TH82513A - Acetylene-pyrazolo-pyrimidine derivative is mGluR2 antagonist. - Google Patents
Acetylene-pyrazolo-pyrimidine derivative is mGluR2 antagonist.Info
- Publication number
- TH82513A TH82513A TH601001260A TH0601001260A TH82513A TH 82513 A TH82513 A TH 82513A TH 601001260 A TH601001260 A TH 601001260A TH 0601001260 A TH0601001260 A TH 0601001260A TH 82513 A TH82513 A TH 82513A
- Authority
- TH
- Thailand
- Prior art keywords
- substance
- pyrazolo
- acetylene
- pyrimidine derivative
- mglur2 antagonist
- Prior art date
Links
- -1 Acetylene-pyrazolo-pyrimidine derivative Chemical class 0.000 title 1
- 102100006616 GRM2 Human genes 0.000 title 1
- 230000003042 antagnostic Effects 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 108010038421 metabotropic glutamate receptor 2 Proteins 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 9
- 239000003814 drug Substances 0.000 claims abstract 4
- 229940079593 drugs Drugs 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 102100004109 HEY1 Human genes 0.000 claims 1
- 108010081348 HRT1 protein Hairy Proteins 0.000 claims 1
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000001225 therapeutic Effects 0.000 abstract 2
Abstract
DC60 การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบที่มีสูตร (I) (สูตรเคมี) (l) กระบวนการสำหรับการผลิตสารนั้น การใช้สารนั้นสำหรับการเตรียมยารักษาโรคสำหรับการบำบัด ความผิดปกติ CNS และสารผสมทางเภสัชกรรมที่มีสารนั้น ที่ซึ่ง R1 ถึง R3, A, M, L, E, G, และ J เป็น ดังที่นิยามในคำอธิบายและข้อถือสิทธิ การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบที่มีสูตร (I): (สูตรเคมี) (l) กระบวนการสำหรับการผลิตสารนั้น การใช้สารนั้นสำหรับการเตรียมยารักษาโรคสำหรับการบำบัด ความผิดปกติ CNS และสารผสมทางเภสัชกรรมที่มีสารนั้น ที่ซึ่ง R1 ถึง R3, A, M, L, E, G, และ J เป็น ดังที่นิยามในคำอธิบายและข้อถือสิทธิ: สิทธิบัตรยา DC60 This invention involves a compound with formula (I) (chemical formula) (l), a process for the production of that substance. The use of the substance for the preparation of a therapeutic drug for the treatment of CNS disorders and pharmaceutical mixtures containing that substance, where R1 to R3, A, M, L, E, G, and J is defined in the terms Explain and claim This invention involves a compound with the formula (I): (chemical formula) (l), a process for the production of that substance. The use of the substance for the preparation of a therapeutic drug for the treatment of CNS disorders and pharmaceutical mixtures containing that substance, where R1 to R3, A, M, L, E, G, and J is defined in the terms Explain and disclaimer: drug patent
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH82513B TH82513B (en) | 2007-01-18 |
| TH82513A true TH82513A (en) | 2007-01-18 |
Family
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