiocarbamate antifungal in the composition is approximately 418 - 462 g/L. It is a composition according to one of the claims 1-13, and its feature is; The amount of dithiocarbamate antifungal in the composition is approximately 440 gL. It is a composition according to one of the claims 1-14, and its feature is; The amount of triazole antifungal is approximately 0.1-15% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-15, and its feature is; amount of triazole antifungal. approximately 2-5% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-16, and its feature is; It is a composition according to one of Claims 1-17, characterized in that the amount of triazole fungicide is 357% by weight, based on the total weight of the composition, or 357% by weight; The amount of triazole antifungal in the composition is approximately 20-60 g/L. It is a composition according to one of the claims 1-18, and its feature is; The triazole fungus in the composition is a composition according to one of the claims 1-19, and its feature is; The amount of triazole antifungal in the composition is approximately 44.5 g/L or approximately 31.5 g/L. It is a composition according to one of the claims 1-20, and its feature is; Composition according to one of claims 1-21, characterized in that the amount of pyrazole-carboxamide antifungal is estimated by weight based on the total weight of the composition; Composition according to one of claims 1-22, characterized in that the amount of pyrazole-carboxamide antifungal is estimated by weight based on the total weight of the composition; The amount of pyrazole-carboxamide antifungal is 1.77 wt% or 1.81 wt% based on the total weight of the composition. It is a composition according to one of the claims 1-23, and its feature is; The amount of pyrazole-carboxamide antifungal in the composition is approximately 15-30 g/L. It is a composition according to one of the claims 1-24, and its feature is; The amount of pyrazole-carboxamide antifungal in the composition is approximately 19.13 - 25.88 g/L. It is a composition according to one of the claims 1-25, and its feature is; The amount of pyrazole-carboxamide antifungal in the composition is approximately 22.5 g/L. It is a composition according to one of the claims 1-26, and its feature is; non-aqueous liquid carrier, aromatic hydrocarbons, paraffins, petroleum, alcohols, ketones, vegetable oil, alkyl ester of vegetable oils, diesel, mineral oil, alkyl amides, fatty acid amides, fatty acids, long fatty acids, alkyl esters of fatty acids, modified It is selected from the group consisting of vegetable oils and any combination thereof. It is a composition according to one of the claims 1-27, and its feature is; wherein the nonaqueous liquid carrier is selected from the group consisting of aromatic hydrocarbons, alkyl amides, alkyl ester of vegetable oils, alcohols, and any combination thereof. It is a composition according to one of the claims 1-28, and its feature is; The total amount of anhydrous liquid carrier in the composition is approximately 0.1-80% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-29, and its feature is; The total amount of anhydrous liquid carrier in the composition is approximately 35-40% by weight, based on the total weight of the composition. It is a composition according to one of the claims 1-30, and its feature is; The non-aqueous liquid carrier contains an aromatic hydrocarbon. It is a composition according to claim 31 and its feature is; The aromatic hydrocarbon solvent is naphtha. It is a composition according to one of the claims 1-32 and its feature is; The non-aqueous liquid carrier is the composition according to Claim 33 and its feature is; The alkyl amide is N,N-dimethyl decanamide, N,N-dimethyl octanamide, or a mixture thereof. It is a composition according to one of the claims 1-34, and its feature is; The non-aqueous liquid carrier contains an alkyl ester of vegetable oil. It is a composition according to claim 35 and its feature is; The alkyl ester of vegetable oil is the methyl ester of soybean oil. It is a composition according to one of the claims 1-36 and its feature is; The non-aqueous liquid carrier contains an alcohol. It is a composition according to claim 37 and its feature is; The alcohol is 2-ethyl hexanol. It is a composition according to one of the claims 1-36 and its feature is; wherein the nonaqueous liquid carrier is a combination of an aromatic hydrocarbon, an alkyl amide, and a vegetable oil alkyl ester. It is a composition according to one of the claims 1-37, and its feature is; The non-aqueous liquid carrier is a combination of solvent naphtha aromatic heavy 200, N,N-dimethyl decanamide and methyl ester of soybean oil. It is a composition according to one of the claims 1-38, and its feature is; wherein the nonaqueous liquid carrier is a combination of an aromatic hydrocarbon, an alkyl amide, a vegetable oil alkyl ester, and an alcohol. It is a composition according to one of the claims 1-38, and its feature is; The nonaqueous liquid carrier is a combination of the solvent naphtha aromatic heavy 200, N,N-dimethyl decanamide, methyl ester of soybean oil and 2-ethyl hexanol. It is a composition according to one of the claims 1-42, and its feature is; The composition contains at least one excipient. It is a composition according to claim 43 and its feature is; The auxiliary is polyoxyethylene (16) sorbitan monolaurate (TweenT'V' 24). It is a composition according to one of the claims 1-44, and its feature is; The antifungal oil liquid composition contains at least one surfactant. It is a composition according to claim 45 and its feature is; wherein the surfactant is selected from the group consisting of tristyrylphenol ethoxylates, alkyl benzene sulfonates and their salts, ethylene oxide-propylene oxide block copolymers, and any combination thereof. Composition according to claims 45 or 46; The composition contains three surfactants. It is a combination according to claim 47 and its feature is; The surfactants are a tristyrylphenol ethoxylate, an alkyl benzene sulfonate or a salt thereof, and an ethylene oxide-propylene oxide block copolymer. It is a composition according to claims 47 or 48, and its feature is; The surfactants are tristyrylphenol ethoxylated 16 EO, docesylbenzene sulfonate calcium salt and an ethylene oxide-propylene oxide block copolymer. It is a composition according to one of the claims 1-49, and its feature is; The composition includes adhesives, neutralizers, thickeners, binders, sequestrates, biocides, stabilizers, suspension aid, protective buffers, antioxidants, antifoaming agents and/or antifreezing agents. It is a composition according to claim 50 and its feature is; the composition comprising an antifoam agent, a stabilizer, or a suspending aid; a. the antifoam agent is polydimethylsiloxane, b. the stabilizer being zinc oxide and/or c. The suspension aid is silica, fumed silica, silicic anhydride, silicon dioxide and/or amorphous silicon dioxide. It is a composition according to one of the claims 1-51, and its feature is; The pH of the composition is 5.5-8.5. It is a composition according to one of the claims 1-52, and its feature is; The composition at 20°C is approximately 1- 1.5 g/cm3. It is a composition according to one of the claims 1-53, and its feature is; The density of the composition at 20°C is 1.245 g/cm3 or 1.27 g/cm3. It is a composition according to one of the claims 1-54, and its feature is; is the dilution of the composition in water. It is a composition according to one of the claims 1-55, and its feature is; The composition is chemically stable. It is a composition according to one of the claims 1-56, and its feature is; after 2 weeks of storage at room temperature, after 2 weeks of storage at 54°C, after 8 weeks of storage at room temperature, after 8 weeks of storage at 40°C, after 1 week of storage at 0°C, or after 1 week of storage at 40°C It is a composition according to one of Claims 1-57, characterized in that, after weekly storage, the dithiocarbamate antifungal is less than 35% degraded, the triazole antifungal is less than 20% degraded, and/or the pyrazole-carboxamide antifungal is a composition according to one of Claims 1-57. The composition is physically stable. It is a composition according to one of the claims 1-58, and its feature is; after 2 weeks of storage at room temperature, after 2 weeks of storage at 54°C, after 8 weeks of storage at room temperature, after 8 weeks of storage at 40°C, after 1 week of storage at 0°C, or after 1 week of storage at 40°C After weekly storage, it is a composition according to one of Claims 1-59, and its feature is; less than 2 mL of residue per 250 mL of the composition after 2 weeks of storage at room temperature, after 2 weeks of storage at 54°C, after 8 weeks of storage at room temperature, or after 8 weeks of storage at 40°C. It is a composition according to one of the claims 1-60, and its feature is; The composition is more effective for treating the plant or Iocus against fungal infection than the same amount of each antifungal applied separately or in a tank mix form, other than the compositions of any one of claims 1-60. It is a combination and its feature is; It provides a combination comprising (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal. It is a combination and its feature is; (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal, thereby preventing fungal infection of the plant or the combination, a plant or an Iocus. Each antifungal is more effective than applying the same amount alone. It is a combination and its feature is; (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal, so that the amount of herbal or dithiocarbamate antifungal is equal to the amount of triazole antifungal. and the pyrazole-carboxamide antifungal amount applied together is more effective than the application of one herb or amount alone. It is a combination and its feature is; (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal, such that the amount of the dithiocarbamate fungicide in the plant or The amount of dithiocarbamate antifungal that is effective as an antifungal when used alone is less than the amount of dithiocarbamate antifungal, when the triazole antifungal is used alone, the amount of triazole inhibitor is less than the amount of triazole antifungal that is effective as an antifungal, and/or the amount of pyrazole-carboxamide antifungal is less than the amount of pyrazole antifungal. When the -carboxamide antifungal is used alone, the amount of pyrazole-carboxamide antifungal is less than the antifungal effect. It is a composition according to one of the claims 62-65 and its feature is; The combination is synergistic. A mixture comprising the combination of any one of claims 62-66. An antifungal composition comprising the combination of any one of claims 62-66 or the mixture of claim 66. It is a method of treating a plant or a locus against fungal infection, and its feature is; applying the compound of any one of claims 1 to 61 and 68, the combination of any one of claims 62 to 66, or the mixture of claim 67 in an amount effective to treat the plant or locus against fungal infection. It is a method according to claim 69 and its feature is; The method comprising applying an effective amount of the composition of any one of claims 1 to 61 and 68 to the plant or locus. It is a method according to claim 69 and its feature is; is to dilute the composition in water before application. It is a method according to one of the claims 69-71 and its feature is; applying the composition at a rate of approximately 2.25 L/ha, approximately 2.5 L/ha, or approximately 2.75 L/ha. It is a method according to one of the claims 69-72, and its feature is; The application of the composition is intended to treat the plant or locus against fungal infection, in the same amount of each fungicide, in the form of a tank mix or separately. 1-60 is more effective than any of its combinations when applied in a different form. It is a method for treating a plant or a plant against fungal infection, and its feature is; to treat the plant or locus against fungal infection by applying (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal, dithiocarbamate antifungal. When the amount of triazole antifungal and the pyrazole-carboxamide antifungal amount are applied together, it is more effective in the treatment of a plant or a locus against fungal infection than when the same amount of each antifungal is applied alone. To treat a plant or locus against fungal infection, applying (i) an amount of at least one dithiocarbamate antifungal, (ii) an amount of at least one triazole antifungal, and (iii) an amount of at least one pyrazole-carboxamide antifungal, Thus, it is a method for treating plants or Iocus against fungal infection, and its feature is; the amount of dithiocarbamate antifungal applied is less than the antifungal effective amount of the dithiocarbamate antifungal when the dithiocarbamate antifungal is used alone, the amount of triazole antifungal applied is less than the antifungal effective amount of the triazole antifungal when the triazole antifungal is used alone, and/or The amount of pyrazole-carboxamide antifungal applied is less than the antifungal effective amount of pyrazole-carboxamide antifungal when the pyrazole-carboxamide antifungal is used alone. It is a method according to one of the claims 69-75, and its feature is; pyrazole-carboxamide antifungal is applied at a rate of between approximately 10 g a.i.lha and approximately 100 g a.i.lha. It is a method according to one of the claims 69-76, and its feature is; pyrazole-carboxamide antifungal is applied at a rate of approximately 50 g a.i.lha to approximately 65 g a.i.lha. It is a method according to one of the claims 69-77, and its feature is; triazole antifungal is applied at a rate of approximately 10 g a.i.lha to approximately 200 g a.i.lha. It is a method according to one of the claims 69-78, and its feature is; Triazole antifungal is applied at a ratio between It is a method according to one of the claims 69-79, and its feature is; dithiocarbamate antifungal is applied at a rate of approximately 100 g a.i.lha to approximately 2000 g a.i.lha. It is a method according to one of the claims 69-80, and its feature is; dithiocarbamate antifungal is applied at a rate of approximately 900 g a.i.lha to approximately 1200 g a.i.lha. The composition of any one of claims 1 to 61 and 68 for treating a plant or a locus against fungal infection, according to claim 6 Using the combination of any one of claims 2-66 or the mixture of claim 67. The composition of any one of claims 1 to 61 and 68, the combination of any of claims 62 to 66, or the mixture of claim 67 for use in treating a plant or a plant against fungal infection. A package comprising the combination of any one of claims 1-61 and 68, the combination of any one of claims 62-66, or the mixture of claim 67. A process for preparing the composition of any of claims 1-61 and 68, the combination of any of claims 62-66, or the mixture of claim 67 from separate component parts. It is a process for preparing the composition of any of the claims 1-61 and 68, and its feature is; dissolving at least one triazole antifungal and at least one pyrazole-carboxamide antifungal in at least one non-3qu liquid carrier to obtain a solution; adding at least one excipient, surfactant, antifoam agent and/or stabilizer to the solution in step (i) to obtain the mixture; and adding at least one dithiocarbamate antifungal to the mixture in step (ii) to obtain the antifungal oil composition. It is a process according to claim 86 and its feature is; . Performing step (i) under agitation, . step (i) comprising heating the triazole antifungal, the pyrazole-carboxamide antifungal, and the anhydrous liquid carrier until a solution is obtained. Perform step (ii) by mixing, . Perform step (ii) without heating the mixture, . the process comprising cooling the mixture in step (ii) to a temperature of <35°C before performing step (iii), e. performing step (iii) under agitation, f. the process further includes the step of adjusting the viscosity of the composition by adding silica, and/or g. The process further includes filtering the antifungal oil liquid composition of step (iii) before packaging. 87. It is a process according to claim 86 or 87, and its feature is; The antifungal oil liquid composition obtained in step (iii) is a homogeneous solution.