TH82148A - Compounds for the treatment of inflammatory disorders - Google Patents
Compounds for the treatment of inflammatory disordersInfo
- Publication number
- TH82148A TH82148A TH501003231A TH0501003231A TH82148A TH 82148 A TH82148 A TH 82148A TH 501003231 A TH501003231 A TH 501003231A TH 0501003231 A TH0501003231 A TH 0501003231A TH 82148 A TH82148 A TH 82148A
- Authority
- TH
- Thailand
- Prior art keywords
- alkyl
- treatment
- compounds
- formula
- inflammatory disorders
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims abstract 3
- 239000012453 solvate Substances 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000000217 alkyl group Chemical group 0.000 claims 5
- LFVPBERIVUNMGV-UHFFFAOYSA-N fasudil hydrochloride Chemical compound Cl.C=1C=CC2=CN=CC=C2C=1S(=O)(=O)N1CCCNCC1 LFVPBERIVUNMGV-UHFFFAOYSA-N 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- -1 heteroeryl Chemical group 0.000 claims 1
- 102000029791 ADAM Human genes 0.000 abstract 2
- 108091022885 ADAM Proteins 0.000 abstract 2
- 102100031111 Disintegrin and metalloproteinase domain-containing protein 17 Human genes 0.000 abstract 2
- 101000777461 Homo sapiens Disintegrin and metalloproteinase domain-containing protein 17 Proteins 0.000 abstract 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 2
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 2
- BFPSDSIWYFKGBC-UHFFFAOYSA-N chlorotrianisene Chemical compound C1=CC(OC)=CC=C1C(Cl)=C(C=1C=CC(OC)=CC=1)C1=CC=C(OC)C=C1 BFPSDSIWYFKGBC-UHFFFAOYSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
Abstract
DC60 (05/08/48) การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบของสูตร (I); (สูตรเคมี) (I) หรือเกลือ, โซลเวตหรือไอโซเมอร์ที่ยอมรับทางเภสัชกรรมของมัน ซึ่งสามารถเป็น ประโยชน์สำหรับการรักษาโรคหรือสภาวะที่เกิดจาก MMPs, ADAMs, TACE, TNF- หรือการรวม กันของมัน การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบของสูตร (I); (สูตรเคมี) (I) หรือเกลือ, โซลเวตหรือไอโซเมอร์ที่ยอมรับทางเภสัชกรรมของมัน ซึ่งสามารถเป็น ประโยชน์สำหรับการรักษาโรคหรือสภาวะที่เกิดจาก MMPs, ADAMs, TACE, TNF- หรือการรวม กันของมัน สิทธิบัตรยา DC60 (05/08/48). This invention relates to the compound of formula (I); (Chemical formula) (I) or its salt, solvate, or isomer Which can be Useful for the treatment of diseases or conditions caused by MMPs, ADAMs, TACE, TNF- or a combination of them, this invention involves a compound of formula (I); (Chemical formula) (I) or its salt, solvate, or isomer Which can be Useful for treating diseases or conditions caused by MMPs, ADAMs, TACE, TNF- or a combination of it.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH82148A true TH82148A (en) | 2007-01-04 |
Family
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