TH91884B - Synametic compounds of morpholine type - Google Patents
Synametic compounds of morpholine typeInfo
- Publication number
- TH91884B TH91884B TH601005836A TH0601005836A TH91884B TH 91884 B TH91884 B TH 91884B TH 601005836 A TH601005836 A TH 601005836A TH 0601005836 A TH0601005836 A TH 0601005836A TH 91884 B TH91884 B TH 91884B
- Authority
- TH
- Thailand
- Prior art keywords
- group
- compounds
- atom
- synametic
- oxygen
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- YNAVUWVOSKDBBP-UHFFFAOYSA-N morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 title 1
- 229940113083 morpholine Drugs 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 3
- 239000011780 sodium chloride Substances 0.000 claims abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atoms Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004430 oxygen atoms Chemical group O* 0.000 abstract 2
- -1 Pyridinyl Oxy groups Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N oxygen atom Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวกับสารประกอบซึ่งแทนด้วยสูตร (I) (สูตรเคมี) (I) หรือเกลือซึ่งเป็นที่ยอมรับทางเภสัชกรรมของสารนั้น, ซึ่ง R1, R2, R3, และ R4 เหมือนกัน หรือแตกต่างกันและแต่ละหมู่คือไฮโดรเจน อะตอม หรือ หมู่ C1-6 แอลคิล; X1 คือหมู่ C1-6 แอลคิลีน ซึ่งอาจถูกแทนที่; Xa คือหมู่เมธอกซิ หรือฟลูออรีน อะตอม; Xb คือออกซิเจน อะตอม หรือหมู่เมธิลีน, โดยมีข้อกำหนดคือ Xb คือออกซิเจน อะตอมเท่า นั้นเมื่อ Xa คือหมู่เมธอกซิ; และ Ar1 คือหมู่แอริล, หมู่พิริดินิล, หมู่แอริลออกซิหรือ หมู่พิริดินิลออกซิซึ่งอาจมีหมู่แทนที่เช่นเฮโลเจน อะตอม; และเกี่ยวกับการใช้สารประกอบหรือ เกลือเป็นสารเภสัชกรรม.: This invention deals with compounds represented by the formula (I) (chemical formula) (I) or a chemically acceptable salt of that substance, in which R1, R2, R3, and R4 are the same or different, and each group is Hydrogen atom or group C1-6 alkyl; X1 is group C1-6 alkylines which may be replaced; Xa is a methoxy or fluorine atom; Xb is the oxygen atom or methylene group, with the definition Xb is the oxygen atom only when Xa is the methoxin group; And Ar1 is the aryl group, the Pyridinil group, the aryl oxygen group or Pyridinyl Oxy groups, which may have a substitution group, such as a halogen atom; And about using compounds or Salt is a pharmaceutical substance.:
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH91884A TH91884A (en) | 2008-10-20 |
| TH91884B true TH91884B (en) | 2008-10-20 |
Family
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