TNSN00178A1 - Fused pyrrolecaboxamides; a new class of gaba brain receptor ligands - Google Patents

Fused pyrrolecaboxamides; a new class of gaba brain receptor ligands

Info

Publication number
TNSN00178A1
TNSN00178A1 TNTNSN00178A TNSN00178A TNSN00178A1 TN SN00178 A1 TNSN00178 A1 TN SN00178A1 TN TNSN00178 A TNTNSN00178 A TN TNSN00178A TN SN00178 A TNSN00178 A TN SN00178A TN SN00178 A1 TNSN00178 A1 TN SN00178A1
Authority
TN
Tunisia
Prior art keywords
gaba
pyrrolecaboxamides
fused
compounds
new class
Prior art date
Application number
TNTNSN00178A
Other languages
French (fr)
Inventor
Hutchison Alan
Albaugh Pamela
Shaw Kenneth
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of TNSN00178A1 publication Critical patent/TNSN00178A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

SUBSTITUED PYRROLECARBOXAMIDE COMPOUNDS ARE DISCLOSED. THESE COMPOUNDS ARE HIGHLY SELECTIVE AGONISTS, ANTAGONISTS OR INVERSE AGONISTS FOR GABA BRAIN RECEPTORS OR PRODRUGS OF AGONISTS, ANTAGONISTS OR INVERSE AGONISTS FOR GABA BRAIN RECEPTORS AND ARE THEREFORE USEFUL IN THE DIAGNOSIS AND TREATMENT OF ANXIETY, DEPRESSION, ALZHEIMER'S DEMENTIA, SLEEP AND SEIZURE DISORDERS, OVERDOSE WITH BENZODIAZEPINE DRUGS AND FOR ENHANCEMENT OF MEMORY. PHARMACEUTICAL COMPOSITIONS, INCLUDING PACKAGED PHARMACEUTICAL COMPOSITIONS, ARE FURTHER PROVIDED. COMPOUNDS OF THE INVENTION ARE ALSO USEFUL AS PROBES FOR THE LOCALIZATION OF GABA RECEPTORS IN TISSUE SAMPLES.
TNTNSN00178A 1999-08-31 2000-08-30 Fused pyrrolecaboxamides; a new class of gaba brain receptor ligands TNSN00178A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38731199A 1999-08-31 1999-08-31

Publications (1)

Publication Number Publication Date
TNSN00178A1 true TNSN00178A1 (en) 2002-05-30

Family

ID=27805344

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN00178A TNSN00178A1 (en) 1999-08-31 2000-08-30 Fused pyrrolecaboxamides; a new class of gaba brain receptor ligands

Country Status (10)

Country Link
AR (1) AR040397A1 (en)
CO (1) CO5180633A1 (en)
EC (1) ECSP003641A (en)
GT (1) GT200000146A (en)
PA (1) PA8501901A1 (en)
PE (1) PE20010533A1 (en)
SV (1) SV2002000161A (en)
TN (1) TNSN00178A1 (en)
UY (1) UY26322A1 (en)
ZA (1) ZA200201649B (en)

Also Published As

Publication number Publication date
PE20010533A1 (en) 2001-05-01
PA8501901A1 (en) 2002-12-11
SV2002000161A (en) 2002-09-04
AR040397A1 (en) 2005-04-06
ECSP003641A (en) 2002-03-25
ZA200201649B (en) 2003-05-28
CO5180633A1 (en) 2002-07-30
UY26322A1 (en) 2001-06-29
GT200000146A (en) 2002-02-22

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