TNSN97045A1 - HISTONES OF TRYPANOSOMATIDES, GENES AND DERIVATIVES OF GENES ENCODING THEM, DNA CONSTRUCTION, VECTOR, HOST ORGANISMS, TESTS AND VACCINES THEREOF, AND THEIR USE. - Google Patents
HISTONES OF TRYPANOSOMATIDES, GENES AND DERIVATIVES OF GENES ENCODING THEM, DNA CONSTRUCTION, VECTOR, HOST ORGANISMS, TESTS AND VACCINES THEREOF, AND THEIR USE.Info
- Publication number
- TNSN97045A1 TNSN97045A1 TNTNSN97045A TNSN97045A TNSN97045A1 TN SN97045 A1 TNSN97045 A1 TN SN97045A1 TN TNSN97045 A TNTNSN97045 A TN TNSN97045A TN SN97045 A TNSN97045 A TN SN97045A TN SN97045 A1 TNSN97045 A1 TN SN97045A1
- Authority
- TN
- Tunisia
- Prior art keywords
- genes
- histones
- trypanosomatides
- vaccines
- derivatives
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 8
- 108010033040 Histones Proteins 0.000 title abstract 6
- 102000006947 Histones Human genes 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000010276 construction Methods 0.000 title 1
- 238000012360 testing method Methods 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'INVENTION CONCERNE DES HISTONES DE TRYPANOSOMATIDES SOUS FORME SENSIBLEMENT ISOLEES DESTINEES A ETRE UTILISEES COMME ANTIGENES PROTECTEURS CONTRE LES INFECTIONS A TRYPANOSOMATIDES, LESQUELLES HISTONES PEUVENT ETRE ISOLEES A PARTIR DU PARASITE CORRESPONDANT OU PRODUITES PAR DES TECHNIQUES D'ADN RECOMBINE, AUQUEL CAS L'INVENTION CONCERNE EGALEMENT DES GENES CODANT DES HISTONES, NOTAMMENT DES GENES QUI S'HYDRIDENT A UNE PARTIE AU MOINS DE LA SEQUENCE NUCLEOTIDIQUE REPRESENTEE SUR LA FIGURE 6A, ET DES DERIVES DES GENES TELS QUE D'AUTRES ACIDES NUCLEIQUES ET DES PRODUITS GENIQUES TES QUE DES PEPTIDES ET DES PROTEINES, ET EGALEMENT DES TESTS DE DIAGNOSTIC, DES COMPOSITIONS PHARMACEUTIQUES ET DES VACCINS COMPRENANT LES EXCIPIENTS ET/OU ADJUVANTS USUELS ET AU MOINS UNE HISTONE, UN GENE CODANT UNE HISTONE OU UN DERIVE DE CELUI-CI.THE INVENTION CONCERNS HISTONES OF TRYPANOSOMATIDES IN SUBSTANTIALLY ISOLATED FORM FOR USE AS PROTECTIVE ANTIGENS AGAINST TRYPANOSOMATIDE INFECTIONS, WHICH HISTONES MAY BE ISOLATED FROM PARASINE BY PARASINE. ALSO CONCERNS GENES ENCODING HISTONES, IN PARTICULAR GENES WHICH HYDRIZE TO A PARTY AT LEAST OF THE NUCLEOTIDE SEQUENCE REPRESENTED IN FIGURE 6A, AND DERIVATIVES OF GENES SUCH AS OTHER NUCLEIC ACIDS AND GENE PRODUCTS SUCH AS PEPTIDES AND PROTEINS, AND ALSO DIAGNOSTIC TESTS, PHARMACEUTICAL COMPOSITIONS AND VACCINES COMPRISING USUAL EXCIPIENTS AND / OR ADJUVANTS AND AT LEAST ONE HISTONE, A GENE ENCODING A HISTONE OR A DERIVATIVE THEREOF.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96200665 | 1996-03-12 | ||
| EP96201343 | 1996-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN97045A1 true TNSN97045A1 (en) | 2005-03-15 |
Family
ID=26142593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN97045A TNSN97045A1 (en) | 1996-03-12 | 1997-03-11 | HISTONES OF TRYPANOSOMATIDES, GENES AND DERIVATIVES OF GENES ENCODING THEM, DNA CONSTRUCTION, VECTOR, HOST ORGANISMS, TESTS AND VACCINES THEREOF, AND THEIR USE. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0896623A1 (en) |
| JP (1) | JP2000507098A (en) |
| CN (1) | CN1216584A (en) |
| AU (1) | AU733720B2 (en) |
| BR (1) | BR9708188A (en) |
| CA (1) | CA2248684A1 (en) |
| IL (1) | IL126145A0 (en) |
| MA (1) | MA25182A1 (en) |
| NZ (1) | NZ331889A (en) |
| TN (1) | TNSN97045A1 (en) |
| TR (1) | TR199801776T2 (en) |
| WO (1) | WO1997033999A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2380710C2 (en) * | 2003-11-05 | 2010-01-27 | К.Б.Ф. Лети, С.Л. Юниперсонал | Treatment, diagnostics or prevention of leishmaniasis caused by various types of parasites, except that one used to produce histones, with using all of four histones h2a, h2b, h3 and h4, recovered from leishmania infantum with using vector containing nucleotides coding specified histones |
| FR2952382B1 (en) * | 2009-11-10 | 2011-11-25 | Univ Victor Segalen Bordeaux 2 | VACCINES AND DIAGNOSES AGAINST AFRICAN ANIMAL TRYPANOSOMOSES |
| BRPI1003744B1 (en) * | 2010-06-08 | 2021-10-26 | Universidade Federal De Ouro Preto | RECOMBINANT E-NTPDASES, USE IN THE PRODUCTION OF DIAGNOSTIC KIT FOR ANTIBODY DETECTION IN LEISHMANIASIS CAUSED BY SPECIES OF THE GENUS LEISHMANIA |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8722741D0 (en) * | 1987-09-28 | 1987-11-04 | Hoffmann La Roche | Induction of cytotoxic t cell response |
-
1997
- 1997-03-11 TN TNTNSN97045A patent/TNSN97045A1/en unknown
- 1997-03-11 MA MA24516A patent/MA25182A1/en unknown
- 1997-03-12 WO PCT/EP1997/001289 patent/WO1997033999A1/en not_active Application Discontinuation
- 1997-03-12 IL IL12614597A patent/IL126145A0/en unknown
- 1997-03-12 TR TR1998/01776T patent/TR199801776T2/en unknown
- 1997-03-12 BR BR9708188-4A patent/BR9708188A/en not_active IP Right Cessation
- 1997-03-12 CN CN97193835A patent/CN1216584A/en active Pending
- 1997-03-12 AU AU20272/97A patent/AU733720B2/en not_active Ceased
- 1997-03-12 NZ NZ331889A patent/NZ331889A/en unknown
- 1997-03-12 CA CA002248684A patent/CA2248684A1/en not_active Abandoned
- 1997-03-12 EP EP97908233A patent/EP0896623A1/en not_active Withdrawn
- 1997-03-12 JP JP9532298A patent/JP2000507098A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997033999A1 (en) | 1997-09-18 |
| AU733720B2 (en) | 2001-05-24 |
| CA2248684A1 (en) | 1997-09-18 |
| CN1216584A (en) | 1999-05-12 |
| IL126145A0 (en) | 1999-05-09 |
| NZ331889A (en) | 2000-12-22 |
| TR199801776T2 (en) | 1998-12-21 |
| AU2027297A (en) | 1997-10-01 |
| EP0896623A1 (en) | 1999-02-17 |
| BR9708188A (en) | 2000-01-18 |
| MA25182A1 (en) | 2001-07-02 |
| JP2000507098A (en) | 2000-06-13 |
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