TR200907179A1 - Flurbiprofen ve kas gevşetici jel kombinasyonları - Google Patents

Flurbiprofen ve kas gevşetici jel kombinasyonları

Info

Publication number
TR200907179A1
TR200907179A1 TR2009/07179A TR200907179A TR200907179A1 TR 200907179 A1 TR200907179 A1 TR 200907179A1 TR 2009/07179 A TR2009/07179 A TR 2009/07179A TR 200907179 A TR200907179 A TR 200907179A TR 200907179 A1 TR200907179 A1 TR 200907179A1
Authority
TR
Turkey
Prior art keywords
flurbiprofen
thiocolchicoside
muscle relaxant
combinations
menthol
Prior art date
Application number
TR2009/07179A
Other languages
English (en)
Inventor
Çakir Fati̇h
Türkyilmaz Ali̇
Çi̇fter Ümi̇t
Original Assignee
Sanovel İlaç San. Ve Ti̇c. A. Ş.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanovel İlaç San. Ve Ti̇c. A. Ş. filed Critical Sanovel İlaç San. Ve Ti̇c. A. Ş.
Priority to TR2009/07179A priority Critical patent/TR200907179A1/tr
Priority to PL10177380T priority patent/PL2298280T3/pl
Priority to ES10177380.2T priority patent/ES2443570T3/es
Priority to EP10177380.2A priority patent/EP2298280B1/en
Priority to PT101773802T priority patent/PT2298280E/pt
Priority to US12/885,602 priority patent/US8691778B2/en
Publication of TR200907179A1 publication Critical patent/TR200907179A1/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Topikal uygulamaya uygun bir farmasötik jel olup, flurbiprofen veya farmasötik olarak kabul edilebilir bir tuzunu, tiyokolşikosid veya tiyokolşikosidin farmasötik olarak kabul edilebilir bir türevini ve mentol içermesi ile karakterize edilmektedir. Daha özel olarak bu buluş, flurbiprofen, tiyokolşikosid ve mentolün antienflamatuar, analjezik ve miyoroölaksan aktiviteye sahip, topikal uygulanan, jel şeklindeki farmasötik kombinasyonları ile ilgilidir.
TR2009/07179A 2009-09-18 2009-09-18 Flurbiprofen ve kas gevşetici jel kombinasyonları TR200907179A1 (tr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
TR2009/07179A TR200907179A1 (tr) 2009-09-18 2009-09-18 Flurbiprofen ve kas gevşetici jel kombinasyonları
PL10177380T PL2298280T3 (pl) 2009-09-18 2010-09-17 Żel zawierający kombinację flurbiprofenu i środka rozluźniającego mięśnie
ES10177380.2T ES2443570T3 (es) 2009-09-18 2010-09-17 Gel que comprende una combinación de flurbiprofeno y relajante muscular
EP10177380.2A EP2298280B1 (en) 2009-09-18 2010-09-17 Gel comprising a combination of flurbiprofen and muscle relaxant
PT101773802T PT2298280E (pt) 2009-09-18 2010-09-17 Gel que compreende u m a combinação de flurbiprofeno e relaxante muscular
US12/885,602 US8691778B2 (en) 2009-09-18 2010-09-20 Flurbiprofen and muscle relaxant gel combinations thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2009/07179A TR200907179A1 (tr) 2009-09-18 2009-09-18 Flurbiprofen ve kas gevşetici jel kombinasyonları

Publications (1)

Publication Number Publication Date
TR200907179A1 true TR200907179A1 (tr) 2011-04-21

Family

ID=41353990

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2009/07179A TR200907179A1 (tr) 2009-09-18 2009-09-18 Flurbiprofen ve kas gevşetici jel kombinasyonları

Country Status (6)

Country Link
US (1) US8691778B2 (tr)
EP (1) EP2298280B1 (tr)
ES (1) ES2443570T3 (tr)
PL (1) PL2298280T3 (tr)
PT (1) PT2298280E (tr)
TR (1) TR200907179A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200708925A1 (tr) * 2007-12-26 2009-07-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Kontrollü salım sağlayan flurbiprofen ve kas gevşetici kombinasyonları
CN111904925A (zh) * 2020-04-28 2020-11-10 湖南九典制药股份有限公司 氟比洛芬钠凝胶制剂及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007129162A2 (en) * 2006-04-26 2007-11-15 Alma Mater Studiorum - Universita' Di Bologna Pharmaceutical preparations for transdermal use
EP1992333A1 (en) * 2007-05-08 2008-11-19 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Flurbiprofen and muscle relaxant combinations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2075837B (en) * 1980-05-14 1984-03-14 Hisamitsu Pharmaceutical Co Topical pharmaceutical gel containing anti-inflammatory analgesic agents
US4473584A (en) * 1982-12-06 1984-09-25 The Upjohn Company Treatment of Type I Herpes virus with flurbiprofen
GB9404248D0 (en) 1994-03-05 1994-04-20 Boots Co Plc Pharmaceutical formulations
FR2725134B1 (fr) 1994-10-04 1996-12-20 Lederle Lab Nouvelle association pharmaceutique a base d'ibuprofene et de thiocolchicoside
US5807568A (en) 1994-12-27 1998-09-15 Mcneil-Ppc, Inc. Enhanced delivery of topical compositions containing flurbiprofen
FR2735369B1 (fr) 1995-06-13 1997-07-11 Synthelabo Compositions pharmaceutiques a base de sel de sodium du diclofenac et de thiocolchicoside
WO1998052545A1 (en) 1997-05-22 1998-11-26 The Boots Company Plc Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007129162A2 (en) * 2006-04-26 2007-11-15 Alma Mater Studiorum - Universita' Di Bologna Pharmaceutical preparations for transdermal use
EP1992333A1 (en) * 2007-05-08 2008-11-19 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Flurbiprofen and muscle relaxant combinations

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LOGANATHAN V ET AL: "The effects of polymers and permeation enhancers on releases of flurbiprofen from gel formulations", INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, MEDKNOW PUBLICATIONS PVT LTD, IN, vol. 63, no. 3, 1 May 2001 (2001-05-01), pages 200 - 204, XP008115270, ISSN: 0250-474X *
MORIMOTO, Y. ET AL: "Effect of l-Menthol-Ethanol-Water System on the Systemic Absorption of Flurbiprofen after Repeated Topical Applications in Rabbits", BIOLOGICAL & PHARMACEUTICAL BULLETIN (OF JAPAN)., vol. 23, no. 10, 1 October 2000 (2000-10-01), PHARMACEUTICAL SOCIETY OF JAPAN, TOKYO., pages 1254 - 1257, XP002576678, ISSN: 0918-6158 *

Also Published As

Publication number Publication date
EP2298280A2 (en) 2011-03-23
EP2298280B1 (en) 2013-11-06
ES2443570T3 (es) 2014-02-19
US8691778B2 (en) 2014-04-08
US20110071098A1 (en) 2011-03-24
PT2298280E (pt) 2014-01-20
PL2298280T3 (pl) 2014-03-31
EP2298280A3 (en) 2011-06-01

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