TR201820768A2 - Vi̇ldagli̇pti̇n i̇çeren geli̇şti̇ri̇lmi̇ş çözünme hizina sahi̇p tablet formülasyonlari - Google Patents
Vi̇ldagli̇pti̇n i̇çeren geli̇şti̇ri̇lmi̇ş çözünme hizina sahi̇p tablet formülasyonlari Download PDFInfo
- Publication number
- TR201820768A2 TR201820768A2 TR2018/20768A TR201820768A TR201820768A2 TR 201820768 A2 TR201820768 A2 TR 201820768A2 TR 2018/20768 A TR2018/20768 A TR 2018/20768A TR 201820768 A TR201820768 A TR 201820768A TR 201820768 A2 TR201820768 A2 TR 201820768A2
- Authority
- TR
- Turkey
- Prior art keywords
- vildagliptin
- weight
- dissolution rate
- tablet formulations
- improved dissolution
- Prior art date
Links
- SYOKIDBDQMKNDQ-XWTIBIIYSA-N vildagliptin Chemical compound C1C(O)(C2)CC(C3)CC1CC32NCC(=O)N1CCC[C@H]1C#N SYOKIDBDQMKNDQ-XWTIBIIYSA-N 0.000 title abstract 3
- 229960001254 vildagliptin Drugs 0.000 title abstract 3
- 239000007916 tablet composition Substances 0.000 title abstract 2
- 238000004090 dissolution Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- GUBGYTABKSRVRQ-DCSYEGIMSA-N Beta-Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-DCSYEGIMSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 238000007908 dry granulation Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229940079832 sodium starch glycolate Drugs 0.000 abstract 1
- 229920003109 sodium starch glycolate Polymers 0.000 abstract 1
- 239000008109 sodium starch glycolate Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Mevcut buluş farmasötik teknoloji alanı ile ilgilidir ve vildagliptin veya farmasötik olarak kabul edilebilir bir tuzu veya polimorfu içeren tablet formülasyonu olup, özelliği; etkin madde olarak 5 ağırlıkça %23 - %27 aralığında, d(90)<70 mikron, d(20)<30 mikron partikül boyutuna sahip vildagliptin veya farmasötik olarak kabul edilebilir bir tuzu veya polimorfunu, dağıtıcı ajan olarak ağırlıkça %2 - %6 oranında sodyum nişasta glikolat, seyreltici ajan olarak ağırlıkça %9 - %11 oranında laktoz anhidrus içermesi ve üretim yöntemi olarak kuru granülasyon üretim yönteminin kullanılması ile karakterize edilmesidir
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2018/20768A TR201820768A2 (tr) | 2018-12-27 | 2018-12-27 | Vi̇ldagli̇pti̇n i̇çeren geli̇şti̇ri̇lmi̇ş çözünme hizina sahi̇p tablet formülasyonlari |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2018/20768A TR201820768A2 (tr) | 2018-12-27 | 2018-12-27 | Vi̇ldagli̇pti̇n i̇çeren geli̇şti̇ri̇lmi̇ş çözünme hizina sahi̇p tablet formülasyonlari |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201820768A2 true TR201820768A2 (tr) | 2019-02-21 |
Family
ID=67955475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2018/20768A TR201820768A2 (tr) | 2018-12-27 | 2018-12-27 | Vi̇ldagli̇pti̇n i̇çeren geli̇şti̇ri̇lmi̇ş çözünme hizina sahi̇p tablet formülasyonlari |
Country Status (1)
| Country | Link |
|---|---|
| TR (1) | TR201820768A2 (tr) |
-
2018
- 2018-12-27 TR TR2018/20768A patent/TR201820768A2/tr unknown
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