TH52229B - Strains with an arginine-deficient inhibitor of the corineform bacteria And methods for the production of L-arginine - Google Patents

Abstract

DC60 (12/07/44) L-arginine is produced by culturing Coryneform bacteria where arginine inhibitors involved in L-arginine biosynthesis are removed by cleavage of the inhibitor transcript gene, and where L-arginine is produced in an intermediate for the production and accumulation of L-arginine in the intermediate, and L-arginine is collected from this intermediate.

Claims (4)

1. Coryneform bacteria in which arginine inhibitors do not function normally and which are capable of producing L-arginine. 2. Coryneform bacteria according to claim 1, where the arginine inhibitor does not function normally due to the breakup of the gene transcribing the arginine inhibitor on the bacterial chromosome. 3. Coryneform bacteria pursuant to claim 2, where the arginine inhibitor has an amino acid sequence shown in sequence 18 or an amino acid sequence that is similar to that sequence. 4. A method for the production of L-arginine, which involves the cultivation of coryneform bacteria according to one of the claims 1-3 in a medium for the production and accumulation of L-arginine in the medium and the collection of L-arginine from this medium.