TNSN98138A1 - NOVEL STIMULATING BENZAMIDE DERIVATIVES OF HIGH AND LOW GASTROINTESTINAL MOTORITY - Google Patents

NOVEL STIMULATING BENZAMIDE DERIVATIVES OF HIGH AND LOW GASTROINTESTINAL MOTORITY

Info

Publication number
TNSN98138A1
TNSN98138A1 TNTNSN98138A TNSN98138A TNSN98138A1 TN SN98138 A1 TNSN98138 A1 TN SN98138A1 TN TNSN98138 A TNTNSN98138 A TN TNSN98138A TN SN98138 A TNSN98138 A TN SN98138A TN SN98138 A1 TNSN98138 A1 TN SN98138A1
Authority
TN
Tunisia
Prior art keywords
motority
benzamide derivatives
low gastrointestinal
stimulating
novel
Prior art date
Application number
TNTNSN98138A
Other languages
French (fr)
Inventor
Thierry Bouyssou
Helene Christinaki
Olivier Boucheix
Serge Boisa
Christian Jeanpetit
Original Assignee
Logeais Labor Jacques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Logeais Labor Jacques filed Critical Logeais Labor Jacques
Publication of TNSN98138A1 publication Critical patent/TNSN98138A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES DE FORMULE GENERALE (I) SUIVANTE :DANS LAQUELLE n = 1 OU 2, R1 EST UN GROUPE ALKYLE OU CYCLOALKYLE, R2 ET R3 REPRESENTENT H, OH, OU UN GROUPE CYCLOALKYLE. L'INVENTION CONCERNE EGALEMENT LES COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES, ET LEUR UTILISATION DANS LE CADRE DU TRAITEMENT DES DYSFONCTIONNEMENTS DU TUBE DIGESTIF HAUT ET BASTHE INVENTION RELATES TO COMPOUNDS OF THE FOLLOWING GENERAL FORMULA (I): IN WHICH n = 1 OR 2, R1 IS AN ALKYL OR CYCLOALKYL GROUP, R2 AND R3 REPRESENT H, OH, OR A CYCLOALKYLE GROUP. THE INVENTION ALSO CONCERNS THE PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, AND THEIR USE IN THE FRAMEWORK OF THE TREATMENT OF HIGH AND LOW DIGESTIVE TUBE DYSFUNCTIONS

TNTNSN98138A 1997-07-25 1998-07-15 NOVEL STIMULATING BENZAMIDE DERIVATIVES OF HIGH AND LOW GASTROINTESTINAL MOTORITY TNSN98138A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709477A FR2766484B1 (en) 1997-07-25 1997-07-25 NOVEL STIMULATING BENZAMIDE DERIVATIVES OF HIGH AND LOW GASTROINTESTINAL MOTORITY

Publications (1)

Publication Number Publication Date
TNSN98138A1 true TNSN98138A1 (en) 2005-03-15

Family

ID=9509623

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98138A TNSN98138A1 (en) 1997-07-25 1998-07-15 NOVEL STIMULATING BENZAMIDE DERIVATIVES OF HIGH AND LOW GASTROINTESTINAL MOTORITY

Country Status (8)

Country Link
EP (1) EP0998458A1 (en)
AR (1) AR014900A1 (en)
AU (1) AU8867898A (en)
CO (1) CO4990994A1 (en)
FR (1) FR2766484B1 (en)
TN (1) TNSN98138A1 (en)
WO (1) WO1999005106A1 (en)
ZA (1) ZA986633B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620543A (en) *
GB1015921A (en) * 1961-10-06 1966-01-05 Benger Lab Ltd Benzamides
AR216043A1 (en) * 1974-03-21 1979-11-30 Anphar Sa PROCEDURE FOR THE PREPARATION OF 1-BENZOYLAMINE-4-PIPERIDINE DERIVATIVES AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS
EP0222533A1 (en) * 1985-10-25 1987-05-20 The Upjohn Company Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants
FR2674849B1 (en) * 1991-04-02 1994-12-23 Logeais Labor Jacques NOVEL N-CYCLOHEXYL BENZAMIDES OR THIOBENZAMIDES DERIVATIVES, THEIR PREPARATIONS AND THEIR THERAPEUTIC APPLICATIONS.
NZ243993A (en) * 1991-08-20 1994-10-26 Smithkline Beecham Plc Pharmaceutical compositions having 5-ht4 receptor antagonist activity and selected compounds having such activity
WO1995025100A1 (en) * 1994-03-14 1995-09-21 Sanofi Use of 4-amino-5-chloro-2-methoxybenzoic esters as 5-ht4 agonists
FR2735693B1 (en) * 1995-06-23 1997-09-26 Logeais Labor Jacques NEW THERAPEUTIC APPLICATIONS OF N-CYCLOHEXYL BENZAMIDES

Also Published As

Publication number Publication date
WO1999005106A1 (en) 1999-02-04
CO4990994A1 (en) 2000-12-26
EP0998458A1 (en) 2000-05-10
AR014900A1 (en) 2001-04-11
WO1999005106A8 (en) 1999-04-15
FR2766484B1 (en) 1999-09-17
FR2766484A1 (en) 1999-01-29
AU8867898A (en) 1999-02-16
ZA986633B (en) 1999-06-15

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