TH84979B - CGRP-selective antagonist, a process for preparing them. And the use of those substances as pharmaceutical mixtures - Google Patents
CGRP-selective antagonist, a process for preparing them. And the use of those substances as pharmaceutical mixturesInfo
- Publication number
- TH84979B TH84979B TH501001385A TH0501001385A TH84979B TH 84979 B TH84979 B TH 84979B TH 501001385 A TH501001385 A TH 501001385A TH 0501001385 A TH0501001385 A TH 0501001385A TH 84979 B TH84979 B TH 84979B
- Authority
- TH
- Thailand
- Prior art keywords
- cgrp
- preparing
- those substances
- selective antagonist
- pharmaceutical mixtures
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 102000033175 CALCA Human genes 0.000 title abstract 2
- 101700017623 CALCA Proteins 0.000 title abstract 2
- 101700041770 CALCR Proteins 0.000 title abstract 2
- 101710023382 S100A12 Proteins 0.000 title abstract 2
- 230000003042 antagnostic Effects 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 claims 5
- 125000004430 oxygen atoms Chemical group O* 0.000 claims 2
- 229910052717 sulfur Chemical group 0.000 claims 2
- 125000004434 sulfur atoms Chemical group 0.000 claims 2
- 239000003735 calcitonin gene related peptide receptor antagonist Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atoms Chemical group N* 0.000 claims 1
- 235000015277 pork Nutrition 0.000 claims 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000011780 sodium chloride Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000036571 hydration Effects 0.000 abstract 1
- 238000006703 hydration reaction Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
Abstract
การประดิษฐ์นี้ เกี่ยวกับ CGRP แอนทาโกนิสท์ ของสูตรทั่วไป (สูตรเคมี) , (I) ซึ่ง A, X, D, E, G, M, Q และ R1 ถึง R3 มีความหมายตามที่ได้นิยามไว้ในข้อถือสิทธิข้อ 1, ทอโนเมอร์, ไอโซเมอร์, ไดแอสเทอริโอเมอร์, อิแนนชิโอเมอร์, ไฮเดรทของสารนั้น, ของ ผสมของสารเหล่านั้นและเกลือของสารนั้นและไฮเดรทของเกลือ, โดยเฉพาะ เกลือของสารนั้นซึ่งเป็น ที่ยอมรับทางสรีรวิทยาด้วยกรดอนินทรีย์หรืออินทรีย์, สารผสมทางเภสัชกรรมที่สารประกอบ เหล่านั้น, การใช้ของสารนั้นและกรรมวิธีสำหรับเตรียมของสารนั้น This invention is about CGRP, the antagonist of the general formula (chemical formula), (I), in which A, X, D, E, G, M, Q and R1 to R3 have meaning as defined in Claim No. 1, Tonsomers, Isomers, Diasteriomers, Inanciomers, Hydrates of Such Substances, Mixtures of Them And the salt of that substance and the hydration of the salt, especially the salt of that substance which is Physiologically acceptable inorganic or organic acids, pharmaceutical mixtures of those compounds, their use and methods for their preparation.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH84979A TH84979A (en) | 2007-06-14 |
| TH84979B true TH84979B (en) | 2007-06-14 |
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