TR199801776T2 - Trypanosomatid t�rlerine ba����kl�k - Google Patents
Trypanosomatid t�rlerine ba����kl�kInfo
- Publication number
- TR199801776T2 TR199801776T2 TR1998/01776T TR9801776T TR199801776T2 TR 199801776 T2 TR199801776 T2 TR 199801776T2 TR 1998/01776 T TR1998/01776 T TR 1998/01776T TR 9801776 T TR9801776 T TR 9801776T TR 199801776 T2 TR199801776 T2 TR 199801776T2
- Authority
- TR
- Turkey
- Prior art keywords
- histones
- histone
- adjuvants
- isolated
- genes
- Prior art date
Links
- 108010033040 Histones Proteins 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 102000006947 Histones Human genes 0.000 abstract 3
- 239000002671 adjuvant Substances 0.000 abstract 2
- 101710194807 Protective antigen Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bu bulus, tripanosomatik enfeksiyona karsi koruyucu bir antijen olarak kullanilmak üzere temelde yalitilmis bir sekilde bulunan tripanosomatid histonlari ile ilgilidir. Bu histonlar iliskin parazitten yalitilabilir ya da rekombinant DNA teknikleri ile üretilebilir. Daha sonra kullanilmak üzere bu bulus ayrica histonlari kodlayan genleri ve baska nükleik asitler gibi bu genlerin türevlerini ve peptidler ve proteinler gibi gen ürünlerini de sunmaktadir. Bu bulus ayrica bilinen yardimci maddeler ve/veya ek maddeleri, en az bir histon ve bir histonu kodlayan bir geni ya da onun bir türevini içeren teshis testleri, farmasötik kompozisyonlari va asilari da sunmaktadirThis invention relates to the essentially isolated trypanosomatide histones for use as a protective antigen against trypanosomatic infection. These histones can be isolated from the associated parasite or can be produced by recombinant DNA techniques. To be used later, this invention also provides genes encoding histones and derivatives of these genes, such as other nucleic acids, and gene products such as peptides and proteins. This invention also provides diagnostic assays, pharmaceutical compositions, and vaccines comprising known adjuvants and / or adjuvants, at least one histone and a gene encoding a histone, or a derivative thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96200665 | 1996-03-12 | ||
| EP96201343 | 1996-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199801776T2 true TR199801776T2 (en) | 1998-12-21 |
Family
ID=26142593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/01776T TR199801776T2 (en) | 1996-03-12 | 1997-03-12 | Trypanosomatid t�rlerine ba����kl�k |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0896623A1 (en) |
| JP (1) | JP2000507098A (en) |
| CN (1) | CN1216584A (en) |
| AU (1) | AU733720B2 (en) |
| BR (1) | BR9708188A (en) |
| CA (1) | CA2248684A1 (en) |
| IL (1) | IL126145A0 (en) |
| MA (1) | MA25182A1 (en) |
| NZ (1) | NZ331889A (en) |
| TN (1) | TNSN97045A1 (en) |
| TR (1) | TR199801776T2 (en) |
| WO (1) | WO1997033999A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1687023B1 (en) * | 2003-11-05 | 2012-10-03 | C.B.F. Leti, S.L. Unipersonal | Use of specific histones for the treatment of parasitic diseases |
| FR2952382B1 (en) * | 2009-11-10 | 2011-11-25 | Univ Victor Segalen Bordeaux 2 | VACCINES AND DIAGNOSES AGAINST AFRICAN ANIMAL TRYPANOSOMOSES |
| BRPI1003744B1 (en) * | 2010-06-08 | 2021-10-26 | Universidade Federal De Ouro Preto | RECOMBINANT E-NTPDASES, USE IN THE PRODUCTION OF DIAGNOSTIC KIT FOR ANTIBODY DETECTION IN LEISHMANIASIS CAUSED BY SPECIES OF THE GENUS LEISHMANIA |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8722741D0 (en) * | 1987-09-28 | 1987-11-04 | Hoffmann La Roche | Induction of cytotoxic t cell response |
-
1997
- 1997-03-11 TN TNTNSN97045A patent/TNSN97045A1/en unknown
- 1997-03-11 MA MA24516A patent/MA25182A1/en unknown
- 1997-03-12 JP JP9532298A patent/JP2000507098A/en not_active Withdrawn
- 1997-03-12 WO PCT/EP1997/001289 patent/WO1997033999A1/en not_active Application Discontinuation
- 1997-03-12 EP EP97908233A patent/EP0896623A1/en not_active Withdrawn
- 1997-03-12 AU AU20272/97A patent/AU733720B2/en not_active Ceased
- 1997-03-12 IL IL12614597A patent/IL126145A0/en unknown
- 1997-03-12 NZ NZ331889A patent/NZ331889A/en unknown
- 1997-03-12 TR TR1998/01776T patent/TR199801776T2/en unknown
- 1997-03-12 CA CA002248684A patent/CA2248684A1/en not_active Abandoned
- 1997-03-12 CN CN97193835A patent/CN1216584A/en active Pending
- 1997-03-12 BR BR9708188-4A patent/BR9708188A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0896623A1 (en) | 1999-02-17 |
| MA25182A1 (en) | 2001-07-02 |
| AU2027297A (en) | 1997-10-01 |
| CA2248684A1 (en) | 1997-09-18 |
| IL126145A0 (en) | 1999-05-09 |
| AU733720B2 (en) | 2001-05-24 |
| TNSN97045A1 (en) | 2005-03-15 |
| JP2000507098A (en) | 2000-06-13 |
| BR9708188A (en) | 2000-01-18 |
| NZ331889A (en) | 2000-12-22 |
| CN1216584A (en) | 1999-05-12 |
| WO1997033999A1 (en) | 1997-09-18 |
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