TR202002069A2 - Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇ - Google Patents

Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇

Info

Publication number
TR202002069A2
TR202002069A2 TR2020/02069A TR202002069A TR202002069A2 TR 202002069 A2 TR202002069 A2 TR 202002069A2 TR 2020/02069 A TR2020/02069 A TR 2020/02069A TR 202002069 A TR202002069 A TR 202002069A TR 202002069 A2 TR202002069 A2 TR 202002069A2
Authority
TR
Turkey
Prior art keywords
inhibitor
bcl
physics
therapeutic compounds
novel small
Prior art date
Application number
TR2020/02069A
Other languages
English (en)
Inventor
Doğan Berna
Çaçan Gurbet
Di̇dem Orhan Müge
Durdaği Serdar
Avşar Ti̇muçi̇n
Çaliş Şeyma
Original Assignee
Bahcesehir Ueniversitesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bahcesehir Ueniversitesi filed Critical Bahcesehir Ueniversitesi
Priority to TR2020/02069A priority Critical patent/TR202002069A2/tr
Priority to PCT/TR2021/050120 priority patent/WO2021162666A1/en
Priority to US17/929,007 priority patent/US20230109522A1/en
Publication of TR202002069A2 publication Critical patent/TR202002069A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Buluş yeni bir BCL-2 inhibitörü olarak kullanılmak üzere formül I ile gösterilen bileşik veya bunun farmasötik olarak kabul edilebilir bir türevi ile ilgilidir
TR2020/02069A 2020-02-11 2020-02-11 Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇ TR202002069A2 (tr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
TR2020/02069A TR202002069A2 (tr) 2020-02-11 2020-02-11 Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇
PCT/TR2021/050120 WO2021162666A1 (en) 2020-02-11 2021-02-10 Physics-driven discovery of novel small therapeutic compounds for use as a bcl-2 inhibitor
US17/929,007 US20230109522A1 (en) 2020-02-11 2021-02-10 Physics-driven discovery of novel small therapeutic compounds for use as a bcl-2 inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2020/02069A TR202002069A2 (tr) 2020-02-11 2020-02-11 Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇

Publications (1)

Publication Number Publication Date
TR202002069A2 true TR202002069A2 (tr) 2021-08-23

Family

ID=77292497

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2020/02069A TR202002069A2 (tr) 2020-02-11 2020-02-11 Bcl-2 i̇nhi̇bi̇törü olarak kullanilan yeni̇ küçük terapöti̇k bi̇leşi̇kleri̇n fi̇zi̇k odakli olarak keşfi̇

Country Status (3)

Country Link
US (1) US20230109522A1 (tr)
TR (1) TR202002069A2 (tr)
WO (1) WO2021162666A1 (tr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009086303A2 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms

Also Published As

Publication number Publication date
US20230109522A1 (en) 2023-04-06
WO2021162666A1 (en) 2021-08-19

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