TNSN90053A1 - PROCESS FOR OBTAINING NEW 17/21 ALKYL DERIVATIVES OF 19- NOR PROGESTERONE - Google Patents

PROCESS FOR OBTAINING NEW 17/21 ALKYL DERIVATIVES OF 19- NOR PROGESTERONE

Info

Publication number
TNSN90053A1
TNSN90053A1 TNTNSN90053A TNSN90053A TNSN90053A1 TN SN90053 A1 TNSN90053 A1 TN SN90053A1 TN TNSN90053 A TNTNSN90053 A TN TNSN90053A TN SN90053 A TNSN90053 A TN SN90053A TN SN90053 A1 TNSN90053 A1 TN SN90053A1
Authority
TN
Tunisia
Prior art keywords
progesterone
alkyl derivatives
obtaining new
carbon atoms
branched chain
Prior art date
Application number
TNTNSN90053A
Other languages
French (fr)
Inventor
Claude Tchernatinsky
Nejib Mohamed Nasraoui
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of TNSN90053A1 publication Critical patent/TNSN90053A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'INVENTION SE RAPPORTE AU DOMAINE DE LA CHIMIE ET PLUS PARTICULIEREMENT A CELUI DE LA CHIMIE THERAPEUTIQUE. ELLE A PARTICULIEREMENT POUR OBJET LES 6-METHYL 19-NOR PREGNA 4,6-DIENES 17α, ET EVENTUELLEMENT, 21- ALCOYLES DE FORMULE GENERALE I (I) DANS LAQUELLE R" ET R' IDENTIQUES OU DIFFERENTS REPRESENTENT DE L'HYDROGENE OU UN RADICAL ALCOYLE AYANT DE 1 A 3 ATOMES DE CARBONE EN CHAINE DROITE OU RAMIFIEE ET R1 REPRESENTE UN RADICAL ALCOYLE INFERIEUR AYANT DE 1 A 6 ATOMES DE CARBONE, EN CHAINE DROITE OU RAMIFIEE ELLE A EGALEMENT POUR OBJET UN PROCEDE D'OBTENTION DES COMPOSES DE FORMULE GENERALE I ET LEUR EMPLOI COMME PRINCIPES ACTIFS DE MEDICAMENTS.THE INVENTION RELATES TO THE FIELD OF CHEMISTRY AND MORE PARTICULARLY TO THAT OF THERAPEUTIC CHEMISTRY. IT PARTICULARLY FOR OBJECT THE 6-METHYL 19-NOR PREGNA 4,6-DIENES 17α, AND POSSIBLY, 21- ALCOYLS OF GENERAL FORMULA I (I) IN WHICH R "AND R 'IDENTIQUES OR DIFFERENTS REPRESENT HYDROGEN OR A ALKYL RADICAL HAVING 1 TO 3 CARBON ATOMS IN A RIGHT OR BRANCHED CHAIN AND R1 REPRESENTS A LOWER ALKYL RADIUS HAVING 1 TO 6 CARBON ATOMS, IN A RIGHT OR BRANCHED CHAIN, ALSO FOR THE PURPOSE OF A PROCESS FOR OBTAINING THE FORMULA COMPOUNDS GENERAL I AND THEIR USE AS ACTIVE INGREDIENTS OF MEDICINES.

TNTNSN90053A 1989-04-13 1990-04-13 PROCESS FOR OBTAINING NEW 17/21 ALKYL DERIVATIVES OF 19- NOR PROGESTERONE TNSN90053A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8904910A FR2645864B1 (en) 1989-04-13 1989-04-13 NOVEL 17/21 ALKYL DERIVATIVES OF 19-NOR PROGESTERONE, PROCESSES FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Publications (1)

Publication Number Publication Date
TNSN90053A1 true TNSN90053A1 (en) 1991-03-05

Family

ID=9380699

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN90053A TNSN90053A1 (en) 1989-04-13 1990-04-13 PROCESS FOR OBTAINING NEW 17/21 ALKYL DERIVATIVES OF 19- NOR PROGESTERONE

Country Status (12)

Country Link
EP (1) EP0437552A1 (en)
JP (1) JPH04500523A (en)
KR (1) KR920700219A (en)
AU (1) AU635739B2 (en)
FI (1) FI906116A0 (en)
FR (1) FR2645864B1 (en)
HU (1) HU208152B (en)
NO (1) NO174393C (en)
OA (1) OA09632A (en)
RU (1) RU1836379C (en)
TN (1) TNSN90053A1 (en)
WO (1) WO1990012027A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2675047B1 (en) * 1991-04-09 1995-05-12 Theramex NOVEL ANTI-GLAUCOMATORY PHARMACEUTICAL COMPOSITIONS AND THEIR PROCESS FOR OBTAINING SAME.
KR100249555B1 (en) * 1991-06-18 2000-04-01 루게쥐농 프랑스와 Ocular compositions containing steroids and their use in treating glaucoma
FR2679236B1 (en) * 1991-07-18 1997-01-24 Theramex NOVEL STEROUIDES SUBSTITUTED IN POSITION 6, PROCESSES FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
HU231125B1 (en) 2016-12-16 2020-12-28 Richter Gedeon Nyrt. Industrial process for the preparation of nomegestrol acetate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361744A (en) * 1962-07-18 1968-01-02 American Cyanamid Co Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same
FR2077877B1 (en) * 1970-02-20 1974-02-01 Roussel Uclaf
FR2552766B1 (en) * 1983-10-04 1987-06-26 Theramex NEW PROCESS FOR THE PREPARATION OF DERIVATIVES FROM THE 17 A-HYDROXY 19-NOR PROGESTERONE SERIES
AU624096B2 (en) * 1987-10-27 1992-06-04 Laboratoire Theramex S.A. Derivatives of 19-norprogesterone, their preparation and their use

Also Published As

Publication number Publication date
AU5552590A (en) 1990-11-05
NO905344L (en) 1991-02-01
OA09632A (en) 1993-04-30
JPH04500523A (en) 1992-01-30
RU1836379C (en) 1993-08-23
KR920700219A (en) 1992-02-19
NO905344D0 (en) 1990-12-11
HU208152B (en) 1993-08-30
HUT56579A (en) 1991-09-30
FR2645864B1 (en) 1991-07-12
NO174393B (en) 1994-01-17
FI906116A0 (en) 1990-12-12
NO174393C (en) 1994-04-27
HU904373D0 (en) 1991-06-28
AU635739B2 (en) 1993-04-01
FR2645864A1 (en) 1990-10-19
WO1990012027A1 (en) 1990-10-18
EP0437552A1 (en) 1991-07-24

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