TH60263A - 1,4-diazabycloid derivatives [3.2.2] nonane-phenylisoxazole, such preparations and therapeutic use. - Google Patents
1,4-diazabycloid derivatives [3.2.2] nonane-phenylisoxazole, such preparations and therapeutic use.Info
- Publication number
- TH60263A TH60263A TH101002083A TH0101002083A TH60263A TH 60263 A TH60263 A TH 60263A TH 101002083 A TH101002083 A TH 101002083A TH 0101002083 A TH0101002083 A TH 0101002083A TH 60263 A TH60263 A TH 60263A
- Authority
- TH
- Thailand
- Prior art keywords
- alkyl
- represent hydrogen
- groups
- represent
- atoms
- Prior art date
Links
- DYADEGRGWZBJHV-UHFFFAOYSA-N C1(=CC=CC=C1)C1=NOC=C1.CCCCCCCCC Chemical compound C1(=CC=CC=C1)C1=NOC=C1.CCCCCCCCC DYADEGRGWZBJHV-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 7
- -1 cyano, hydroxyl Chemical group 0.000 claims abstract 6
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 206010011703 Cyanosis Diseases 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Abstract
DC60 (30/07/44) สารประกอบตามสูตรทั่วไป (I) (สูตรเคมี) (I) โดยที่ R1, R2, R3, R4 และ R5 โดยอิสระจากกันต่างแทนอะตอมของไฮโดรเจนหรือฮาโลเจน หรือหมู่ ไนโตร, อะมิโน, ไตรฟลูออโรเมทิล, ไตรฟลูออโรเมทอกซี, ไซยาโน, ไฮดรอกซิล, (C1-C6) แอลคิล, (C1-C6)แอลคอกซี หรือเฟนิล นอกจากนี้ยังเป็นไปได้ที่หมู่แทนที่เหล่านี้สองหมู่ในตำแหน่งที่ติดกัน จะร่วมกันแทนหมู่เมทิลีนไดออกซี และ R6 แทนอะตอมของไฮโดรเจนหรือหมู่ (C1-C6)แอลคิล การใช้ในการบำบัด สารประกอบตามสูตรทั่วไป (I) (สูตรเคมี) (I) โดยที่ R1, R2, R3, R4 และ R5 โดยอิสระจากกันต่างแทนอะตอมของไฮโดรเจนหรือฮาโลเจน หรือหมู่ ไนโตร, อะมิโน, ไตรฟลูออโรเมทิล, ไตรฟลูออโรเมทอกซี, ไซยาโน, ไฮดรอกซิล, (C1-C6)แอลคิล, (C1-C6)แอลคอกซี หรือเฟนิล นอกจากนี้ยังเป็นไปได้ที่หมู่แทนที่เหล่านี้สองหมู่ในตำแหน่งที่ติดกัน จะร่วมกันแทนหมู่เมทิลีนไดออกซี และ R6 แทนอะตอมของไฮโดรเจนหรือหมู่ (C1-C6)แอลคิล การใช้ในการบำบัด สิทธิบัตรยา DC60 (30/07/44) Compounds according to the general formula (I) (Chemical formula) (I), where R1, R2, R3, R4 and R5 independently of each other represent hydrogen or halogen atoms or nitro groups. , Amino, trifluoromethyl, trifluoromethoxy, cyano, hydroxyl, (C1-C6) alkyl, (C1-C6) alkyl Or phenyl.It is also possible that these two substitutions are in adjacent positions. Together they represent methylene dioxins and R6 represent hydrogen atoms or groups. (C1-C6) alkyl Use in therapy Compounds according to the general formula (I) (chemical formula) (I), where R1, R2, R3, R4 and R5, independently of each other, represent hydrogen or halogen atoms or nitro, amino, triflu atoms. Oromethyl, trifluoromethoxy, cyanos, hydroxyl, (C1-C6) alkyl, (C1-C6) alkoxy or phenyl are also possible. It can be that these two displacement groups are placed next to each other. Together they represent methylene dioxins and R6 represent hydrogen atoms or groups. (C1-C6) alkyl Use in drug patent treatment
Claims (2)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH60263A true TH60263A (en) | 2004-01-09 |
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