TH68037A - Compounds for the treatment of inflammatory diseases - Google Patents
Compounds for the treatment of inflammatory diseasesInfo
- Publication number
- TH68037A TH68037A TH201004753A TH0201004753A TH68037A TH 68037 A TH68037 A TH 68037A TH 201004753 A TH201004753 A TH 201004753A TH 0201004753 A TH0201004753 A TH 0201004753A TH 68037 A TH68037 A TH 68037A
- Authority
- TH
- Thailand
- Prior art keywords
- treatment
- formula
- compounds
- inflammatory diseases
- chemical formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 5
- 239000003814 drug Substances 0.000 claims abstract 3
- 150000003839 salts Chemical class 0.000 claims abstract 3
- 229940079593 drug Drugs 0.000 claims abstract 2
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- -1 eryl Chemical group 0.000 claims 1
- LFVPBERIVUNMGV-UHFFFAOYSA-N fasudil hydrochloride Chemical compound Cl.C=1C=CC2=CN=CC=C2C=1S(=O)(=O)N1CCCNCC1 LFVPBERIVUNMGV-UHFFFAOYSA-N 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000005343 heterocyclic alkyl group Chemical group 0.000 claims 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 1
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 abstract 2
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
Abstract
DC60 การประดิษฐ์เกี่ยวข้องกับสารประกอบของสูตร (I) (สูตรเคมี) (I) หรือ เกลือ, ซอลเวท หรือ ไอโซเมอร์ของมันที่เป็นที่ยอมรับในทางเภสัชกรรม, :ซึ่งสามารถเป็น ประโยชน์สำหรับการรักษาโรคหรือสภาวะที่สื่อผ่านจาก MMPs, TNF-อัลฟา, หรือ การรวมกันของ สารเหล่านั้น การประดิษฐ์เกี่ยวข้องกับสารประกอบของสูตร (I): (สูตรเคมี) (I) หรือ เกลือ, ซอลเวท หรือ ไอโซเมอร์ของมันที่เป็นที่ยอมรับในทางเภสัชกรรม, :ซึ่งสามารถเป็น ประโยชน์สำหรับการรักษาโรคหรือสภาวะที่สื่อผ่านจาก MMPs, TNF-อัลฟา, หรือ การรวมกันของ สารเหล่านั้น: สิทธิบัตรยา DC60 The invention involves a compound of formula (I) (chemical formula) (I) or a salt, salvate or isomer of it that is well established in pharmaceuticals,: which can be Benefits for the treatment of diseases or conditions transmitted by MMPs, TNF-alpha, or a combination of those substances.The invention involves a compound of formula (I): (chemical formula) (I) or salt, salvate. Or isomers of it that are recognized in a pharmaceutical field,: which can be Useful for the treatment of diseases or conditions transmitted by MMPs, TNF-alpha, or a combination of those substances: drug patents.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH68037A true TH68037A (en) | 2005-03-24 |
Family
ID=
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