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Application filed by Oklahoma Med Res Found, Univ Kentucky Res FoundfiledCriticalOklahoma Med Res Found
Priority to TNSN95067priorityCriticalpatent/TNSN95067A1/en
Publication of TNSN95067A1publicationCriticalpatent/TNSN95067A1/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
2,4-DISULFONYLE -PHENYLE-TERTIOBUTYLE NITRONE ET SES SELS PHARMACEUTIQUEMENT ACCEPTABLES SONT REVELES. CES CORPS SONT UTILES COMME AGENTS PHARMACEUTIQUES POUR ADMINISTRATION PAR VOIE BUCCALE OU PARENTERALE, PAR EXEMPLE L'ADMINISTRATION PAR INTRAVEINEUSE A DES PATIENTS SOUFFRANT D'OXYDATION AIGUE DU SYSTEME NERVEUX CENTRAL QUI SE PRODUIT A LA SUITE D'UN ACCIDENT VASCULAIRE CEREBRAL OU D'OXYDATION PROGRESSIVE DU SYSTEME NERNEUX CENTRAL QUI PEUT SE CARACTERISER PAR LA PERTE PROGRESSIVE DE FONCTION DU SYSTEME NERVEUX CENTRAL. LES CORPS SONT AUSSI UTILISES POUR AMELIORER LES EFFETS SECONDAIRES DE LESION OXYDATIVE PROVOQUANT DES TRAITEMENTS ANTINEOPLASTIQUES2,4-DISULFONYL -PHENYL-TERTIOBUTYL NITRONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS ARE REVEALED. THESE BODIES ARE USEFUL AS PHARMACEUTICAL AGENTS FOR ORAL OR PARENTAL ADMINISTRATION, FOR EXAMPLE ADMINISTRATION BY INTRAVENOUS PATIENTS WITH ACUTE OXIDATION OF THE CENTRAL NERVOUS SYSTEM WHICH HAS OCCURRED FROM A VASCULAR OR ACCIDULAR ACCIDENT. PROGRESSIVE OF THE CENTRAL NERVOUS SYSTEM WHICH MAY BE CHARACTERIZED BY THE PROGRESSIVE LOSS OF FUNCTION OF THE CENTRAL NERVOUS SYSTEM. BODIES ARE ALSO USED TO IMPROVE SIDE EFFECTS OF OXIDATIVE LESION CAUSING ANTINEOPLASTIC TREATMENTS
TNSN950671995-06-191995-06-19
2,4-DISULFONYLE PHENYLBUTYLE NITRONE, ITS SALTS, AND THEIR USE AS PHARMACEUTICALS
TNSN95067A1
(en)
Pharmaceutically acceptable salt compound Pharmaceutical composition and processes for treating a patient who has suffered a stroke and suffering from a condition of progressive loss of central nervous system function and to improve the side effects caused in a patient by antineoplastic treatment of the disease it produces oxidative damage
TRANS-PIPERAZINE-1-YL-SPIRO (CYCLOHEXANE-1, 1'- ISOBENZOFURANNE) DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM