TH52229B - Strains with an arginine-deficient inhibitor of the corineform bacteria And methods for the production of L-arginine - Google Patents

Abstract

DC60 (12/07/44) L-arginine is produced by the cultures of coryoform bacteria in which arginine-associated inhibitors. Involved in synthesis L-arginine biological is deducted by disintegration of genes that decipher the inhibitor and where it is capable of producing. L-arginine in the medium for the production and accumulation of L-arginine in the medium and the collection of L-arginine from this medium. L-arginine is produced by the culture of chorineforms where arginine-associated inhibitors Involved in synthesis L-arginine biological is deducted by disintegration of genes that decipher the inhibitor and where it is capable of producing. L-arginine in the medium for the production and accumulation of L-arginine in the medium and the collection of L-arginine from this medium.

Claims (4)

1. Coryneform bacteria in which arginine inhibitors do not function normally and which are capable of producing L-arginine. 2. Coryneform bacteria according to claim 1, where the arginine inhibitor does not function normally due to the breakup of the gene transcribing the arginine inhibitor on the bacterial chromosome. 3. Coryneform bacteria pursuant to claim 2, where the arginine inhibitor has an amino acid sequence shown in sequence 18 or an amino acid sequence that is similar to that sequence. 4. A method for the production of L-arginine, which involves the cultivation of coryneform bacteria according to one of the claims 1-3 in a medium for the production and accumulation of L-arginine in the medium and the collection of L-arginine from this medium.