TR201605339A2 - Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem - Google Patents

Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem Download PDF

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Publication number
TR201605339A2
TR201605339A2 TR2016/05339A TR201605339A TR201605339A2 TR 201605339 A2 TR201605339 A2 TR 201605339A2 TR 2016/05339 A TR2016/05339 A TR 2016/05339A TR 201605339 A TR201605339 A TR 201605339A TR 201605339 A2 TR201605339 A2 TR 201605339A2
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Turkey
Prior art keywords
production
vein
stent
laser
alloy
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TR2016/05339A
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English (en)
Inventor
Bi̇ndal Cuma
Findik Fehi̇m
İyi̇bi̇lgi̇n Osman
Gökçe Azi̇m
Özacar Mahmut
Akdemi̇r Ramazan
Original Assignee
Azim Goekce
Cuma Bindal
Fehim Findik
Mahmut Oezacar
Osman Iyibilgin
Ramazan Akdemir
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Application filed by Azim Goekce, Cuma Bindal, Fehim Findik, Mahmut Oezacar, Osman Iyibilgin, Ramazan Akdemir filed Critical Azim Goekce
Priority to TR2016/05339A priority Critical patent/TR201605339A2/tr
Publication of TR201605339A2 publication Critical patent/TR201605339A2/tr
Priority to PCT/TR2017/050159 priority patent/WO2017188908A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
    • B22F10/20—Direct sintering or melting
    • B22F10/28—Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
    • B22F10/30—Process control
    • B22F10/32—Process control of the atmosphere, e.g. composition or pressure in a building chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
    • B22F10/30—Process control
    • B22F10/36—Process control of energy beam parameters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F12/00—Apparatus or devices specially adapted for additive manufacturing; Auxiliary means for additive manufacturing; Combinations of additive manufacturing apparatus or devices with other processing apparatus or devices
    • B22F12/40—Radiation means
    • B22F12/44—Radiation means characterised by the configuration of the radiation means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C33/00—Making ferrous alloys
    • C22C33/02—Making ferrous alloys by powder metallurgy
    • C22C33/0257—Making ferrous alloys by powder metallurgy characterised by the range of the alloying elements
    • C22C33/0278—Making ferrous alloys by powder metallurgy characterised by the range of the alloying elements with at least one alloying element having a minimum content above 5%
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C38/00—Ferrous alloys, e.g. steel alloys
    • C22C38/002—Ferrous alloys, e.g. steel alloys containing In, Mg, or other elements not provided for in one single group C22C38/001 - C22C38/60
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C38/00—Ferrous alloys, e.g. steel alloys
    • C22C38/02—Ferrous alloys, e.g. steel alloys containing silicon
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C38/00—Ferrous alloys, e.g. steel alloys
    • C22C38/04—Ferrous alloys, e.g. steel alloys containing manganese
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C38/00—Ferrous alloys, e.g. steel alloys
    • C22C38/10—Ferrous alloys, e.g. steel alloys containing cobalt
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C38/00—Ferrous alloys, e.g. steel alloys
    • C22C38/12—Ferrous alloys, e.g. steel alloys containing tungsten, tantalum, molybdenum, vanadium, or niobium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00—Technologies related to metal processing
    • Y02P10/25—Process efficiency

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Metallurgy (AREA)
  • Mechanical Engineering (AREA)
  • Automation & Control Theory (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Buluş, damar içine yerleştirilen ve hemen sonrasında belli ölçüde genişletilerek damar içinde akışın gerektiği şekilde devamını sağlayan geçirgen, boruya benzer metal alaşımlı stent olup; biyoçözünür stentlerin üretimi için Fe-Mn-X-Y alaşımı içermesi, X' in Si, Co, Mo' den oluşan gruptan seçilen en az bir eleman içermesi, Y' nin ise C ve Pd?den oluşan gruptan seçilen en az bir eleman içermesi, bahsedilen alaşımın ağırlıkça Fe %47-75, Mn %20-35, Si %1-6, Co %1-4, Mo %1-4, C %1-2, Pd %1-2 olması ile karakterize edilmektedir. Buluş, damar içine yerleştirilen ve hemen sonrasında belli ölçüde genişletilerek damar içinde akışın gerektiği şekilde devamını sağlayan geçirgen, boruya benzer metal alaşımlı stent üretimi için yöntem olup; - üretimin 3D yazıcı ile gerçekleştirilmesi, - üretim esnasında 200-400 W gücünde bir lazer kaynağı kullanılması, - alaşımı oluşturan tozların üretim havuzu içerisinde yer alan tabla üzerine düzgün bir şekilde serilmesi, - Lazer kaynağının tablanın üst orta noktasında ve tabladan odak mesafesi kadar uzaklıkta kalacak şekilde, sabit olarak konumlandırılması, - Lazer ışınlarının istenilen noktaya yönlendirilmesini sağlamak amacıyla aynalardan faydalanılması, - üretim sırasında, aynalar vasıtasıyla lazer ışınlarının yönlendirilerek her bir katmanın taranması ve istenilen geometri elde edilecek şekilde birleştirmenin gerçekleştirilmesi işlem adımlarını içermesi, üretim esnasında ortalama toz boyutunun 5-20 mikron, lazer gücünün 200-400 W, tarama hızının 10 m/s - 20 m/s, lazer huzmesinin çapının 80 µm - 150 µm, katman yüksekliğinin 20 µm - 200 µm aralığında olması ve üretim sırasında koruyucu atmosfer olarak argon ya da azot gazı kullanılması ile karakterize edilmektedir.
TR2016/05339A 2016-04-25 2016-04-25 Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem TR201605339A2 (tr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2016/05339A TR201605339A2 (tr) 2016-04-25 2016-04-25 Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem
PCT/TR2017/050159 WO2017188908A1 (en) 2016-04-25 2017-04-24 Intravenously implanted metal alloy stent and a new method for the production of this stent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2016/05339A TR201605339A2 (tr) 2016-04-25 2016-04-25 Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem

Publications (1)

Publication Number Publication Date
TR201605339A2 true TR201605339A2 (tr) 2017-02-21

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ID=59295285

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TR2016/05339A TR201605339A2 (tr) 2016-04-25 2016-04-25 Damar İçine Yerleştirilen Metal Alaşımlı Stent ve Bu Stentin Üretimi İçin Yeni Bir Yöntem

Country Status (2)

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TR (1) TR201605339A2 (tr)
WO (1) WO2017188908A1 (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202000003611A1 (it) 2020-02-21 2021-08-21 Getters Spa Leghe Fe-Mn-X-Y bioassorbibili pseudoelastiche per impianti medici
IT202000007717A1 (it) 2020-04-10 2021-10-10 Getters Spa Leghe Fe-Mn-Si-X bioassorbibili per impianti medici
AU2022235029A1 (en) * 2021-03-11 2023-09-07 Newsouth Innovations Pty Limited Shape memory alloy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010203541A1 (en) * 2009-01-08 2011-08-25 Bio Dg, Inc. Implantable medical devices comprising bio-degradable alloys
US20100217370A1 (en) * 2009-02-20 2010-08-26 Boston Scientific Scimed, Inc. Bioerodible Endoprosthesis
JP2014533152A (ja) * 2011-10-20 2014-12-11 メドトロニック ヴァスキュラー インコーポレイテッド 生体吸収性ステント用の鉄系合金
US10085859B2 (en) * 2013-07-03 2018-10-02 Medtronic Vascular, Inc. Methods of manufacturing a drug-eluting stent
US9114032B1 (en) * 2014-05-21 2015-08-25 Medtronic Vascular, Inc. Method of making a stent

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