TR202011358A2 - Herbal composition that provides protection against viruses and has medicinal and pharmacological properties - Google Patents

Abstract

In particular, the invention relates to the herbal composition containing Artemisia annua extract and the powder of Artemisia annua herb and the production method of the mentioned herbal composition, which provides an antiviral effect and normalizes the modulation of the immune system, thus making it possible to treat the disease and prevent its contagiousness.

Description

DESCRIPTION Herbal with medicinal and pharmacological properties that provide protection against viruses composition Technical Field The invention covers viral diseases and epidemics that threaten human health and causes respiratory diseases. influenza, SARS, MERS-COV, SARS-CoV-2 etc. providing protection against viruses, medical and is related to the herbal composition with pharmacological properties.

In particular, the invention provides an antiviral effect and normalizes the immune system modulation. which enables the disease to be treated and thus prevents its contagion. Herbal formula containing Artemisia annua extract and Artemisia annua herbal powder, which makes it possible It is related to the composition and the production method of the said herbal composition.

Known Status of the Technique Viral infections are the general term for diseases caused by various types of viruses. is the name. Viruses cause infectious diseases known as colds, flu, and warts. It can also cause serious diseases such as HIV/AIDS, smallpox and hemorrhagic fever.

Viruses invade the cells in the living body and destroy these cells to reproduce and develop. is using. In other words, viruses need hosts to survive and reproduce. It requires cells. Viruses enter the cell, also called the host cell. It enters the cell and releases its DNA or RNA into the cell. The DNA or RNA of the virus It is the genetic material that contains the information necessary for reproduction. This genetic material is like a pirate It takes control of the cell and forces the cell to proliferate. infected with virus The infected cell usually dies because the virus takes over the cell's normal functions. is going through. When the cell dies, it releases a new virus that will infect other cells. is leaving. Some viruses, instead of killing the cells they infect, disrupt the cell's functions. It is changing. Sometimes the infected cell loses control over normal cell division function. and becomes a cancerous cell. Some viruses also spread inside the host cell. leaves its genetic material and this material remains inert inside the cell for a long time. remains (latent infection). When resistance drops, the virus copies itself again and disease may occur.

Viruses can usually infect a certain type of cell. For example, cold viruses It only infects cells in the upper respiratory tract. plants or animals only While it infects several species, some infect only humans. In some diseases It is difficult to distinguish whether the causative agent is bacteria or virus by looking at the symptoms. Pneumonia, meningitis, Many diseases, such as diarrhea, can be caused by both bacteria and viruses. bacteria and Perhaps the most important distinction between viruses is that antibiotic drugs kill bacteria but It does not affect viruses. Viruses live inside body cells and travel through the bloodstream. They are difficult to treat because they move. Currently, there are only a few antiviral drugs that are effective against viruses. is currently known. There are also vaccines to prevent many viral diseases.

One of the types of viruses that have caused social problems recently are coronaviruses.

Corona viruses are viruses that most people encounter at some point in their lives, and they It generally causes mild to moderate upper respiratory tract diseases. corona There are four subgroups of viruses known as alpha, beta, gamma and delta. corona viruses (CoV), from the common cold to Middle East Respiratory Syndrome (MERS-COV) and Severe Acute More serious diseases such as Severe Acute Respiratory Syndrome (SARS-CoV) It can cause a variety of diseases, including diseases.

Subtypes of coronaviruses circulating in humans (HCoV-229E, HCoV-OC43, HCoV- NL63 and HKU1-CoV) are viruses that mostly cause the common cold. SARS-CoV, 21. The first international health emergency of the century occurred in 2003, a previously unknown It emerged as a virus and caused hundreds of people to lose their lives.

After about 10 years, the coronavirus family, which had previously existed in humans or animals, not shown MERS-COV (Middle East Respiratory Syndrome Coronavirus) September It was first identified in humans in Saudi Arabia in 2012; but then actually the first It was revealed that the cases were seen in a hospital in Zarqa, Jordan, in April 2012. SARS Although it is distantly related to the coronavirus, it is based on the SARS experience. It has caused concern because of this. On 31 December 2019, WHO China Country Office reported that China's Hubei province He reported cases of pneumonia of unknown etiology in the city of Wuhan. Active on January 7, 2020 as a new coronavirus (2019-nCoV) that has not been detected in humans before has been defined. Later It was accepted as.

Viruses belonging to this group of viruses usually cause mild to moderate symptoms, similar to the common cold. It can make people with severe upper respiratory tract disease sick. COVID-19 Common symptoms of infection are respiratory symptoms, fever, cough and shortness of breath.

In more severe cases, pneumonia, severe acute respiratory infection, kidney failure and Even death may occur. However, based on the available data, the severity of the disease No clear comment can be made on this subject. Nowadays, there is no special treatment for COVID-19. There is no method. Most of the time, the symptoms disappear on their own. Specialist physicians diagnosis post-treatment with painkillers and antipyretics to relieve symptoms can apply it. Balancing the room humidity in living spaces and warming the throat with a warm shower It can help relieve pain and/or cough. Also, consuming plenty of fluids, It is beneficial for rest and sleep treatment. Symptoms are from the standard cold process When it starts to get worse, different treatment methods can be used under the supervision of a specialist physician. is implemented. Vaccines, medicines and treatments for use in the treatment of COVID-19 are available in the known art. Research and studies on these methods continue.

In the known state of the art, it is used in the treatment of COVID-19 infection. Some applications regarding the developed compositions were found. One of them is TR 2020 It is used and taken orally to treat gum recession and ulcer disease. coronavirus containing beneficial black seed oil, olive oil seed and clove oil It is related to the herbal anti-viral drug used for the disease (COVID-19).

In the application numbered TR 2020 05519, viral and bacterial upper respiratory tract It has an inhibitory effect on infections, especially on the replication of coronaviruses. stone anise root cure, which has a preventive and protective structure thanks to its The application method is explained. The cure subject to the invention is based on pentenyl ring volatile fatty acids and Contains anise root.

Artemisia annua, also known colloquially as Prophet's Broom In addition to helping lower blood pressure, it also has strengthening and protective effects on stomach health. There are. Thanks to the artemisinin substance it contains, it prevents some medically important diseases. It is used in treatment. In the known art, the antiviral effect and immune response of Arfemi'sia annua Some studies have been conducted on its regulatory effect on the release of mediators. This In one of the studies, homogenized samples of various artemisia species were used in vitro. Among the methanolic extracts, Arfemisi'a annua has the most intense anti-viral and anti-herpetic effect. has been reported to have (1). Similarly, pure artemisinin is effective against bovine viral diarrhea virus. It has been proven to be effective against In the study, bovine viral diarrhea from the flaviviridae family bovine epithelial cells infected with the virus were treated with artemisinin, and as a result It has been demonstrated that artemisinin has an inhibitory effect against the agent (2). Artemisia in 2005 In another study showing the antiviral effect of annua, it was found against hepatitis B virus. They divided the substances with antiviral activity into four groups and determined that artemisinin acts on host cells. by reducing Hepatitis B virus surface antigen in a dose-dependent manner in doses that do not cause harm They reported that it is the substance with the strongest viral inhibition activity (3). currently available Usability of Artemisia annua, especially in the treatment of contagious viral infections Research on the subject continues. However, influenza, SARS, MERS-CoV, SARS- Contagious viral infections caused by CoV-2 viruses and affecting the immune system No studies have been conducted on its usability in diseases.

As a result, due to the negativities and deficiencies mentioned above, the relevant technical A need for innovation in the field has emerged.

Purpose of the Invention The present invention meets the above-mentioned requirements and eliminates all the disadvantages. removing and bringing some additional advantages, providing protection against viruses, medical and It is related to the herbal composition that has pharmacological properties.

The purpose of the invention is to prevent infectious diseases caused by influenza, SARS, MERS-CoV, SARS-CoV-2 viruses. For use in viral infections and diseases affecting the immune system, it is completely To present a herbal composition.

The aim of the invention is to prevent disease, which does not adversely affect human health, thanks to its herbal content. improving the poor course of the disease, the side effects of the medications given and the contagious potential of the disease To put forward a composition that reduces

The purpose of the invention is to prevent COVID-19 caused by SARS-CoV-2 viruses of Artemisia annua. To demonstrate its usability in the medical treatment of infection.

The purpose of the invention is to determine the positive effects of phytochemicals in Artemisia annua on viral diseases. Thanks to its synergistic effect, it accelerates healing with existing treatments.

The purpose of the invention is to use Artemfsia annua as an effective and less toxic medicine and to increase its awareness.

The purpose of the invention is to save our national resources in the health industry during and after the pandemic. In order to fulfill the above-mentioned purposes, the invention is aimed at preventing viral infections that threaten human health. diseases and epidemics, influenza, SARS, MERS-CoV, which cause respiratory diseases, SARS-CoV-2 etc. herbal medicine that provides protection against viruses and has medicinal and pharmacological properties It is composition and its feature is; Although it provides an antiviral effect, it also modulates the immune system. which brings it back to normal and thus treats the disease and prevents its contagion. Artemisi'a annua extract and powder of Artemisi'a annua herb, which make it possible to prevent Contains.

In order to achieve the objectives of the invention, medical and Herbal composition with pharmacological properties, To obtain Artemisi'a annua extract, An'emi'si'a annua is applied to the aboveground part. Waiting for at least 24, maximum 96 hours and then filtering, filtering and evaporating. implementation of procedures, o To obtain the powder of An'emi'si'a annua herb, use the Artemisia annua plant. pulverizing the leafy and flowering parts, . obtained from Artemisi'a annua extract and powder of Artemisi'a annua herb It is produced by mixing process steps.

The detailed explanation of the structural and characteristic features and all the advantages of the invention is given below. Thanks to this, it will be understood more clearly and therefore the evaluation will be made in this detailed manner. The explanation should be taken into consideration.

Detailed Description of the Invention In this detailed explanation, products that provide protection against viruses and have medical and pharmacological properties are discussed. The herbal composition is intended only for a better understanding of the subject and has no It is explained in a way that does not create a limiting effect.

The invention covers viral diseases and epidemics that threaten human health and causes respiratory diseases. influenza, SARS, MERS-COV, SARS-CoV-2 etc. providing protection against viruses, medical and is related to the herbal composition with pharmacological properties. Feature of the invention, antiviral effect It also provides normalization of immune system modulation and Artemisfa, which makes it possible to treat the disease and prevent its contagion It contains annua extract and Artemisia annua herb powder.

The herbal composition formulation subject to the invention; Content Available by weight preferred by weight quantity (%) quantity (%) Artemisia annua extract 60 50-90 Artemisia annua herb powder 40 10-50 Artemisia annua extract provides antiviral effect and optimizes immune system modulation. Contains compounds that As Artemisia annua extract, this rich content is more intense. can be obtained in some way.

The extract of Artemisia annua herb is less likely to change during processing. Phytochemicals and volatile substances that may be present in the proportions found in the original plant composition and can be preserved within the natural structure of the herb. And preserved in herbanin powder These compounds contribute to the invention.

Positive synergistic effect of phytochemicals in Artemisia annual on viral diseases It accelerates recovery with existing treatments. Artemisia annua, currently anti-inflammatory, with proven broad antimicrobial and anti-viral effects regulatory effect on the release of immune mediators and its immune response in many organisms. A synergistic effect occurs by activating and regulating many pathways in the system. This It contains Camphene, Artemisia ketone, Linalool, Artemisia alcohol, 1.8 Cineole. sesquiterpenes with volatile terpene and terpenoid compounds and other phytochemical properties such as The production method of the herbal composition subject to the invention is as follows; Artemisia annua extract is extracted from the aerial part of Artemisia annua in ethyl alcohol. It is prepared by . 80%-96% ethyl alcohol by volume 1:2 to 1:5 to plant material ratio is added and left to wait for at least 24 and at most 96 hours. Holding process takes approximately 20-25 minutes It is carried out at a temperature of °C. Intermittent shaking during the holding process is being done. At the end of the holding process, filtering, filtering and evaporating processes are performed respectively. Artemisia annua extract is obtained by applying The powder of Artemisia annua herb is: It is obtained by pulverizing the leafy and flowering parts of the Artemisia annua plant. is done. In the final stage, Artemisia annua extract and Artemisia annua herb powder is mixed.

The plant composition obtained by the method of the invention is in solid form and is effective against influenza, SARS, Contagious viral infections and immune disorders caused by MERS-COV, SARS-CoV-2 viruses taken orally one to three times a day in the treatment of diseases affecting the is used.

Claims (5)

1. Viral diseases and epidemics that threaten human health, influenza that causes respiratory diseases, SARS, MERS-COV, SARS-CoV-2 (COVlD-19), etc. It is a herbal composition that provides protection against viruses and has medicinal and pharmacological properties. It contains Arfemfsia annua extract and Artemisia annua herb powder, which provides an antiviral effect and allows to normalize the immune system modulation, thus making it possible to treat the disease and prevent its contagion. 2. It is a herbal composition according to claim 1, and its feature is; It contains 50-90% by weight of Artemisi'a annua extract and 10-50% by weight of Arfemi'si'a annua herbal powder. 3. It is the production method of the herbal composition mentioned in any of the above claims and its feature is; o To obtain Artemisi'a annua extract, keeping the aboveground part of Artemisia annua for at least 24, maximum 96 hours and then applying the filtering, filtering and evaporating processes, o To obtain the powder of Artemisi'a annua herb, It includes the process steps of pulverizing the leafy and flowering parts of the plant, mixing the resulting Arfemi'sia annua extract and the powder of the Artemisi'a annua herb. 4. The herbal composition obtained by the production method mentioned in claim 3 is in solid form. 5. The herbal composition obtained by the production method mentioned in claim 3 is to be used orally one to three times a day in the treatment of contagious viral infections caused by influenza, SARS, MERS-COV, SARS-CoV-2 viruses and diseases affecting the immune system.