TH6013B - Methods for working of cat ion exchange resins in a process for the separation of basic amino acids from the aforementioned solutions. - Google Patents

Abstract

How cations exchange resins work, which consists of connecting a large number of cations exchange resin towers in series. and repeating the absorption and elution of base amino acids while moving the tower accordingly. Methods for the operation of cation exchange resins in a method used to separate amino acid bases. which consists of reverse circulation of the last part of the liquid at the tip from the earliest chamber connected to the same type of procedure.

Claims (9)

1. Procedures for the separation of base amino acids from liquids containing the same substance. By using toocat ion exchange A series of resins that consist of repetitive sequential adsorption and elution steps where the rinsing water used in the rinsing and elution process is obtained by recirculation. The latter end of the liquid released from the earliest tower at the adsorption stage to the adsorption stage in an interlocking cycle or by recirculation of the liquid released from the earliest tower at the E. stage. Luzion to an elution phase in a contiguous cycle 2. Process according to claim 1, where the repeated absorption and elution procedures are performed using a two (2) tower-two (2) adsorption tower. (3) Three (3) elution tower or four (4) elution tower - four (4) elution tower. 3. Procedures according to claim 2, where the repeated absorption and elution procedures are performed using a three (3) tower-elu adsorption and throttle-type operation. Three (3) towers, which are R1, R2 and R3. 4. The process according to claim 3, wherein the adsorption phase of the start-up will consist of (a) the connection of each tower R1, R2 and R3 in series and through the amino acid liquid. One or more bases from the R1 tower are followed by the flushing water through the section, then (b) the discharge of the solution containing low concentrations of impurities in it, starting with the R3 tower. The solution with a highly concentrated impurity exited then (c) brought the R1 tower to reverse wash and (d) repeated the above circuit twice while moving from tower to tower sequentially. 5. Procedures according to claim 3, where the elution phase of the start-up will consist of (a) the individual connections of the R1, R2 and R3 towers as subordinate and eluting. The agent from the R1 tower is followed by a flushing water through the section, then (b) the discharge of the solution from the R3 tower and subsequently emits one or more of the amino acid-base emulsions. out 6. Process according to claim 3, where static work will consist of: (a) adsorption process. It consists of (1) the connections of each tower R4, R5 and R1 are in series and through the liquid with one or more such amino acid bases and subsequently as flushing water from the R4 tower and ( 2) the introduction of the R4 tower for backwash and (b) the elution procedure It consists of (1) connecting each of the R2, R3 and R4 towers in series. And through the eluting agent and later rinsing water from the R2 tower and (c) repeating the process of absorption and elution as it moves from one tower to the next. In order 7. Process according to claim 1, where the Cation Exchange Resins are resins in the form of ammonium type or sodium type. 8. Procedure according to claim 1, where the amino acid base is lysine, arginine, ornithine or histidine or a mixture of these substances. 9. Procedure according to claim 1, where a liquid containing one or more of the aforementioned amino acid bases is a sterile fermentation. A liquid obtained by separating bacteria from the sterile fermentation A solution of crystals of one or more of the aforementioned amino acids The parent solution of crystallization of the same substance or amino acid liquid. Base type obtained from protene hydrolyzate 1 0. Process according to claim 1, where Eluzion The agent is a solution of ammonia. Sodium hydroxide Or sodium chloride