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Priority claimed from GB898927913Aexternal-prioritypatent/GB8927913D0/en
Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Publication of TNSN90147A1publicationCriticalpatent/TNSN90147A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
LES COMPOSES DE FORMULE GENERALE (I) DANS LAQUELLE R REPRESENTE UN BENZYLOXYCARBONYLE OU UN 2-QUINOLEYLCARBONYLE, ET LEURS SELS D'ADDITION D'ACIDES PHARMACEUTIQUEMENT ACCEPTABLES INHIBENT LES PROTEASES D'ORIGINE VIRALE ET PEUVENT ETRE MEDICAMENTS POUR LE TRAITEMENT OU LA PROPHYLAXIE DES INFECTIONS VIRALES. ON PEUT LES PREPARER SELON DES PROCEDES GENERALEMENT CONNUSTHE COMPOUNDS OF GENERAL FORMULA (I) IN WHICH R REPRESENTS A BENZYLOXYCARBONYL OR A 2-QUINOLEYLCARBONYL, AND THEIR ADDED SALTS OF PHARMACEUTICALLY ACCEPTABLE ACIDS INHIBIT VIRAL ORIGIN PROTEASES, WHICH MAY BE HARMFUL OR INJURIOUS DRUGS VIRALS. CAN BE PREPARED ACCORDING TO GENERALLY KNOWN PROCESSES
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids, their salts, pharmaceutical preparations containing the derivatives or salts and their preparation.
To inhibit the release and/or synthesis of β-amyloid peptide using N-(aryl/heteoaryl) amino acid derivatives, pharmaceutical compositions containing them, and such compounds for methods.
GONADOLIBERIN DERIVATIVES CONTAINING AROMATIC AMINOCARBOXYLIC ACID IN POSITION 6, PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING THE SAME.