TR200200571T2 - Alfa-2/delta geni - Google Patents

Alfa-2/delta geni

Info

Publication number
TR200200571T2
TR200200571T2 TR2002/00571T TR200200571T TR200200571T2 TR 200200571 T2 TR200200571 T2 TR 200200571T2 TR 2002/00571 T TR2002/00571 T TR 2002/00571T TR 200200571 T TR200200571 T TR 200200571T TR 200200571 T2 TR200200571 T2 TR 200200571T2
Authority
TR
Turkey
Prior art keywords
alpha
genes
gene
delta gene
polypeptides
Prior art date
Application number
TR2002/00571T
Other languages
English (en)
Inventor
Ann Johns Margaret
Moldover Brian
David Offord James
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of TR200200571T2 publication Critical patent/TR200200571T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

Bu bulus, üç yeni gene ve bu genlerden türetilen, bir çok kalsiyum kanalinda bir alt-birim halinde varolan, ''alfa2delta-C'' ve/veya ''alfa2delta-D'' proteinlerini kodlayan polipeptidlere iliskindir. Bulus, ayni zamanda, yeni gen ve polipeptidlerin, genin genetik silinmelerinin bulgulanmasinda, polipeptidin subselüler konumlanisinda, kimyasal veri tabanlari ile baglantili baglanma tahlillerinde, gen terapisinde kullanilmasi için yöntemleri de anlatmaktadir.
TR2002/00571T 1998-10-07 1999-10-07 Alfa-2/delta geni TR200200571T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10332298P 1998-10-07 1998-10-07
US10647398P 1998-10-30 1998-10-30
US11408898P 1998-12-29 1998-12-29

Publications (1)

Publication Number Publication Date
TR200200571T2 true TR200200571T2 (tr) 2002-06-21

Family

ID=27379516

Family Applications (4)

Application Number Title Priority Date Filing Date
TR2001/00937T TR200100937T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta geni
TR2002/00571T TR200200571T2 (tr) 1998-10-07 1999-10-07 Alfa-2/delta geni
TR2002/00632T TR200200632T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta Geni
TR2002/00631T TR200200631T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta geni

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2001/00937T TR200100937T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta geni

Family Applications After (2)

Application Number Title Priority Date Filing Date
TR2002/00632T TR200200632T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta Geni
TR2002/00631T TR200200631T2 (tr) 1998-10-07 1999-10-07 Alfa-2/Delta geni

Country Status (7)

Country Link
US (1) US7262052B1 (tr)
EP (1) EP1117796A2 (tr)
JP (1) JP2002526100A (tr)
AU (1) AU1106500A (tr)
CA (1) CA2341351A1 (tr)
TR (4) TR200100937T2 (tr)
WO (1) WO2000020450A2 (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6783952B1 (en) 1999-09-16 2004-08-31 Warner-Lambert Company Secreted soluble α2δ-2, α2δ-3 or α2δ-4 calcium channel subunit polypeptides and screening assays using same
BR0014090A (pt) * 1999-09-16 2002-05-21 Warner Lambert Co Método para rastreamento de ligandos de ligação à subunidade alfa2delta-1
US6962973B1 (en) 1999-09-16 2005-11-08 Warner-Lambert Company Porcine α2δ-1 calcium channel subunit cDNA and soluble secreted α2δ-1 subunit polypeptides
AU2001255448A1 (en) 2000-04-17 2001-10-30 Stephen B. Liggett Alpha-2 adrenergic receptor polymorphisms
US20020081657A1 (en) * 2000-06-05 2002-06-27 Curtis Rory A.J. 21784, a novel human calcium channel family member and uses thereof
US7294691B1 (en) 2000-09-18 2007-11-13 Warner Lambert Company Soluble secreted α2δ-2calcium channel subunit polypeptide
US7524643B2 (en) 2001-04-11 2009-04-28 Ortho-Mcneil Pharmaceutical, Inc. CDNA encoding the human alpha2 delta4 calcium channel subunit
US7049084B2 (en) 2001-05-30 2006-05-23 Ortho-Mcneil Pharmaceutical, Inc. Neuroblastoma cell lines expressing the α2δ subunit of calcium channels and methods therefore
WO2006031955A2 (en) 2004-09-14 2006-03-23 The Regents Of The University Of Colorado, A Body Corporate Method for treatment with bucindolol based on genetic targeting

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874236A (en) 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US6040436A (en) * 1996-09-16 2000-03-21 American Home Products Corporation Nucleic acid encoding human neuronal calcium channel subunits
WO2000012711A2 (en) 1998-09-02 2000-03-09 Incyte Pharmaceuticals, Inc. Human membrane channel proteins

Also Published As

Publication number Publication date
US7262052B1 (en) 2007-08-28
TR200100937T2 (tr) 2001-10-22
AU1106500A (en) 2000-04-26
WO2000020450A9 (en) 2001-04-05
TR200200632T2 (tr) 2002-07-22
EP1117796A2 (en) 2001-07-25
CA2341351A1 (en) 2000-04-13
TR200200631T2 (tr) 2002-06-21
JP2002526100A (ja) 2002-08-20
WO2000020450A3 (en) 2000-11-23
WO2000020450A2 (en) 2000-04-13

Similar Documents

Publication Publication Date Title
DK1005540T3 (da) IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
ATE418563T1 (de) Nik proteine, nukleinsäure sowie verfahren
NO2011003I1 (no) Dimensk fusjonsprotein bestående av de ligandbindende cfomener av de ekstacellulære deler av human type I interieukm-1 reseptor (IL-1R1) og IL-1 reseptor hjelpeprotein bundet (IL-I-RAcP) bundet i tinje til Fc-delen av humant IgG
IL193886A0 (en) Antibodies that bind to ldcam sequences
TR200100937T2 (tr) Alfa-2/Delta geni
DE69808743T2 (de) Netrinrezeptoren
GR3019849T3 (en) Acute pancreatitis associated protein and means for the diagnosis of acute pancreatitis
EP1005539A4 (en) IKK-ALPHA PROTEINS, NUCLEIC ACIDS AND METHOD
EP0820469A4 (en) IDENTIFICATION, CLEANING AND USE OF LECZYMS AND CARBOHYDRATE LIGANDS
ATE350472T1 (de) Jmy, mit-aktivator für p300/cbp, dafür kodierendenucleinsäure und deren verwendungen
ATE310085T1 (de) Cyclin-e2 proteine und dafür kodierende gene
ATE443761T1 (de) Rtd receptor
TR199900277T2 (tr) Nematodlara ve/veya yaprak bitlerine karsi direnç.
IL157464A0 (en) Zinc finger binding domains for nucleotide sequence ann
DE60119552D1 (de) Isolierte peptide, die an hla-c moleküle binden und deren verwendung
DE69535380D1 (de) Humaner kappa opiatrezeptor, nukleinsäuren und ihre verwendungen
CA2311646A1 (en) Tsa305 gene
DE69733026D1 (de) Cyclin e spezifische konstrukte und komplexe
TW342413B (en) Novel toxins isolated from Bracon Hebetor
DE69932247D1 (de) Menschlisches il-1 epsilon dna und polypeptide
DE59914061D1 (de) Das gen prv-1 und dessen verwendung
ATE213773T1 (de) In apoptosis beteiligte cysteine protease cmh-1 und dns-sequenzen dafür
ATE275207T1 (de) Dna zur abschätzung des progressionspotentials von zervixläsionen
WO2000008178A3 (en) Murine dna molecules encoding polypeptides having kinase functions
ATE104344T1 (de) Gereinigte ubiquitin-hydrolase, diese kodierende dns-sequenzen und ihre verwendung zur gewinnung von polypeptiden.