TR201820875A2 - Geli̇şti̇ri̇lmi̇ş oksi̇metazoli̇n hi̇droklorür i̇çeren nazal damla formülasyonlari - Google Patents
Geli̇şti̇ri̇lmi̇ş oksi̇metazoli̇n hi̇droklorür i̇çeren nazal damla formülasyonlari Download PDFInfo
- Publication number
- TR201820875A2 TR201820875A2 TR2018/20875A TR201820875A TR201820875A2 TR 201820875 A2 TR201820875 A2 TR 201820875A2 TR 2018/20875 A TR2018/20875 A TR 2018/20875A TR 201820875 A TR201820875 A TR 201820875A TR 201820875 A2 TR201820875 A2 TR 201820875A2
- Authority
- TR
- Turkey
- Prior art keywords
- hydrochloride
- weight
- oxymethetazoline
- nazal
- formulations containing
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- WYWIFABBXFUGLM-UHFFFAOYSA-N oxymetazoline Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C)=C1CC1=NCCN1 WYWIFABBXFUGLM-UHFFFAOYSA-N 0.000 abstract 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000007923 nasal drop Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 229960001528 oxymetazoline Drugs 0.000 abstract 1
- 229960005162 oxymetazoline hydrochloride Drugs 0.000 abstract 1
- BEEDODBODQVSIM-UHFFFAOYSA-N oxymetazoline hydrochloride Chemical compound Cl.CC1=CC(C(C)(C)C)=C(O)C(C)=C1CC1=NCCN1 BEEDODBODQVSIM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Abstract
Mevcut buluş, farmasötik teknoloji alanı ile ilgilidir ve oksimetazolin hidroklorür içeren nazal damla formülasyonu olup, özelliği; etkin madde olarak ağırlıkça % 0.01 oranında oksimetazolin 5 hidroklorür, nötralize edici yardımcı madde olarak ağırlıkça % 0.02 -% 0.2 oranında disodyum edetat, tonisite ayarlayıcı madde olarak ağırlıkça % 0.5 - % 1.2 oranında sodyum klorür, antimikrobiyal koruyucu madde olarak ağırlıkça % 0.01 - % 0.02 oranında benzalkonyum klorür içermesi ile karakterize edilmesidir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2018/20875A TR201820875A2 (tr) | 2018-12-28 | 2018-12-28 | Geli̇şti̇ri̇lmi̇ş oksi̇metazoli̇n hi̇droklorür i̇çeren nazal damla formülasyonlari |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2018/20875A TR201820875A2 (tr) | 2018-12-28 | 2018-12-28 | Geli̇şti̇ri̇lmi̇ş oksi̇metazoli̇n hi̇droklorür i̇çeren nazal damla formülasyonlari |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201820875A2 true TR201820875A2 (tr) | 2019-04-22 |
Family
ID=67981238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2018/20875A TR201820875A2 (tr) | 2018-12-28 | 2018-12-28 | Geli̇şti̇ri̇lmi̇ş oksi̇metazoli̇n hi̇droklorür i̇çeren nazal damla formülasyonlari |
Country Status (1)
| Country | Link |
|---|---|
| TR (1) | TR201820875A2 (tr) |
-
2018
- 2018-12-28 TR TR2018/20875A patent/TR201820875A2/tr unknown
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