TH80311B - Solid dosage form containing a proton pump inhibitor and a suspension made from the above dosage form. - Google Patents
Solid dosage form containing a proton pump inhibitor and a suspension made from the above dosage form.Info
- Publication number
- TH80311B TH80311B TH501006038A TH0501006038A TH80311B TH 80311 B TH80311 B TH 80311B TH 501006038 A TH501006038 A TH 501006038A TH 0501006038 A TH0501006038 A TH 0501006038A TH 80311 B TH80311 B TH 80311B
- Authority
- TH
- Thailand
- Prior art keywords
- dosage form
- proton pump
- pump inhibitor
- granulation
- suspension
- Prior art date
Links
- 239000000725 suspension Substances 0.000 title claims abstract 4
- 230000003482 proton pump inhibitor Effects 0.000 title claims abstract 3
- 239000000612 proton pump inhibitor Substances 0.000 title claims abstract 3
- 239000002552 dosage form Substances 0.000 title 1
- 239000007909 solid dosage form Substances 0.000 title 1
- 238000005469 granulation Methods 0.000 claims abstract 4
- 230000003179 granulation Effects 0.000 claims abstract 4
- 239000002253 acid Substances 0.000 claims abstract 2
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 230000000968 intestinal Effects 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 2
- 239000006186 oral dosage form Substances 0.000 claims abstract 2
- 239000007787 solid Substances 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 239000003349 gelling agent Substances 0.000 claims 1
- 239000003002 pH adjusting agent Substances 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 229940082509 xanthan gum Drugs 0.000 claims 1
- 235000010493 xanthan gum Nutrition 0.000 claims 1
- 239000000230 xanthan gum Substances 0.000 claims 1
- 229940077718 Proton pump inhibitors for peptic ulcer and GORD Drugs 0.000 abstract 1
- 210000002249 digestive system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Abstract
รูปแบบยาสำหรับให้ทางปากที่เป็นเจลอย่างรวดเร็วชนิดของแข็ง, เช่นเดียวกับ ยาแขวนตะกอน ชนิดเอเควียสที่เตรียมจากสารดังกล่าว, ซึ่งประกอบรวมด้วย ตัวยับยั้งการปั๊มโปรตอนที่ไวต่อกรดที่เป็น ส่วนประกอบออกฤทธิ์ที่กระจายอยู่ในยาลูกกลอนเคลือบเพื่อปลดปล่อยในลำไส้จำนวนมาก และ แกรนูล ที่ดัดแปรการแขวนตะกอน นอกจากนี้ การประดิษฐ์นี้เกี่ยวข้องกับกระบวนการที่ปรับปรุงสำหรับการ ผลิตสารดังกล่าว และการใช้สูตรผสมดังกล่าวในการรักษาโรค ซึ่งรวมถึง การป้องกันอาการผิดปกติเกี่ยว กับระบบทางเดินอาหารในมนุษย์ The oral dosage form is a solid rapid gel, as well as the AKAVase-type suspension prepared from it, which includes: Acid-sensitive proton pump inhibitors The active ingredients are distributed in bulk intestinal coated bolus and modified granulation, suspension. In addition, this invention involves an improved process for the Produce such substances And the use of such formulations in the treatment of diseases, including the prevention of symptoms associated with With the human digestive system
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH80311A TH80311A (en) | 2006-10-12 |
TH80311B true TH80311B (en) | 2006-10-12 |
Family
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