TH77463B - Derivatives of 3-guanidinocarbonyl-1-heteroeryl-perroll, process of preparation and substance of this process, use of such substances as drugs. And pharmaceutical mixtures containing such substances - Google Patents
Derivatives of 3-guanidinocarbonyl-1-heteroeryl-perroll, process of preparation and substance of this process, use of such substances as drugs. And pharmaceutical mixtures containing such substancesInfo
- Publication number
- TH77463B TH77463B TH301002610A TH0301002610A TH77463B TH 77463 B TH77463 B TH 77463B TH 301002610 A TH301002610 A TH 301002610A TH 0301002610 A TH0301002610 A TH 0301002610A TH 77463 B TH77463 B TH 77463B
- Authority
- TH
- Thailand
- Prior art keywords
- substances
- perroll
- heteroeryl
- guanidinocarbonyl
- derivatives
- Prior art date
Links
Abstract
อนุพันธ์ 3-กัวนิดิโนคาร์โบนิล-1-เฮเทอโรแอริล-พีร์โรลตามสูตร (I) (สูตรเคมี) (I) โดยที่ R1 ถึง R3 และ Ar มีความหมายตามที่ระบุในข้อถือสิทธิ สารประกอบตามการประดิษฐ์นี้มี ความเหมาะสมตัวอย่างเช่นในฐานะยาต้านภาวะหัวใจเสียจังหวะซึ่งมีส่วนประกอบคุ้มครองหัวใจ สำหรับป้องกันเนื้อตายเหตุขาดเลือดและรักษาเนื้อตายเหตุขาดเลือด และสำหรับรักษาแองไจนา เพกทอริส นอกจากนี้สารเหล่านี้ในเชิงป้อนกันยังยับยั้งกระบวนการทางสรีรพยาธิสภาพที่เกี่ยวข้อง กับความเกิดความเสียหายซึ่งชักนำโดยการขาดเลือดเฉพาะที่ โดยเฉพาะอย่างยิ่งในการกระตุ้นให้เกิด ภาวะหัวใจเสียจังหวะซึ่งชักนำโดยการขาดเลือดเฉพาะที่ และหัวใจล้มเหลว 3-guanidinocarbonyl-1-heteroeryl-perroll derivatives according to the formula (I) (chemical formula) (I), where R1 to R3 and Ar have the specified meanings. In the claim Compounds according to this invention have Suitability, for example, as an anti-arrhythmia drug with a heart protection component. For prevention of ischemic necrosis and treatment of ischemic necrosis And for the treatment of angina pectorris. In addition, these substances mutually inhibit the physiological processes involved. With damage induced by local ischemia Especially in the urge to Heart failure, induced by local ischemia And heart failure
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH77463A TH77463A (en) | 2006-05-18 |
| TH77463B true TH77463B (en) | 2006-05-18 |
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