TR200100354T2 - Monocyclic compounds and formations with NK-2 Antagonist action. - Google Patents

Monocyclic compounds and formations with NK-2 Antagonist action.

Info

Publication number
TR200100354T2
TR200100354T2 TR2001/00354T TR200100354T TR200100354T2 TR 200100354 T2 TR200100354 T2 TR 200100354T2 TR 2001/00354 T TR2001/00354 T TR 2001/00354T TR 200100354 T TR200100354 T TR 200100354T TR 200100354 T2 TR200100354 T2 TR 200100354T2
Authority
TR
Turkey
Prior art keywords
formations
antagonist action
monocyclic compounds
compounds
monocyclic
Prior art date
Application number
TR2001/00354T
Other languages
Turkish (tr)
Inventor
Altamura Maria
Criscuoli Marco
Guidi Antonio
Perrotta Enzo
Alberto Maggi Carlo
Original Assignee
Menarini Ricerche S.P.A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A filed Critical Menarini Ricerche S.P.A
Publication of TR200100354T2 publication Critical patent/TR200100354T2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Formül (I)'in, NK2 alicisinda zit hareketi olan, bilesimleri ve bunlarin farmatik olarak kabul edilen tuzlari tanimlanmaktadir. Yukarida bahsedilen bilesimlerin ve bunlari içeren farmatik preparasyonlarin hazirlanmasi için islemler de ayrica tanimlanmaktadir.The compounds of formula (I) with opposite action in the NK2 receptor and their pharmaceutically acceptable salts are defined. The processes for the preparation of the above-mentioned compositions and the pharmaceutical preparations containing them are also defined.

TR2001/00354T 1998-08-05 1999-07-30 Monocyclic compounds and formations with NK-2 Antagonist action. TR200100354T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998FI000186A IT1304888B1 (en) 1998-08-05 1998-08-05 MONOCYCLIC ACTION COMPOUNDS NK-2 ANTAGONIST AND FORMULATIONS THAT CONTAIN

Publications (1)

Publication Number Publication Date
TR200100354T2 true TR200100354T2 (en) 2001-05-21

Family

ID=11352646

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00354T TR200100354T2 (en) 1998-08-05 1999-07-30 Monocyclic compounds and formations with NK-2 Antagonist action.

Country Status (11)

Country Link
EP (1) EP1102789A1 (en)
JP (1) JP2002522450A (en)
AR (1) AR021751A1 (en)
AU (1) AU5507999A (en)
CA (1) CA2339638A1 (en)
CO (1) CO5080789A1 (en)
IT (1) IT1304888B1 (en)
PE (1) PE20001002A1 (en)
TR (1) TR200100354T2 (en)
TW (1) TW491857B (en)
WO (1) WO2000008046A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1307809B1 (en) * 1999-10-21 2001-11-19 Menarini Ricerche Spa BASIC MONOCYCLIC COMPOUNDS WITH NK-2 ANTAGONIST ACTION, MANUFACTURING PROCESSES AND FORMULATIONS CONTAINING THEM.
HUE026904T2 (en) 2003-04-24 2016-08-29 Incyte Holdings Corp Aza spiro alkane derivatives as inhibitors of metallproteases
UY38485A (en) 2018-11-27 2020-06-30 Novartis Ag CYCLIC TETRAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN / KEXIN TYPE 9 (PCSK9) INHIBITORS, METHOD OF TREATMENT, USE AND PREPARATION

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703034A (en) * 1986-04-28 1987-10-27 Merck & Co., Inc. Novel cyclic tetrapeptide
EP0606222A1 (en) * 1991-08-08 1994-07-20 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Cyclic hexapeptides as tachyquinin antagonists, their preparation and pharmaceutical compositions thereof
DK0528312T3 (en) * 1991-08-13 1997-12-29 Takeda Chemical Industries Ltd Cyclic peptides and their use
IT1277835B1 (en) * 1995-03-13 1997-11-12 Menarini Farma Ind BICYCLE COMPOUNDS, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS
IT1291776B1 (en) * 1997-02-07 1999-01-21 Menarini Ricerche Spa MONOCYCLIC COMPOUNDS WITH FOUR BIFUNCTIONAL RESIDUES, HAVING NK-2 ANTAGONIST ACTION

Also Published As

Publication number Publication date
ITFI980186A1 (en) 2000-02-05
CA2339638A1 (en) 2000-02-17
TW491857B (en) 2002-06-21
WO2000008046A1 (en) 2000-02-17
CO5080789A1 (en) 2001-09-25
JP2002522450A (en) 2002-07-23
PE20001002A1 (en) 2000-10-16
IT1304888B1 (en) 2001-04-05
AR021751A1 (en) 2002-08-07
EP1102789A1 (en) 2001-05-30
AU5507999A (en) 2000-02-28

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