TN2013000442A1 - FORMULATION FOR ANTI-α4β7 ANTIBODY - Google Patents
FORMULATION FOR ANTI-α4β7 ANTIBODYInfo
- Publication number
- TN2013000442A1 TN2013000442A1 TNP2013000442A TN2013000442A TN2013000442A1 TN 2013000442 A1 TN2013000442 A1 TN 2013000442A1 TN P2013000442 A TNP2013000442 A TN P2013000442A TN 2013000442 A TN2013000442 A TN 2013000442A TN 2013000442 A1 TN2013000442 A1 TN 2013000442A1
- Authority
- TN
- Tunisia
- Prior art keywords
- antibody
- a4ss7
- formulations
- formulation
- vivo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Abstract
Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-a4ss7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-a4ss7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4ss7 antibody in vivo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261585859P | 2012-01-12 | 2012-01-12 | |
PCT/US2012/036072 WO2012151248A2 (en) | 2011-05-02 | 2012-05-02 | FORMULATION FOR ANTI-α4β7 ANTIBODY |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2013000442A1 true TN2013000442A1 (en) | 2015-03-30 |
Family
ID=54360587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2013000442A TN2013000442A1 (en) | 2012-01-12 | 2013-10-29 | FORMULATION FOR ANTI-α4β7 ANTIBODY |
Country Status (2)
Country | Link |
---|---|
EA (2) | EA034583B1 (en) |
TN (1) | TN2013000442A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4041761A4 (en) * | 2019-10-11 | 2023-10-25 | Dr. Reddy's Laboratories Limited | Stable formulation of integrin antibody |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7147851B1 (en) * | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
US20010046496A1 (en) * | 2000-04-14 | 2001-11-29 | Brettman Lee R. | Method of administering an antibody |
CA2629147A1 (en) * | 2005-11-17 | 2007-05-31 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with .alpha.4.beta.7 integrin |
-
2012
- 2012-05-02 EA EA201892377A patent/EA034583B1/en not_active IP Right Cessation
- 2012-05-02 EA EA201992881A patent/EA201992881A3/en unknown
-
2013
- 2013-10-29 TN TNP2013000442A patent/TN2013000442A1/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4041761A4 (en) * | 2019-10-11 | 2023-10-25 | Dr. Reddy's Laboratories Limited | Stable formulation of integrin antibody |
Also Published As
Publication number | Publication date |
---|---|
EA201992881A2 (en) | 2020-09-30 |
EA201992881A3 (en) | 2020-12-30 |
EA034583B1 (en) | 2020-02-21 |
EA201892377A1 (en) | 2019-03-29 |
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