TH97797B - Pharmaceutical preparations for oral administration with controlled release of the active ingredient in the small intestine. And methods for its production - Google Patents
Pharmaceutical preparations for oral administration with controlled release of the active ingredient in the small intestine. And methods for its productionInfo
- Publication number
- TH97797B TH97797B TH701003448A TH0701003448A TH97797B TH 97797 B TH97797 B TH 97797B TH 701003448 A TH701003448 A TH 701003448A TH 0701003448 A TH0701003448 A TH 0701003448A TH 97797 B TH97797 B TH 97797B
- Authority
- TH
- Thailand
- Prior art keywords
- active ingredient
- small intestine
- pharmaceutical preparations
- controlled release
- methods
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title claims abstract 4
- 239000000825 pharmaceutical preparation Substances 0.000 title claims abstract 4
- 238000013270 controlled release Methods 0.000 title claims abstract 3
- 210000000813 small intestine Anatomy 0.000 title claims abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 claims abstract 6
- 238000009792 diffusion process Methods 0.000 claims abstract 2
- 230000035699 permeability Effects 0.000 claims abstract 2
- 239000010410 layer Substances 0.000 claims 3
- 239000011247 coating layer Substances 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000007423 decrease Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้อธิบายสารเตรียมทางเภสัชกรรมใดๆ สำหรับการใช้ยาทางปาก ที่มีการปลด ปล่อยแบบควบคุมของสารออกฤทธิ์ ในลำไส้เล็ก, บนพื้นฐานของตัวนำสารออกฤทธิ์ที่มีสารออกฤทธิ์ อย่างน้อยที่สุดหนึ่งชนิด ซึ่งให้ไว้พร้อมกับชั้นภายในเพื่อควบคุมการปลดปล่อยสารออกฤทธิ์ และมี ชั้นเคลือบที่ทนต่อภาวะในกระเพาะอาหารที่เคลือบอยู่บนนั้น, ซึ่งมีลักษณะเฉพาะคือ ชั้นภายในถูกทำ ให้เกิดจากชั้นแพร่อย่างน้อยสองชั้นซึ่งความสามารถในการซึมผ่านสำหรับสารออกฤทธิ์ที่แพร่ลดลง จากภายในไปยังภายนอก และวิธีสำหรับการผลิตสารเหล่านี้ This invention describes any pharmaceutical preparation. For oral administration with a controlled release of the active substance in the small intestine, on the basis of the active ingredient-containing agent. At least one of a kind It is provided with an inner layer to regulate the release of the active substance and has a gastric resistant coating that is coated on it, which is characterized by The inner layer was made This is caused by at least two diffusion layers whose permeability for the active ingredient decreases. From inside to outside And methods for producing these substances
Claims (2)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH97797B true TH97797B (en) | 2009-08-20 |
| TH97797A TH97797A (en) | 2009-08-20 |
Family
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